PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-κB

Journal of Hepatology

Volumn 60, Issue 2, 2014, Pages 306-312

  Hou, Jiajie ^a,b   Xia, Yongxiang ^a,b   Jiang, Runqiu ^a,b   Chen, Dianyu ^a,b   Xu, Juan ^c   Deng, Lei ^a,b   Huang, Xingxu ^c   Wang, Xuehao ^a,b   Sun, Beicheng ^a,b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Jiangsu Key Laboratory of Molecular Medicine   (China)

^c NANJING UNIVERSITY   (China)

Author keywords

c Src; Hepatic ischemia reperfusion injury; NF B; PTPRO

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXIDE; PROTEIN KINASE P60; PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE O; TUMOR NECROSIS FACTOR ALPHA; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SURGERY; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIVER CELL; LIVER HEMANGIOMA; LIVER ISCHEMIA; LIVER SURGERY; MACROPHAGE; MALE; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REDUCTION; REPERFUSION INJURY; UPREGULATION; WILD TYPE;

C-SRC; HCC; HEPATIC ISCHEMIA REPERFUSION INJURY; HEPATOCELLULAR CARCINOMA; IKK; IL-1Β; INHIBITOR OF NF-ΚB; INTERLEUKIN-1Β; IR; ISCHEMIA REPERFUSION; IΚB; IΚB KINASE; JNK; JUN N-TERMINAL KINASE; KCS; KUPFFER CELLS; NF-ΚB; NUCLEAR FACTOR-ΚB; PHOSPHOTYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE O; PTP; PTPRO; REACTIVE OXYGEN SPECIES; ROS; SHP2; SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION; SRC HOMOLOGY DOMAIN-CONTAINING PHOSPHATASE-2; STAT; TNFΑ; TUMOR NECROSIS FACTOR Α;

ANIMALS; DISEASE MODELS, ANIMAL; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION; HEPATOCYTES; HUMANS; LIVER; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 3; REPERFUSION INJURY; RNA, MESSENGER; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84892541040     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.09.028     Document Type: Article

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