Combination of hybrid peptide with biodegradable gelatin hydrogel for controlled release and enhancement of anti-tumor activity in vivo

Journal of Controlled Release

Volumn 176, Issue 1, 2014, Pages 1-7

  Gaowa, Arong ^a   Horibe, Tomohisa ^a   Kohno, Masayuki ^a   Sato, Keisuke ^b   Harada, Hiroshi ^a   Hiraoka, Masahiro ^a   Tabata, Yasuhiko ^b   Kawakami, Koji ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Anti tumor activity; Controlled release; DDS; Gelatin hydrogel; Hybrid peptide; Pharmacokinetics

Indexed keywords

ANTI-TUMOR ACTIVITIES; CONTROLLED RELEASE; DDS; GELATIN HYDROGELS; HYBRID PEPTIDES;

CYTOTOXICITY; HYDROGELS; MAMMALS; PHARMACOKINETICS;

PEPTIDES;

GELATIN; HYBRID PROTEIN; NANOPARTICLE; PHOSPHATE BUFFERED SALINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CIRCULATION TIME; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; HUMAN; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANTI-TUMOR ACTIVITY; CONTROLLED RELEASE; DDS; GELATIN HYDROGEL; HYBRID PEPTIDE; PHARMACOKINETICS;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; FEMALE; GELATIN; HEK293 CELLS; HUMANS; HYDROGELS; MICE; MICE, INBRED BALB C; NEOPLASMS; RECOMBINANT FUSION PROTEINS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84892654869     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.12.021     Document Type: Article

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