Cost-effectiveness in the diagnosis of tuberculosis: Choices in developing countries

Journal of Infection in Developing Countries

Volumn 8, Issue 1, 2014, Pages 24-38

  Molicotti, Paola ^a   Bua, Alessandra ^a   Zanetti, Stefania ^a  

^a UNIVERSITY OF SASSARI   (Italy)

Author keywords

Diagnosis; M. tuberculosis; Tuberculosis

Indexed keywords

CLINICAL LABORATORY TECHNIQUES; COST-BENEFIT ANALYSIS; DEVELOPING COUNTRIES; DIAGNOSTIC TESTS, ROUTINE; HUMANS; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS;

EID: 84892573778     PISSN: 20366590     EISSN: 19722680     Source Type: Journal    
DOI: 10.3855/jidc.3295     Document Type: Review

References (60)

1. Watt CJ, Hosseini SM, Lonnroth K, Williams BG, Dye C (2009) The global epidemiology of tuberculosis. In Schaaf S, Zumla A, editors. Tuberculosis: a comprehensive clinical reference. Philadelphia, PA: Saunders. 17-27.
2. Waddell T, editor (2010) World Health Statistics. Geneva: World Health Organization Global tuberculosis control: WHO report 2011.
3. Zanetti S, Sechi LA, Molicotti P, Delogu G, Rubino S (2013) In honor of Professor Giovanni Fadda: a fighter against tuberculosis. J Infect Dev Ctries 7: 159-160.
4. Taki-Eddin L, Monem F (2012) Utility of an interferon-gamma release assay as a potential diagnostic aid for active pulmonary tuberculosis. J Infect Dev Ctries 6: 67-72.
5. Bua A, Molicotti P, Ruggeri M, Madeddu G, Ferrandu G, Mura MS, Zanetti S (2011) Interferon-γ release assay in people infected with immunodeficiency virus. Clin Microbio Infect 17: 402-404.
6. Casas S, Andreu A, Juanola X, Bordas X, Alcaide F, Moure R, Anibarro L, Cuchí E, Esteve M, Ortiz V, Guerra MR, Rodríguez J, Reina D, Salvador G, Guardiola J, Surís X, Pascual MA, Martí C, Martínez-Lacasa X, Cuquet J, Gonzalez L, Santin M (2011) Diagnosis of tuberculosis infection by tuberculin skin test and a whole-blood interferon-γ release assay in patients considered for anti-tumor necrosis factor-α therapy. Diagn Microbiol Infect Dis 71: 57-65.
7. Molicotti P, Bua A, Mela G, Olmeo P, Delogu R, Ortu S, Sechi LA, Zanetti S (2008) Performance of QuantiFERON-TB testing in a tuberculosis outbreak at a primary school. J Pediatr 152: 585-586.
8. Metcalfe JZ, Everett CK, Steingart KR, Cattamanchi A, Huang L, Hopewell PC, Pai M (2011) Interferon-{gamma} Release Assays for Active Pulmonary Tuberculosis Diagnosis in Adults in Low-and Middle-Income Countries: Systematic Review and Meta-analysis. J Infect Dis 204 Suppl 4: S1120-1129.
9. Ferroni A, Vu-Thien H, Lanotte P, Le Bourgeois M, Sermet-Gaudelus I, Fauroux B, Marchand S, Varaigne F, Berche P, Gaillard JL, Offredo C (2006) Value of the chlorhexidine decontamination method for recovery of nontuberculous mycobacteria from sputum samples of patients with cystic fibrosis. J Clin Microbiol 44: 2237-2239.
10. Ardito F, Sanguinetti M, Sechi LA, Posteraro B, Masucci L, Fadda G, Zanetti S (2000) Comparison of the mycobacteria growth indicator tube with radiometric and solid culture for isolation of mycobateria from clinical specimens and susceptibility testing of mycobacterium tuberculosis. New Microbiol 23: 151-158.
11. Ardito F, Posteraro B, Sanguinetti M, Zanetti S, Fadda G (2001) Evaluation of BACTEC Mycobacteria Growth Indicator Tube (MGIT 960) Automated System for Drug Susceptibility Testing of Mycobacterium tuberculosis. J Clin Microbiol 39: 4440-4444.
12. Parrich NM, Carroll KC (2010) The role of the clinical mycobacteriology laboratory in the diagnosis and management of tuberculosis in low prevalence setting. J Clin Microbiol 49: 772-776.
13. Palomino JC, Martin A, Von Groll A, Portaeles F (2008) Rapid culture-based methods for drug-resistance detection in Mycobacterium tuberculosis. J Microbiol Met 75: 161-166.
14. Kidenya BR, Kabangila R, Peck RN, Mshana E, Webster LE, Koenig SP, Johnson Jr WD, Fitzgerald DW (2013) Early and Efficient Detection of Mycobacterium tuberculosis in Sputum by Microscopic Observation of Broth Cultures. PlosOne 8: e57527.
15. Bwanga F, Hoffner S, Haile M, Joloba M (2009) Direct susceptibility testing for multi drug resistant tuberculosis: a meta-analysis. BMC Infect Dis 9: 67.
16. Chaiyasirinroje B, Aung MN, Moolphate Y, Rienthong S, Rienthong D, Nampaisa O, Nedsuwan S, Sangehum W, Suriyon N, Mitarai S, Yamada N (2012) Prospective evaluation of simply modified MODS assay: an effective tool for TB diagnosis and detection of MDR-TB. Infect Drug Resist 5: 79-86.
17. Rasslan O, Hafez SF, Hashem M, Ahmed OI, Faramawy MAS, Khater WS, Saleh DA, Mohamed MI, Khalifa MAM, Shoukry FA, El-Moghazy EH (2012) Microscopic observation drug susceptibility assay in the diagnosis of multidrug-resistant tuberculosis. Int J Tuberc Lung Dis 16: 941-946.
18. Makamure B, Mhaka J, Makumbirofa S, Mutetwa R, Mupfumi L, Mason P, Metcalfe JZ (2013) Microscopic-Observation Drug-Susceptibility Assay for the Diagnosis of Drug-Resistant Tuberculosis in Harare, Zimbabwe. PlosONE 8: e55872.
19. Dixit P, Singh U, Sharma P, Jain A (2012) Evaluation of nitrate reduction assay, resazurin microtiter assay and microscopic observation drug susceptibility assay for first line antitubercular drug susceptibility testing of clinical isolates of M. tuberculosis. Journal of Microbiological Methods 88: 122-126.
20. Sperhacke RD, Mello FC, Zaha A, Kritski A, Rosetti ML (2004) Detection of Mycobacterium tuberculosis by a polymerase chain reaction colorimetric dot-blot assay. Int J Tuberc Lung D 8: 312-317.
21. Sechi LA, Pinna MP, Sanna A, Pirina P, Ginesu F, Saba F, Aceti A, Turrini F, Zanetti S, Fadda G (1997) Detection of Mycobacterium tuberculosis by PCR analysis of urine and other clinical samples from AIDS and non-HIV-infected patients. Mol Cell Probes 11: 281-285.
22. Helb D, Jones M, Story E, Boehme C, Wallace E, Ho K, Kop J, Owens MR, Rodgers R, Banada P, Safi H, Blakemore R, Lan NT, Jones-López EC, Levi M, Burday M, Ayakaka I, Mugerwa RD, McMillan B, Winn-Deen E, Christel L, Dailey P, Perkins MD, Persing DH, Alland D (2010) Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology. J Clin Microbiol 48: 229-237.
23. Blakemore R, Story E, Helb D, Kop J, Banada P, Owens MR, Chakravorty S, Jones M, Alland D (2010) Evaluation of the analytical performance of the Xpert MTB/RIF assay. J Clin Microbiol 48: 2495-2501.
24. Boehme CC, Nicol MP, Nabeta P, Michael JS, Gotuzzo E, Tahirli R, Gler MT, Blakemore R, Worodria W, Gray C, Huang L, Caceres T, Mehdiyev R, Raymond L, Whitelaw A, Sagadevan K, Alexander H, Albert H, Cobelens F, Cox H, Alland D, Perkins MD (2011) Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicenter implementation study. Lancet 377:1495-1505.
25. Lawn S, Nicol M (2011) Xpert MTB/RIF assay: development, evaluation and implementation of a new rapid molecular diagnostic for tuberculosis and rifampicin resistance. Future Microbiol 6: 1067-1082.
26. Marlowe EM, Novak-Weekley SM, Cumpio J, Sharp SE, Momeny MA, Babst A, Carlson JS, Kawamura M, Pandori M (2011) Evaluation of the Cepheid Xpert MTB/RIF assay for direct detection of Mycobacterium tuberculosis complex in respiratory specimens. J Clin Microbiol 49: 1621-1623.
27. Lawn SD, Brooks SV, Kranzer K, Nicol MP, Whitelaw A, Vogt M, Bekker LG, Wood R (2011) Screening for HIV-associated tuberculosis and rifampicin resistance before antiretroviral therapy using the Xpert MTB/RIF assay: a prospective study. PLoS Med 8: e1001067.
28. World Health Organization (2011) Rapid implementation of the Xpert MTB/ RIF diagnostic test: technical and operational "How-to"; practical considerations. Geneva: World Health Organization.
29. World Health Organization (2010) Treatment of tuberculosis: Guidelines-Fourth edition. Geneva: World Health Organization, http://whqlibdoc.who.int/ publications/2010/9789241547833_eng.pdf. Accessed 30 Nov, 2010.
30. Ma Z, Lienhardt C, McIlleron H, Nunn AJ, Wang X (2010) Global tuberculosis drug development pipeline: the need and the reality. Lancet 375: 2100-2109.
31. World Health Organization (2009) Report of the 9th meeting: WHO strategic and technical advisory group for tuberculosis. Geneva: World Health Organization.
32. Won-Jung Koh MD, Yousang Ko MD, Chang-Ki Kim MD, Kyung Sun Park MD, Nam Yong Lee MD (2012) Rapid Diagnosis of Tuberculosis and Multidrug Resistance Using a MGIT 960 System. Ann Lab Med 32: 264-269.
33. Lin SY, Desmond E, Bonato D, Gross W, Siddiqi S (2009) Multicenter evalutation of BACTEC MGIT 960 system for second-line drug susceptibility testing of Mycobacterium tuberculosis complex. J Clin Microbiol 47: 3630-3634.
34. Mitarai S, Kato S, Ogata H, Aono A, Chikamatsu K, Mizuno K Toyota E, Sejimo A, Suzuki K, Yoshida S, Saito T, Moriya A, Fujita A, Sato S, Matsumoto T, Ano H, Suetake T, Kondo Y, Kirikae T, Mori T (2012) Comprehensive multicenter evalutation of a new line probe assay kit for identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis. J Clin Microbiol 50: 884-890.
35. Kiet VS, Lan NT, An DD, Dung NH, Hoa Dv, van Vinh Chau N, Chinh NT, Farrar J, Caws M (2010) Evalutation of the MTBDRsl test for detection of second-line-drug resistance in Mycobacterium tuberculosis. J Clin Microbiol 48: 2934-2939.
36. Dang TM, Nguyen TN, Wolbers M, Vo SK, Hoang TT, Nguyen HD, To MH, Vuong MB, Nguyen TP, Tran VQ, Nguyen TB, Vo TH, Nguyen Tn, Dai VH, Phan TH, Nguyen HD, Farrar J, Caws M (2012). Evalutation of microscopic observation drug susceptibility assay for diagnosis of multidrug resistance tuberculosis in Viet Nam. BMC Infect Dis 12: 49.
37. Satti L, Ikram A, Palomino JC, Martin A, Khan FA (2013) Field evaluation of the direct detection of multidrug resistant Mycobacterium tuberculosis by nitrate reductase assay on 7H11 agar. Tuberculosis 93: 308-311.
38. Ramos E, Fissette K, de Rijk P, Palomino JC, Martin A (2012) Integrated detection of multi-and extensively drug-resistant tuberculosis using the nitrate reductase assay. Int J Tuberc Lung Dis 16: 110-113.
39. Luo T, Jiang L, Sun W, Fu G, Mei J, Gao Q (2011). Multiplex Real-Time PCR Melting Curve Assay To Detect Drug-Resistant Mutations of Mycobacterium tuberculosis. J Clin Microbiol: 3132-3138.
40. Liu Q, Luo T, Li J, Mei J, Gao Q (2013) Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction. J Antimicrob Chemother 68: 1097-1103.
41. Engstrom A, Morcillo N, Imperiale B, Hoffner SE, Jureen P (2012) Detection of First-and Second-line Drug Resistance in Mycobacterium tuberculosis Clinical isolates by Pyrosequencing. J Clin Microbiol 50: 2026-2033.
42. Aragon LM, Navarro F, Heisen V, Garrigo M, espanol M, Coll P (2006) Rapid detection of specific gene mutations associated with isoniazid or rifampicin resistance in Mycobacterium tuberculosis clinical isolates using non-fluorescent low-density DNA microarrays. Journal of Antimicrobial Chemotherapy 57: 825-831.
43. Zhang Z, Li L, Luo F, Cheng P, Wu F, Wu Z, Hou T, Zhong M, Xu J (2012) Rapid and accurate detection of RMP-and INH-resistant Mycobacterium tuberculosis in spinal tuberculosis specimens by CapitalBio™ DNA microarray: A prospective validation study. BMC Infectious Diseases 12: 303.
44. Minion J, Leung E, Talbot E, Dheda K, Pai M, Menzies D (2011) Diagnosing tuberculosis with urine lipoarabinomannan: systematic review and meta-analysis. Eur Respir J 38: 1398-1405.
45. Lawn SD, Edwards DJ, Kranzer K, Vogt M, Bekker LG, Wood R (2009) Urine lipoarabinomannan assay for tuberculosis screening before antiretroviral therapy diagnostic yield and association with immune reconstitution disease. AIDS 23: 1875-1880.
46. Lawn SD, Kerkhoff AD, Vogt M, Wood R (2011) Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV associated pulmonary tuberculosis before antiretroviral therapy: a descriptive study. Lancet Infect Dis 12: 201-209.
47. Lawn SD, Kerkhoff AD, Vogt M, Wood R (2012) Clinical significance of lipoarabinomannan detection in urine using a low-cost point-of-care diagnostic assay for HIV-associated tuberculosis. AIDS 26: 1635-1643.
48. Muchwa M, Akol J, Etwom A, Morgan K, Orikiriza P, Mumbowa F, Odong PR, Kateete DP, Eisenach KD, Joloba ML (2012) Evaluation of Capilia TB assay for rapid identification of Mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures. BMC Research Notes 5: 44.
49. Muyoyeta M, de Haas PE, Mueller DH, van Helden PD, Mwenge L, Schaap A, Kruger C, Gey van Pittius NC, Lawrence K, Beyers N, Godfrey-Faussett P, Ayles H (2010) Evalutation of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis infections in Zambia and South Africa. J Clin Microbiol 48: 3773-3775.
50. Martin A, Bombeeck D, Fissette K, Pim de Rijk, Hernández-Neuta I, Del Portillo P, Palomino JC (2011) Evaluation of the BD MGIT TBc Identification Test (TBc ID), a rapid chromatographic immunoassay for the detection of Mycobacterium tuberculosis complex from liquid culture. Journal of Microbiological Methods 84: 255-257.
51. Po-Liang Lu, Yuan-Chieh Yang, Su Chiao Huang, Yi-Shan Jenh, Yao-Cheng Lin, Hsin-Hui Huang, and Tsung Chain Chang (2011) Evaluation of the Bactec MGIT 960 System in Combination with the MGIT TBc Identification Test for Detection of Mycobacterium tuberculosis Complex in Respiratory Specimens. J of Clin Microbiol 49: 2290-2292.
52. Poling A (2011) Tuberculosis detection by giant African pouched rats. The Behavior Analyst 34: 47-54.
53. Weetjens BJ, Mgode GF, Machang'u RS, Kazwala R, Mfinanga G, Lwilla F, Cox C, Jubitana M, Kanyagha H, Mtandu R, Kahwa A, Mwessongo J, Makingi G, Mfaume S, Van Steenberge J, Beyene NW, Billet M, Verhagen R (2009) African pouched rats for the detection of pulmonary tuberculosis in sputum samples. Int J Tuberc Lung Dis 13: 1-7.
54. Poling A, Weetjens BJ, Cox C, Mgode G, Jubitana M, Kazwala R, Mfinanga GS, Huis In 't Veld D (2010) Using giant African pouched rats to detect tuberculosis in human sputum samples: 2009 findings. Am J Trop Med Hyg 83: 1308-1310.
55. Mgode GF, Weetjens BJ, Cox C, Jubitana M, Machang'u RS, Lazar D, Weiner J, Van Geertruyden JP, Kaufmann SH (2012) Ability of Cricetomys rats to detect Mycobacterium tuberculosis and discriminate it from other microorganisms. Tuberculosis (Edinb) 92: 182-186.
56. Siddiqi SH and Rüsch-Gerdes S (2006) MGIT procedure manual. Foundation for Innovative New Diagnostics, Geneva, Switzerland.
57. Chihota VN, Grant AD, Fielding K, Ndibongo B, van Zyl A, Muirhead D (2010) Liquid vs solid culture for tuberculosis: performance and cost in a resource-constrained setting. Int Tuberc Lung Dis 14: 1024-1031.
58. Dowdy DW, Lourenco MC, Cavalcante SC, Saraceni V, King B, Golub JE, Bishai D, Durovni B, Chaisson RE, Dorman SE (2008) Impact and cost-effectiveness of culture for diagnosis of tuberculosis in HIV-infected Brazilian adults. PLoS ONE 3: 12:e4057.
59. Kidenya BR, Kabangila R, Peck RN, Mshana SE, Webster LE, Koenig SE, Johnson Jr WD, Fitzgerald DW (2013) Early and Efficient Detection of Mycobacterium tuberculosis in Sputum by Microscopic Observation of Broth Cultures. PLoS ONE 8: e57527.
60. Foundation for Innovative New Diagnostics (FIND). Negotiated prices for Xpert MTB/RIF and FIND country list, August 2012. http://www.find diagnostics.org/about/what_we_do/successes/findnegotiated-prices/xpert_mtb_rif.html. Accessed 12 Sep, 2012.