The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China

BMC Gastroenterology

Volumn 14, Issue 1, 2014, Pages

  Zhang, Xiao mei ^a   Li, Jia xin ^b   Zhang, Gui ying ^a   Li, Xin hua ^a   Gu, Huan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Gastric cancer; Gastritis; Peptic ulcer; Serum pepsinogen; Stomach

Indexed keywords

PEPSINOGEN I; PEPSINOGEN II;

ADULT; ADVANCED CANCER; AGED; ARTICLE; ATROPHIC GASTRITIS; CHINA; CHINESE; CHRONIC GASTRITIS; CONTROLLED STUDY; DIAGNOSTIC VALUE; DUODENUM ULCER; EARLY CANCER; EARLY DIAGNOSIS; ELISA KIT; ENZYME BLOOD LEVEL; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PEPSINOGEN BLOOD LEVEL; RISK FACTOR; SENSITIVITY AND SPECIFICITY; STOMACH CANCER; STOMACH DISEASE; STOMACH ULCER; STUDENT T TEST;

ADULT; AGED; AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA; CASE-CONTROL STUDIES; CHINA; DUODENAL ULCER; FEMALE; GASTRITIS, ATROPHIC; HUMANS; MALE; MIDDLE AGED; PEPSINOGEN A; PEPSINOGEN C; PREDICTIVE VALUE OF TESTS; ROC CURVE; STOMACH NEOPLASMS; STOMACH ULCER; YOUNG ADULT;

EID: 84892449778     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-14-3     Document Type: Article

References (21)

1. Gritti I, Banfi G, Roi GS. Pepsinogens: physiology, pharmacology pathophysiology and exercise. Pharmacol Res 2000, 41:265-281. 10.1006/phrs.1999.0586, 10675278.
2. Kageyama T. Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development. Cell Mol Life Sci 2002, 59:288-306. 10.1007/s00018-002-8423-9, 11915945.
3. Lomba-Viana R, Dinis-Ribeiro M, Fonseca F, et al. Serum pepsinogen test for early detection of gastric cancer in a European country. Eur J Gastroenterol Hepatol 2012, 24:37-41. 10.1097/MEG.0b013e32834d0a0a, 21989121.
4. Ho June S, Se Jin J, Sung-Cheol Y, et al. Low levels of pepsinogen I and pepsinogen I/II ratio are valuable serologic markers for predicting extensive gastric corpus atrophy in patients undergoing endoscopic mucosectomy. Gut Liver 2010, 4:475-480. 10.5009/gnl.2010.4.4.475, 3021602, 21253295.
5. Leja M, Cine E, Rudzite D, et al. Prevalence of Helicobacter pylori infection and atrophic gastritis in Latvia. Eur J Gastroenterol Hepatol 2012, 24:1410-1417. 10.1097/MEG.0b013e3283583ca5, 23114744.
6. Venerito M, Kohrs S, Wex T, et al. Helicobacter pylori infection and fundic gastric atrophy are not associated with esophageal squamous cell carcinoma: a case-control study. Eur J Gastroenterol Hepatol 2011, 23:859-864. 10.1097/MEG.0b013e3283496469, 21811162.
7. Bornschein J, Selgrad M, Wex T, Kuester D, Malfertheiner P. Serological assessment of gastric mucosal atrophy in gastric cancer. BMC Gastroenterol 2012, 12:10. 10.1186/1471-230X-12-10, 3280182, 22289789.
8. Daugule I, Sudraba A, Chiu HM, et al. Gastric plasma biomarkers and Operative Link for Gastritis Assessment gastritis stage. Eur J Gastroenterol Hepatol 2011, 23:302-307. 10.1097/MEG.0b013e3283438ac3, 21389862.
9. Shin HR, Won YJ, Jung KW, et al. Nationwide cancer incidence in Korea, 1999 2001; first result using the national cancer incidence database. Cancer Res Treat 2005, 37:325-331. 10.4143/crt.2005.37.6.325, 2785938, 19956367.
10. Takahashi T, Saikawa Y, Kitagawa Y. Gastric cancer: current status of diagnosis and treatment. Cancers 2013, 5:48-63. 10.3390/cancers5010048, 3730304, 24216698.
11. Lan HC, Chen TS, Li AF, Chang FY, Lin HC. Additional corpus biopsy enhances the detection of Helicobacter pylori infection in a background of gastritis with atrophy. BMC Gastroenterol 2012, 12:182. 10.1186/1471-230X-12-182, 3573986, 23272897.
12. Choi IJ. Gastric cancer screening and diagnosis. Korean J Gastroenterol 2009, 54:67-76. 10.4166/kjg.2009.54.2.67, 19696534.
13. Liu CY, Wu CY, Lin JT, Lee YC, Yen AM, Chen TH. Multistate and multifactorial progression of gastric cancer: results from community-based mass screening for gastric cancer. J Med Screen 2006, 13(Suppl 1):S2-S5.
14. Kim HY, Kim N, Kang JM, Park YS, Lee DH, Kim YR, Kim JS, Jung HC, Song IS. Clinical meaning of pepsinogen test and Helicobacter pylori serology in the health check-up population in Korea. Eur J Gastroenterol Hepatol 2009, 21:606-612. 10.1097/MEG.0b013e3283086757, 19293719.
15. Watabe H, Mitsushima T, Yamaji Y, Okamoto M, Wada R, Kokubo T, Doi H, Yoshida H, Kawabe T, Omata M. Predicting the development of gastric cancer from combining helicobacter pylori antibodies and serum pepsinogen status: a prospective endoscopic cohort study. Gut 2005, 54:764-768. 10.1136/gut.2004.055400, 1774550, 15888780.
16. Sipponen P, Graham DY. Importance of atrophic gastritis in diagnostics and prevention of gastric cancer: application of plasma biomarkers. Scand J Gastroenterol 2007, 42:2-10. 10.1080/00365520600863720, 17190755.
17. Kang JM, Kim N, Yoo JY, Park YS, Lee DH, Kim HY, Lee HS, Choe G, Kim JS, Jung HC, Song IS. The role of serum pepsinogen and gastrin test for the detection of gastric cancer in Korea. Helicobacter 2008, 13:146-156. 10.1111/j.1523-5378.2008.00592.x, 18321304.
18. Miki K, Fujishiro M, Kodashima S, Yahagi N. Long-term results of gastric cancer screening using the serum pepsinogen test method among an asymptomatic middle-aged Japanese population. Dig Endosc 2009, 21:78-81. 10.1111/j.1443-1661.2009.00839.x, 19691778.
19. Tanaka Y, Mine K, Nakai Y, Mishima N, Nakagawa T. Serum pepsinogen I concentrations in peptic ulcer patients in relation to ulcer location and stage. Gut 1991, 32:849-852. 10.1136/gut.32.8.849, 1378950, 1885064.
20. Iijima K, Koike T, Abe Y, Ara N, Uno K, Imatani A, Ohara S, Shimosegawa T. Alteration of correlation between serum pepsinogen concentrations and gastric acid secretion after H. pylori eradication. J Gastroenterol 2009, 44(8):819-825. 10.1007/s00535-009-0066-2, 19440811.
21. Lorente S, Doiz O, Trinidad Serrano M, Castillo J, Lanas A. Helicobacter pylori stimulates pepsinogen secretion from isolated human peptic cells. Gut 2002, 50(1):13-18. 10.1136/gut.50.1.13, 1773080, 11772960.