Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression.

Blood

Volumn 122, Issue 23, 2013, Pages 3767-3777

  Laperrousaz, Bastien ^a   Jeanpierre, Sandrine ^b   Sagorny, Karen ^b   Voeltzel, Thibault ^b   Ramas, Sophie ^b   Kaniewski, Bastien ^b   Ffrench, Martine ^b   Salesse, Stéphanie ^b   Nicolini, Franck E ^b   Maguer Satta, Véronique ^b  

^a CNRS   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BMP2 PROTEIN, HUMAN; BMP4 PROTEIN, HUMAN; BMPR1B PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN RECEPTOR 1;

BIOLOGICAL MODEL; CANCER STEM CELL; GENETICS; HUMAN; METABOLISM; MYELOID LEUKEMIA; PATHOLOGY; SIGNAL TRANSDUCTION; STEM CELL NICHE; TUMOR CELL LINE; TUMOR MICROENVIRONMENT; UPREGULATION;

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; CELL LINE, TUMOR; HUMANS; LEUKEMIA, MYELOID, CHRONIC-PHASE; MODELS, BIOLOGICAL; NEOPLASTIC STEM CELLS; SIGNAL TRANSDUCTION; STEM CELL NICHE; TUMOR MICROENVIRONMENT; UP-REGULATION;

EID: 84892854518     PISSN: None     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-05-501460     Document Type: Article

References (0)