-
1
-
-
77951999444
-
-
American Cancer Society (ACS)
-
American Cancer Society (ACS), Breast Cancer Statistics, 2013. Available at: http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/breast-cancer-key- statistics, 2013.
-
(2013)
Breast Cancer Statistics, 2013
-
-
-
2
-
-
84862819412
-
Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
-
et al.
-
Guo S, Liu M, Wang G, et al. Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells. Biochim Biophys Acta 2012; 1825: 207-22.
-
(2012)
Biochim Biophys Acta
, vol.1825
, pp. 207-222
-
-
Guo, S.1
Liu, M.2
Wang, G.3
-
5
-
-
0036682013
-
Nutrition and survival after the diagnosis of breast cancer: A review of the evidence
-
Rock CL, Demark-Wahnefried W,. Nutrition and survival after the diagnosis of breast cancer: a review of the evidence. J Clin Oncol 2002 20: 3302-16.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3302-3316
-
-
Rock, C.L.1
Demark-Wahnefried, W.2
-
6
-
-
79955604487
-
Role of obesity-associated dysfunctional adipose tissue in cancer: A molecular nutrition approach
-
et al.
-
Prieto-Hontoria PL, Perez-Matute P, Fernandez-Galilea M, et al. Role of obesity-associated dysfunctional adipose tissue in cancer: a molecular nutrition approach. Biochim Biophys Acta 2011; 1807: 664-78.
-
(2011)
Biochim Biophys Acta
, vol.1807
, pp. 664-678
-
-
Prieto-Hontoria, P.L.1
Perez-Matute, P.2
Fernandez-Galilea, M.3
-
7
-
-
66549110048
-
Body mass index before and after breast cancer diagnosis: Associations with all-cause, breast cancer, and cardiovascular disease mortality
-
et al.
-
Nichols HB, Trentham-Dietz A, Egan KM, et al. Body mass index before and after breast cancer diagnosis: associations with all-cause, breast cancer, and cardiovascular disease mortality. Cancer Epidemiol Biomarkers Prev 2009; 18: 1403-9.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 1403-1409
-
-
Nichols, H.B.1
Trentham-Dietz, A.2
Egan, K.M.3
-
10
-
-
78650969715
-
Effect of obesity on survival of women with breast cancer: Systematic review and meta-analysis
-
Protani M, Coory M, Martin JH,. Effect of obesity on survival of women with breast cancer: systematic review and meta-analysis. Breast Cancer Res Treat 2010; 123: 627-35.
-
(2010)
Breast Cancer Res Treat
, vol.123
, pp. 627-635
-
-
Protani, M.1
Coory, M.2
Martin, J.H.3
-
11
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
et al.
-
Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-32.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
-
13
-
-
84859985179
-
The multifactorial role of leptin in driving the breast cancer microenvironment
-
Ando S, Catalano S,. The multifactorial role of leptin in driving the breast cancer microenvironment. Nat Rev Endocrinol 2011; 8: 263-75.
-
(2011)
Nat Rev Endocrinol
, vol.8
, pp. 263-275
-
-
Ando, S.1
Catalano, S.2
-
14
-
-
12244313739
-
Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumors
-
et al.
-
Cleary MP, Phillips FC, Getzin SC, et al. Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumors. Breast Cancer Res Treat 2003; 77: 205-15.
-
(2003)
Breast Cancer Res Treat
, vol.77
, pp. 205-215
-
-
Cleary, M.P.1
Phillips, F.C.2
Getzin, S.C.3
-
15
-
-
0742287956
-
Leptin receptor-deficient MMTV-TGF-alpha/Lepr(db)Lepr(db) female mice do not develop oncogene-induced mammary tumors
-
et al. (Maywood).
-
Cleary MP, Juneja SC, Phillips FC, et al. Leptin receptor-deficient MMTV-TGF-alpha/Lepr(db)Lepr(db) female mice do not develop oncogene-induced mammary tumors. Exp Biol Med (Maywood) 2004; 229: 182-93.
-
(2004)
Exp Biol Med
, vol.229
, pp. 182-193
-
-
Cleary, M.P.1
Juneja, S.C.2
Phillips, F.C.3
-
16
-
-
84884230665
-
Potential role of leptin signaling in DMBA-induced mammary tumors by non-responsive C57BL/6J mice fed a high-fat diet
-
et al.
-
Gillespie C, Quarshie A, Penichet M, et al. Potential role of leptin signaling in DMBA-induced mammary tumors by non-responsive C57BL/6J mice fed a high-fat diet. J Carcinogene Mutagene 2012; 3: 2.
-
(2012)
J Carcinogene Mutagene
, vol.3
, pp. 2
-
-
Gillespie, C.1
Quarshie, A.2
Penichet, M.3
-
17
-
-
33748751983
-
Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)
-
et al.
-
Gonzalez RR, Cherfils S, Escobar M, et al. Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2). J Biol Chem 2006 281: 26320-8.
-
(2006)
J Biol Chem
, vol.281
, pp. 26320-26328
-
-
Gonzalez, R.R.1
Cherfils, S.2
Escobar, M.3
-
18
-
-
70349741579
-
Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer
-
et al.
-
Rene Gonzalez R, Watters A, Xu Y, et al. Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer. Breast Cancer Res 2009; 11: R36.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Rene Gonzalez, R.1
Watters, A.2
Xu, Y.3
-
19
-
-
33745106287
-
Molecular links between obesity and breast cancer
-
Lorincz AM, Sukumar S,. Molecular links between obesity and breast cancer. Endocr Relat Cancer 2006; 13: 279-92.
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 279-292
-
-
Lorincz, A.M.1
Sukumar, S.2
-
20
-
-
79959570695
-
Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer
-
Guo S, Gonzalez-Perez RR,. Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer. PLoS One 2011; 6: e21467.
-
(2011)
PLoS One
, vol.6
-
-
Guo, S.1
Gonzalez-Perez, R.R.2
-
21
-
-
27944466909
-
Studies in a tumor spectrum. I. Comparison of the action of methylbis(2-chloroethyl)amine and 3-bis(2-chloroethyl)aminomethyl-4- methoxymethyl-5-hydroxy-6-methylpyridine on the growth of a variety of mouse and rat tumors
-
Sugiura K, Stock CC,. Studies in a tumor spectrum. I. Comparison of the action of methylbis(2-chloroethyl)amine and 3-bis(2-chloroethyl)aminomethyl-4- methoxymethyl-5-hydroxy-6-methylpyridine on the growth of a variety of mouse and rat tumors. Cancer 1952; 5: 382-402.
-
(1952)
Cancer
, vol.5
, pp. 382-402
-
-
Sugiura, K.1
Stock, C.C.2
-
22
-
-
0042706427
-
A peptide derived from the human leptin molecule is a potent inhibitor of the leptin receptor function in rabbit endometrial cells
-
Gonzalez RR, Leavis P,. A peptide derived from the human leptin molecule is a potent inhibitor of the leptin receptor function in rabbit endometrial cells. Endocrine 2003; 21: 185-95.
-
(2003)
Endocrine
, vol.21
, pp. 185-195
-
-
Gonzalez, R.R.1
Leavis, P.2
-
23
-
-
0028088509
-
Site directed mutagenesis study on DNA binding regions of the mouse homologue of Suppressor of Hairless, RBP-J kappa
-
et al.
-
Chung CN, Hamaguchi Y, Honjo T, et al. Site directed mutagenesis study on DNA binding regions of the mouse homologue of Suppressor of Hairless, RBP-J kappa. Nucleic Acids Res 1994; 22: 2938-44.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 2938-2944
-
-
Chung, C.N.1
Hamaguchi, Y.2
Honjo, T.3
-
24
-
-
84892608495
-
-
Centers for Disease Control and Prevention (CDC), USA. Obesity Statistics, 2013
-
Centers for Disease Control and Prevention (CDC), USA. Obesity Statistics, 2013. Available at: http://www.cdc.gov/obesity/data/adult.html, 2013.
-
(2013)
-
-
-
26
-
-
0037464510
-
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S
-
et al.
-
Calle EE, Rodriguez C, Walker-Thurmond K, et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. New Engl J Med 2003; 348: 1625-38.
-
(2003)
Adults. New Engl J Med
, vol.348
, pp. 1625-1638
-
-
Calle, E.E.1
Rodriguez, C.2
Walker-Thurmond, K.3
-
27
-
-
0035880693
-
Relation of body mass index to tumor markers and survival among young women with invasive ductal breast carcinoma
-
et al.
-
Daling JR, Malone KE, Doody DR, et al. Relation of body mass index to tumor markers and survival among young women with invasive ductal breast carcinoma. Cancer 2001; 92: 720-9.
-
(2001)
Cancer
, vol.92
, pp. 720-729
-
-
Daling, J.R.1
Malone, K.E.2
Doody, D.R.3
-
29
-
-
79957896666
-
Sixteen years and counting: An update on leptin in energy balance
-
Gautron L, Elmquist J,. Sixteen years and counting: an update on leptin in energy balance. J Clin Invest 2011; 121: 2087-93.
-
(2011)
J Clin Invest
, vol.121
, pp. 2087-2093
-
-
Gautron, L.1
Elmquist, J.2
-
30
-
-
78951481235
-
Role of Notch and its oncogenic signaling crosstalk in breast cancer
-
Guo S, Liu M, Gonzalez-Perez RR,. Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim Biophys Acta 2011; 1815: 197-213.
-
(2011)
Biochim Biophys Acta
, vol.1815
, pp. 197-213
-
-
Guo, S.1
Liu, M.2
Gonzalez-Perez, R.R.3
-
31
-
-
0031010408
-
Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
-
et al.
-
Fei H, Okano HJ, Li C, et al. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci USA 1997; 94: 7001-5.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7001-7005
-
-
Fei, H.1
Okano, H.J.2
Li, C.3
-
32
-
-
84884271124
-
Leptin induces Notch in endothelial cells: Role of VEGFR-2 transactivation
-
Lanier V, Gillespie C, McGlothen T, et al. Leptin induces Notch in endothelial cells: role of VEGFR-2 transactivation. Cancer Res 2012; 72: (suppl 1).
-
(2012)
Cancer Res
, vol.72
, Issue.SUPPL. 1
-
-
Lanier, V.1
Gillespie, C.2
McGlothen, T.3
-
33
-
-
14244269366
-
The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer
-
Parr C, Watkins G, Jiang WG,. The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer. Int J Mol Med 2004; 14: 779-86.
-
(2004)
Int J Mol Med
, vol.14
, pp. 779-786
-
-
Parr, C.1
Watkins, G.2
Jiang, W.G.3
-
34
-
-
51649090695
-
JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer
-
et al.
-
Reedijk M, Pinnaduwage D, Dickson BC, et al. JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer. Breast Cancer Res Treat 2008; 111: 439-48.
-
(2008)
Breast Cancer Res Treat
, vol.111
, pp. 439-448
-
-
Reedijk, M.1
Pinnaduwage, D.2
Dickson, B.C.3
-
35
-
-
0019996610
-
Accelerated appearance of chemically induced mammary carcinomas in obese yellow (Avy/A) (BALB/c X VY) F1 hybrid mice
-
et al.
-
Wolff GL, Kodell RL, Cameron AM, et al. Accelerated appearance of chemically induced mammary carcinomas in obese yellow (Avy/A) (BALB/c X VY) F1 hybrid mice. J Toxicol Environ Health 1982; 10: 131-42.
-
(1982)
J Toxicol Environ Health
, vol.10
, pp. 131-142
-
-
Wolff, G.L.1
Kodell, R.L.2
Cameron, A.M.3
-
36
-
-
0021999065
-
The role of high levels of dietary fat in 7,12-dimethylbenzanthracene- induced mouse mammary tumorigenesis: Lack of an effect on lipid peroxidation
-
et al.
-
Lane HW, Butel JS, Howard C, et al. The role of high levels of dietary fat in 7,12-dimethylbenzanthracene-induced mouse mammary tumorigenesis: lack of an effect on lipid peroxidation. Carcinogenesis 1985; 6: 403-7.
-
(1985)
Carcinogenesis
, vol.6
, pp. 403-407
-
-
Lane, H.W.1
Butel, J.S.2
Howard, C.3
-
37
-
-
63449116164
-
HER-2, notch, and breast cancer stem cells: Targeting an axis of evil
-
Korkaya H, Wicha MS,. HER-2, notch, and breast cancer stem cells: targeting an axis of evil. Clin Cancer Res 2009; 15: 1845-7.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1845-1847
-
-
Korkaya, H.1
Wicha, M.S.2
-
38
-
-
13244298130
-
Self-renewal and solid-tumor stem cells
-
Clarke MF,. Self-renewal and solid-tumor stem cells. Biol Blood Marrow Transplant 2005; 11: 14-6.
-
(2005)
Biol Blood Marrow Transplant
, vol.11
, pp. 14-16
-
-
Clarke, M.F.1
-
39
-
-
79952370202
-
The cancer stem cell: Premises, promises and challenges
-
Clevers H,. The cancer stem cell: premises, promises and challenges. Nat Med 2011; 17: 313-9.
-
(2011)
Nat Med
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
40
-
-
78649466892
-
Targeting Notch signaling pathway to overcome drug resistance for cancer therapy
-
et al.
-
Wang Z, Li Y, Ahmad A, et al. Targeting Notch signaling pathway to overcome drug resistance for cancer therapy. Biochim Biophys Acta 2010; 1806: 258-67.
-
(2010)
Biochim Biophys Acta
, vol.1806
, pp. 258-267
-
-
Wang, Z.1
Li, Y.2
Ahmad, A.3
-
41
-
-
79961173038
-
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner
-
et al.
-
Pajvani UB, Shawber CJ, Samuel VT, et al. Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner. Nat Med 2011; 17: 961-7.
-
(2011)
Nat Med
, vol.17
, pp. 961-967
-
-
Pajvani, U.B.1
Shawber, C.J.2
Samuel, V.T.3
-
42
-
-
77951880179
-
Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway
-
et al.
-
Eliasz S, Liang S, Chen Y, et al. Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway. Oncogene 2010; 29: 2488-98.
-
(2010)
Oncogene
, vol.29
, pp. 2488-2498
-
-
Eliasz, S.1
Liang, S.2
Chen, Y.3
-
43
-
-
79955136974
-
Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells
-
et al.
-
Garonna E, Botham KM, Birdsey GM, et al. Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells. Plos one 2011; 6: e18823.
-
(2011)
Plos One
, vol.6
-
-
Garonna, E.1
Botham, K.M.2
Birdsey, G.M.3
-
44
-
-
77956380733
-
Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells
-
et al.
-
Bartucci M, Svensson S, Ricci-Vitiani L, et al. Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells. Endocr Relat Cancer 2010; 17: 823-33.
-
(2010)
Endocr Relat Cancer
, vol.17
, pp. 823-833
-
-
Bartucci, M.1
Svensson, S.2
Ricci-Vitiani, L.3
|