Sexual Desire in Trans Persons: Associations with Sex Reassignment Treatment

Journal of Sexual Medicine

Volumn 11, Issue 1, 2014, Pages 107-118

  Wierckx, Katrien ^a   Elaut, Els ^a   Van Hoorde, Birgit ^a   Heylens, Gunter ^a   De Cuypere, Griet ^a   Monstrey, Stan ^a   Weyers, Steven ^a   Hoebeke, Piet ^a   T'Sjoen, Guy ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Cross Sex Hormone Therapy; Gender Identity Disorder; Sexual Desire; Sexual Functioning; Transsexual

Indexed keywords

ADULT; ARTICLE; FEMALE; GENDER DYSPHORIA; HORMONAL THERAPY; HUMAN; HYPOACTIVE SEXUAL DESIRE DISORDER; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MIDDLE AGED; PATIENT SATISFACTION; PREVALENCE; PRIORITY JOURNAL; QUESTIONNAIRE; SEX REASSIGNMENT; SEXUAL BEHAVIOR; SEXUALITY; TRANSSEXUALITY; VAGINA RECONSTRUCTION;

CROSS-SEX HORMONE THERAPY; GENDER IDENTITY DISORDER; SEXUAL DESIRE; SEXUAL FUNCTIONING; TRANSSEXUAL;

ADULT; CROSS-SECTIONAL STUDIES; FEMALE; GONADAL STEROID HORMONES; HUMANS; LIBIDO; MALE; MIDDLE AGED; PERSONAL SATISFACTION; PREVALENCE; QUESTIONNAIRES; SEX REASSIGNMENT PROCEDURES; SEXUAL BEHAVIOR; SEXUAL DYSFUNCTIONS, PSYCHOLOGICAL; TRANSGENDERED PERSONS; VAGINA;

EID: 84892677659     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/jsm.12365     Document Type: Article

References (57)

1. Wierckx K, Mueller S, Weyers S, Van Caenegem E, Roef G, Heylens G, T'Sjoen G. A long-term evaluation of cross-sex hormone treatment in trans persons. J Sex Med 2012;9:2641-2651.
2. Hembree WC, Cohen-Kettenis P, Delemarre-van de Waal HA, de Waal HA, Gooren LJ, Meyer WJ 3rd, Spack NP, Tangpricha V, Montori VM. Endocrine treatment of trans persons: An Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2009;94:3132-3154.
3. Bancroft J. The endocrinology of sexual arousal. J Endocrinol 2005;186:411-427.
4. Yassin AA, Saad F. Improvement of sexual function in men with late-onset hypogonadism treated with testosterone only. J Sex Med 2007;4:497-501.
5. Wang C, Cunningham G, Dobs A, Iranmanesh A, Matsumoto AM, Snyder PJ, Weber T, Berman N, Hull L, Swerdloff RS. Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men. J Clin Endocrinol Metab 2004;89:2085-2098.
6. Carani C, Zini D, Baldini A, Della CL, Ghizzani A, Marrama P. Effects of androgen treatment in impotent men with normal and low levels of free testosterone. Arch Sex Behav 1990;19:223-234.
7. Buena F, Swerdloff RS, Steiner BS, Lutchmansingh P, Peterson MA, Pandian MR, Galmarini M, Bhasin S. Sexual function does not change when serum testosterone levels are pharmacologically varied within the normal male range. Fertil Steril 1993;59:1118-1123.
8. Hajjar RR, Kaiser FE, Morley JE. Outcomes of long-term testosterone replacement in older hypogonadal males: A retrospective analysis. J Clin Endocrinol Metab 1997;82:3793-3796.
9. Yates WR, Perry PJ, MacIndoe J, Holman T, Ellingrod V. Psychosexual effects of three doses of testosterone cycling in normal men. Biol Psychiatry 1999;45:254-260.
10. Riley A, Riley E. Controlled studies on women presenting with sexual disorders: I. Endocrine status. J Sex Marital Ther 2000;26:269-283.
11. Turna B, Apaydin E, Semerci B, Altay B, Cikili N, Nazli O. Women with low libido: Correlation of decreased androgen levels with female sexual function index. Int J Impot Res 2005;17:148-153.
12. Santoro N, Torrens J, Crawford S, Allsworth JE, Finkelstein JS, Gold EB, Korenman S, Lasley WL, Luborsky JL, McConnell D, Sowers MF, Weiss G. Correlates of circulating androgens in mid-life women: The study of women's health across the nation. J Clin Endocrinol Metab 2005;90:4836-4845.
13. Davis SR, Davison SL, Donath S, Bell RJ. Circulating androgen levels in self-reported sexual function in women. JAMA 2005;294:91-96.
14. Bancroft J, Sherwin B, Alexander GM, Davidson DW, Walker A. Contraceptives, androgens, and the sexuality of young women. 2. The role of androgens. Arch Sex Behav 1991;20:121-135.
15. Burrows LJ, Basha M, Goldstein A. The effects of hormonal contraception on female sexuality: A review. J Sex Med 2012;9:2213-2223.
16. Davis SR, van der Mooren MJ, van Lunsen RH, Lopes P, Ribot C, Rees M, Moufarege A, Rodenberg C, Buch A, Purdie DW. Efficacy and safety of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: A randomized, placebo-controlled trial. Menopause 2006;13:387-396.
17. Davis SR, Moreau M, Kroll R, Bouchard C, Panay N, Gass M, Braunstein GD, Hirschberg AL, Rodenberg C, Pack S, Koch H, Moufarege A, Studd J. Testosterone for low libido in postmenopausal women not taking estrogen. N Engl J Med 2008;359:2005-2017.
18. Shifren JL, Braunstein GD, Simon JA, Casson PR, Buster JE, Redmond GP, Burki RE, Ginsburg ES, Rosen RC, Leiblum SR, Caramelli KE, Mazer NA. Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. N Engl J Med 2000;343:682-688.
19. Grades NM, Jacobson DJ, McGree ME, St Sauver JL, Lieber MM, Nehra A, Girman CJ, Klee GG, Jacobson SJ. The associations between serum sex steroids, erectile function and sex drive: The Olmsted County Study of urinary symptoms and heath status among men. J Sex Med 2008;5:2209-2220.
20. Basar MM, Aydin G, Mert HC, Keles I, Caglayan O, Orkun S, Batislam E. Relationship between serum sex steroids and aging male symptoms score and International Index of Erectile Function. Urology 2005;66:597-601.
21. Avis NE, Stellato R, Crawford S, Johannes C, Longcope C. Menopause 2000;7:297-309.
22. Cawood EH, Bancroft J. Steroid hormones, the menopause, sexuality and well-being of women. Psychol Med 1996;26:925-936.
23. Dennerstein L, Burrows G, Wood C, Hyman G. Hormones and sexuality: The effects of estrogen and progestogen. Obstet Gynecol 1980;56:316-322.
24. Dow M, Hart D, Forrest C. Hormonal treatments of unresponsiveness in post-menopausal women: A comparative study. Br J Obstet Gynaecol 1983;90:361-366.
25. Redmond G. Hormones and sexual function. Int J Fertil 1999;44:193-197.
26. Graham C, Ramos R, Bancroft J, Maglaya C, Farley T. The effects of steroidal contraceptives on the well-being and sexuality of women: A double-blind, placebo-controlled, two-centre study of combined and progestogen-only methods. Contraception 1995;52:363-369.
27. Cohen-Kettenis PT, Van Goozen SHM. Sex reassignment of adolescent transsexuals: A follow-up study. J Am Acad Child Adolesc Psychiatry 1997;36:263-271.
28. Schroder M, Carroll RA. New women: Sexological outcomes of male-to-female gender reassignment surgery. J Sex Educ Ther 1999;24:137-146.
29. Mate-Kole C, Freschi M, Robin A. A controlled study of psychological and social change after surgical gender reassignment in selected male transsexuals. Br J Psychiatry 1990;157:261-264.
30. Sørensen T. A follow-up study of operated transsexual males. Acta Psychiatr Scand 1981;63:486-503.
31. Wierckx K, Van Caenegem E, Elaut E, Vandepeer F, Dedecker D, Toye K, Weyers S, Hoebeke P, Monstrey S, De Cuypere G, T'Sjoen G. Quality of life and sexual health after sex reassignment surgery in trans men. J Sex Med 2011;8:3379-3388.
32. Klein C, Gorzalska BB. Sexual functioning in transsexuals following hormone therapy and genital surgery: A review. J Sex Med 2009;6:2922-2939.
33. Monstrey S, Hoebeke P, Selvaggi G, Ceulemans P, Van Landuyt K, Blondeel P, Hamdi M, Roche N, Weyers S, De Cuypere G. Penile reconstruction: Is the radial forearm flap really the standard technique? Plast Reconstr Surg 2009;124:510-518.
34. De Cuypere G, T'Sjoen G, Beerten R, Selvaggi G, De Sutter P, Hoebeke P, Monstrey S, Vansteenwegen A, Rubens R. Sexual and physical health after sex reassignment surgery. Arch Sex Behav 2005;34:679-690.
35. Rehman J, Lazer S, Benet AE, Schaefer LC, Melman A. The reported sex and surgery satisfactions of 28 postoperative male-to-female transsexual patients. Arch Sex Behav 1999;28:71-89.
36. Smith YLS, Van Goozen SHM, Cohen-Kettenis PT. Adolescents with gender identity disorder who were accepted or rejected for sex reassignment surgery: A prospective follow-up study. J Am Acad Child Adolesc Psychiatry 2001;40:472-481.
37. Lief HI, Hubschman L. Orgasm in the postoperative transsexual. Arch Sex Behav 1993;22:145-155.
38. Lobato M, Koff WJ, Manenti C, Seger DF, Salvador J, Fortes MGB, Petry AR, Silveira E, Henriques AA. Follow-up of sex reassignment surgery in transsexuals: A Brazilian cohort. Arch Sex Behav 2006;35:711-715.
39. Wierckx K, Elaut E, Van Caenegem E, Van de peer F, Dedecker D, Vanhoudenhove E, T'Sjoen G. Sexual desire in female-to-male trans persons: An exploration of the role of testosterone replacement. Eur J Endocrinol 2011;165:331-337.
40. Wierckx K, Elaut E, Motmans J, Heylens G, De Cuypere G, Anseeuw E, Geerts L, T'Sjoen G. Quality of life in trans persons: A case control study. manuscript submitted to Arch Sex Behav. Submitted.
41. Wierckx K, Elaut E, Declercq E, De Cuypere G, Taes Y, Kaufman JM, T'Sjoen G. Prevalence of cardiovascular disease and cancer during cross-sex hormone therapy in a large cohort of trans persons: A case control study. Eur J Endocrinol 2013;169:471-478.
42. Weyers S, Elaut E, De Sutter P, Gerris J, T'Sjoen G, Heylens G, De Cuypere G, Verstraelen H. Long-term assessment of the Physical, Mental, and Sexual Health among transsexual woman. J Sex Med 2009;6:752-760.
43. Elaut E, De Cuypere G, De Sutter P, Gijs L, Van Trotsenburg M, Heylens G, Kaufman JM, Rubens R, T'Sjoen G. Hypoactive sexual desire in trans women: Prevalence and association with testosterone levels. Eur J Endocrinol 2008;158:393-399.
44. Basson R, Berman J, Burnett A, Derogatis L, Ferguson D, Fourcroy J, Goldstein I, Graziottin A, Heiman J, Laan E, Leiblum S, Padma-Nathan H, Rosen R, Segraves K, Segraves RT, Shabsigh R, Sipski M, Wagner G, Whipple B. Report of the international consensus development conference on female sexual dysfunction: Definitions and classifications. J Urol 2000;163:888-893.
45. Ware JE. SF-12 Health Survey. Washington D.C (1994, 2002), WA: Medical Outcomes. Trustand QualityMetric Inc.
46. Rosen RC, Shifren JL, Monz BU, Odom DM, Russo PA, Johannes CB. Correlates of sexually related personal distress in women with low sexual desire. J Sex Med 2009;6:1549-1560.
47. Leiblum SR, Koochaki PE, Rodenberg CA, Barton IP, Rosen RC. Hypoactive sexual desire disorder in postmenopausal women: U.S. results from the Women's International Study of Health and Sexuality (WISHeS). Menopause 2006;13:46-56.
48. Kedde H. Seksuele disfuncties in Nederland: Prevalentie en samenhangende factoren. Tijdschrift voor Seksuologie 2012;36:98-108.
49. Christensen BS, Grønbæk M, Osler M, Pedersen BV, Graugaard C, Frisch M. Sexual dysfunctions and difficulties in Denmark: Prevalence and associated sociodemographic factors. Arch Sex Behav 2011;40:121-132.
50. Fugl-Meyer AR, Fulg-Meyer K. Sexual disabilities, problems and satisfaction in 18-74 year old Swedes. Scand J Sexol 1999;2:79-105.
51. Shifren JL, Monz BU, Russo PA, Segreti A, Johannes CB. Sexual problems and distress in United States women: Prevalence and correlates. Obstet Gynecol 2008;112:970-978.
52. Buysse A, Caen M, Dewaele A, Enzlin P, Lievens J, T'Sjoen G, Van Houtte M, Vermeersch H. Seksuele disfuncties. In: Buysse A, Caen M, Dewaele A, Enzlin P, Lievens J, T'Sjoen G, Van Houtte M, Vermeersch H, eds. Seksuele gezondheid in Vlaanderen [Sexual health in Flanders]. Gent: Academia Press; 2013:193-214.
53. Hayes RD, Dennerstein L, Bennett CM, Sidat M, Gurrin LC, Fairley CK. Risk factors for female sexual dysfunction in the general population: Exploring factors associated with low sexual function and sexual distress. J Sex Med 2008;5:1681-1693.
54. Applebaum GT. Lesbian sexual function and dysfunction. Doctoral Dissertation, California School of Professional Psychology. Los Angeles, 1983.
55. Basson R. The female sexual response: A different model. J Sex Marital Ther 2000;26:51-65.
56. Brotto LA. The DSM diagnostic criteria for hypoactive sexual desire disorder in men. J Sex Med 2010;7:2015-2030.
57. Brotto LA. The DSM diagnostic criteria for hypoactive sexual desire disorder in women. Arch Sex Behav 2010;39:221-239.