Design, evaluation, and screening methods for efficient targeted mutagenesis with transcription activator-like effector nucleases in medaka

Development Growth and Differentiation

Volumn 56, Issue 1, 2014, Pages 98-107

  Ansai, Satoshi ^a   Inohaya, Keiji ^b   Yoshiura, Yasutoshi ^c   Schartl, Manfred ^d,e   Uemura, Norihito ^a   Takahashi, Ryosuke ^a   Kinoshita, Masato ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c FISHERIES RESEARCH AGENCY   (Japan)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

Heteroduplex mobility assay; Medaka; Microhomology; Targeted mutagenesis; Transcription activator like effector nuclease

Indexed keywords

GENOMIC DNA; NUCLEASE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; EMBRYO; ENZYME ACTIVITY; GENE LOCUS; GENETIC SCREENING; GENOME; GENOTYPE; HETERODUPLEX MOBILITY ASSAY; IN VIVO STUDY; INDUCED MUTATION; MICROCHIP ELECTROPHORESIS; MUTAGENESIS; NONHUMAN; NUCLEIC ACID ANALYSIS; ORYZIAS LATIPES; PRACTICE GUIDELINE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; ANIMAL; GENE TARGETING; GENETICS; HETERODUPLEX ANALYSIS; METABOLISM; ORYZIAS; PROCEDURES; SITE DIRECTED MUTAGENESIS;

ORYZIAS LATIPES; ORYZIINAE;

ANIMALS; ENDODEOXYRIBONUCLEASES; GENE TARGETING; HETERODUPLEX ANALYSIS; MUTAGENESIS, SITE-DIRECTED; ORYZIAS;

EID: 84892670385     PISSN: 00121592     EISSN: 1440169X     Source Type: Journal    
DOI: 10.1111/dgd.12104     Document Type: Article

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