-
1
-
-
67649579669
-
Updated clinical classification of pulmonary hypertension
-
Simonneau, G., Robbins, I.M., Beghetti, M. et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2009, 54(1 Suppl): S43-54.
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.1 SUPPL.
-
-
Simonneau, G.1
Robbins, I.M.2
Beghetti, M.3
-
2
-
-
77955953602
-
Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension
-
Humbert, M., Sitbon, O., Yaici, A. et al. Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension. Eur Respir J 2010, 36(3): 549-55.
-
(2010)
Eur Respir J
, vol.36
, Issue.3
, pp. 549-555
-
-
Humbert, M.1
Sitbon, O.2
Yaici, A.3
-
3
-
-
84883331015
-
Therapies for pulmonary arterial hypertension: Where are we today, where do we go tomorrow?
-
Seferian, A., Simonneau, G. Therapies for pulmonary arterial hypertension: where are we today, where do we go tomorrow? Eur Respir Rev 2013, 22(129): 217-26.
-
(2013)
Eur Respir Rev
, vol.22
, Issue.129
, pp. 217-226
-
-
Seferian, A.1
Simonneau, G.2
-
4
-
-
84885316129
-
Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: Results from the COMPERA registry
-
Hoeper, M.M., Huscher, D., Ghofrani, H.A. et al. Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: Results from the COMPERA registry. Int J Cardiol 2013, 168(2): 871-80.
-
(2013)
Int J Cardiol
, vol.168
, Issue.2
, pp. 871-880
-
-
Hoeper, M.M.1
Huscher, D.2
Ghofrani, H.A.3
-
5
-
-
84878576691
-
Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension
-
Germain, M., Eyries, M., Montani, D. et al. Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension. Nat Genet 2013, 45(5): 518-21.
-
(2013)
Nat Genet
, vol.45
, Issue.5
, pp. 518-521
-
-
Germain, M.1
Eyries, M.2
Montani, D.3
-
6
-
-
0035891626
-
Chronic thromboembolic pulmonary hypertension
-
Fedullo, P.F., Auger, W.R., Kerr, K.M., Rubin, L.J. Chronic thromboembolic pulmonary hypertension. N Engl J Med 2001, 345(20): 1465-72.
-
(2001)
N Engl J Med
, vol.345
, Issue.20
, pp. 1465-1472
-
-
Fedullo, P.F.1
Auger, W.R.2
Kerr, K.M.3
Rubin, L.J.4
-
7
-
-
77649214587
-
Surgical and post-operative treatment of chronic thromboembolic pulmonary hypertension
-
Mayer, E. Surgical and post-operative treatment of chronic thromboembolic pulmonary hypertension. Eur Respir Rev 2010, 19(115): 64-7.
-
(2010)
Eur Respir Rev
, vol.19
, Issue.115
, pp. 64-67
-
-
Mayer, E.1
-
8
-
-
34247530270
-
Predictors of outcome in chronic thromboembolic pulmonary hypertension
-
Bonderman, D., Skoro-Sajer, N., Jakowitsch, J. et al. Predictors of outcome in chronic thromboembolic pulmonary hypertension. Circulation 2007, 115(16): 2153-8.
-
(2007)
Circulation
, vol.115
, Issue.16
, pp. 2153-2158
-
-
Bonderman, D.1
Skoro-Sajer, N.2
Jakowitsch, J.3
-
9
-
-
33748765846
-
Pulmonary microvascular disease in chronic thromboembolic pulmonary hypertension
-
Galie, N., Kim, N.H. Pulmonary microvascular disease in chronic thromboembolic pulmonary hypertension. Proc Am Thorac Soc 2006, 3(7): 571-6.
-
(2006)
Proc Am Thorac Soc
, vol.3
, Issue.7
, pp. 571-576
-
-
Galie, N.1
Kim, N.H.2
-
10
-
-
84880721470
-
Riociguat for the treatment of pulmonary arterial hypertension
-
Ghofrani, H.A., Galie, N., Grimminger, F. et al. Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med 2013, 369(4): 330-40.
-
(2013)
N Engl J Med
, vol.369
, Issue.4
, pp. 330-340
-
-
Ghofrani, H.A.1
Galie, N.2
Grimminger, F.3
-
11
-
-
84880732460
-
Riociguat for the treatment of chronic thromboembolic pulmonary hypertension
-
Ghofrani, H.A., D'Armini, A.M., Grimminger, F. et al. Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. N Engl J Med 2013, 369(4): 319-29.
-
(2013)
N Engl J Med
, vol.369
, Issue.4
, pp. 319-329
-
-
Ghofrani, H.A.1
D'Armini, A.M.2
Grimminger, F.3
-
12
-
-
15944424291
-
Chronically elevated endothelin levels reduce pulmonary vascular reactivity to nitric oxide
-
Migneault, A., Sauvageau, S., Villeneuve, L., Thorin, E., Fournier, A., Leblanc, N., Dupuis, J. Chronically elevated endothelin levels reduce pulmonary vascular reactivity to nitric oxide. Am J Respir Crit Care Med 2005, 171(5): 506-13.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, Issue.5
, pp. 506-513
-
-
Migneault, A.1
Sauvageau, S.2
Villeneuve, L.3
Thorin, E.4
Fournier, A.5
Leblanc, N.6
Dupuis, J.7
-
13
-
-
0033898202
-
Pulmonary fibrosis and chronic lung inflammation in ET-1 transgenic mice
-
Hocher, B., Schwarz, A., Fagan, K.A. et al. Pulmonary fibrosis and chronic lung inflammation in ET-1 transgenic mice. Am J Respir Cell Mol Biol 2000, 23(1): 19-26.
-
(2000)
Am J Respir Cell Mol Biol
, vol.23
, Issue.1
, pp. 19-26
-
-
Hocher, B.1
Schwarz, A.2
Fagan, K.A.3
-
14
-
-
40649084619
-
Endothelin receptor antagonists in pulmonary arterial hypertension
-
Dupuis, J., Hoeper, M.M. Endothelin receptor antagonists in pulmonary arterial hypertension. Eur Respir J 2008, 31(2): 407-15.
-
(2008)
Eur Respir J
, vol.31
, Issue.2
, pp. 407-415
-
-
Dupuis, J.1
Hoeper, M.M.2
-
15
-
-
73749086478
-
A review of prostaglandin analogs in the management of patients with pulmonary arterial hypertension
-
Mubarak, K.K. A review of prostaglandin analogs in the management of patients with pulmonary arterial hypertension. Respir Med 2010, 104(1): 9-21.
-
(2010)
Respir Med
, vol.104
, Issue.1
, pp. 9-21
-
-
Mubarak, K.K.1
-
16
-
-
0037006966
-
Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension
-
Ghofrani, H.A., Wiedemann, R., Rose, F. et al. Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med 2002, 136(7): 515-22.
-
(2002)
Ann Intern Med
, vol.136
, Issue.7
, pp. 515-522
-
-
Ghofrani, H.A.1
Wiedemann, R.2
Rose, F.3
-
17
-
-
0037086133
-
Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: A double-blind, randomized, placebo-controlled trial
-
Simonneau, G., Barst, R.J., Galie, N. et al. Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med 2002, 165(6): 800-4.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, Issue.6
, pp. 800-804
-
-
Simonneau, G.1
Barst, R.J.2
Galie, N.3
-
18
-
-
84868212644
-
Safety and efficacy of transition from systemic prostanoids to inhaled treprostinil in pulmonary arterial hypertension
-
de Jesus Perez, V.A., Rosenzweig, E., Rubin, L.J. et al. Safety and efficacy of transition from systemic prostanoids to inhaled treprostinil in pulmonary arterial hypertension. Am J Cardiol 2012, 110(10): 1546-50.
-
(2012)
Am J Cardiol
, vol.110
, Issue.10
, pp. 1546-1550
-
-
De Jesus Perez, V.A.1
Rosenzweig, E.2
Rubin, L.J.3
-
19
-
-
0141482069
-
Immediate and long-term hemodynamic and clinical effects of sildenafil in patients with pulmonary arterial hypertension receiving vasodilator therapy
-
Bhatia, S., Frantz, R.P., Severson, C.J., Durst, L.A., McGoon, M.D. Immediate and long-term hemodynamic and clinical effects of sildenafil in patients with pulmonary arterial hypertension receiving vasodilator therapy. Mayo Clin Proc 2003, 78(10): 1207-13.
-
(2003)
Mayo Clin Proc
, vol.78
, Issue.10
, pp. 1207-1213
-
-
Bhatia, S.1
Frantz, R.P.2
Severson, C.J.3
Durst, L.A.4
McGoon, M.D.5
-
20
-
-
0035952993
-
NO-independent stimulators of soluble guanylate cyclase
-
Straub, A., Stasch, J.P., Alonso-Alija, C., Benet-Buchholz, J., Ducke, B., Feurer, A., Furstner, C. NO-independent stimulators of soluble guanylate cyclase. Bioorg Med Chem Lett 2001, 11(6): 781-4.
-
(2001)
Bioorg Med Chem Lett
, vol.11
, Issue.6
, pp. 781-784
-
-
Straub, A.1
Stasch, J.P.2
Alonso-Alija, C.3
Benet-Buchholz, J.4
Ducke, B.5
Feurer, A.6
Furstner, C.7
-
21
-
-
67651094166
-
Discovery of riociguat (BAY 63-2521): A potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension
-
Mittendorf, J., Weigand, S., Alonso-Alija, C. et al. Discovery of riociguat (BAY 63-2521): a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension. ChemMedChem 2009, 4(5): 853-65.
-
(2009)
ChemMedChem
, vol.4
, Issue.5
, pp. 853-865
-
-
Mittendorf, J.1
Weigand, S.2
Alonso-Alija, C.3
-
22
-
-
0028109332
-
YC-1, a novel activator of platelet guanylate cyclase
-
Ko, F.N., Wu, C.C., Kuo, S.C., Lee, F.Y., Teng, C.M. YC-1, a novel activator of platelet guanylate cyclase. Blood 1994, 84(12): 4226-33.
-
(1994)
Blood
, vol.84
, Issue.12
, pp. 4226-4233
-
-
Ko, F.N.1
Wu, C.C.2
Kuo, S.C.3
Lee, F.Y.4
Teng, C.M.5
-
23
-
-
53849089139
-
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension
-
Schermuly, R.T., Stasch, J.P., Pullamsetti, S.S. et al. Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension. Eur Respir J 2008, 32(4): 881-91.
-
(2008)
Eur Respir J
, vol.32
, Issue.4
, pp. 881-891
-
-
Schermuly, R.T.1
Stasch, J.P.2
Pullamsetti, S.S.3
-
24
-
-
79960599350
-
Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats
-
Geschka, S., Kretschmer, A., Sharkovska, Y. et al. Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats. PLoS One 2011, 6(7): e21853.
-
(2011)
PLoS One
, vol.6
, Issue.7
-
-
Geschka, S.1
Kretschmer, A.2
Sharkovska, Y.3
-
25
-
-
84865065450
-
The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats
-
Lang, M., Kojonazarov, B., Tian, X. et al. The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats. PLoS One 2012, 7(8): e43433.
-
(2012)
PLoS One
, vol.7
, Issue.8
-
-
Lang, M.1
Kojonazarov, B.2
Tian, X.3
-
26
-
-
47549110195
-
Single-dose pharmacokinetics, pharmacodynamics, tolerability, and safety of the soluble guanylate cyclase stimulator BAY 63-2521: An ascending-dose study in healthy male volunteers
-
Frey, R., Muck, W., Unger, S., Artmeier-Brandt, U., Weimann, G., Wensing, G. Single-dose pharmacokinetics, pharmacodynamics, tolerability, and safety of the soluble guanylate cyclase stimulator BAY 63-2521: an ascending-dose study in healthy male volunteers. J Clin Pharmacol 2008, 48(8): 926-34.
-
(2008)
J Clin Pharmacol
, vol.48
, Issue.8
, pp. 926-934
-
-
Frey, R.1
Muck, W.2
Unger, S.3
Artmeier-Brandt, U.4
Weimann, G.5
Wensing, G.6
-
27
-
-
84892757300
-
-
Accessed November 15, 2013
-
Effect of Riociguat on Bone Metabolism. http://clinicaltrials.gov/ct2/ show/NCT00855660?id=NCT00855660&rank=1. Accessed November 15, 2013.
-
Effect of Riociguat on Bone Metabolism
-
-
-
29
-
-
63849256355
-
First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension
-
Grimminger, F., Weimann, G., Frey, R. et al. First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension. Eur Respir J 2009, 33(4): 785-92.
-
(2009)
Eur Respir J
, vol.33
, Issue.4
, pp. 785-792
-
-
Grimminger, F.1
Weimann, G.2
Frey, R.3
-
30
-
-
49449102583
-
Long-term use of sildenafil in inoperable chronic thromboembolic pulmonary hypertension
-
Suntharalingam, J., Treacy, C.M., Doughty, N.J. et al. Long-term use of sildenafil in inoperable chronic thromboembolic pulmonary hypertension. Chest 2008, 134(2): 229-36.
-
(2008)
Chest
, vol.134
, Issue.2
, pp. 229-236
-
-
Suntharalingam, J.1
Treacy, C.M.2
Doughty, N.J.3
-
31
-
-
57449103127
-
Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial
-
Jais, X., D'Armini, A.M., Jansa, P. et al. Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial. J Am Coll Cardiol 2008, 52(25): 2127-34.
-
(2008)
J Am Coll Cardiol
, vol.52
, Issue.25
, pp. 2127-2134
-
-
Jais, X.1
D'Armini, A.M.2
Jansa, P.3
-
32
-
-
79952638658
-
Riociguat (BAY 63-2521) and warfarin: A pharmacodynamic and pharmacokinetic interaction study
-
Frey, R., Muck, W., Kirschbaum, N., Kratzschmar, J., Weimann, G., Wensing, G. Riociguat (BAY 63-2521) and warfarin: a pharmacodynamic and pharmacokinetic interaction study. J Clin Pharmacol 2011, 51(7): 1051-60.
-
(2011)
J Clin Pharmacol
, vol.51
, Issue.7
, pp. 1051-1060
-
-
Frey, R.1
Muck, W.2
Kirschbaum, N.3
Kratzschmar, J.4
Weimann, G.5
Wensing, G.6
-
33
-
-
0035845634
-
Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension
-
Wilkens, H., Guth, A., Konig, J. et al. Effect of inhaled iloprost plus oral sildenafil in patients with primary pulmonary hypertension. Circulation 2001, 104(11): 1218-22.
-
(2001)
Circulation
, vol.104
, Issue.11
, pp. 1218-1222
-
-
Wilkens, H.1
Guth, A.2
Konig, J.3
-
34
-
-
0037389118
-
Long-term treatment with oral sildenafil in addition to continuous IV epoprostenol in patients with pulmonary arterial hypertension
-
Stiebellehner, L., Petkov, V., Vonbank, K., Funk, G., Schenk, P., Ziesche, R., Block, L.H. Long-term treatment with oral sildenafil in addition to continuous IV epoprostenol in patients with pulmonary arterial hypertension. Chest 2003, 123(4): 1293-5.
-
(2003)
Chest
, vol.123
, Issue.4
, pp. 1293-1295
-
-
Stiebellehner, L.1
Petkov, V.2
Vonbank, K.3
Funk, G.4
Schenk, P.5
Ziesche, R.6
Block, L.H.7
-
35
-
-
0037868048
-
Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension
-
Ghofrani, H.A., Rose, F., Schermuly, R.T. et al. Oral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertension. J Am Coll Cardiol 2003, 42(1): 158-64.
-
(2003)
J Am Coll Cardiol
, vol.42
, Issue.1
, pp. 158-164
-
-
Ghofrani, H.A.1
Rose, F.2
Schermuly, R.T.3
-
36
-
-
10444246635
-
Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension
-
Hoeper, M.M., Faulenbach, C., Golpon, H., Winkler, J., Welte, T., Niedermeyer, J. Combination therapy with bosentan and sildenafil in idiopathic pulmonary arterial hypertension. Eur Respir J 2004, 24(6): 1007-10.
-
(2004)
Eur Respir J
, vol.24
, Issue.6
, pp. 1007-1010
-
-
Hoeper, M.M.1
Faulenbach, C.2
Golpon, H.3
Winkler, J.4
Welte, T.5
Niedermeyer, J.6
-
37
-
-
15744382057
-
Addition of oral sildenafil to beraprost is a safe and effective therapeutic option for patients with pulmonary hypertension
-
Ikeda, D., Tsujino, I., Ohira, H. et al. Addition of oral sildenafil to beraprost is a safe and effective therapeutic option for patients with pulmonary hypertension. J Cardiovasc Pharmacol 2005, 45(4): 286-9.
-
(2005)
J Cardiovasc Pharmacol
, vol.45
, Issue.4
, pp. 286-289
-
-
Ikeda, D.1
Tsujino, I.2
Ohira, H.3
-
38
-
-
27744504402
-
Goal-oriented treatment and combination therapy for pulmonary arterial hypertension
-
Hoeper, M.M., Markevych, I., Spiekerkoetter, E., Welte, T., Niedermeyer, J. Goal-oriented treatment and combination therapy for pulmonary arterial hypertension. Eur Respir J 2005, 26(5): 858-63.
-
(2005)
Eur Respir J
, vol.26
, Issue.5
, pp. 858-863
-
-
Hoeper, M.M.1
Markevych, I.2
Spiekerkoetter, E.3
Welte, T.4
Niedermeyer, J.5
-
39
-
-
33644821677
-
Successful switch from long-term intravenous iloprost to non-invasive combination therapy in idiopathic pulmonary arterial hypertension
-
Halank, M., Kolditz, M., Opitz, C., Hoeffken, G., Ewert, R. Successful switch from long-term intravenous iloprost to non-invasive combination therapy in idiopathic pulmonary arterial hypertension. Wien Klin Wochenschr 2006, 118(1-2): 54-9.
-
(2006)
Wien Klin Wochenschr
, vol.118
, Issue.1-2
, pp. 54-59
-
-
Halank, M.1
Kolditz, M.2
Opitz, C.3
Hoeffken, G.4
Ewert, R.5
-
40
-
-
54549125950
-
Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: A randomized trial
-
Simonneau, G., Rubin, L.J., Galie, N. et al. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med 2008, 149(8): 521-30.
-
(2008)
Ann Intern Med
, vol.149
, Issue.8
, pp. 521-530
-
-
Simonneau, G.1
Rubin, L.J.2
Galie, N.3
-
41
-
-
21744438514
-
Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension
-
Paul, G.A., Gibbs, J.S., Boobis, A.R., Abbas, A., Wilkins, M.R. Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension. Br J Clin Pharmacol 2005, 60(1): 107-12.
-
(2005)
Br J Clin Pharmacol
, vol.60
, Issue.1
, pp. 107-112
-
-
Paul, G.A.1
Gibbs, J.S.2
Boobis, A.R.3
Abbas, A.4
Wilkins, M.R.5
|