Piloting and validation of a novel self-administered online cognitive screening tool in normal older persons: The Cognitive Function Test

International Journal of Geriatric Psychiatry

Volumn 29, Issue 2, 2014, Pages 198-206

  Trustram Eve, Catharine ^a   De Jager, Celeste A ^b,c  

^a Food for the Brain Foundation   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Alzheimer's disease; cognitive; computerized; memory; mild cognitive impairment; screening

Indexed keywords

ADULT; AGED; ALGORITHM; ALZHEIMER DISEASE; ARTICLE; COGNITIVE FUNCTION TEST; CONCURRENT VALIDITY; CORRELATION ANALYSIS; DISCRIMINANT VALIDITY; EPISODIC MEMORY; EXECUTIVE FUNCTION; FEMALE; FUNCTION TEST; HUMAN; INFORMATION PROCESSING; INTERNAL CONSISTENCY; MALE; MIDDLE AGED; MINI MENTAL STATE EXAMINATION; NORMAL HUMAN; ONLINE ANALYSIS; PILOT STUDY; RELIABILITY; SELF ADMINISTRATION TEST; VALIDATION STUDY; VELOCITY;

ALZHEIMER'S DISEASE; COGNITIVE; COMPUTERIZED; MEMORY; MILD COGNITIVE IMPAIRMENT; SCREENING;

AGED; COGNITION; COGNITION DISORDERS; DIAGNOSTIC SELF EVALUATION; EXECUTIVE FUNCTION; FEMALE; GERIATRIC ASSESSMENT; HUMANS; INTERNET; MALE; MASS SCREENING; MEMORY; MIDDLE AGED; PILOT PROJECTS; QUESTIONNAIRES; REPRODUCIBILITY OF RESULTS;

EID: 84892435255     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.3993     Document Type: Article

References (42)

1. Amieva H, Jacqmin-Gadda H, Orgogozo JM, et al,. May 2005. The 9 year cognitive decline before dementia of the Alzheimer type: a prospective population-based study. Brain 128 (Pt 5): 1093-1101. (Pubitemid 40675464)
2. Anderson EJ, de Jager CA, Iversen SD,. 2006. The Placing Test: preliminary investigations of a quick and simple memory test designed to be sensitive to pre-dementia Alzheimer's disease but not to normal ageing. J Clin Exp Neuropsychol 28: 843-858. doi: 10.1080/13803390591001016 (Pubitemid 44034728)
3. Baddeley A, Della Sala S, Papagno C, Spinnler H,. 1997. Dual-task performance in dysexecutive and nondysexecutive patients with a frontal lesion. Neuropsychology 11: 187-194. doi: 10.1037/0894-4105.11.2.187 (Pubitemid 27211807)
4. Barnes DE, Yaffe K,. 2011. The projected effect of risk factor reduction on Alzheimer's disease prevalence. Lancet Neurol 10 (9): 819-828. doi: 10.1016/S1474-4422(11)70072-2. Epub Jul 19. Review.
5. Blackwell AD, Sahakian BJ, Vesey R, et al,. 2004. Detecting dementia: novel neuropsychological markers of preclinical Alzheimer's disease. Dement Geriatr Cogn Disord 17: 42-48. doi: 10.1159/000074081 (Pubitemid 37499966)
6. Blessed G, Tomlinson BE, Roth M,. 1968. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 114: 797-811. doi: 10.1192/bjp.114.512.797
7. Chen P, Ratcliff G, Belle SH, et al,. 2000. Cognitive tests that best discriminate between presymptomatic AD and those who remain nondemented. Neurology 55: 1847-1853. doi: 10.1212/WNL.55.12.1847 (Pubitemid 32103967)
8. Crook T, Bahar H, Sudilovsky A,. 1987 -1988. Age-associated memory impairment: diagnostic criteria and treatment strategies. Int J Neurol 21-22: 73-82. Review.
9. Darby D, Maruff P, Collie A, McStephen M,. 2002. Mild cognitive impairment can be detected by multiple assessments in a single day. Neurology 59 (7): 1042-1046. doi: 10.1212/WNL.59.7.1042
10. de Jager CA, Budge MM,. 2005. Stability and predictability of the classification of mild cognitive impairment as assessed by episodic memory test performance over time. Neurocase 11: 72-79. (Pubitemid 40372863)
11. de Jager CA, Hogervorst E, Combrinck M, Budge MM,. 2003a. Sensitivity and specificity of neuropsychological tests for mild cognitive impairment, vascular cognitive impairment and Alzheimer's disease. Psychol Med 33 (6): 1039-1050. doi: 10.1017/S0033291703008031 (Pubitemid 37009822)
12. de Jager CA, Budge MM, Clarke R,. 2003b. Utility of TICS-M for the assessment of cognitive function in older adults. Int J Geriatr Psychiatry 18 (4): 318-324. doi: 10.1002/gps.830 (Pubitemid 36503043)
13. Dubois B, Feldman HH, Jacova C, et al,. 2007. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 6: 734-746. doi: 10.1016/S1474-4422(07)70178-3 (Pubitemid 47058377)
14. Dwolatzky T, Whitehead V, Doniger GM, et al,. 2003. Validity of a novel computerized cognitive battery for mild cognitive impairment. BMC Geriatr 3: 4. doi: 10.1186/1471-2318-3-4
15. Folstein MF, Folstein SE, McHugh PR,. 1975. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189-198.
16. Fowler KS, Saling MM, Conway EL, Semple JM, Louis WJ,. 1997. Computerized neuropsychological tests in the early detection of dementia: prospective findings. J Int Neuropsychol Soc 3 (2): 139-146. (Pubitemid 27168262)
17. Grober E, Kawas C,. 1997. Learning and retention in preclinical and early Alzheimer's disease. Psychol Aging 12 (1): 183-188. doi: 10.1037//0882-7974.12. 1.183 (Pubitemid 27157923)
18. Hänninen T, Hallikainen M, Koivisto K, et al,. 1995. A follow-up study of age-associated memory impairment neuropsychological predictors of dementia. J Am Geriatr Soc 43: 1007-1015
19. Jack CR Jr., Wiste HJ, Vemuri P, et al,. 2010. Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease. Brain 133: 3336-3348. doi: 10.1093/brain/awq277
20. Kawas CH, Corrada MM, Brookmeyer R, et al,. Apr 8 2003. Visual memory predicts Alzheimer's disease more than a decade before diagnosis. Neurology 60 (7): 1089-1093. PubMed PMID: 12682311 (Pubitemid 36418765)
21. Maruff P, Thomas E, Cysique L, et al,. 2009. Validity of the CogState brief battery: relationship to standardized tests and sensitivity to cognitive impairment in mild traumatic brain injury, schizophrenia, and AIDS dementia complex. Arch Clin Neuropsychol 24 (2): 165-178. doi: 10.1093/arclin/acp010
22. Morris JC,. 1997. Clinical dementia rating: a reliable and valid diagnostic and staging measure for dementia of the Alzheimer type. Int Psychogeriatr 9 (Suppl 1): 173-176; discussion 177-8. doi: 10.1017/ S1041610297004870 (Pubitemid 28045357)
23. Nagy Z, Jobst KA, Esiri MM, et al,. 1996. Hippocampal pathology reflects memory deficit and brain imaging measurements in Alzheimer's disease: clinicopathologic correlations using three sets of pathologic diagnostic criteria. Dementia 7 (2): 76-81. doi: 10.1159/000106857
24. Nasreddine ZS, Phillips NA, Bédirian V, et al,. 2005. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc 53: 695-699. doi: 10.1111/j.1532-5415.2005.53221.x (Pubitemid 41623495)
25. Oulhaj A, Wilcock GK, Smith AD, de Jager CA,. Nov 3 2009. Predicting the time of conversion to MCI in the elderly: role of verbal expression and learning. Neurology 73 (18): 1436-42. doi: 10.1212/WNL.0b013e3181c0665f. Epub 2009 Sep 30.
26. Petersen RC, Thomas RG, Grundman M, et al,. 2005. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med 352: 2379-2388. doi: 10.1056/NEJMoa050151
27. Petersen RC, Roberts RO, Knopman DS, et al,. Sep 7 2010. Prevalence of mild cognitive impairment is higher in men. The Mayo Clinic Study of Aging. Neurology 75 (10): 889-897. doi: 10.1212/WNL.0b013e3181f11d85.
28. Robbins TW, James M, Owen AM, et al,. 1994. Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers. Dementia 5 (5): 266-281. doi: 10.1159/000106735 (Pubitemid 24231105)
29. Roth M, Huppert FA, Tym E, Mountjoy CQ,. 1988. CAMDEX: The Cambridge Examination for Mental Disorders of the Elderly. Cambridge University Press: Cambridge.
30. Salthouse TA,. 1992. Influence of processing speed on adult age differences in working memory. Acta Psychol 79: 155-170. doi: 10.1016/0001-6918(92)90030-H
31. Simpson PM, Wesnes KA, Christmas LA,. 1989. A computerized system for the assessment of drug-induced performance changes in young elderly or demented populations. Br J Clin Pharmacol 27: 711-712.
32. Smith A, (ed.). 1995. Symbol Digits Modalities Test Manual. Western Psychological Services: Los Angeles.
33. Solomon PR, Hirschoff A, Kelly B, et al,. 1998. A 7 minute neurocognitive screening battery highly sensitive to Alzheimer's disease. Arch Neurol 55 (3): 349-355. doi: 10.1001/archneur.55.3.349 (Pubitemid 28146200)
34. Sperling R, Johnson K,. 2010. Pro: can biomarkers be gold standards in Alzheimer's disease? Alzheimers Res Ther 2: 17. doi: 10.1186/alzrt41
35. Tierney MC, Lermer MA,. 2010. Computerized cognitive assessment in primary care to identify patients with suspected cognitive impairment. J Alzheimers Dis 20 (3): 823-832. doi: 10.3233/JAD-2010-091672
36. Tierney MC, Szalai JP, Snow WG, Fisher RH,. 1996. Prediction of probable Alzheimer's disease in memory-impaired patients: a prospective longitudinal study. Neurology 46 (3): 661-665. doi: 10.1212/WNL.46.3.661 (Pubitemid 26099629)
37. Tondelli M, Wilcock GK, Nichelli P, et al,. 2011. Structural MRI changes detectable up to ten years before clinical Alzheimer's disease. Neurobiol Aging 33 (4): 825. doi: 10.1016/j.neurobiolaging.2011.05.018
38. Tornatore JB, Hill E, Laboff JA, McGann ME,. 2005. Self-administered screening for mild cognitive impairment: initial validation of a computerized test battery. J Neuropsychiatry Clin Neurosci 17 (1): 98-105. doi: 10.1176/appi.neuropsych.17.1.98 (Pubitemid 40283776)
39. Welsh KA, Butters N, Hughes JP, Mohs RC, Heyman A,. 1992. Detection and staging of dementia in Alzheimer's disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer's Disease. Arch Neurol 49: 448-452.
40. Wesnes KA,. 2006. Cognitive function testing: the case for standardization and automation. J Br Menopause Soc 12 (4): 158-163. doi: 10.1258/136218006779160544 (Pubitemid 46017603)
41. Wesnes KA, McKeith I, Edgar C, Emre M, Lane R,. 2005. Benefits of rivastigmine on attention in dementia associated with Parkinson disease. Neurology 65: 1654-1656. doi: 10.1212/01.wnl.0000184517.69816.e9 (Pubitemid 41689487)
42. Wild K, Howieson D, Webbe F, Seelye A, Kaye J,. 2008. Status of computerized cognitive testing in aging: a systematic review. Alzheimers Dement, 4 (6): 428-437. doi: 10.1159/000113719. (Pubitemid 351347867)