Development of a formula for estimating plasma free cortisol concentration from a measured total cortisol concentration when elastase-cleaved and intact corticosteroid binding globulin coexist

Journal of Steroid Biochemistry and Molecular Biology

Volumn 141, Issue , 2014, Pages 16-25

  Nguyen, Phuong T T ^a   Lewis, John G ^b   Sneyd, James ^c   Lee, Rita S F ^a   Torpy, David J ^d   Shorten, Paul R ^a,c  

^a RUAKURA RESEARCH CENTRE   (New Zealand)

^b CANTERBURY HEALTH LABORATORIES   (New Zealand)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d ROYAL ADELAIDE HOSPITAL   (Australia)

Author keywords

Binding affinity; Corticosteroid binding proteins; Cortisol partitioning; Equilibrium model

Indexed keywords

ALBUMIN; ELASTASE; HYDROCORTISONE; TRANSCORTIN;

ARTICLE; BINDING AFFINITY; CHEMICAL MODEL; CLEARANCE; COMPARTMENT MODEL; HUMAN; IN VIVO STUDY; INFLAMMATION; NEUTROPHIL; PLASMA; SEPTIC SHOCK; VALIDATION PROCESS;

BINDING AFFINITY; CORTICOSTEROID-BINDING PROTEINS; CORTISOL PARTITIONING; EQUILIBRIUM MODEL;

ALGORITHMS; BLOOD CHEMICAL ANALYSIS; HUMANS; HYDROCORTISONE; MODELS, BIOLOGICAL; PANCREATIC ELASTASE; PROTEIN BINDING; PROTEOLYSIS; TRANSCORTIN;

EID: 84892729151     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2013.12.015     Document Type: Article

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