Innate immune response adaptation in mice subjected to administration of DMBA and physical activity

Oncology Letters

Volumn 7, Issue 3, 2014, Pages 886-890

  Abdalla, Douglas R ^a   Rocha Aleixo, André Adriano ^a   Murta, Eddie F C ^a   Michelin, Márcia Antoniazi ^a  

^a FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

Author keywords

Cancer; Immune response; Physical activity; Tumor

Indexed keywords

4 DIMETHYLAMINOBENZALDEHYDE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; MOUSE; NEOPLASM; NONHUMAN; PERITONEUM MACROPHAGE; PHYSICAL ACTIVITY; PROTEIN EXPRESSION; SOLID TUMOR;

EID: 84892986065     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2013.1774     Document Type: Article

References (23)

1. van Furth R, Cohn ZA, Hirsch JG, Humphrey JH, Spector WG and Langevoort HL: The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells. Bull World Health Organ46: 845-852, 1972.
2. Mackaness GB: The immunological basis of acquired cellular resistance. J Exp Med120: 105-120, 1964.
3. Gordon S and Taylor PR: Monocyte and macrophage heterogeneity. Nat Rev Immunol5: 953-964, 2005.
4. Gordon S: The macrophage: past, present and future. Eur J Immunol37 (Suppl1): S9-S17, 2007.
5. Gordon S: Alternative activation of macrophages. Nat Rev Immunol3: 23-35, 2003.
6. Martinez FO, Helming L and Gordon S: Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol27: 451-483, 2009.
7. Mills CD, Kincaid K, Alt JM, Heilman MJ and HillAM: M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol164: 6166-6173, 2000.
8. Lefèvre L, Galès A, Olagnier D, Bernad J, Perez L, etal: PPARγ ligands switched high fat diet-induced macrophage M2b polarization toward M2a thereby improving intestinal Candida elimination. PLoS One5: e12828, 2010.
9. Mantovani A, Bottazzi B, Colotta F, Sozzani S and RucoL: The origin and function of tumor-associated macrophages. Immunol Today13: 265-270, 1992.
10. Mantovani A, Schioppa T, Porta C, Allavena P and Sica A: Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev25: 315-322, 2006.
11. Sica A, Larghi P, Mancino A, Rubino L, Porta C, Totaro MG, etal: Macrophage polarization in tumour progression. Semin Cancer Biol18: 349-355, 2008.
12. Dannenmann SR, Thielicke J, Stöckli M, Matter C, vonBoehmrL, Cecconi V, Hermanns T, Hefermehl L, SchramlP, Moch H, etal: Tumor-associated macrophages subvert T-cell function and correlate with reduced survival in clear cell renal cell carcinoma. Oncoimmunology2: e23562, 2013.
13. Woods JA: Exercise and resistance to neoplasia. Can J Physiol Pharmacol76: 581-588, 1998.
14. Pedersen BK and Hoffman-GoetzL: Exercise and the immune system: regulation, integration, and adaptation. Physiol Rev80: 1055-1081, 2000.
15. Cassetta L, Cassol E and Poli G: Macrophage polarization in health and disease. ScientificWorldJournal11: 2391-2402, 2011.
16. Zijlmans HJ, Fleuren GJ, Baelde HJ, Eilers PH, Kenter GG and Gorter A: Role of tumor-derived proinflammatory cytokines GM-CSF, TNF-alpha, and IL-12 in the migration and differentiation of antigen-presenting cells in cervical carcinoma. Cancer109: 556-565, 2007.
17. Kizaki T, Takemasa T, Sakurai T, Izawa T, Hanawa T, KamiyaS, Haga S, Imaizumi K and Ohno H: Adaptation of macrophages to exercise training improves innate immunity. Biochem Biophys Res Commun372: 152-156, 2008.
18. Lu Q, Ceddia MA, Price EA, Ye SM and Woods JA: Chronic exercise increases macrophage-mediated tumor cytolysis in young and old mice. Am J Physiol276: R482-R489, 1999.
19. Woods J, Lu Q, Ceddia MA and Lowder T: Special feature for the Olympics: effects of exercise on the immune system: exercise-induced modulation of macrophage function. Immunol Cell Biol78: 545-553, 2000.
20. Bombarda J, Melo JC, De Souza ER, Nóbrega OT and CórdovaC: Exercise below the anaerobic threshold increases phagocytic and microbicide activities of neutrophils in Wistar rats. J Bras Patol Med Lab45: 9-15, 2009 (In Portuguese).
21. Schmieder A, Michel J, Schönhaar K, Goerdt S and SchledzewskiK: Differentiation and gene expression profile of tumor-associated macrophages. Semin Cancer Biol22: 289-297, 2012.
22. Shirabe K, Mano Y, Muto J, Matono R, Motomura T, Toshima T, Takeishi K, Uchiyama H, Yoshizumi T, TaketomiA, etal: Role of tumor-associated macrophages in the progression of hepatocellular carcinoma. Surg Today42: 1-7, 2012.
23. Abdalla DR, Murta EF and Michelin MA: The influence of physical activity on the profile of immune response cells and cytokine synthesis in mice with experimental breast tumors induced by 7,12-dimethylbenzanthracene. Eur J Cancer Prev22: 251-258, 2013.