Does presence of squamous and glandular differentiation in urothelial carcinoma of the bladder at cystectomy portend poor prognosis? An intensive case-control analysis

Urologic Oncology: Seminars and Original Investigations

Volumn 32, Issue 2, 2014, Pages 117-127

  Mitra, Anirban P ^a   Bartsch, Claudia C ^b   Bartsch, Georg ^b   Miranda, Gus ^c   Skinner, Eila C ^d   Daneshmand, Siamak ^c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Case control studies; Pathology; Prognosis; Transitional cell carcinoma; Urinary bladder neoplasms

Indexed keywords

ADULT; AGED; ANTHROPOMETRIC PARAMETERS; ARTICLE; BLADDER CARCINOMA; CANCER ADJUVANT THERAPY; CANCER CELL; CANCER PROGNOSIS; CASE CONTROL STUDY; CELL DIFFERENTIATION; CONTROLLED STUDY; CYSTECTOMY; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; LYMPH NODE DISSECTION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OVERALL SURVIVAL; POTENTIAL DIFFERENCE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RECURRENCE FREE SURVIVAL; SQUAMOUS CELL; TRANSITIONAL CELL CARCINOMA;

CASE-CONTROL STUDIES; PATHOLOGY; PROGNOSIS; TRANSITIONAL CELL CARCINOMA; URINARY BLADDER NEOPLASMS;

AGED; CARCINOMA, SQUAMOUS CELL; CARCINOMA, TRANSITIONAL CELL; CASE-CONTROL STUDIES; COMBINED MODALITY THERAPY; CYSTECTOMY; FEMALE; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIER ESTIMATE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; NEOPLASMS, GLANDULAR AND EPITHELIAL; OUTCOME ASSESSMENT (HEALTH CARE); PROGNOSIS; PROPORTIONAL HAZARDS MODELS; URINARY BLADDER NEOPLASMS;

EID: 84892508513     PISSN: 10781439     EISSN: 18732496     Source Type: Journal    
DOI: 10.1016/j.urolonc.2012.08.017     Document Type: Article

References (28)

1. Cote RJ, Mitra AP, Amin MB. Bladder and urethra. In: Weidner N, Cote RJ, Suster S, Weiss LM, editors. Modern surgical pathology. 2nd ed. Philadelphia: Saunders; 2009. p. 1079-120.
2. Kantor A.F., Hartge P., Hoover R.N., Fraumeni J.F. Epidemiological characteristics of squamous cell carcinoma and adenocarcinoma of the bladder. Cancer Res 1988, 48:3853-3855.
3. Mazzucchelli L., Bacchi M., Studer U.E., Markwalder R., Sonntag R.W., Kraft R. Invasion depth is the most important prognostic factor for transitional-cell carcinoma in a prospective trial of radical cystectomy and adjuvant chemotherapy. Int J Cancer 1994, 57:15-20.
4. Yang M.H., Yen C.C., Chen P.M., et al. Prognostic-factors-based risk-stratification model for invasive urothelial carcinoma of the urinary bladder in Taiwan. Urology 2002, 59:232-238.
5. Grace D.A., Winter C.C. Mixed differentiation of primary carcinoma of the urinary bladder. Cancer 1968, 21:1239-1243.
6. Fegen J.P., Albert D.J., Persky L. Adenocarcinoma and transitional cell carcinoma occurring simultaneously in the urinary bladder (mixed tumor). J Surg Oncol 1971, 3:387-392.
7. Shapur N.K., Katz R., Pode D., et al. Is radical cystectomy mandatory in every patient with variant histology of bladder cancer. Rare Tumors 2011, 3:e22.
8. Erdemir F., Tunc M., Ozcan F., et al. The effect of squamous and/or glandular differentiation on recurrence, progression and survival in urothelial carcinoma of bladder. Int Urol Nephrol 2007, 39:803-807.
9. Honma I., Masumori N., Sato E., et al. Local recurrence after radical cystectomy for invasive bladder cancer: an analysis of predictive factors. Urology 2004, 64:744-748.
10. Antunes A.A., Nesrallah L.J., Dall'Oglio M.F., et al. The role of squamous differentiation in patients with transitional cell carcinoma of the bladder treated with radical cystectomy. Int Brazilian J Urol 2007, 33:339-345.
11. Frazier H.A., Robertson J.E., Dodge R.K., Paulson D.F. The value of pathologic factors in predicting cancer-specific survival among patients treated with radical cystectomy for transitional cell carcinoma of the bladder and prostate. Cancer 1993, 71:3993-4001.
12. Vecchioli Scaldazza C., Morosetti C. Squamous metaplasia as a prognostic factor in urothelial carcinoma of the bladder. Minerva Urol Nefrol 1992, 44:97-100.
13. Jozwicki W., Domaniewski J., Skok Z., Wolski Z., Domanowska E., Jozwicka G. Usefulness of histologic homogeneity estimation of muscle-invasive urinary bladder cancer in an individual prognosis: a mapping study. Urology 2005, 66:1122-1126.
14. Kastritis E., Dimopoulos M.A., Antoniou N., et al. The outcome of patients with advanced pure squamous or mixed squamous and transitional urothelial carcinomas following platinum-based chemotherapy. Anticancer Res 2006, 26:3865-3869.
15. Scosyrev E., Ely B.W., Messing E.M., et al. Do mixed histological features affect survival benefit from neoadjuvant platinum-based combination chemotherapy in patients with locally advanced bladder cancer? A secondary analysis of Southwest Oncology Group-Directed Intergroup Study (S8710). Brit J Urol Int 2011, 108:693-699.
16. Wasco M.J., Daignault S., Zhang Y., et al. Urothelial carcinoma with divergent histologic differentiation (mixed histologic features) predicts the presence of locally advanced bladder cancer when detected at transurethral resection. Urology 2007, 70:69-74.
17. Kim S.P., Frank I., Cheville J.C., et al. The impact of squamous and glandular differentiation on survival after radical cystectomy for urothelial carcinoma. J Urol 2012, 188:405-409.
18. Black PC, Kassouf W, Brown GA, et al. Variant histology in bladder cancer-experience in 1,246 patients undergoing cystectomy. In: Proceedings of the 102nd annual meeting of the American Urological Association; 2007 [abstr].
19. Chalasani V., Chin J.L., Izawa J.I. Histologic variants of urothelial bladder cancer and nonurothelial histology in bladder cancer. Can Urol Assoc J 2009, 3:S193-S198.
20. Black P.C., Brown G.A., Dinney C.P. The impact of variant histology on the outcome of bladder cancer treated with curative intent. Urol Oncol 2009, 27:3-7.
21. Stein J.P., Lieskovsky G., Cote R., et al. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001, 19:666-675.
22. Urinary bladder. In: Greene FL, Page DL, Fleming ID, et al., editors. AJCC cancer staging manual. 6th ed. New York: Springer-Verlag; 2002. p. 335-40.
23. Mostofi F.K., Sobin H.L., Torlini H. Histologic typing of urinary bladder tumors 1973, World Health Organization, Geneva.
24. Lopez-Beltran A, Sauter G, Gasser T, et al. Infiltrating urothelial carcinoma. In: Eble JN, Sauter G, Epstein JI, Sesterhenn IA, editors. World Health Organization classification of tumours. Pathology and genetics of tumours of the urinary system and male genital organs. Lyon: IARC Press; 2004. p. 93-109.
25. Billis A., Schenka A.A., Ramos C.C., Carneiro L.T., Araujo V. Squamous and/or glandular differentiation in urothelial carcinoma: prevalence and significance in transurethral resections of the bladder. Int Urol Nephrol 2001, 33:631-633.
26. Scosyrev E., Yao J., Messing E. Urothelial carcinoma versus squamous cell carcinoma of bladder: is survival different with stage adjustment?. Urology 2009, 73:822-827.
27. Rogers C.G., Palapattu G.S., Shariat S.F., et al. Clinical outcomes following radical cystectomy for primary nontransitional cell carcinoma of the bladder compared to transitional cell carcinoma of the bladder. J Urol 2006, 175:2048-2053.
28. Kalish L.A., Harrington D.P. Efficiency of balanced treatment allocation for survival analysis. Biometrics 1988, 44:815-821.