Predictive factors of successful microdissection testicular sperm extraction

Basic and Clinical Andrology

Volumn 23, Issue , 2013, Pages

  Bernie, Aaron M ^a   Ramasamy, Ranjith ^a   Schlegel, Peter N ^a  

^a NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

Non obstructive azoospermia; Sperm retrieval; TESE; Testicular sperm extraction

Indexed keywords

EID: 84892873234     PISSN: 20514190     EISSN: None     Source Type: Journal    
DOI: 10.1186/2051-4190-23-5     Document Type: Review

References (62)

1. Irvine DS. Epidemiology and aetiology of male infertility. Hum Reprod 1998, 13(Suppl 1):33-44. 10.1093/humrep/13.suppl_1.33, 9663768.
2. Willott GM. Frequency of azoospermia. Forensic Sci Int 1982, 20(1):9-10. 10.1016/0379-0738(82)90099-8, 7095683.
3. Schlegel PN, Li PS. Microdissection TESE: sperm retrieval in non-obstructive azoospermia. Hum Reprod Update 1998, 4(4):439. 10.1093/humupd/4.4.439, 9825858.
4. Tsujimura A. Microdissection testicular sperm extraction: prediction, outcome, and complications. Int J Urol 2007, 14(10):883-889. 10.1111/j.1442-2042.2007.01828.x, 17880285.
5. Ziaee SA, Ezzatnegad M, Nowroozi M, Jamshidian H, Abdi H, Hosseini Moghaddam SM. Prediction of successful sperm retrieval in patients with nonobstructive azoospermia. Urol J 2006, 3(2):92-96.
6. Schlegel PN. Testicular sperm extraction: microdissection improves sperm yield with minimal tissue excision. Hum Reprod 1999, 14(1):131-135. 10.1093/humrep/14.1.131, 10374109.
7. Amer M, Ateyah A, Hany R, Zohdy W. Prospective comparative study between microsurgical and conventional testicular sperm extraction in non-obstructive azoospermia: follow-up by serial ultrasound examinations. Hum Reprod 2000, 15(3):653-656. 10.1093/humrep/15.3.653, 10686214.
8. Ramasamy R, Yagan N, Schlegel PN. Structural and functional changes to the testis after conventional versus microdissection testicular sperm extraction. Urology 2005, 65(6):1190-1194. 10.1016/j.urology.2004.12.059, 15922422.
9. Carpi A, Sabanegh E, Mechanick J. Controversies in the management of nonobstructive azoospermia. Fertil Steril 2009, 91(4):963-970. 10.1016/j.fertnstert.2009.01.083, 19304289.
10. Tunc L, Kirac M, Gurocak S, Yucel A, Kupeli B, Alkibay T, Bozkirli I. Can serum Inhibin B and FSH levels, testicular histology and volume predict the outcome of testicular sperm extraction in patients with non-obstructive azoospermia?. Int Urol Nephrol 2006, 38(3-4):629-635.
11. Koscinski I, Wittemer C, Rigot JM, De Almeida M, Hermant E, Defossez A. Seminal haploid cell detection by flow cytometry in non-obstructive azoospermia: a good predictive parameter for testicular sperm extraction. Hum Reprod 2005, 20(7):1915-1920. 10.1093/humrep/deh883, 15860496.
12. Tunc L, Gurocak S, Sozen S, Tan O, Alkibay T, Bozkirli I. Is varicocele a prognostic factor for determining sperm retrieval rate before testicular sperm extraction?. Arch Androl 2005, 51(2):159-164. 10.1080/014850190884318, 15804871.
13. Vernaeve V, Staessen C, Verheyen G, Van Steirteghem A, Devroey P, Tournaye H. Can biological or clinical parameters predict testicular sperm recovery in 47, XXY Klinefelter's syndrome patients?. Hum Reprod 2004, 19(5):1135-1139. 10.1093/humrep/deh253, 15070870.
14. George JW, Dille EA, Heckert LL. Current concepts of follicle-stimulating hormone receptor gene regulation. Biol Reprod 2011, 84(1):7-17. 10.1095/biolreprod.110.085043, 20739665.
15. Mitchell V, Robin G, Boitrelle F, Massart P, Marchetti C, Marcelli F, Rigot JM. Correlation between testicular sperm extraction outcomes and clinical, endocrine and testicular histology parameters in 120 azoospermic men with normal serum FSH levels. Int J Androl 2011, 34(4):299-305.
16. Boitrelle F, Robin G, Marcelli F, Albert M, Leroy-Martin B, Dewailly D, Rigot JM, Mitchell V. A predictive score for testicular sperm extraction quality and surgical ICSI outcome in non-obstructive azoospermia: a retrospective study. Hum Reprod 2011, 26(12):3215-3221. 10.1093/humrep/der314, 21930531.
17. Zitzmann M, Nordhoff V, von Schonfeld V, Nordsiek-Mengede A, Kliesch S, Schuring AN, Luetjens CM, Kamischke A, Cooper T, Simoni M, Nieschlag E. Elevated follicle-stimulating hormone levels and the chances for azoospermic men to become fathers after retrieval of elongated spermatids from cryopreserved testicular tissue. Fertil Steril 2006, 86(2):339-347. 10.1016/j.fertnstert.2005.12.058, 16753155.
18. Aydos K, Unlu C, Demirel LC, Evirgen O, Tolunay O. The effect of pure FSH administration in non-obstructive azoospermic men on testicular sperm retrieval. Eur J Obstet Gynecol Reprod Biol 2003, 108(1):54-58. 10.1016/S0301-2115(02)00412-8, 12694971.
19. Tsujimura A, Matsumiya K, Miyagawa Y, Takao T, Fujita K, Koga M, Takeyama M, Fujioka H, Okuyama A. Prediction of successful outcome of microdissection testicular sperm extraction in men with idiopathic nonobstructive azoospermia. J Urol 2004, 172(5 Pt 1):1944-1947.
20. Huang X, Bai Q, Yan LY, Zhang QF, Geng L, Qiao J. Combination of serum inhibin B and follicle-stimulating hormone levels can not improve the diagnostic accuracy on testicular sperm extraction outcomes in Chinese non-obstructive azoospermic men. Chin Med J (Engl) 2012, 125(16):2885-2889.
21. Seo JT, Ko WJ. Predictive factors of successful testicular sperm recovery in non-obstructive azoospermia patients. Int J Androl 2001, 24(5):306-310. 10.1046/j.1365-2605.2001.00307.x, 11554989.
22. Ezeh UI, Taub NA, Moore HD, Cooke ID. Establishment of predictive variables associated with testicular sperm retrieval in men with non-obstructive azoospermia. Hum Reprod 1999, 14(4):1005-1012. 10.1093/humrep/14.4.1005, 10221234.
23. Goulis DG, Polychronou P, Mikos T, Grimbizis G, Gerou S, Pavlidou V, Papanikolaou A, Tarlatzis BC, Bontis IN, Papadimas I. Serum inhibin-B and follicle stimulating hormone as predictors of the presence of sperm in testicular fine needle aspirate in men with azoospermia. Hormones (Athens) 2008, 7(2):140-147.
24. Ramasamy R, Lin K, Gosden LV, Rosenwaks Z, Palermo GD, Schlegel PN. High serum FSH levels in men with nonobstructive azoospermia does not affect success of microdissection testicular sperm extraction. Fertil Steril 2009, 92(2):590-593. 10.1016/j.fertnstert.2008.07.1703, 18973887.
25. Jezek D, Knuth UA, Schulze W. Successful testicular sperm extraction (TESE) in spite of high serum follicle stimulating hormone and azoospermia: correlation between testicular morphology, TESE results, semen analysis and serum hormone values in 103 infertile men. Hum Reprod 1998, 13(5):1230-1234. 10.1093/humrep/13.5.1230, 9647552.
26. Hung AJ, King P, Schlegel PN. Uniform testicular maturation arrest: a unique subset of men with nonobstructive azoospermia. J Urol 2007, 178(2):608-612. discussion 612, 10.1016/j.juro.2007.03.125, 17570432.
27. Chen CS, Chu SH, Lai YM, Wang ML, Chan PR. Reconsideration of testicular biopsy and follicle-stimulating hormone measurement in the era of intracytoplasmic sperm injection for non-obstructive azoospermia?. Hum Reprod 1996, 11(10):2176-2179. 10.1093/oxfordjournals.humrep.a019072, 8943525.
28. Silber SJ, van Steirteghem A, Nagy Z, Liu J, Tournaye H, Devroey P. Normal pregnancies resulting from testicular sperm extraction and intracytoplasmic sperm injection for azoospermia due to maturation arrest. Fertil Steril 1996, 66(1):110-117.
29. Toulis KA, Iliadou PK, Venetis CA, Tsametis C, Tarlatzis BC, Papadimas I, Goulis DG. Inhibin B and anti-Mullerian hormone as markers of persistent spermatogenesis in men with non-obstructive azoospermia: a meta-analysis of diagnostic accuracy studies. Hum Reprod Update 2010, 16(6):713-724. 10.1093/humupd/dmq024, 20601364.
30. von Eckardstein S, Simoni M, Bergmann M, Weinbauer GF, Gassner P, Schepers AG, Nieschlag E. Serum inhibin B in combination with serum follicle-stimulating hormone (FSH) is a more sensitive marker than serum FSH alone for impaired spermatogenesis in men, but cannot predict the presence of sperm in testicular tissue samples. J Clin Endocrinol Metab 1999, 84(7):2496-2501. 10.1210/jc.84.7.2496, 10404826.
31. Bohring C, Schroeder-Printzen I, Weidner W, Krause W. Serum levels of inhibin B and follicle-stimulating hormone may predict successful sperm retrieval in men with azoospermia who are undergoing testicular sperm extraction. Fertil Steril 2002, 78(6):1195-1198. 10.1016/S0015-0282(02)04259-0, 12477511.
32. Ballesca JL, Balasch J, Calafell JM, Alvarez R, Fabregues F, de Osaba MJ, Ascaso C, Vanrell JA. Serum inhibin B determination is predictive of successful testicular sperm extraction in men with non-obstructive azoospermia. Hum Reprod 2000, 15(8):1734-1738. 10.1093/humrep/15.8.1734, 10920095.
33. Vernaeve V, Tournaye H, Schiettecatte J, Verheyen G, Van Steirteghem A, Devroey P. Serum inhibin B cannot predict testicular sperm retrieval in patients with non-obstructive azoospermia. Hum Reprod 2002, 17(4):971-976. 10.1093/humrep/17.4.971, 11925393.
34. Meachem SJ, Nieschlag E, Simoni M. Inhibin B in male reproduction: pathophysiology and clinical relevance. Eur J Endocrinol 2001, 145(5):561-571. 10.1530/eje.0.1450561, 11720872.
35. Schoor RA, Elhanbly S, Niederberger CS, Ross LS. The role of testicular biopsy in the modern management of male infertility. J Urol 2002, 167(1):197-200. 10.1016/S0022-5347(05)65411-0, 11743304.
36. Devroey P, Liu J, Nagy Z, Goossens A, Tournaye H, Camus M, Van Steirteghem A, Silber S. Pregnancies after testicular sperm extraction and intracytoplasmic sperm injection in non-obstructive azoospermia. Hum Reprod 1995, 10(6):1457-1460. 10.1093/HUMREP/10.6.1457, 7593514.
37. Ramasamy R, Padilla WO, Osterberg EC, Srivastava A, Reifsnyder JE, Niederberger C, Schlegel PN. A comparison of models for predicting sperm retrieval before microdissection testicular sperm extraction in men with nonobstructive azoospermia. J Urol 2013, 189(2):638-642. 10.1016/j.juro.2012.09.038, 23260551.
38. Jarow JP, Sharlip ID, Belker AM, Lipshultz LI, Sigman M, Thomas AJ, Schlegel PN, Howards SS, Nehra A, Damewood MD, et al. Best practice policies for male infertility. J Urol 2002, 167(5):2138-2144. 10.1016/S0022-5347(05)65109-9, 11956464.
39. Hopps CV, Mielnik A, Goldstein M, Palermo GD, Rosenwaks Z, Schlegel PN. Detection of sperm in men with Y chromosome microdeletions of the AZFa, AZFb and AZFc regions. Hum Reprod 2003, 18(8):1660-1665. 10.1093/humrep/deg348, 12871878.
40. Kamp C, Huellen K, Fernandes S, Sousa M, Schlegel PN, Mielnik A, Kleiman S, Yavetz H, Krause W, Kupker W, Johannisson R, Schulze W, Weidner W, Barros A, Vogt PH. High deletion frequency of the complete AZFa sequence in men with Sertoli-cell-only syndrome. Mol Hum Reprod 2001, 7(10):987-994. 10.1093/molehr/7.10.987, 11574668.
41. Stahl PJ, Masson P, Mielnik A, Marean MB, Schlegel PN, Paduch DA. A decade of experience emphasizes that testing for Y microdeletions is essential in American men with azoospermia and severe oligozoospermia. Fertil Steril 2010, 94(5):1753-1756. 10.1016/j.fertnstert.2009.09.006, 19896650.
42. Bojesen A, Juul S, Gravholt CH. Prenatal and postnatal prevalence of Klinefelter syndrome: a national registry study. J Clin Endocrinol Metab 2003, 88(2):622-626. 10.1210/jc.2002-021491, 12574191.
43. Friedler S, Raziel A, Strassburger D, Schachter M, Bern O, Ron-El R. Outcome of ICSI using fresh and cryopreserved-thawed testicular spermatozoa in patients with non-mosaic Klinefelter's syndrome. Hum Reprod 2001, 16(12):2616-2620. 10.1093/humrep/16.12.2616, 11726584.
44. Madgar I, Dor J, Weissenberg R, Raviv G, Menashe Y, Levron J. Prognostic value of the clinical and laboratory evaluation in patients with nonmosaic Klinefelter syndrome who are receiving assisted reproductive therapy. Fertil Steril 2002, 77(6):1167-1169. 10.1016/S0015-0282(02)03092-3, 12057723.
45. Ramasamy R, Ricci JA, Palermo GD, Gosden LV, Rosenwaks Z, Schlegel PN. Successful fertility treatment for Klinefelter's syndrome. J Urol 2009, 182(3):1108-1113. 10.1016/j.juro.2009.05.019, 19616796.
46. Okada H, Goda K, Yamamoto Y, Sofikitis N, Miyagawa I, Mio Y, Koshida M, Horie S. Age as a limiting factor for successful sperm retrieval in patients with nonmosaic Klinefelter's syndrome. Fertil Steril 2005, 84(6):1662-1664. 10.1016/j.fertnstert.2005.05.053, 16359961.
47. Humm KC, Sakkas D. Role of increased male age in IVF and egg donation: is sperm DNA fragmentation responsible?. Fertil Steril 2013, 99(1):30-36. 10.1016/j.fertnstert.2012.11.024, 23273987.
48. Belloc S, Cohen-Bacrie P, Benkhalifa M, Cohen-Bacrie M, De Mouzon J, Hazout A, Menezo Y. Effect of maternal and paternal age on pregnancy and miscarriage rates after intrauterine insemination. Reprod Biomed Online 2008, 17(3):392-397. 10.1016/S1472-6483(10)60223-4, 18765010.
49. Frattarelli JL, Miller KA, Miller BT, Elkind-Hirsch K, Scott RT. Male age negatively impacts embryo development and reproductive outcome in donor oocyte assisted reproductive technology cycles. Fertil Steril 2008, 90(1):97-103. 10.1016/j.fertnstert.2007.06.009, 17765235.
50. Raman JD, Schlegel PN. Testicular sperm extraction with intracytoplasmic sperm injection is successful for the treatment of nonobstructive azoospermia associated with cryptorchidism. J Urol 2003, 170(4 Pt 1):1287-1290.
51. Haimov-Kochman R, Prus D, Farchat M, Bdolah Y, Hurwitz A. Reproductive outcome of men with azoospermia due to cryptorchidism using assisted techniques. Int J Androl 2010, 33(1):e139-143. 10.1111/j.1365-2605.2009.00977.x, 19622071.
52. Negri L, Albani E, DiRocco M, Morreale G, Novara P, Levi-Setti PE. Testicular sperm extraction in azoospermic men submitted to bilateral orchidopexy. Hum Reprod 2003, 18(12):2534-2539. 10.1093/humrep/deg497, 14645168.
53. Gorelick JI, Goldstein M. Loss of fertility in men with varicocele. Fertil Steril 1993, 59(3):613-616.
54. Schlegel PN, Goldstein M. Alternate indications for varicocele repair: non-obstructive azoospermia, pain, androgen deficiency and progressive testicular dysfunction. Fertil Steril 2011, 96(6):1288-1293. 10.1016/j.fertnstert.2011.10.033, 22130099.
55. Matthews GJ, Matthews ED, Goldstein M. Induction of spermatogenesis and achievement of pregnancy after microsurgical varicocelectomy in men with azoospermia and severe oligoasthenospermia. Fertil Steril 1998, 70(1):71-75. 10.1016/S0015-0282(98)00108-3, 9660424.
56. Schlegel PN, Kaufmann J. Role of varicocelectomy in men with nonobstructive azoospermia. Fertil Steril 2004, 81(6):1585-1588. 10.1016/j.fertnstert.2003.10.036, 15193481.
57. Inci K, Hascicek M, Kara O, Dikmen AV, Gurgan T, Ergen A. Sperm retrieval and intracytoplasmic sperm injection in men with nonobstructive azoospermia, and treated and untreated varicocele. J Urol 2009, 182(4):1500-1505. 10.1016/j.juro.2009.06.028, 19683732.
58. Haydardedeoglu B, Turunc T, Kilicdag EB, Gul U, Bagis T. The effect of prior varicocelectomy in patients with nonobstructive azoospermia on intracytoplasmic sperm injection outcomes: a retrospective pilot study. Urology 2010, 75(1):83-86. 10.1016/j.urology.2009.09.023, 19913887.
59. Su LM, Palermo GD, Goldstein M, Veeck LL, Rosenwaks Z, Schlegel PN. Testicular sperm extraction with intracytoplasmic sperm injection for nonobstructive azoospermia: testicular histology can predict success of sperm retrieval. J Urol 1999, 161(1):112-116. 10.1016/S0022-5347(01)62079-2, 10037381.
60. Koga M, Tsujimura A, Takeyama M, Kiuchi H, Takao T, Miyagawa Y, Takada S, Matsumiya K, Fujioka H, Okamoto Y, Nonomura N, Okuyama A. Clinical comparison of successful and failed microdissection testicular sperm extraction in patients with nonmosaic Klinefelter syndrome. Urology 2007, 70(2):341-345. 10.1016/j.urology.2007.03.056, 17826503.
61. Tournaye H, Verheyen G, Nagy P, Ubaldi F, Goossens A, Silber S, Van Steirteghem AC, Devroey P. Are there any predictive factors for successful testicular sperm recovery in azoospermic patients?. Hum Reprod 1997, 12(1):80-86. 10.1093/humrep/12.1.80, 9043908.
62. Abdel Raheem A, Garaffa G, Rushwan N, De Luca F, Zacharakis E, Abdel Raheem T, Freeman A, Serhal P, Harper JC, Ralph D. Testicular histopathology as a predictor of a positive sperm retrieval in men with non-obstructive azoospermia. BJU Int 2013, 111(3):492-499. 10.1111/j.1464-410X.2012.11203.x, 22583840.