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Volumn 20, Issue 1, 2014, Pages 84-93

Pasireotide and mifepristone: New options in the medical management of cushing's disease

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; INCRETIN; MIFEPRISTONE; PASIREOTIDE; HYDROCORTISONE RECEPTOR; SOMATOSTATIN;

EID: 84892725887     PISSN: 1530891X     EISSN: 19342403     Source Type: Journal    
DOI: 10.4158/EP13127.RA     Document Type: Review
Times cited : (7)

References (41)
  • 1
    • 0028339489 scopus 로고
    • Morbidity and mortality in Cushing's disease: An epidemiological approach
    • Etxabe J, Vazquez JA. Morbidity and mortality in Cushing's disease: an epidemiological approach. Clin Endocrinol (Oxf). 1994;40:479-484.
    • (1994) Clin Endocrinol (Oxf) , vol.40 , pp. 479-484
    • Etxabe, J.1    Vazquez, J.A.2
  • 2
    • 47549104969 scopus 로고    scopus 로고
    • Treatment of adrenocorticotropin-dependent Cushing's syndrome: A consensus statement
    • Biller BMK, Grossman AB, Stewart PM, et al. Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement. J Clin Endocrinol Metab. 2008;93:2454-2462.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2454-2462
    • Bmk, B.1    Grossman, A.B.2    Stewart, P.M.3
  • 5
    • 0034114436 scopus 로고    scopus 로고
    • Treatment of pituitary-dependent Cushing's syndrome: Long-term results of unilateral adrenalectomy followed by external pituitary irradiation compared to transsphenoidal pituitary surgery
    • Nagesser SK, van Seters AP, Kievit J, et al. Treatment of pituitary-dependent Cushing's syndrome: long-term results of unilateral adrenalectomy followed by external pituitary irradiation compared to transsphenoidal pituitary surgery. Clin Endocrinol (Oxf). 2000;52:427-435.
    • (2000) Clin Endocrinol (Oxf) , vol.52 , pp. 427-435
    • Nagesser, S.K.1    Van Seters, A.P.2    Kievit, J.3
  • 6
    • 38449091343 scopus 로고    scopus 로고
    • Transsphenoidal surgery for Cushing's disease: A review of success rates, remission predictors, management of failed surgery, and Nelson's Syndrome
    • Kelly DF. Transsphenoidal surgery for Cushing's disease: a review of success rates, remission predictors, management of failed surgery, and Nelson's Syndrome. Neurosurg Focus. 2007;23:E5.
    • (2007) Neurosurg Focus , vol.23
    • Kelly, D.F.1
  • 7
    • 27744474039 scopus 로고    scopus 로고
    • Long-term remission rates after pituitary surgery for Cushing's disease: The need for long-term surveillance
    • Atkinson AB, Kennedy A, Wiggam MI, McCance DR, Sheridan B. Long-term remission rates after pituitary surgery for Cushing's disease: the need for long-term surveillance. Clin Endocrinol (Oxf). 2005;63:549-559.
    • (2005) Clin Endocrinol (Oxf) , vol.63 , pp. 549-559
    • Atkinson, A.B.1    Kennedy, A.2    Wiggam, M.I.3    McCance, D.R.4    Sheridan, B.5
  • 9
    • 84867399092 scopus 로고    scopus 로고
    • Medical management of cushing's disease: What is the future?
    • Fleseriu M, Petersenn S. Medical management of Cushing's disease: what is the future? Pituitary. 2012;15:330-341.
    • (2012) Pituitary , vol.15 , pp. 330-341
    • Fleseriu, M.1    Petersenn, S.2
  • 11
    • 0029946097 scopus 로고    scopus 로고
    • Mifepristone: Treatment of Cushing's syndrome
    • Sartor O, Cutler GB Jr. Mifepristone: treatment of Cushing's syndrome. Clin Obstet Gynecol. 1996;39: 506-510.
    • (1996) Clin Obstet Gynecol , vol.39 , pp. 506-510
    • Sartor, O.1    Cutler Jr., G.B.2
  • 12
    • 36549032804 scopus 로고    scopus 로고
    • Mifepristone (RU 486) in Cushing's syndrome
    • Johanssen S, Allolio B. Mifepristone (RU 486) in Cushing's syndrome. Eur J Endocrinol. 2007;157:561-569.
    • (2007) Eur J Endocrinol , vol.157 , pp. 561-569
    • Johanssen, S.1    Allolio, B.2
  • 13
    • 0031051692 scopus 로고    scopus 로고
    • RU486 (mifepristone): Mechanisms of action and clinical uses
    • Cadepond F, Ulmann A, Baulieu EE. RU486 (mifepristone): mechanisms of action and clinical uses. Annu Rev Med.1997;48:129-156.
    • (1997) Annu Rev Med , vol.48 , pp. 129-156
    • Cadepond, F.1    Ulmann, A.2    Baulieu, E.E.3
  • 15
    • 0036282611 scopus 로고    scopus 로고
    • Somatostatin receptor subtypes 2 and 5 inhibit corticotropin-releasing hormone-stimulated adrenocorticotropin secretion from AtT-20 cells
    • Strowski MZ, Dashkevicz MP, Parmar RM, et al. Somatostatin receptor subtypes 2 and 5 inhibit corticotropin-releasing hormone-stimulated adrenocorticotropin secretion from AtT-20 cells. Neuroendocrinology. 2002;75:339-346.
    • (2002) Neuroendocrinology , vol.75 , pp. 339-346
    • Strowski, M.Z.1    Dashkevicz, M.P.2    Parmar, R.M.3
  • 16
    • 68449089018 scopus 로고    scopus 로고
    • Differential expression of somatostatin and dopamine receptor subtype genes in adrenocorticotropin (ACTH)-secreting pituitary tumors and silent corticotroph adenomas
    • Tateno T, Kato M, Tani Y, Oyama K, Yamada S, Hirata Y. Differential expression of somatostatin and dopamine receptor subtype genes in adrenocorticotropin (ACTH)-secreting pituitary tumors and silent corticotroph adenomas. Endocr J. 2009;56:579-584.
    • (2009) Endocr J , vol.56 , pp. 579-584
    • Tateno, T.1    Kato, M.2    Tani, Y.3    Oyama, K.4    Yamada, S.5    Hirata, Y.6
  • 17
    • 65249166135 scopus 로고    scopus 로고
    • Coexpression of dopamine and somatostatin receptor subtypes in corticotroph adenomas
    • de Bruin C, Pereira AM, Feelders RA, et al. Coexpression of dopamine and somatostatin receptor subtypes in corticotroph adenomas. J Clin Endocrinol Metab. 2009;94: 1118-1124.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1118-1124
    • De Bruin, C.1    Pereira, A.M.2    Feelders, R.A.3
  • 18
    • 43549106356 scopus 로고    scopus 로고
    • Somatostatin and somatostatin receptors in Cushing's disease
    • Hofland LJ. Somatostatin and somatostatin receptors in Cushing's disease. Mol Cell Endocrinol. 2008;286:199-205.
    • (2008) Mol Cell Endocrinol , vol.286 , pp. 199-205
    • Hofland, L.J.1
  • 19
    • 0036111856 scopus 로고    scopus 로고
    • SOM230: A novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile
    • Bruns C, Lewis I, Briner U, Meno-Tetang G, Weckbecker G. SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile. Eur J Endocrinol. 2002;146:707-716.
    • (2002) Eur J Endocrinol , vol.146 , pp. 707-716
    • Bruns, C.1    Lewis, I.2    Briner, U.3    Meno-Tetang, G.4    Weckbecker, G.5
  • 20
    • 33744982453 scopus 로고    scopus 로고
    • Short- and long-term effects of octreotide and SOM230 on GH, IGF-I, ACTH, corticosterone and ghrelin in rats
    • Suppl International
    • Schmid HA, Silva AP. Short- and long-term effects of octreotide and SOM230 on GH, IGF-I, ACTH, corticosterone and ghrelin in rats. J Endocrinol Invest. 2005;28(11 Suppl International):28-35.
    • (2005) J Endocrinol Invest , vol.28 , Issue.11 , pp. 28-35
    • Schmid, H.A.1    Silva, A.P.2
  • 21
    • 20244376493 scopus 로고    scopus 로고
    • The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5
    • Hofland LJ, Van Der Hoek J, Feelders R, et al. The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5. Eur J Endocrinol. 2005;152: 645-654.
    • (2005) Eur J Endocrinol , vol.152 , pp. 645-654
    • Hofland, L.J.1    Van Der Hoek, J.2    Feelders, R.3
  • 22
    • 84861967547 scopus 로고    scopus 로고
    • Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome
    • Fleseriu M, Biller BM, Findling JW, et al. Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome. J Clin Endocrinol Metab. 2012;97:2039-2049.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 2039-2049
    • Fleseriu, M.1    Biller, B.M.2    Findling, J.W.3
  • 23
    • 37249013214 scopus 로고    scopus 로고
    • NCT00936741. 2013 Accessed September 5 2013
    • ClinicalTrials.gov. NCT00936741. 2013. Available at: http:// clinicaltrials.gov/show/NCT00936741. Accessed September 5, 2013.
    • ClinicalTrials.gov
  • 24
    • 84857826594 scopus 로고    scopus 로고
    • A 12-month phase 3 study of pasireotide in Cushing's disease
    • Colao A, Petersenn S, Newell-Price J, et al. A 12-month phase 3 study of pasireotide in Cushing's disease. N Engl J Med. 2012;366:914-924.
    • (2012) N Engl J Med , vol.366 , pp. 914-924
    • Colao, A.1    Petersenn, S.2    Newell-Price, J.3
  • 25
    • 0033562492 scopus 로고    scopus 로고
    • Inhibition of human pancreatic islet insulin release by receptor-selective somatostatin analogs directed to somatostatin receptor subtype 5
    • Zambre Y, Ling Z, Chen MC, et al. Inhibition of human pancreatic islet insulin release by receptor-selective somatostatin analogs directed to somatostatin receptor subtype 5. Biochem Pharmacol. 1999;57:1159-1164.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1159-1164
    • Zambre, Y.1    Ling, Z.2    Chen, M.C.3
  • 26
    • 33846943674 scopus 로고    scopus 로고
    • Characterization of somatostatin receptor subtype-specific regulation of insulin and glucagon secretion: An in vitro study on isolated human pancreatic islets
    • Singh V, Brendel MD, Zacharias S, et al. Characterization of somatostatin receptor subtype-specific regulation of insulin and glucagon secretion: an in vitro study on isolated human pancreatic islets. J Clin Endocrinol Metab. 2007; 92:673-680.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 673-680
    • Singh, V.1    Brendel, M.D.2    Zacharias, S.3
  • 27
    • 0032780823 scopus 로고    scopus 로고
    • Somatostatin and its receptor family
    • Patel YC. Somatostatin and its receptor family. Front Neuroendocrinol.1999;20:157-198.
    • (1999) Front Neuroendocrinol , vol.20 , pp. 157-198
    • Patel, Y.C.1
  • 29
    • 84874313212 scopus 로고    scopus 로고
    • Management of hyperglycaemia in Cushing's disease: Experts' proposals on the use of pasireotide
    • Reznik Y, Bertherat J, Borson-Chazot F, et al. Management of hyperglycaemia in Cushing's disease: experts' proposals on the use of pasireotide. Diabetes Metab. 2013;39:34-41.
    • (2013) Diabetes Metab , vol.39 , pp. 34-41
    • Reznik, Y.1    Bertherat, J.2    Borson-Chazot, F.3
  • 31
    • 37249013214 scopus 로고    scopus 로고
    • NCT01582061. 2013 Accessed September 5g 2013
    • ClinicalTrials.gov. NCT01582061. 2013. Available at: http:// clinicaltrials.gov/show/NCT01582061. Accessed September 5, 2013.
    • ClinicalTrials.gov
  • 34
    • 77952298716 scopus 로고    scopus 로고
    • Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease
    • Feelders RA, de Bruin C, Pereira AM, et al. Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease. N Engl J Med. 2010;362:1846-1848.
    • (2010) N Engl J Med , vol.362 , pp. 1846-1848
    • Feelders, R.A.1    De Bruin, C.2    Pereira, A.M.3
  • 35
    • 84866646707 scopus 로고    scopus 로고
    • A reappraisal of the medical therapy with steroidgenesis inhibitors in Cushing's syndrome
    • Valassi E, Crespo I, Gich I, Rodríguez J, Webb SM. A reappraisal of the medical therapy with steroidgenesis inhibitors in Cushing's syndrome. Clin Endocrinol (Oxf). 2012;77:735-742.
    • (2012) Clin Endocrinol (Oxf) , vol.77 , pp. 735-742
    • Valassi, E.1    Crespo, I.2    Gich, I.3    Rodríguez, J.4    Webb, S.M.5
  • 36
    • 38949201006 scopus 로고    scopus 로고
    • Ketoconazole revisited: A preoperative or postoperative treatment in Cushing's disease
    • Castinetti F, Morange I, Jaquet P, Conte-Devoix B, Brue T. Ketoconazole revisited: a preoperative or postoperative treatment in Cushing's disease. Eur J Endocrinol 2008;158:91-99.
    • (2008) Eur J Endocrinol , vol.158 , pp. 91-99
    • Castinetti, F.1    Morange, I.2    Jaquet, P.3    Conte-Devoix, B.4    Brue, T.5
  • 37
    • 0028830168 scopus 로고
    • Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production
    • Winquist EL, Laskey J, Crump M, Khamsi F, Shepherd FA. Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production. J Clin Oncol 1995;13:157-164.
    • (1995) J Clin Oncol , vol.13 , pp. 157-164
    • Winquist, E.L.1    Laskey, J.2    Crump, M.3    Khamsi, F.4    Shepherd, F.A.5
  • 39
    • 79952422784 scopus 로고    scopus 로고
    • Efficacy of cabergoline in uncured (persistent or recurrent) Cushing disease after pituitary surgical treatment with or without radiotherapy
    • Lila AR, Gopal RA, Acharya SV, et al. Efficacy of cabergoline in uncured (persistent or recurrent) Cushing disease after pituitary surgical treatment with or without radiotherapy. Endocr Pract. 2010;16:968-976.
    • (2010) Endocr Pract , vol.16 , pp. 968-976
    • Lila, A.R.1    Gopal, R.A.2    Acharya, S.V.3
  • 40
    • 77955904726 scopus 로고    scopus 로고
    • Effectiveness of cabergoline in monotherapy and combined with ketoconazole in the management of Cushing's disease
    • Vilar L, Naves LA, Azevedo MF, et al. Effectiveness of cabergoline in monotherapy and combined with ketoconazole in the management of Cushing's disease. Pituitary. 2010;13:123-129.
    • (2010) Pituitary , vol.13 , pp. 123-129
    • Vilar, L.1    Naves, L.A.2    Azevedo, M.F.3
  • 41
    • 58149389462 scopus 로고    scopus 로고
    • The medical treatment of Cushing's disease: Effectiveness of chronic treatment with the dopamine agonist cabergoline in patients unsuccessfully treated by surgery
    • Pivonello R, De Martino MC, Cappabiana P, et al. The medical treatment of Cushing's disease: effectiveness of chronic treatment with the dopamine agonist cabergoline in patients unsuccessfully treated by surgery. J Clin Endocrinol Metab. 2009;94:223-230.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 223-230
    • Pivonello, R.1    De Martino, M.C.2    Cappabiana, P.3


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