Continuing antiplatelet therapy before cardiac surgery with cardiopulmonary bypass: A meta-analysis on the need for reexploration and major outcomes

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 28, Issue 1, 2014, Pages 90-97

  Guay, Joanne ^a   Andrew Ochroch, E ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

antiplatelets; blood loss; cardiac surgery; cardiopulmonary bypass; death; fresh frozen plasma; myocardial infarction; platelets; red blood cells; reexploration; stroke

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; APROTININ; CLOPIDOGREL; DESMOPRESSIN ACETATE; DIPYRIDAMOLE; FRESH FROZEN PLASMA; PLACEBO;

ACUTE CORONARY SYNDROME; ADVERSE OUTCOME; ANTICOAGULANT THERAPY; ARTICLE; CARDIOPULMONARY BYPASS; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; COCHRANE LIBRARY; EMBASE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART SURGERY; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MEDIASTINITIS; MEDLINE; META ANALYSIS; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; OUTCOME ASSESSMENT; POSITIVE END EXPIRATORY PRESSURE; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REOPERATION; SEPSIS; SYSTEMATIC REVIEW; THROMBOCYTE FUNCTION; WOUND INFECTION;

ANTIPLATELETS; BLOOD LOSS; CARDIAC SURGERY; CARDIOPULMONARY BYPASS; DEATH; FRESH FROZEN PLASMA; MYOCARDIAL INFARCTION; PLATELETS; RED BLOOD CELLS; REEXPLORATION; STROKE;

BLOOD LOSS, SURGICAL; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; CORONARY ARTERY BYPASS; HUMANS; PLATELET AGGREGATION INHIBITORS; REOPERATION; TREATMENT OUTCOME;

EID: 84892599355     PISSN: 10530770     EISSN: 15328422     Source Type: Journal    
DOI: 10.1053/j.jvca.2013.03.013     Document Type: Article

References (29)

1. L.T. Newsome, R.S. Weller, and J.C. Gerancher et al. Coronary artery stents: II. Perioperative considerations and management Anesth Analg 107 2008 570 590
2. M.B. Leon, D.S. Baim, and J.J. Popma et al. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators N Engl J Med 339 1998 1665 1671
3. D.J. Angiolillo, M.S. Firstenberg, and M.J. Price et al. Bridging antiplatelet therapy with cangrelor in patients undergoing cardiac surgery: A randomized controlled trial JAMA 307 2012 265 274
4. E. Akowuah, V. Shrivastava, and B. Jamnadas et al. Comparison of two strategies for the management of antiplatelet therapy during urgent surgery Ann Thorac Surg 80 2005 149 152
5. J.H. Chesebro, I.P. Clements, and V. Fuster et al. A platelet-inhibitor- drug trial in coronary-artery bypass operations: Benefit of perioperative dipyridamole and aspirin therapy on early postoperative vein-graft patency N Engl J Med 307 1982 73 78
6. V.A. Ferraris, S.P. Ferraris, and F.C. Lough et al. Preoperative aspirin ingestion increases operative blood loss after coronary artery bypass grafting Ann Thorac Surg 45 1988 71 74
7. J.K. Fuller, and J.G. Copeland Does short-term pre-operative aspirin in coronary bypass patients increase post-operative bleeding? Vasc Endovasc Surg 19 1985 174 178
8. M.H. Ghaffarinejad, A.F. Fazelifar, and S.M. Shirvani et al. The effect of preoperative aspirin use on postoperative bleeding and perioperative myocardial infarction in patients undergoing coronary artery bypass surgery Cardiol J 14 2007 453 457
9. S. Goldman, J. Copeland, and T. Mortiz et al. Improvement in early saphenous vein graft patency after coronary artery bypass surgery with antiplatelet therapy: Results of a Veterans Administration Cooperative Study Circulation 77 1988 1324 1332
10. S. Goldman, J. Copeland, and T. Moritz et al. Starting aspirin therapy after operation: Effects on early graft patency Circulation 84 1991 520 526
11. B.E.F. Hockings, M.A. Ireland, and K.F. Gotch-Martin et al. Placebo controlled trial of enteric coated aspirin in coronary bypass graft patients Med J Aust 159 1993 376 378
12. P. Kallis, J.A. Tooze, and S. Talbot et al. Pre-operative aspirin decreases platelet aggregation and increases post-operative blood loss: A prospective, randomized, placebo controlled, double-blind clinical trial in 100 patients with chronic stable angina Eur J Cardiothorac Surg 8 1994 404 409
13. S.V. Karwande, B.B. Weksler, and W.A. Gay Jr et al. Effect of preoperative antiplatelet drugs on vascular prostacyclin synthesis Ann Thorac Surg 43 1987 318 322
14. K.H. Teoh, G.T. Christakis, and R.D. Weisel et al. Dipyridamole preserved platelets and reduced blood loss after cardiopulmonary bypass J Thorac Cardiovasc Surg 96 1988 332 341
15. J. van der Meer, H.L. Hillege, and G.J. Kootstra et al. Prevention of one-year vein-graft occlusion after aortocoronary-bypass surgery: A comparison of low-dose aspirin, low-dose aspirin plus dipyridamole, and oral anticoagulants. The CABADAS Research Group of the Interuniversity Cardiology Institute of The Netherlands Lancet 342 1993 257 264
16. R.H. Mehta, S. Sheng, and S.M. O'Brien et al. Society of Thoracic Surgeons National Cardiac Surgery Database Investigators. Reoperation for bleeding in patients undergoing coronary artery bypass surgery: Incidence, risk factors, time trends, and outcomes Circ Cardiovasc Qual Outcomes 2 2009 583 590
17. W. Burger, J.M. Chemnitius, and G.D. Kneissl et al. Low-dose aspirin for secondary cardiovascular prevention - cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - review and meta-analysis J Intern Med 257 2005 399 414
18. Pulmonary Embolism Prevention (PEP) Trial Collaborative Group Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial Lancet 355 2000 1295 1302
19. L. Ardekian, R. Gaspar, and M. Peled et al. Does low-dose aspirin therapy complicate oral surgical procedures? J Am Dent Assoc 131 2000 331 335
20. B. Lindblad, N.H. Persson, and R. Takolander et al. Does low-dose acetylsalicylic acid prevent stroke after carotid surgery? A double-blind, placebo-controlled randomized trial Stroke 24 1993 1125 1128
21. C. McCollum, C. Alexander, and G. Kenchington et al. Antiplatelet drugs in femoropopliteal vein bypasses: A multicenter trial J Vasc Surg 13 1991 150 162
22. D.A. Payne, C.I. Jones, and P.D. Hayes et al. Beneficial effects of clopidogrel combined with aspirin in reducing cerebral emboli in patients undergoing carotid endarterectomy Circulation 109 2004 1476 1481
23. A.V. Thurston, and S.L. Briant Aspirin and post-prostatectomy hemorrhage Br J Urol 71 1993 574 576
24. A.I. Qureshi, M. Saad, and O.O. Zaidat et al. Intracerebral hemorrhages associated with neurointerventional procedures using a combination of antithrombotic agents including abciximab Stroke 33 2002 1916 1919
25. M. Borenstein, L.V. Hedges, and J.P.T. Higgins et al. Introduction to Meta-analysis 2009 2009 Wiley Padstow, Cornwall 45 49
26. N.L. Pace Research methods for meta-analyses Best Pract Res Clin Anaesthesiol 25 2011 523 533
27. Ferraris VA, Brown JR, Despotis GJ, et al. 2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines. Ann Thorac Surg 91:944-982, 2011
28. D. Henry, P. Carless, and D. Fergusson et al. The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: A meta-analysis CMAJ 180 2009 183 193
29. D.R. McIlroy, P.S. Myles, and L.E. Phillips et al. Antifibrinolytics in cardiac surgical patients receiving aspirin: A systematic review and meta-analysis Br J Anaesth 102 2009 168 178