메뉴 건너뛰기




Volumn 60, Issue , 2014, Pages 235-245

The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts

Author keywords

GTP exchange factor; Osteoprotegerin, bone remodeling; Receptor activator of nuclear factor b ligand

Indexed keywords

ALKALINE PHOSPHATASE; CELL PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; KALIRIN PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOPROTEGERIN; RHO FACTOR; UNCLASSIFIED DRUG;

EID: 84892468097     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.12.023     Document Type: Article
Times cited : (25)

References (33)
  • 2
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: critical elements in the control of small G proteins
    • Bos J.L., Rehmann H., Wittinghofer A. GEFs and GAPs: critical elements in the control of small G proteins. Cell 2007, 129:865-877.
    • (2007) Cell , vol.129 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 5
    • 0037028489 scopus 로고    scopus 로고
    • Genomic organization and differential expression of Kalirin isoforms
    • McPherson C.E., Eipper B.A., Mains R.E. Genomic organization and differential expression of Kalirin isoforms. Gene 2002, 284:41-51.
    • (2002) Gene , vol.284 , pp. 41-51
    • McPherson, C.E.1    Eipper, B.A.2    Mains, R.E.3
  • 6
    • 3042701141 scopus 로고    scopus 로고
    • Kalirin expression is regulated by multiple promoters
    • McPherson C.E., Eipper B.A., Mains R.E. Kalirin expression is regulated by multiple promoters. J Mol Neurosci 2004, 22:51-62.
    • (2004) J Mol Neurosci , vol.22 , pp. 51-62
    • McPherson, C.E.1    Eipper, B.A.2    Mains, R.E.3
  • 7
    • 0035503505 scopus 로고    scopus 로고
    • Distinct roles for the two Rho GDP/GTP exchange factor domains of Kalirin in regulation of neurite growth and neuronal morphology
    • Penzes P., Johnson R.C., Kambampati V., Mains R.E., Eipper B.A. Distinct roles for the two Rho GDP/GTP exchange factor domains of Kalirin in regulation of neurite growth and neuronal morphology. J Neurosci 2001, 21:8426-8434.
    • (2001) J Neurosci , vol.21 , pp. 8426-8434
    • Penzes, P.1    Johnson, R.C.2    Kambampati, V.3    Mains, R.E.4    Eipper, B.A.5
  • 8
    • 0345305679 scopus 로고    scopus 로고
    • Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines
    • Ma X.M., Huang J., Wang Y., Eipper B.A., Mains R.E. Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines. J Neurosci 2003, 23:10593-10603.
    • (2003) J Neurosci , vol.23 , pp. 10593-10603
    • Ma, X.M.1    Huang, J.2    Wang, Y.3    Eipper, B.A.4    Mains, R.E.5
  • 9
    • 37048998562 scopus 로고    scopus 로고
    • Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturation
    • Ferraro F., Ma X.M., Sobota J.A., Eipper B.A., Mains R.E. Kalirin/Trio Rho guanine nucleotide exchange factors regulate a novel step in secretory granule maturation. Mol Biol Cell 2007, 18:4813-4825.
    • (2007) Mol Biol Cell , vol.18 , pp. 4813-4825
    • Ferraro, F.1    Ma, X.M.2    Sobota, J.A.3    Eipper, B.A.4    Mains, R.E.5
  • 10
    • 36049008808 scopus 로고    scopus 로고
    • Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines
    • Xie Z., Srivastava D.P., Photowala H., Kai L., Cahill M.E., Woolfrey K.M., et al. Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines. Neuron 2007, 56:640-656.
    • (2007) Neuron , vol.56 , pp. 640-656
    • Xie, Z.1    Srivastava, D.P.2    Photowala, H.3    Kai, L.4    Cahill, M.E.5    Woolfrey, K.M.6
  • 13
    • 84861211504 scopus 로고    scopus 로고
    • Megakaryocytes regulate expression of Pyk2 isoforms and caspase-mediated cleavage of actin in osteoblasts
    • Kacena M.A., Eleniste P.P., Cheng Y.H., Huang S., Shivanna M., Meijome T.E., et al. Megakaryocytes regulate expression of Pyk2 isoforms and caspase-mediated cleavage of actin in osteoblasts. J Biol Chem 2012, 287:17257-17268.
    • (2012) J Biol Chem , vol.287 , pp. 17257-17268
    • Kacena, M.A.1    Eleniste, P.P.2    Cheng, Y.H.3    Huang, S.4    Shivanna, M.5    Meijome, T.E.6
  • 14
    • 0025049142 scopus 로고
    • Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells
    • Udagawa N., Takahashi N., Akatsu T., Tanaka H., Sasaki T., Nishihara T., et al. Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. Proc Natl Acad Sci U S A 1990, 87:7260-7264.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 7260-7264
    • Udagawa, N.1    Takahashi, N.2    Akatsu, T.3    Tanaka, H.4    Sasaki, T.5    Nishihara, T.6
  • 15
    • 0033398996 scopus 로고    scopus 로고
    • Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors
    • Arai F., Miyamoto T., Ohneda O., Inada T., Sudo T., Brasel K., et al. Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors. J Exp Med 1999, 190:1741-1754.
    • (1999) J Exp Med , vol.190 , pp. 1741-1754
    • Arai, F.1    Miyamoto, T.2    Ohneda, O.3    Inada, T.4    Sudo, T.5    Brasel, K.6
  • 16
    • 0030685748 scopus 로고    scopus 로고
    • Effects of ethnicity and age or menopause on osteoblast function, bone mineralization, and osteoid accumulation in iliac bone
    • Parfitt A.M., Han Z.H., Palnitkar S., Rao D.S., Shih M.S., Nelson D. Effects of ethnicity and age or menopause on osteoblast function, bone mineralization, and osteoid accumulation in iliac bone. J Bone Miner Res 1997, 12:1864-1873.
    • (1997) J Bone Miner Res , vol.12 , pp. 1864-1873
    • Parfitt, A.M.1    Han, Z.H.2    Palnitkar, S.3    Rao, D.S.4    Shih, M.S.5    Nelson, D.6
  • 17
    • 84861091777 scopus 로고    scopus 로고
    • Kalirin, a key player in synapse formation, is implicated in human diseases
    • Mandela P., Ma X.M. Kalirin, a key player in synapse formation, is implicated in human diseases. Neural Plast 2012, 2012:728161.
    • (2012) Neural Plast , vol.2012 , pp. 728161
    • Mandela, P.1    Ma, X.M.2
  • 18
    • 59949098895 scopus 로고    scopus 로고
    • Role of serum P1NP measurement for monitoring treatment response in osteoporosis
    • Samoszuk M., Leuther M., Hoyle N. Role of serum P1NP measurement for monitoring treatment response in osteoporosis. Biomark Med 2008, 2:495-508.
    • (2008) Biomark Med , vol.2 , pp. 495-508
    • Samoszuk, M.1    Leuther, M.2    Hoyle, N.3
  • 19
    • 34548080918 scopus 로고    scopus 로고
    • Age-related changes in trabecular architecture differ in female and male C57BL/6J mice
    • Glatt V., Canalis E., Stadmeyer L., Bouxsein M.L. Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res 2007, 22:1197-1207.
    • (2007) J Bone Miner Res , vol.22 , pp. 1197-1207
    • Glatt, V.1    Canalis, E.2    Stadmeyer, L.3    Bouxsein, M.L.4
  • 22
  • 23
    • 38549181783 scopus 로고    scopus 로고
    • Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons
    • Ma X.M., Wang Y., Ferraro F., Mains R.E., Eipper B.A. Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons. J Neurosci 2008, 28:711-724.
    • (2008) J Neurosci , vol.28 , pp. 711-724
    • Ma, X.M.1    Wang, Y.2    Ferraro, F.3    Mains, R.E.4    Eipper, B.A.5
  • 24
    • 0038407651 scopus 로고    scopus 로고
    • Estrogen action and cytoplasmic signaling pathways. Part II: the role of growth factors and phosphorylation in estrogen signaling
    • Driggers P.H., Segars J.H. Estrogen action and cytoplasmic signaling pathways. Part II: the role of growth factors and phosphorylation in estrogen signaling. Trends Endocrinol Metab 2002, 13:422-427.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 422-427
    • Driggers, P.H.1    Segars, J.H.2
  • 25
    • 0036780306 scopus 로고    scopus 로고
    • Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes
    • Segars J.H., Driggers P.H. Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes. Trends Endocrinol Metab 2002, 13:349-354.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 349-354
    • Segars, J.H.1    Driggers, P.H.2
  • 26
    • 21244483493 scopus 로고    scopus 로고
    • Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells
    • Gilad L.A., Bresler T., Gnainsky J., Smirnoff P., Schwartz B. Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells. J Endocrinol 2005, 185:577-592.
    • (2005) J Endocrinol , vol.185 , pp. 577-592
    • Gilad, L.A.1    Bresler, T.2    Gnainsky, J.3    Smirnoff, P.4    Schwartz, B.5
  • 28
    • 70449526309 scopus 로고    scopus 로고
    • Passage-affected competitive regulation of osteoprotegerin synthesis and the receptor activator of nuclear factor-kappaB ligand mRNA expression in normal human osteoblasts stimulated by the application of cyclic tensile strain
    • Kusumi A., Kusumi T., Miura J., Tateishi T. Passage-affected competitive regulation of osteoprotegerin synthesis and the receptor activator of nuclear factor-kappaB ligand mRNA expression in normal human osteoblasts stimulated by the application of cyclic tensile strain. J Bone Miner Metab 2009, 27:653-662.
    • (2009) J Bone Miner Metab , vol.27 , pp. 653-662
    • Kusumi, A.1    Kusumi, T.2    Miura, J.3    Tateishi, T.4
  • 30
    • 84864339834 scopus 로고    scopus 로고
    • Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2
    • Tsubaki M., Satou T., Itoh T., Imano M., Yanae M., Kato C., et al. Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2. Mol Cell Endocrinol 2012, 361:219-231.
    • (2012) Mol Cell Endocrinol , vol.361 , pp. 219-231
    • Tsubaki, M.1    Satou, T.2    Itoh, T.3    Imano, M.4    Yanae, M.5    Kato, C.6
  • 31
    • 84863111789 scopus 로고    scopus 로고
    • Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading
    • Moriishi T., Fukuyama R., Ito M., Miyazaki T., Maeno T., Kawai Y., et al. Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading. PLoS One 2012, 7:e40143.
    • (2012) PLoS One , vol.7
    • Moriishi, T.1    Fukuyama, R.2    Ito, M.3    Miyazaki, T.4    Maeno, T.5    Kawai, Y.6
  • 32
    • 0036139964 scopus 로고    scopus 로고
    • Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-beta in bone remodeling in females but not in males
    • Sims N.A., Dupont S., Krust A., Clement-Lacroix P., Minet D., Resche-Rigon M., et al. Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-beta in bone remodeling in females but not in males. Bone 2002, 30:18-25.
    • (2002) Bone , vol.30 , pp. 18-25
    • Sims, N.A.1    Dupont, S.2    Krust, A.3    Clement-Lacroix, P.4    Minet, D.5    Resche-Rigon, M.6
  • 33
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
    • Wu X., Tu X., Joeng K.S., Hilton M.J., Williams D.A., Long F. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 2008, 133:340-353.
    • (2008) Cell , vol.133 , pp. 340-353
    • Wu, X.1    Tu, X.2    Joeng, K.S.3    Hilton, M.J.4    Williams, D.A.5    Long, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.