Continuing clopidogrel during elective total hip and knee arthroplasty: Assessment of bleeding risk and adverse outcomes

Journal of Arthroplasty

Volumn 29, Issue 2, 2014, Pages 325-328

  Jacob, Adam K ^a   Hurley, Sean P ^a   Loughran, Sean M ^a   Wetsch, Tyler M ^a   Trousdale, Robert T ^a  

^a MAYO CLINIC   (United States)

Author keywords

Bleeding risk; Clopidogrel; Total hip and knee arthroplasty

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; DALTEPARIN; ENOXAPARIN; FRESH FROZEN PLASMA; HEMOGLOBIN; HEPARIN; WARFARIN;

ADVERSE OUTCOME; AGED; ARTICLE; BLEEDING; BLOOD SALVAGE; BLOOD TRANSFUSION; COHORT ANALYSIS; CONTROLLED STUDY; ELECTIVE SURGERY; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE TRANSFUSION; FEMALE; HOSPITALIZATION; HUMAN; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; OPERATIVE BLOOD LOSS; OUTCOME ASSESSMENT; PERIOPERATIVE PERIOD; REOPERATION; RETROSPECTIVE STUDY; RISK ASSESSMENT; THROMBOCYTE TRANSFUSION; TOTAL HIP PROSTHESIS; TOTAL KNEE REPLACEMENT;

BLEEDING RISK; CLOPIDOGREL; TOTAL HIP AND KNEE ARTHROPLASTY;

AGED; AGED, 80 AND OVER; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; BLOOD TRANSFUSION; FEMALE; HEART DISEASES; HUMANS; MALE; PLATELET AGGREGATION INHIBITORS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SURGICAL PROCEDURES, ELECTIVE; TICLOPIDINE; TREATMENT OUTCOME;

EID: 84892528841     PISSN: 08835403     EISSN: 15328406     Source Type: Journal    
DOI: 10.1016/j.arth.2013.06.008     Document Type: Article

References (16)

1. National Center for Health Statistics. Center for Disease Control, 2011: Discharges with at least one procedure in nonfederal short-stay hospitals, by sex, age, and selected procedures: United States, selected years 1990 through 2009-2010. Accessed on December 27, 2012.
2. Guerin S., Collins C., Kapoor H., et al. Blood transfusion requirement prediction in patients undergoing primary total hip and knee arthroplasty. Transfus Med 2007, 17:37.
3. Fleisher L.A., Beckman J.A., Brown K.A., et al. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Anesth Analg 2008, 106:685.
4. Brown M.J., Long T.R., Brown D.R., et al. Acute coronary syndrome and myocardial infarction after orthopedic surgery in a patient with a recently placed drug-eluting stent. J Clin Anesth 2006, 18:537.
5. Kaluza G.L., Joseph J., Lee J.R., et al. Catastrophic outcomes of noncardiac surgery soon after coronary stenting. J Am Coll Cardiol 2000, 35:1288.
6. Rabbitts J.A., Nuttall G.A., Brown M.J., et al. Cardiac risk of noncardiac surgery after percutaneous coronary intervention with drug-eluting stents. Anesthesiology 2008, 109:596.
7. Grujic D., Martin D. Perioperative clopidogrel is seven days enough?. Am Surg 2009, 75:909.
8. Kang W., Theman T.E., Reed J.F., et al. The effect of preoperative clopidogrel on bleeding after coronary artery bypass surgery. J Surg Educ 2007, 64:88.
9. Maltais S., Perrault L.P., Do Q.B. Effect of clopidogrel on bleeding and transfusions after off-pump coronary artery bypass graft surgery: impact of discontinuation prior to surgery. Eur J Cardio-Thorac Surg 2008, 34:127.
10. Pickard A.S., Becker R.C., Schumock G.T., et al. Clopidogrel-associated bleeding and related complications in patients undergoing coronary artery bypass grafting. Pharmacotherapy 2008, 28:376.
11. Callaghan J.J., Spitzer A.I. Blood management and patient specific transfusion options in total joint replacement surgery. Iowa Orthop J 2000, 20:36.
12. Bierbaum B.E., Callaghan J.J., Galante J.O., et al. An analysis of blood management in patients having a total hip or knee arthroplasty. J Bone Joint Surg Am 1999, 81:2.
13. Rosencher N., Kerkkamp H.E., Macheras G., et al. Orthopedic Surgery Transfusion Hemoglobin European Overview (OSTHEO) study: blood management in elective knee and hip arthroplasty in Europe. Transfusion 2003, 43:459.
14. Oh J.J., Robon M.J., Akers W.S. Optimizing antiplatelet and anticoagulant agents in the perioperative orthopedic surgery patient. Orthopedics 2005, 28:453.
15. Palan J., Odutola A., White S.P. Is clopidogrel stopped prior to hip fracture surgery-A survey of current practice in the United Kingdom. Injury 2007, 38:1279.
16. Lannan K.L., Sahler J., Spinelli S.L., et al. Transfusion immunomodulation-the case for leukoreduced and (perhaps) washed transfusions. Blood Cells Mol Dis 2013, 50:61.