The interrelationship between ligand binding and thermal unfolding of the folate binding protein. the role of self-association and pH

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1844, Issue 3, 2014, Pages 512-519

  Holm, Jan ^a   Babol, Linnea N ^b   Markova, Natalia ^b   Lawaetz, Anders J ^c   Hansen, Steen I ^a  

^a HILLERØD HOSPITAL   (Denmark)

^b GE Healthcare Life Sciences   (Sweden)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Differential scanning calorimetry; Dynamic light scattering; Fluorescence changes associated with irreversible thermal unfolding; Folate binding protein (soluble folate receptor); Temperature dependent self association; Thermoresistant holo protein

Indexed keywords

FOLATE BINDING PROTEIN; POLYMER;

ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DYNAMIC LIGHT SCATTERING; LIGAND BINDING; LIGHT SCATTERING; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN UNFOLDING; TEMPERATURE; THERMOSTABILITY; ULTRACENTRIFUGATION;

DIFFERENTIAL SCANNING CALORIMETRY; DYNAMIC LIGHT SCATTERING; FLUORESCENCE CHANGES ASSOCIATED WITH IRREVERSIBLE THERMAL UNFOLDING; FOLATE BINDING PROTEIN (SOLUBLE FOLATE RECEPTOR); TEMPERATURE-DEPENDENT SELF-ASSOCIATION; THERMORESISTANT HOLO-PROTEIN;

ANIMALS; CALORIMETRY, DIFFERENTIAL SCANNING; CARRIER PROTEINS; CATTLE; FOLIC ACID; HOT TEMPERATURE; HYDROGEN-ION CONCENTRATION; LIGANDS; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN UNFOLDING; SPECTROMETRY, FLUORESCENCE;

EID: 84892730066     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2013.12.009     Document Type: Article

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