Efficacy analysis of three-year subcutaneous SQ-standardized specific immunotherapy in house dust mite-allergic children with asthma

Experimental and Therapeutic Medicine

Volumn 7, Issue 3, 2014, Pages 630-634

  Hui, Yu ^a   Li, Ling ^a   Qian, Jun ^a   Guo, Yun ^a   Zhang, Xilian ^a   Zhang, Xiaojuan ^a  

^a The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University   (China)

Author keywords

Asthma; Children; House dust mite; Inhaled corticosteroids; SQ standardized specific immunotherapy

Indexed keywords

EID: 84892994229     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2014.1469     Document Type: Article

References (21)

1. Carrard A and Pichler C: House dust mite allergy. Ther Umsch 69: 249-252, 2012 (In German).
2. Barnes PJ: New drugs for asthma. Semin Respir Crit Care Med 33: 685-694, 2012.
3. Wang CM and Chuang JJ: Effect of mite allergen immunotherapy on the altered phenotype of dendritic cells in allergic asthmatic children. Ann Allergy Asthma Immunol 110: 107-112, 2013.
4. Maazi H, Shirinbak S, Willart M, et al: Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy. Clin Exp Allergy 42: 1519-1528, 2012.
5. Eifan AO, Akkoc T, Yildiz A, Keles S, Ozdemir C, Bahceciler NN and Barlan IB: Clinical efficacy and immunological mechanisms of sublingual and subcutaneous immunotherapy in asthmatic/rhinitis children sensitized to house dust mite: an open randomized controlled trial. Clin Exp Allergy 40: 922-932, 2010.
6. Blumberga G, Groes L and Dahl R: SQ-standardized house dust mite immunotherapy as an immunomodulatory treatment in patients with asthma. Allergy 66: 178-185, 2011.
7. The Breathing Group of Pediatric Academy affiliated to Chinese Medical Association and the Editorial Board of Chinese Journal of Pediatrics affiliated to Chinese Medical Association: The routine for prevention and treatment of bronchial asthma in children (for trial). Zhonghua Er Ke Za Zhi 42: 100-106, 2004 (In Chinese).
8. Yang BZ, Chen HB, Hou JM, et al: Clinical analysis on 520 children with bronchial asthma of allergens by skin prick test. Journal of North Sichuan Medical College 26: 331-333, 2011 (In Chinese).
9. Akdis CA and Akdis M: Mechanisms of allergen-specific immunotherapy. J Allergy Clin Immunol 127: 18-27, 2011.
10. Han J, Huang Y and Wang MK: Influence of specific immunotherapy on Dermatophagoides pteronyssinus-specific IgG4 and pulmonary function in children suffering from allergic asthma. Journal of Third Military Medical University 33: 618-620, 2011 (In Chinese).
11. Cox L, Calderón M and Pfaar O: Subcutaneous allergen immunotherapy for allergic disease: examining efficacy, safety and cost-effectiveness of current and novel formulations. Immunotherapy 4: 601-616, 2012.
12. Gonzales M, Fratianni C, Mamillapali C and Khardori R: Immunotherapy in miscellaneous medical disorders Graves ophthalmopathy, asthma, and regional painful syndrome. Med Clin North Am 96: 635-654, 2012.
13. Trebuchon F, David M and Demoly P: Medical management and sublingual immunotherapy practices in patients with house dust mite-induced respiratory allergy: a retrospective, observational study. Int J Immunopathol Pharmacol 25: 193-206, 2012.
14. Hedlin G and van Hage M: The role of immunotherapy in the management of childhood asthma. Ther Adv Respir Dis 6: 137-146, 2012.
15. La Rosa M, Lionetti E, Leonardi S, et al: Specific immunotherapy in children: the evidence. Int J Immunopathol Pharmacol 24: 69-78, 2011.
16. Stelmach I, Sobocińska A, Majak P, Smejda K, Jerzyńska J and Stelmach W: Comparison of the long-term efficacy of 3-and 5-year house dust mite allergen immunotherapy. Ann Allergy Asthma Immunol 109: 274-278, 2012.
17. Eifan AO, Shamji MH and Durham SR: Long-term clinical and immunological effects of allergen immunotherapy. Curr Opin Allergy Clin Immunol 11: 586-593, 2011.
18. Klimek L, Mewes T, Wolf H, Hansen I, Schnitker J and Mann WJ: The effects of short-term immunotherapy using molecular standardized grass and rye allergens compared with symptomatic drug treatment on rhinoconjunctivitis symptoms, skin sensitivity, and specific nasal reactivity. Otolaryngol Head Neck Surg 133: 538-543, 2005.
19. Creticos PS: The consideration of immunotherapy in the treatment of allergic asthma. J Allergy Clin Immunol 105: S559-S574, 2000.
20. Frew AJ: 25. Immunotherapy of allergic disease. J Allergy Clin Immunol 111 (Suppl 2): S712-S719, 2003.
21. Mellerup MT, Hahn GW, Poulsen LK and Malling H: Safety of allergen-specific immunotherapy. Relation between dosage regimen, allergen extract, disease and systemic side-effects during induction treatment. Clin Exp Allergy 30: 1423-1429, 2000.