Structural and mutational analyses of Aes, an inhibitor of MalT in Escherichia coli

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 2, 2014, Pages 268-277

  Schiefner, André ^a   Gerber, Kinga ^b   Brosig, Alexander ^b   Boos, Winfried ^b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

Acyl esterase; Aes; Inhibition of MalT; MalT dependent regulation; Site directed mutagenesis; X ray crystallography

Indexed keywords

ACYL ESTERASE; ALPHA HYDROLASE; ASPARTIC ACID; BACTERIAL PROTEIN; BETA HYDROLASE; DIMER; ESTERASE; HISTIDINE; HOMODIMER; MALTODEXTRIN; MALTOSE; PROTEIN MALT; SERINE; SULFONE DERIVATIVE; UNCLASSIFIED DRUG;

ALANINE SCANNING MUTAGENESIS; ARTICLE; BACTERIAL GENE; COVALENT BOND; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; GEL PERMEATION CHROMATOGRAPHY; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; SURFACE PROPERTY; WILD TYPE; X RAY DIFFRACTION;

ESCHERICHIA COLI;

ACYL ESTERASE; AES; INHIBITION OF MALT; MALT-DEPENDENT REGULATION; SITE-DIRECTED MUTAGENESIS; X-RAY CRYSTALLOGRAPHY;

ACETYLESTERASE; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHENYLMETHYLSULFONYL FLUORIDE; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; TRANSCRIPTION FACTORS;

EID: 84892672372     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24383     Document Type: Article

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