Albendazole-induced associated acute hepatitis and bicytopenia

Scandinavian Journal of Infectious Diseases

Volumn 46, Issue 2, 2014, Pages 149-151

  Ben Fredj, Nadia ^a   Chaabane, Amel ^a   Chadly, Zohra ^a   Ben Fadhel, Najeh ^a   Boughattas, Naceur A ^a   Aouam, Karim ^a  

^a Laboratoire de Biochimie   (Tunisia)

Author keywords

Albendazole; Hepatitis; ThrombocytopeniaAnemia

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBENDAZOLE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN;

ACUTE HEPATITIS; ADULT; ARTICLE; BICYTOPENIA; CASE REPORT; CYTOPENIA; DRUG WITHDRAWAL; HUMAN; HYDATIDIFORM MOLE; MALE; POSTOPERATIVE CARE;

ADULT; ALBENDAZOLE; ANEMIA; ANTHELMINTICS; DRUG-INDUCED LIVER INJURY; HUMANS; MALE; THROMBOCYTOPENIA;

EID: 84892634510     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2013.835068     Document Type: Article

References (16)

1. Aggarwal P, Wali JP. Albendazole in the treatment of pulmonary echinococcosis. Thorax 1991; 46: 599-600.
2. Smego RA Jr, Bhatti S, Khaliq AA, Beg MA. Percutaneous aspiration-injection-reaspiration drainage plus albendazole or mebendazole for hepatic cystic echinococcosis: a metaanalysis. Clin Infect Dis 2003; 37: 1073-83.
3. Teggi A, Lastilla GM, De Rosa F. Therapy of human hydatid disease with mebendazole and albendazole. Antimicrob Agents Chemother 1993; 37: 1679-84.
4. Polat C, Dervisoglu A, Hokelek M, Yetim I, Buyukkarabacak Y, Ozkutuk Y, et al. Dual treatment of albendazole in hepatic hydatidosis: new therapeutic modality in 52 cases. J Gastroenterol Hepatol 2005; 20: 421-5.
5. Choi GY, Yang HW, Cho SH, Kang DW, Go H, Lee WC, et al. Acute drug-induced hepatitis caused by albendazole. J Korean Med Sci 2008; 23: 903-5.
6. Amoruso C, Fuoti M, Miceli V, Zito E, Celano MR, De Giorgi A, et al. Acute hepatitis as a side effect of albendazole: a pediatric case. Pediatr Med Chir 2009; 31: 262-4.
7. Yildiz BO, Haznedarog ? lu IC, Cö p l ü L. Albendazoleinduced amegakaryocytic thrombocytopenic purpura. Ann Pharmacother 1998; 32: 842.
8. Horton J. Albendazole: a review of anthelmintic efficacy and safety in humans. Parasitology 2000; 121: 113-32.
9. García-Corté SM, Lucena MI, Pachkoria K, Borraz Y, Hidalgo R, Andrade RJ; Spanish Group for the Study of Drug-induced Liver Disease. Evaluation of Naranjo adverse drug reactions probability scale in causality assessment of drug-induced liver injury. Aliment Pharmacol Ther 2008; 27: 780-9.
10. Khuroo MS, Dar MY, Yattoo GN, Zargar SA, Javaid G, Khan BA, et al. Percutaneous drainage versus albendazole therapy in hepatic hydatidosis: a prospective, randomized study. Gastroenterology 1993; 104: 1452-9.
11. Sekhon SS, Roy V. Thrombocytopenia in adults: a practical approach to evaluation and management. South Med J 2006; 99: 491-8.
12. World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System. Geneva: WHO; 2011. Available at: http://www.who.int/vmnis/indicators/ haemoglobin.pdf (accessed 12 august 2013).
13. Opatrny L, Prichard R, Snell L, Maclean JD. Death related to albendazole-induced pancytopenia: case report and review. Am J Trop Med Hyg 2005; 72: 291-4.
14. Akbal E, Akyürek O, Sarbacak C E, Günefl F, Altnbafl M. Albendazole-induced bicytopenia: case report. Turk J Hematol 2008; 25: 45-7.
15. Morris DL, Dykes PW, Marriner S, Bogan J, Burrows F, Skeene-Smith H, et al. Albendazole: objective evidence of response in human hydatid disease. JAMA 1985; 253: 2053-7.
16. Morris DL, Smith PG. Albendazole in hydatid disease-hepatocellular toxicity. Trans R Soc Trop Med Hyg 1987; 81: 343-4.