A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections

Journal of Antimicrobial Chemotherapy

Volumn 69, Issue 2, 2014, Pages 515-518

  Murray, Colin ^a   Shaw, Arlene ^a   Lloyd, Matthew ^a   Smith, Robin P ^a   Fardon, Thomas C ^a   Schembri, Stuart ^a   Chalmers, James D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Asthma; COPD; LRTIs; Pneumonia; Side effects

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; CLARITHROMYCIN;

ABDOMINAL DISCOMFORT; ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DIARRHEA; DISEASE EXACERBATION; DISEASE SEVERITY; FEMALE; GASTROINTESTINAL SYMPTOM; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; INJECTION SITE REACTION; INTENSIVE CARE; INTERVENTION STUDY; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY; NAUSEA; OUTCOME ASSESSMENT; RASH; THROMBOPHLEBITIS; THRUSH; TREATMENT DURATION; VERY ELDERLY; VOMITING;

ASTHMA; COPD; LRTIS; PNEUMONIA; SIDE EFFECTS;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; DRUG ADMINISTRATION SCHEDULE; EARLY MEDICAL INTERVENTION; FEMALE; HUMANS; MALE; MIDDLE AGED; PATIENT CARE TEAM; PROSPECTIVE STUDIES; RESPIRATORY TRACT INFECTIONS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84892457262     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt362     Document Type: Article

References (10)

1. Chalmers JD, Al-Khairalla M, Short PM et al. Proposed changes to management of lower respiratory tract infections in response to the Clostridium difficile epidemic. J Antimicrob Chemother 2010; 65: 608-18.
2. Aliberti S, Blasi F, Zanaboni AM et al. Duration of antibiotic therapy in hospitalised patients with community-acquired pneumonia. Eur Respir J 2010; 36: 128-34.
3. Lim WS, Baudouin SV, George RC et al. BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax 2009; 64 Suppl 3: iii1-55.
4. el Moussaoui R, de Borgie CA, van den Broek P et al. Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community acquired pneumonia: randomised, double blind study. BMJ 2006; 332: 1355.
5. Choudhury G, Mandal P, Singanayagam A et al. 7 day antibiotic courses have similar efficacy to prolonged courses in severe community acquired pneumonia-a propensity-adjusted analysis. Clin Microbiol Infect 2011;17: 1852-8.
6. HPA and Department of Health. Clostridium Difficile Infection:HowtoDeal With the Problem. December 2008. http://www.hpa.org.uk/webc/HPAwebFile/HPAweb_C/1232006607827 (10 August 2013, date last accessed).
7. Chalmers JD, Singanayagam A, Akram AR et al. Safety and efficacy of CURB65-guided antibiotic therapy in community-acquired pneumonia. J Antimicrob Chemother 2011; 66: 416-23.
8. Singanayagam A, Chalmers JD. Severity assessment scores to guide empirical use of antibiotics in community-acquired pneumonia. Lancet Respiratory Medicine 2013; doi:10.1016/S2213-2600(13)70084-5.
9. Anthonisen NR, Manfreda J, Warren CP et al. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann Intern Med 1987; 106: 196-204.
10. Schuetz P, Christ-Crain M, Thomann R et al. Effectof procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomised controlled trial. JAMA 2009; 302:1059-66.