Diagnostic contribution of 18F-FDG-PET/CT in fever of unknown origin

International Journal of Infectious Diseases

Volumn 19, Issue 1, 2014, Pages 53-58

  Tokmak, Handan ^a   Ergonul, Onder ^b   Demirkol, Onur ^b   Cetiner, Mustafa ^b   Ferhanoglu, Burhan ^b  

^a AMERICAN HOSPITAL   (Turkey)

^b KOÇ UNIVERSITY   (Turkey)

Author keywords

18F FDG PET CT; Fever of unknown origin (FUO); Imaging follow up of FUO; Inflammatory non infectious disease; Vasculitis

Indexed keywords

FLUORODEOXYGLUCOSE F 18; RADIOPHARMACEUTICAL AGENT;

ADOLESCENT; ADULT; AGED; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; BIOCHEMISTRY; CLINICAL ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CORTICOSTEROID THERAPY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DRUG UPTAKE; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; INFECTION; INFLAMMATION; MALE; MEDIASTINUM LYMPH NODE; MIDDLE AGED; OBSERVATIONAL STUDY; PET-CT SCANNER; PYREXIA IDIOPATHICA; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; TEMPORAL ARTERITIS; VERY ELDERLY; YOUNG ADULT; DIAGNOSTIC USE; DIFFERENTIAL DIAGNOSIS; EVALUATION STUDY; FEVER OF UNKNOWN ORIGIN; POSITRON EMISSION TOMOGRAPHY; PROCEDURES; SCINTISCANNING; STANDARDS; DIAGNOSTIC PROCEDURE; MICROBIOLOGICAL EXAMINATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DIAGNOSIS, DIFFERENTIAL; FEMALE; FEVER OF UNKNOWN ORIGIN; FLUORODEOXYGLUCOSE F18; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; YOUNG ADULT;

EID: 84892837958     PISSN: 12019712     EISSN: 18783511     Source Type: Journal    
DOI: 10.1016/j.ijid.2013.10.009     Document Type: Article

References (30)

1. De Winter F., Vogelaers D., Gemmel F., Dierckx R.A. Promising role of 18-F-fluoro-deoxyglucose positron emission tomography in clinical infectious diseases. Eur J Clin Microbiol Infect Dis 2002, 21:247-257.
2. Balink H., Collins J., Bruyn G.A., Gemmel F. F-18 FDG PET/CT in the diagnosis of fever of unknown origin. Clin Nucl Med 2009, 34:862-870.
3. Ferda J., Ferdová E., Záhlava J., Matejovic M., Kreuzberg B. Fever of unknown origin: a value of (18)F-FDG-PET/CT with integrated full diagnostic isotropic CT imaging. Eur J Radiol 2010, 73:518-525.
4. Federici L., Blondet C., Imperiale A., Sibilia J., Pasquali J.L., Pflumio F., et al. Value of (18)F-FDG-PET/CT in patients with fever of unknown origin and unexplained prolonged inflammatory syndrome: a single centre analysis experience. Int J Clin Pract 2010, 64:55-60.
5. Keidar Z., Gurman-Balbir A., Gaitini D., Israel O. Fever of unknown origin: the role of 18F-FDG PET/CT. J Nucl Med 2008, 49:1980.
6. Bleeker-Rovers C.P., de Kleijn E.M., Corstens F.H., van der Meer J.W., Oyen W.J. Clinical value of FDG PET in patients with fever of unknown origin and patients suspected of focal infection or inflammation. Eur J Nucl Med Mol Imaging 2004, 31:29-37.
7. Bleeker-Rovers C.P., Vos F.J., Mudde A.H., Dofferhoff A.S., de Geus-Oei L.F., Rijnders A.J., et al. A prospective multi-centre study of the value of FDG-PET as part of a structured diagnostic protocol in patients with fever of unknown origin. Eur J Nucl Med Mol Imaging 2007, 34:694-703.
8. Gaeta G.B., Fusco F.M., Nardiello S. Fever of unknown origin: a systematic review of the literature for 1995-2004. Nucl Med Commun 2006, 27:205-211.
9. Kumar R., Basu S., Torigian D., Anand V., Zhuang H., Alavi A. Role of modern imaging techniques for diagnosis of infection in the era of 18F-fluorodeoxyglucose positron emission tomography. Clin Microbiol Rev 2008, 21:209-224.
10. Knockaert D.C., Vanderschueren S., Blockmans D. Fever of unknown origin in adults: 40 years on. J Intern Med 2003, 253:263-275.
11. Kim Y.J., Kim S.I., Hong K.W., Kang M.W. Diagnostic value of 18F-FDG PET/CT in patients with fever of unknown origin. Intern Med J 2012, 42:834-841.
12. Qiu L., Chen Y. The role of 18F-FDG PET or PET/CT in the detection of fever of unknown origin. Eur J Radiol 2012, 81:3524-3533.
13. Pelosi E., Skanjeti A., Penna D., Arena V. Role of integrated PET/CT with [18F]-FDG in the management of patients with fever of unknown origin: a single-centre experience. Radiol Med 2011, 116:809-829.
14. Blockmans D., Knockaer D., Maes A., De Caestecker J., Stroobants S., Bobbaers H., et al. Clinical value of [18F] fluoro-deoxyglucose positron emission tomography for patients with fever of unknown origin. Clin Infect Dis 2001, 32:191-196.
15. Jaruskova M., Belohlavek O. Role of FDG-PET and PET/CT in the diagnosis of prolonged febrile states. Eur J Nucl Med Mol Imaging 2006, 33:913-918.
16. Zenone T. Fever of unknown origin in adults: evaluation of 144 cases in a non-university hospital. Scand J Infect Dis 2006, 38:632-640.
17. Ergonul O., Willke A., Azap A., Tekeli E. Revised definition of "Fever of Unknown Origin": limitations and opportunities. J Infect 2005, 50:1-5.
18. Kjaer A., Lebech A.M., Eigtved A., Højgaard L. Fever of unknown origin: prospective comparison of diagnostic value of 18F-FDG PET and 111In-granulocyte scintigraphy. Eur J Nucl Med Mol Imaging 2004, 31:622-628.
19. Meller J., Altenvoerde G., Munzel U., Jauho A., Behe M., Gratz S., et al. Fever of unknown origin: prospective comparison of [18F]FDG imaging with a double-head coincidence camera and gallium-67 citrate SPET. Eur J Nucl Med 2000, 27:1617-1625.
20. Meller J., Sahlmann C.O., Scheel A.K. F-FDG PET and PET/CT in fever of unknown origin. J Nucl Med 2007, 48:35-45.
21. Meller J., Becker W. Nuclear medicine diagnosis of patients with fever of unknown origin (FUO). Nuklearmedizin 2001, 40:59-70.
22. Gratz S., Kemke B., Kaiser W., Hahn U., Erdtmann B., Schilling M., et al. Diagnosis of fever of unknown origin (FUO)-positron emission tomography/computed tomography (PET-CT). Dtsch Med Wochenschr 2009, 134:2120-2124.
23. Krem M.M., Pan L., Blinder M.A. (18)F-FDG-PET-facilitated diagnosis of lymphoma presenting with fever of unknown origin and cold agglutination. Leuk Lymphoma 2007, 48:619-622.
24. Meller J., Sahlmann C.O., Gürocak O., Liersch T., Meller B. FDG-PET in patients with fever of unknown origin: the importance of diagnosing large vessel vasculitis. Q J Nucl Med Mol Imaging 2009, 53:51-63.
25. Bleeker-Rovers C.P., Bredie S.J., van der Meer J.W., Corstens F.H., Oyen W.J. F-18-fluorodeoxyglucose positron emission tomography in diagnosis and follow-up of patients with different types of vasculitis. Neth J Med 2003, 61:323-329.
26. Federici L., Blondet C., Imperiale A., Sibilia J., Pasquali J.L., Pflumio F., et al. Value of F-FDG-PET/CT in patients with fever of unknown origin and unexplained prolonged inflammatory syndrome: a single centre analysis experience. Int J Clin Pract 2010, 64:55-60.
27. Umekita K., Takajo I., Miyauchi S., Tsurumura K., Ueno S., Kusumoto N., et al. [18F] fluorodeoxyglucose positron emission tomography is a useful tool to diagnose the early stage of Takayasu's arteritis and to evaluate the activity of the disease. Mod Rheumatol 2006, 16:243-250.
28. Pedersen T., Roed C., Knudsen L., Loft A., Skinhoj P., Nielsen S.D. Fever of unknown origin: a retrospective study of 52 cases with evaluation of the diagnostic utility of FDG-PET/CT. Scand J Infect Dis 2012, 44:18-23.
29. Crouzet J., Boudousq V., Lechiche C., Pouget J.P., Kotzki P.O., Collombier L., et al. Place of (18)F-FDG-PET with computed tomography in the diagnostic algorithm of patients with fever of unknown origin. Eur J Clin Microbiol Infect Dis 2012, 31:1727-1733.
30. Becerra Nakayo E.M., García Vicente A.M., Soriano Castrejón A.M., Mendoza Narváez J.A., Talavera Rubio M.P., Poblete García V.M. Analysis of cost-effectiveness in the diagnosis of fever of unknown origin and the role of 18F-FDG PET-CT: a proposal of diagnostic algorithm. Rev Esp Med Nucl Imagen Mol 2012, 31:178-186.