Evidence for high genetic diversity of NAD1 and COX1 mitochondrial haplotypes among triclabendazole resistant and susceptible populations and field isolates of Fasciola hepatica (liver fluke) in Australia

Veterinary Parasitology

Volumn 200, Issue 1-2, 2014, Pages 90-96

  Elliott, T ^a   Muller, A ^b   Brockwell, Y ^b   Murphy, N ^c   Grillo, V ^b,d   Toet, H M ^a   Anderson, G ^e   Sangster, N ^b   Spithill, T W ^a,b  

^a LA TROBE UNIVERSITY   (Australia)

^b CHARLES STURT UNIVERSITY   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

^d Australian Wildlife Health Network   (Australia)

^e Virbac (Australia) Pty Ltd   (Australia)

Author keywords

COX1; Fasciola hepatica; Mitochondrial DNA; NAD1; Population genetics; Triclabendazole resistance

Indexed keywords

FLUKARE C; MITOCHONDRIAL DNA; NUCLEOTIDE; TRICLABENDAZOLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUSTRALIA; CATTLE; COX1 GENE; DNA DETERMINATION; DNA SEQUENCE; DRUG RESISTANCE; DRUG SENSITIVITY; FASCIOLA HEPATICA; GENETIC CODE; GENETIC VARIABILITY; GRAZING; HAPLOTYPE; MITOCHONDRIAL GENE; MITOCHONDRION; NAD1 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE ISOLATION; POPULATION DIFFERENTIATION; SHEEP;

BOS; FASCIOLA; FASCIOLA HEPATICA; OVIS ARIES;

COX1; FASCIOLA HEPATICA; MITOCHONDRIAL DNA; NAD1; POPULATION GENETICS; TRICLABENDAZOLE RESISTANCE;

ANIMALS; ANTHELMINTICS; AUSTRALIA; BENZIMIDAZOLES; CATTLE; DNA, MITOCHONDRIAL; DRUG RESISTANCE; ELECTRON TRANSPORT COMPLEX IV; FASCIOLA HEPATICA; GENES, HELMINTH; GENETIC VARIATION; HAPLOTYPES; SHEEP;

EID: 84892895008     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2013.11.019     Document Type: Article

References (30)

1. Ai L., Weng Y.B., Elsheikha H.M., Zhao G.H., Alasaad S., Chen J.X., Li J., Li H.L., Wang C.R., Chen M.X., Lin R.Q., Zhu X.Q. Genetic diversity and relatedness of Fasciola spp. isolates from different hosts and geographic regions revealed by analysis of mitochondrial DNA sequences. Vet. Parasitol. 2011, 181:329-334.
2. Alvarez-Sanchez M., Mainar-Jaime R., Perez-Garcia J., Rojo-Vázquez F. Resistance of Fasciola hepatica to triclabendazole and albendazole in sheep in Spain. Vet. Rec. 2006, 159:424-425.
3. Blair D., Campos A., Cummings M.P., Laclette J.P. Evolutionary biology of parasitic Platyhelminths: the role of molecular phylogenetics. Parasitol. Today 1996, 12:66-71.
4. Boray J.C. Liver Fluke in Sheep and Cattle. Primefact 446 (February 2007) 2007, NSW Department of Primary Industries, Camden, Australia, Retrievable from: http://www.dpi.nsw.gov.au/agriculture/livestock/sheep/health/internal/liverfluke-disease-sheep-cattle.
5. Boray J.C., Crowfoot P.D., Strong M.B., Allison J.R., Schellenbaum M., Vonorelli M., Sarasin G. Treatment of immature and mature Fasciola hepatica infections in sheep with triclabendazole. Vet. Rec. 1983, 113:315-317.
6. Brockwell Y.M., Spithill T.W., Anderson G.R., Grillo V., Sangster N.C. Comparative kinetics of serological and coproantigen ELISA and faecal egg count in cattle experimentally infected with Fasciola hepatica and following treatment with triclabendazole. Vet. Parasitol. 2013, 196:417-426.
7. Brockwell Y.M., Elliott T.P., Anderson G.R., Spithill T.W. and Sangster N.C., in press. Confirmation of Fasciola hepaticaresistant to triclabendazole in naturally infected Australian beef and dairy cattle, Int. J. Parasitol-Drugs Drug Resistance.
8. Dosay-Akbulut M., Trudgett A., Stanhope M. Understanding genetic diversity of the liver fluke Fasciola hepatica. Z. Naturforsch. (C) 2005, 60:774-778.
9. Fairweather I. Liver fluke isolates: a question of provenance. Vet. Parasitol. 2011, 176:1-8.
10. Gordon D., Zadoks R., Skuce P., Sargison N. Confirmation of triclabendazole resistance in liver fluke in the UK. Vet. Rec. 2012, 171:159-160.
11. Itagaki T., Kikawa M., Sakaguchi K., Shimo J., Terasaki K., Shibahara T., Fukuda K. Genetic characterization of parthenogenic Fasciola sp. in Japan on the basis of the sequences of ribosomal and mitochondrial DNA. Parasitology 2005, 131:679-685.
12. Itagaki T., Tsutsumi K.I., Ito K., Tsutsumi Y. Taxonomic status of the Japanese triploid forms of Fasciola: comparison of mitochondrial ND1 and COl sequences with F. hepatica and F. gigantica. J. Parasitol. 1998, 84:445-448.
13. Laird P.P., Boray J.C. Human fasciolisis successfully treated with triclabendazole. Aust. N. Z. J. Med. 1992, 22:45-47.
14. Le T.H., Blair D., McManus D.P. Complete DNA sequence and gene organization of the mitochondrial genome of the liverfluke, Fasciola hepatica L. (Platyhelminthes; Trematoda). Parasitology 2001, 123:609-621.
15. Librado P., Rozas J. DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. Bioinformatics 2009, 25:1451-1452.
16. Mas-Coma S. Epidemiology of Fascioliasis in human endemic areas. J. Helminthol. 2005, 79:207-216.
17. Mas-Coma S., Valero M.A., Bargues M.D. Fasciola, lymnaeids and human Fascioliasis, with a global overview on disease transmission, epidemiology, evolutionary genetics, molecular epidemiology and control. Advances in Parasitology 2009, vol. 69:41-146. Elsevier Academic Press Inc., San Diego.
18. Moll L., Gaasenbeek C.P.H., Vellema P., Borgsteede F.H.M. Resistance of Fasciola hepatica against triclabendazole in cattle and sheep in the Netherlands. Vet. Parasitol. 2000, 91:153-158.
19. Morozova E.V., Chrisanfova G.G., Arkhipov I.A., Semyenova S.K. Polymorphism of the ND1 and CO1 mitochondrial genes in populations of liver fluke Fasciola hepatica. Russ. J. Genet. 2004, 40:817-820.
20. Olaechea F., Lovera V., Larroza M., Raffo F., Cabrera R. Resistance of Fasciola hepatica against triclabendazole in cattle in Patagonia (Argentina). Vet. Parasitol. 2011, 178:364-366.
21. Overend D.J., Bowen F.L. Resistance of Fasciola hepatica to triclabendazole. Aust. Vet. J. 1995, 72:275-276.
22. Peng M., Ichinomiya M., Ohtori M., Ichikawa M., Shibahara T., Itagaki T. Molecular characterization of Fasciola hepatica, Fasciola gigantica, and aspermic Fasciola sp. in China based on nuclear and mitochondrial DNA. Parasitol. Res. 2009, 105:809-815.
23. Prugnolle F., Liu H., de Meeus T., Balloux F. Population genetics of complex life-cycle parasites: an illustration with trematodes. Int. J. Parasitol. 2005, 35:255-263.
24. Semyenova S.K., Morozova E.V., Chrisanfova G.G., Gorokhov V.V., Arkhipov I.A., Moskvin A.S., Movsessyan S.O., Ryskov A.P. Genetic differentiation in eastern European and western Asian populations of the liver fluke, Fasciola hepatica, as revealed by mitochondrial NAD1 and COX1 genes. J. Parasitol. 2006, 92:525-530.
25. Tamura K., Peterson D., Peterson N., Stecher G., Nei M., Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 2011, 28:2731-2739.
26. Walker S.M., Johnston C., Hoey E.M., Fairweather I., Borgsteede F., Gaasenbeek C., Prodohl P.A., Trudgett A. Population dynamics of the liver fluke, Fasciola hepatica: the effect of time and spatial separation on the genetic diversity of fluke populations in the Netherlands. Parasitology 2011, 138:215-223.
27. Walker S.M., Prodohl P.A., Fletcher H.L., Hanna R.E., Kantzoura V., Hoey E.M., Trudgett A. Evidence for multiple mitochondrial lineages of Fasciola hepatica (liver fluke) within infrapopulations from cattle and sheep. Parasitol. Res. 2007, 101:117-125.
28. Walker S.M., Prodöhl P.A., Hoey E.M., Fairweather I., Hanna R.E., Brennan G., Trudgett A. Substantial genetic divergence between morphologically indistinguishable populations of Fasciola suggests the possibility of cryptic speciation. Int. J. Parasitol. 2012, 42:1193-1199.
29. Winkelhagen A.J.S., Mank T., de Vries P.J., Soetekouw R. Apparent triclabendazole-resistant human Fasciola hepatica infection, the Netherlands. Emerg. Infect. Dis. 2012, 18:1028-1029.
30. Wolstenholme A.J., Fairweather I., Prichard R., von Samson-Himmelstjerna G., Sangster N.C. Drug resistance in veterinary helminths. Trends Parasitol. 2004, 20:469-476.