Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells

FEBS Letters

Volumn 588, Issue 3, 2014, Pages 472-481

  Pal, Rituraj ^a   Monroe, Tanner O ^a   Palmieri, Michela ^a   Sardiello, Marco ^a   Rodney, George G ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Impaired UPS; NADPH oxidase; Neurodegenerative disease; Nox; Rac1; Rotenone

Indexed keywords

CALCIUM; GLUTATHIONE; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROTENONE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROTOXICITY; NITROSATIVE STRESS; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION; RESPIRATORY CHAIN, OXIDATIVE PHOSPHORYLATION AND CELLULAR ENERGETICS; UBIQUITIN PROTEASOME SYSTEM;

IMPAIRED UPS; NADPH OXIDASE; NEURODEGENERATIVE DISEASE; NOX; RAC1; ROTENONE;

APOPTOSIS; CELL LINE, TUMOR; CYTOSOL; ENDOPLASMIC RETICULUM STRESS; HUMANS; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; NEURODEGENERATIVE DISEASES; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; ROTENONE; SIGNAL TRANSDUCTION;

EID: 84892820469     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.12.011     Document Type: Article

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