Pseudoephedrine/ephedrine shows potent anti-inflammatory activity against TNF-α-mediated acute liver failure induced by lipopolysaccharide/d- galactosamine

European Journal of Pharmacology

Volumn 724, Issue 1, 2014, Pages 112-121

  Wu, Zhongping ^a   Kong, Xiangliang ^a   Zhang, Tong ^a   Ye, Jin ^a   Fang, Zhaoqin ^a   Yang, Xuejun ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Acute liver failure; Anti inflammatory activity; Ephedrine; Hepatotoxicity; Kupffer cell; Pseudoephedrine

Indexed keywords

ALANINE AMINOTRANSFERASE; BILIRUBIN; EPHEDRINE; GALACTOSAMINE; I KAPPA B ALPHA; LIPOPOLYSACCHARIDE; MALONALDEHYDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PSEUDOEPHEDRINE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LIVER FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; BILE DUCT DISEASE; CELL ACTIVATION; CELL INFILTRATION; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DRUG EFFECT; HISTOPATHOLOGY; HYPERPLASIA; INFLAMMATORY CELL; INTRACELLULAR TRANSPORT; KUPFFER CELL; LIVER CELL; LIVER NECROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TRANSPORT; RAT; SYMPATHOMIMETIC EFFECT;

ACUTE LIVER FAILURE; ANTI-INFLAMMATORY ACTIVITY; EPHEDRINE; HEPATOTOXICITY; KUPFFER CELL; PSEUDOEPHEDRINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CHEMOKINE CCL2; EPHEDRINE; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LIVER; LIVER FAILURE, ACUTE; MALE; NF-KAPPA B; PSEUDOEPHEDRINE; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892380880     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.11.032     Document Type: Article

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