Designer nodal/BMP2 chimeras mimic nodal signaling, promote chondrogenesis, and reveal a BMP2-like structure

Journal of Biological Chemistry

Volumn 289, Issue 3, 2014, Pages 1788-1797

  Esquivies, Luis ^a   Blackler, Alissa ^b   Peran, Macarena ^a,c   Rodriguez Esteban, Concepcion ^a   Izpisua Belmonte, Juan Carlos ^a   Booker, Evan ^b   Gray, Peter C ^b   Ahn, Chihoon ^d,e   Kwiatkowski, Witek ^a   Choe, Senyon ^a,e  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c UNIVERSITY OF JAÉN   (Spain)

^d University of Science and Technology (UST)   (South Korea)

^e Gachon University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE DERIVED STEM CELLS; BIOCHEMICAL STUDIES; CHONDROGENESIS; CHONDROGENIC DIFFERENTIATION; LEFT-RIGHT ASYMMETRY; SIGNALING PATHWAYS;

CARTILAGE; STEM CELLS;

LIGANDS;

BONE MORPHOGENETIC PROTEIN 2; CO RECEPTOR CRIPTO; PROTEIN NB250; PROTEIN NB260; PROTEIN NB264; PROTEIN NODAL; RECEPTOR; SCAFFOLD PROTEIN; SMAD2 PROTEIN; UNCLASSIFIED DRUG; BMP2 PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HYBRID PROTEIN; NODAL PROTEIN, HUMAN; SIGNAL PEPTIDE; TDGF1 PROTEIN, HUMAN; TUMOR PROTEIN;

ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CHICK EMBRYO; CHIMERA; CHONDROGENESIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; EMBRYO; HUMAN; IN VITRO STUDY; NONHUMAN; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN REFOLDING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; ADIPOSE TISSUE; ADULT; CARTILAGE; CELL LINE; CHEMISTRY; DRUG EFFECTS; FEMALE; GENETICS; METABOLISM; PATHOLOGY; STEM CELL;

ADIPOSE TISSUE; ADULT; BONE MORPHOGENETIC PROTEIN 2; CARTILAGE; CELL LINE; CHONDROGENESIS; FEMALE; GPI-LINKED PROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NEOPLASM PROTEINS; NODAL PROTEIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; STEM CELLS;

EID: 84892664182     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.529180     Document Type: Article

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