메뉴 건너뛰기




Volumn 55, Issue 1, 2014, Pages 13-19

Normalization of the tumor microenvironment: Evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic

Author keywords

Angiogenesis; Extracellular matrix; Homeostasis; Metalloproteinases; Progression

Indexed keywords

TISSUE INHIBITOR OF METALLOPROTEINASE 2;

EID: 84892694879     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.3109/03008207.2013.867339     Document Type: Article
Times cited : (28)

References (50)
  • 1
    • 79952340427 scopus 로고    scopus 로고
    • Remodeling and homeostasis of the extracellular matrix: Implications for fibrotic diseases and cancer
    • Cox TR, Erler JT. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis Model Mech 2011;4:165-78.
    • (2011) Dis Model Mech , vol.4 , pp. 165-178
    • Cox, T.R.1    Erler, J.T.2
  • 2
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: A dynamic niche in cancer progression
    • Lu P, Weaver VM, Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol 2012;196:395-406.
    • (2012) J Cell Biol , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 3
    • 23744515305 scopus 로고    scopus 로고
    • Modeling dynamic reciprocity: Engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation
    • Nelson CM, Bissell MJ. Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation. Semin Cancer Biol 2005;15:342-52.
    • (2005) Semin Cancer Biol , vol.15 , pp. 342-352
    • Nelson, C.M.1    Bissell, M.J.2
  • 4
    • 70849099495 scopus 로고    scopus 로고
    • The extracellular matrix: Not just pretty fibrils
    • Hynes RO. The extracellular matrix: not just pretty fibrils. Science 2009;326:1216-19.
    • (2009) Science , vol.326 , pp. 1216-1219
    • Hynes, R.O.1
  • 5
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
    • Liotta LA, Steeg PS, Stetler-Stevenson WG. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 1991;64:327-36.
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.A.1    Steeg, P.S.2    Stetler-Stevenson, W.G.3
  • 6
    • 8144228952 scopus 로고    scopus 로고
    • Friends or foes - bipolar effects of the tumour stroma in cancer
    • Mueller MM, Fusenig NE. Friends or foes - bipolar effects of the tumour stroma in cancer. Nat Rev Cancer 2004;4:839-49.
    • (2004) Nat Rev Cancer , vol.4 , pp. 839-849
    • Mueller, M.M.1    Fusenig, N.E.2
  • 7
    • 78449239604 scopus 로고    scopus 로고
    • Metzincin proteases and their inhibitors: Foes or friends in nervous system physiology?
    • Rivera S, Khrestchatisky M, Kaczmarek L, Rosenberg GA, Jaworski DM. Metzincin proteases and their inhibitors: foes or friends in nervous system physiology? J Neurosci 2010;30: 15337-57.
    • (2010) J Neurosci , vol.30 , pp. 15337-15357
    • Rivera, S.1    Khrestchatisky, M.2    Kaczmarek, L.3    Rosenberg, G.A.4    Jaworski, D.M.5
  • 8
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer-trials and tribulations
    • Coussens LM. Matrix metalloproteinase inhibitors and cancer-trials and tribulations. Science 2002;295:2387-92.
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, L.M.1
  • 9
    • 70449732503 scopus 로고    scopus 로고
    • Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer
    • Roy R, Yang J, Moses MA. Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer. J Clin Oncol 2009;27:5287-97.
    • (2009) J Clin Oncol , vol.27 , pp. 5287-5297
    • Roy, R.1    Yang, J.2    Moses, M.A.3
  • 10
    • 84875359149 scopus 로고    scopus 로고
    • The tumor microenvironment: A target for combination therapy of breast cancer
    • Reisfeld RA. The tumor microenvironment: a target for combination therapy of breast cancer. Crit Rev Oncog 2013;18:115-33.
    • (2013) Crit Rev Oncog , vol.18 , pp. 115-133
    • Reisfeld, R.A.1
  • 11
    • 77049113770 scopus 로고    scopus 로고
    • The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity
    • Brew K, Nagase H. The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity. BBA-Mol Cell Res Elsevier BV 2010;1803:55-71.
    • (2010) BBA-Mol Cell Res Elsevier BV , vol.1803 , pp. 55-71
    • Brew, K.1    Nagase, H.2
  • 13
    • 48849107531 scopus 로고    scopus 로고
    • Tissue inhibitors of metalloproteinases in cell signaling: Metalloproteinase-independent biological activities
    • doi: 10.1126/scisignal.127re6
    • Stetler-Stevenson WG. Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities. Sci Signal 2008;1:re6. doi: 10.1126/scisignal.127re6.
    • (2008) Sci Signal , vol.1
    • Stetler-Stevenson, W.G.1
  • 16
    • 33748371637 scopus 로고    scopus 로고
    • Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein
    • Jung K-K, Liu X-W, Chirco R, Fridman R, Kim H-RC. Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein. EMBO J. Nature Publishing Group 2006;25:3934-42.
    • (2006) EMBO J. Nature Publishing Group , vol.25 , pp. 3934-3942
    • Jung, K.-K.1    Liu, X.-W.2    Chirco, R.3    Fridman, R.4    H-Rc, K.5
  • 17
    • 0037393850 scopus 로고    scopus 로고
    • A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): Inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
    • Qi JH, Ebrahem Q, Moore N, Murphy G, Claesson-Welsh L, Bond M, Baker A, Anand-Apte B. A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med 2003;9: 407-15.
    • (2003) Nat Med , vol.9 , pp. 407-415
    • Qi, J.H.1    Ebrahem, Q.2    Moore, N.3    Murphy, G.4    Claesson-Welsh, L.5    Bond, M.6    Baker, A.7    Anand-Apte, B.8
  • 19
    • 19044387522 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an antimitogenic signal
    • Pérez-Mart́nez L, Jaworski DM. Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an antimitogenic signal. J Neurosci 2005;25:4917-29.
    • (2005) J Neurosci , vol.25 , pp. 4917-4929
    • Pérez-Mart́nez, L.1    Jaworski, D.M.2
  • 21
    • 83555168313 scopus 로고    scopus 로고
    • An alternate perspective on the roles of TIMPs and MMPs in pathology
    • Moore CS, Crocker SJ. An alternate perspective on the roles of TIMPs and MMPs in pathology. AJPA Elsevier Inc 2012;180: 12-16.
    • (2012) AJPA Elsevier Inc , vol.180 , pp. 12-16
    • Moore, C.S.1    Crocker, S.J.2
  • 22
    • 14744275382 scopus 로고    scopus 로고
    • Serum tissue inhibitors of metalloproteinase-1 and-2 in patients with non-small cell lung cancer
    • Suemitsu R, Yoshino I, Tomiyasu M, Fukuyama S, Okamoto T, Maehara Y. Serum tissue inhibitors of metalloproteinase-1 and-2 in patients with non-small cell lung cancer. Surg Today 2004;34: 896-901.
    • (2004) Surg Today , vol.34 , pp. 896-901
    • Suemitsu, R.1    Yoshino, I.2    Tomiyasu, M.3    Fukuyama, S.4    Okamoto, T.5    Maehara, Y.6
  • 23
    • 0034859529 scopus 로고    scopus 로고
    • Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma
    • Nakada M, Kita D, Futami K, Yamashita J, Fujimoto N, Sato H, Okada Y. Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma. J Neurosurg 2001;94:464-73.
    • (2001) J Neurosurg , vol.94 , pp. 464-473
    • Nakada, M.1    Kita, D.2    Futami, K.3    Yamashita, J.4    Fujimoto, N.5    Sato, H.6    Okada, Y.7
  • 25
    • 84873135108 scopus 로고    scopus 로고
    • The expression and clinical significance of matrix metalloproteinase 7 and tissue inhibitor of matrix metalloproteinases 2 in clear cell renal cell carcinoma
    • Lu H. The expression and clinical significance of matrix metalloproteinase 7 and tissue inhibitor of matrix metalloproteinases 2 in clear cell renal cell carcinoma. Exp Ther Med 2013;5:890-6.
    • (2013) Exp Ther Med , vol.5 , pp. 890-896
    • Lu, H.1
  • 28
    • 84863106677 scopus 로고    scopus 로고
    • Analysis of the MMPdependent and independent functions of tissue inhibitor of metalloproteinase-2 on the invasiveness of breast cancer cells
    • Walsh LA, Cepeda MA, Damjanovski S. Analysis of the MMPdependent and independent functions of tissue inhibitor of metalloproteinase-2 on the invasiveness of breast cancer cells. J Cell Commun Signal 2012;6:87-95.
    • (2012) J Cell Commun Signal , vol.6 , pp. 87-95
    • Walsh, L.A.1    Cepeda, M.A.2    Damjanovski, S.3
  • 31
    • 0028198497 scopus 로고
    • Characterization of the promoter of the gene encoding human tissue inhibitor of metalloproteinases-2 (TIMP-2)
    • De Clerck YA, Darville MI, Eeckhout Y, Rousseau GG. Characterization of the promoter of the gene encoding human tissue inhibitor of metalloproteinases-2 (TIMP-2). Gene 1994;139: 185-91.
    • (1994) Gene , vol.139 , pp. 185-191
    • De Clerck, Y.A.1    Darville, M.I.2    Eeckhout, Y.3    Rousseau, G.G.4
  • 32
    • 43449106192 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-2 G-418 C polymorphism is associated with an increased risk of gastric cancer in a Chinese population
    • Yang L, Gu H-J, Zhu H-J, Sun Q-M, Cong R-H, Zhou B, Tang N-P, Wang B. Tissue inhibitor of metalloproteinase-2 G-418 C polymorphism is associated with an increased risk of gastric cancer in a Chinese population. Eur J Surg Oncol 2008;34:636-41.
    • (2008) Eur J Surg Oncol , vol.34 , pp. 636-641
    • Yang, L.1    Gu, H.-J.2    Zhu, H.-J.3    Sun, Q.-M.4    Cong, R.-H.5    Zhou, B.6    Tang, N.-P.7    Wang, B.8
  • 33
    • 84860606639 scopus 로고    scopus 로고
    • Association of promoter polymorphisms in MMP2 and TIMP2 with prostate cancer susceptibility in North India
    • Srivastava P, Lone TA, Kapoor R, Mittal RD. Association of promoter polymorphisms in MMP2 and TIMP2 with prostate cancer susceptibility in North India. Arch Med Res 2012;43: 117-24.
    • (2012) Arch Med Res , vol.43 , pp. 117-124
    • Srivastava, P.1    Lone, T.A.2    Kapoor, R.3    Mittal, R.D.4
  • 34
    • 78851470329 scopus 로고    scopus 로고
    • Clinical characteristics of TIMP2, MMP2, and MMP9 gene polymorphisms in colorectal cancer
    • Park KS, Kim SJ, Kim KH, Kim JC. Clinical characteristics of TIMP2, MMP2, and MMP9 gene polymorphisms in colorectal cancer. J Gastroenterol Hepatol 2011;26:391-7.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 391-397
    • Park, K.S.1    Kim, S.J.2    Kim, K.H.3    Kim, J.C.4
  • 36
    • 33745103349 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms of tissue inhibitor of metalloproteinase genes in familial moyamoya disease
    • discussion 1074-80
    • Kang H-S, Kim S-K, Cho B-K, Kim Y-Y, Hwang Y-S, Wang K-C. Single nucleotide polymorphisms of tissue inhibitor of metalloproteinase genes in familial moyamoya disease. Neurosurgery 2006;58: 1074-80. discussion 1074-80.
    • (2006) Neurosurgery , vol.58 , pp. 1074-1080
    • Kang, H.-S.1    Kim, S.-K.2    Cho, B.-K.3    Kim, Y.-Y.4    Hwang, Y.-S.5    Wang, K.-C.6
  • 38
    • 0035793638 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition
    • Hoegy SE, Oh HR, Corcoran ML, Stetler-Stevenson WG. Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition. J Biol Chem 2001;276:3203-14.
    • (2001) J Biol Chem , vol.276 , pp. 3203-3214
    • Hoegy, S.E.1    Oh, H.R.2    Corcoran, M.L.3    Stetler-Stevenson, W.G.4
  • 39
    • 33645646321 scopus 로고    scopus 로고
    • Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells
    • Seo D-W, Li H, Qu C-K, Oh J, Kim Y-S, Diaz T, Wei B, Han J-W, Stetler-Stevenson WG. Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells. J Biol Chem 2006;281:3711-21.
    • (2006) J Biol Chem , vol.281 , pp. 3711-3721
    • Seo, D.-W.1    Li, H.2    Qu, C.-K.3    Oh, J.4    Kim, Y.-S.5    Diaz, T.6    Wei, B.7    Han, J.-W.8    Stetler-Stevenson, W.G.9
  • 41
    • 77649143135 scopus 로고    scopus 로고
    • TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells
    • Lee S-J, Tsang PS, Diaz TM, Wei B-Y, Stetler-Stevenson WG. TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells. Lab Investig 2010; 90:374-82.
    • (2010) Lab Investig , vol.90 , pp. 374-382
    • Lee, S.-J.1    Tsang, P.S.2    Diaz, T.M.3    Wei, B.-Y.4    Stetler-Stevenson, W.G.5
  • 43
    • 84893378509 scopus 로고    scopus 로고
    • TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells
    • Bourboulia D, Han H, Jensen-Taubman S, Gavil N, Isaac B, Wei B, Neckers L, Stetler-Stevenson WG. TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells. Oncotarget 2013;4: 163-73.
    • (2013) Oncotarget , vol.4 , pp. 163-173
    • Bourboulia, D.1    Han, H.2    Jensen-Taubman, S.3    Gavil, N.4    Isaac, B.5    Wei, B.6    Neckers, L.7    Stetler-Stevenson, W.G.8
  • 44
    • 84896697400 scopus 로고    scopus 로고
    • An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells
    • [Epub ahead of print]. doi:10. 1038/onc.2013.61
    • Han H, Bourboulia D, Jensen-Taubman S, Isaac B, Wei B, Stetler-Stevenson WG. An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells. Oncogene 2013. [Epub ahead of print]. doi:10. 1038/onc.2013.61
    • (2013) Oncogene
    • Han, H.1    Bourboulia, D.2    Jensen-Taubman, S.3    Isaac, B.4    Wei, B.5    Stetler-Stevenson, W.G.6
  • 45
    • 0030012534 scopus 로고    scopus 로고
    • Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion
    • Imren S, Kohn DB, Shimada H, Blavier L, DeClerck YA. Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion. Cancer Res 1996;56:2891-5.
    • (1996) Cancer Res , vol.56 , pp. 2891-2895
    • Imren, S.1    Kohn, D.B.2    Shimada, H.3    Blavier, L.4    Declerck, Y.A.5
  • 49
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
    • Jain RK. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat Med Nature Publishing Group 2001;7:987-9.
    • (2001) Nat Med Nature Publishing Group , vol.7 , pp. 987-989
    • Jain, R.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.