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Volumn 28, Issue 2, 2014, Pages 181-186

Incomplete adherence to antiretroviral therapy is associated with higher levels of residual HIV-1 viremia

Author keywords

HIV reservoir; Medication adherence; Residual viremia

Indexed keywords

ANTIRETROVIRUS AGENT; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PROTEINASE INHIBITOR;

EID: 84892374299     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0000000000000123     Document Type: Article
Times cited : (64)

References (34)
  • 1
    • 27544501320 scopus 로고    scopus 로고
    • Residual viraemia in subjects with chronic HIV infection and viral load 50copies/ml: The impact of highly active antiretroviral therapy
    • Palmisano L, Giuliano M, Nicastri E, Pirillo MF, Andreotti M, Galluzzo CM, et al. Residual viraemia in subjects with chronic HIV infection and viral load
    • (2005) AIDS , vol.19 , pp. 1843-1847
    • Palmisano, L.1    Giuliano, M.2    Nicastri, E.3    Pirillo, M.F.4    Andreotti, M.5    Galluzzo, C.M.6
  • 2
    • 41649083599 scopus 로고    scopus 로고
    • Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy
    • Palmer S, Maldarelli F, Wiegand A, Bernstein B, Hanna GJ, Brun SC, et al. Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy. Proc Natl Acad Sci USA 2008; 105:3879-3884.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3879-3884
    • Palmer, S.1    Maldarelli, F.2    Wiegand, A.3    Bernstein, B.4    Hanna, G.J.5    Brun, S.C.6
  • 3
    • 78549260677 scopus 로고    scopus 로고
    • Evidence of persistent low-level viremia in long-term HAART-suppressed HIV-infected individuals
    • Hatano H, Delwart EL, Norris PJ, Lee TH, Neilands TB, Kelley CF, et al. Evidence of persistent low-level viremia in long-term HAART-suppressed, HIV-infected individuals. AIDS 2010; 24:2535-2539.
    • (2010) AIDS , vol.24 , pp. 2535-2539
    • Hatano, H.1    Delwart, E.L.2    Norris, P.J.3    Lee, T.H.4    Neilands, T.B.5    Kelley, C.F.6
  • 4
    • 68349139711 scopus 로고    scopus 로고
    • HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
    • Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, et al. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med 2009; 15:893-900.
    • (2009) Nat Med , vol.15 , pp. 893-900
    • Chomont, N.1    El-Far, M.2    Ancuta, P.3    Trautmann, L.4    Procopio, F.A.5    Yassine-Diab, B.6
  • 5
    • 33746902816 scopus 로고    scopus 로고
    • Adherence to antiretroviral therapy in sub-Saharan Africa and North America: A meta-analysis
    • Mills EJ, Nachega JB, Buchan I, Orbinski J, Attaran A, Singh S, et al. Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis. JAMA 2006; 296:679-690.
    • (2006) JAMA , vol.296 , pp. 679-690
    • Mills, E.J.1    Nachega, J.B.2    Buchan, I.3    Orbinski, J.4    Attaran, A.5    Singh, S.6
  • 6
    • 34247583029 scopus 로고    scopus 로고
    • Adherence to nonnucleoside reverse transcriptase inhibitor-based HIV therapy and virologic outcomes
    • Nachega JB, Hislop M, Dowdy DW, Chaisson RE, Regensberg L, Maartens G. Adherence to nonnucleoside reverse transcriptase inhibitor-based HIV therapy and virologic outcomes. Ann Intern Med 2007; 146:564-573.
    • (2007) Ann Intern Med , vol.146 , pp. 564-573
    • Nachega, J.B.1    Hislop, M.2    Dowdy, D.W.3    Chaisson, R.E.4    Regensberg, L.5    Maartens, G.6
  • 7
    • 33748642352 scopus 로고    scopus 로고
    • Less than 95% adherence to nonnucleoside reverse-transcriptase inhibitor therapy can lead to viral suppression
    • Bangsberg DR. Less than 95% adherence to nonnucleoside reverse-transcriptase inhibitor therapy can lead to viral suppression. Clin Infect Dis 2006; 43:939-941.
    • (2006) Clin Infect Dis , vol.43 , pp. 939-941
    • Bangsberg, D.R.1
  • 8
    • 78650230394 scopus 로고    scopus 로고
    • Risk of viral failure declines with duration of suppression on highly active antiretroviral therapy irrespective of adherence level
    • Lima VD, Bangsberg DR, Harrigan PR, Deeks SG, Yip B, Hogg RS, Montaner JS. Risk of viral failure declines with duration of suppression on highly active antiretroviral therapy irrespective of adherence level. J Acquir Immune Defic Syndr 2010; 55:460-465.
    • (2010) J Acquir Immune Defic Syndr , vol.55 , pp. 460-465
    • Lima, V.D.1    Bangsberg, D.R.2    Harrigan, P.R.3    Deeks, S.G.4    Yip, B.5    Hogg, R.S.6    Montaner, J.S.7
  • 9
    • 4344636326 scopus 로고    scopus 로고
    • Prevalence of antiretroviral drug resistance in the HIV-1-infected urban indigent population in San Francisco: A representative study
    • Holodniy M, Charlebois ED, Bangsberg DR, Zolopa AR, Schulte M, Moss AR. Prevalence of antiretroviral drug resistance in the HIV-1-infected urban indigent population in San Francisco: a representative study. Int J STD AIDS 2004; 15:543-551.
    • (2004) Int J STD AIDS , vol.15 , pp. 543-551
    • Holodniy, M.1    Charlebois, E.D.2    Bangsberg, D.R.3    Zolopa, A.R.4    Schulte, M.5    Moss, A.R.6
  • 10
    • 12844260099 scopus 로고    scopus 로고
    • Adherence to highly active antiretroviral therapy in the homeless population in San Francisco: A prospective study
    • Moss AR, Hahn JA, Perry S, Charlebois ED, Guzman D, Clark RA, Bangsberg DR. Adherence to highly active antiretroviral therapy in the homeless population in San Francisco: a prospective study. Clin Infect Dis 2004; 39:1190-1198.
    • (2004) Clin Infect Dis , vol.39 , pp. 1190-1198
    • Moss, A.R.1    Hahn, J.A.2    Perry, S.3    Charlebois, E.D.4    Guzman, D.5    Clark, R.A.6    Bangsberg, D.R.7
  • 11
    • 33646034630 scopus 로고    scopus 로고
    • Adherence-resistance relationships for protease and nonnucleoside reverse transcriptase inhibitors explained by virological fitness
    • Bangsberg DR, Acosta EP, Gupta R, Guzman D, Riley ED, Harrigan PR, et al. Adherence-resistance relationships for protease and nonnucleoside reverse transcriptase inhibitors explained by virological fitness. AIDS 2006; 20:223-231.
    • (2006) AIDS , vol.20 , pp. 223-231
    • Bangsberg, D.R.1    Acosta, E.P.2    Gupta, R.3    Guzman, D.4    Riley, E.D.5    Harrigan, P.R.6
  • 12
    • 58149142981 scopus 로고    scopus 로고
    • Food insecurity is associated with incomplete HIV RNA suppression among homeless and marginally housed HIV-infected individuals in San Francisco
    • Weiser SD, Frongillo EA, Ragland K, Hogg RS, Riley ED, Bangsberg DR. Food insecurity is associated with incomplete HIV RNA suppression among homeless and marginally housed HIV-infected individuals in San Francisco. J Gen Intern Med 2009; 24:14-20.
    • (2009) J Gen Intern Med , vol.24 , pp. 14-20
    • Weiser, S.D.1    Frongillo, E.A.2    Ragland, K.3    Hogg, R.S.4    Riley, E.D.5    Bangsberg, D.R.6
  • 13
    • 0034027217 scopus 로고    scopus 로고
    • Adherence to protease inhibitors HIV-1 viral load, and development of drug resistance in an indigent population
    • Bangsberg DR, Hecht FM, Charlebois ED, Zolopa AR, Holodniy M, Sheiner L, et al. Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population. AIDS 2000; 14:357-366.
    • (2000) AIDS , vol.14 , pp. 357-366
    • Bangsberg, D.R.1    Hecht, F.M.2    Charlebois, E.D.3    Zolopa, A.R.4    Holodniy, M.5    Sheiner, L.6
  • 15
    • 10744228049 scopus 로고    scopus 로고
    • New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma
    • Palmer S, Wiegand AP, Maldarelli F, Bazmi H, Mican JM, Polis M, et al. New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol 2003; 41:4531-4536.
    • (2003) J Clin Microbiol , vol.41 , pp. 4531-4536
    • Palmer, S.1    Wiegand, A.P.2    Maldarelli, F.3    Bazmi, H.4    Mican, J.M.5    Polis, M.6
  • 16
    • 0034672295 scopus 로고    scopus 로고
    • Analysis and design issues for studies using censored biomarker measurements with an example of viral load measurements in HIV clinical trials
    • Hughes MD. Analysis and design issues for studies using censored biomarker measurements with an example of viral load measurements in HIV clinical trials. Stat Med 2000; 19:3171-3191.
    • (2000) Stat Med , vol.19 , pp. 3171-3191
    • Hughes, M.D.1
  • 17
    • 1842591991 scopus 로고    scopus 로고
    • Screening and behavioral counseling interventions in primary care to reduce alcohol misuse: Recommendation, statement
    • US Preventive Services Task Force
    • US Preventive Services Task Force. Screening and behavioral counseling interventions in primary care to reduce alcohol misuse: recommendation, statement. Ann Intern Med 2004; 140:554-556.
    • (2004) Ann Intern Med , vol.140 , pp. 554-556
  • 18
    • 79955402159 scopus 로고    scopus 로고
    • Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4R T cells
    • Anderson JA, Archin NM, Ince W, Parker D, Wiegand A, Coffin JM, et al. Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4R T cells. J Virol 2011; 85:5220-5223.
    • (2011) J Virol , vol.85 , pp. 5220-5223
    • Anderson, J.A.1    Archin, N.M.2    Ince, W.3    Parker, D.4    Wiegand, A.5    Coffin, J.M.6
  • 19
    • 0034946886 scopus 로고    scopus 로고
    • HIV-1 drug resistance profiles in children and adults with viral load of 50copies/ml receiving combination therapy
    • Hermankova M, Ray SC, Ruff C, Powell-Davis M, Ingersoll R, D'Aquila RT, et al. HIV-1 drug resistance profiles in children and adults with viral load of
    • (2001) JAMA , vol.286 , pp. 196-207
    • Hermankova, M.1    Ray, S.C.2    Ruff, C.3    Powell-Davis, M.4    Ingersoll, R.5    D'Aquila, R.T.6
  • 20
    • 33745245733 scopus 로고    scopus 로고
    • Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4R T cells
    • Bailey JR, Sedaghat AR, Kieffer T, Brennan T, Lee PK, Wind-Rotolo M, et al. Residual human immunodeficiency virus type 1 viremia in some patients on antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4R T cells. J Virol 2006; 80:6441-6457.
    • (2006) J Virol , vol.80 , pp. 6441-6457
    • Bailey, J.R.1    Sedaghat, A.R.2    Kieffer, T.3    Brennan, T.4    Lee, P.K.5    Wind-Rotolo, M.6
  • 21
    • 67249121143 scopus 로고    scopus 로고
    • Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
    • Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, et al. Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci USA 2009; 106: 9403-9408.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9403-9408
    • Dinoso, J.B.1    Kim, S.Y.2    Wiegand, A.M.3    Palmer, S.E.4    Gange, S.J.5    Cranmer, L.6
  • 22
    • 77749277080 scopus 로고    scopus 로고
    • Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy
    • McMahon D, Jones J, Wiegand A, Gange SJ, Kearney M, Palmer S, et al. Short-course raltegravir intensification does not reduce persistent low-level viremia in patients with HIV-1 suppression during receipt of combination antiretroviral therapy. Clin Infect Dis 2010; 50:912-919.
    • (2010) Clin Infect Dis , vol.50 , pp. 912-919
    • McMahon, D.1    Jones, J.2    Wiegand, A.3    Gange, S.J.4    Kearney, M.5    Palmer, S.6
  • 23
    • 77956856393 scopus 로고    scopus 로고
    • The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: A randomized controlled trial
    • Gandhi RT, Zheng L, Bosch RJ, Chan ES, Margolis DM, Read S, et al. The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial. PLoS Med 2010; 7:e1000321.
    • (2010) PLoS Med , vol.7
    • Gandhi, R.T.1    Zheng, L.2    Bosch, R.J.3    Chan, E.S.4    Margolis, D.M.5    Read, S.6
  • 24
    • 84860345691 scopus 로고    scopus 로고
    • Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: A randomized 48-week study
    • Llibre JM, Buzon MJ, Massanella M, Esteve A, Dahl V, Puertas MC, et al. Treatment intensification with raltegravir in subjects with sustained HIV-1 viraemia suppression: a randomized 48-week study. Antivir Ther 2012; 17:355-364.
    • (2012) Antivir Ther , vol.17 , pp. 355-364
    • Llibre, J.M.1    Buzon, M.J.2    Massanella, M.3    Esteve, A.4    Dahl, V.5    Puertas, M.C.6
  • 25
    • 79953000877 scopus 로고    scopus 로고
    • A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4R T cell response
    • Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, et al. A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4R T cell response. J Infect Dis 2011; 203:960-968.
    • (2011) J Infect Dis , vol.203 , pp. 960-968
    • Hatano, H.1    Hayes, T.L.2    Dahl, V.3    Sinclair, E.4    Lee, T.H.5    Hoh, R.6
  • 26
    • 0033609373 scopus 로고    scopus 로고
    • Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy
    • Zhang L, Ramratnam B, Tenner-Racz K, He Y, Vesanen M, Lewin S, et al. Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy. N Engl J Med 1999; 340:1605-1613.
    • (1999) N Engl J Med , vol.340 , pp. 1605-1613
    • Zhang, L.1    Ramratnam, B.2    Tenner-Racz, K.3    He, Y.4    Vesanen, M.5    Lewin, S.6
  • 27
    • 70349296826 scopus 로고    scopus 로고
    • Identification of ongoing human immunodeficiency virus type 1 (HIV-1) replication in residual viremia during recombinant HIV-1 poxvirus immunizations in patients with clinically undetectable viral loads on durable suppressive highly active antiretroviral therapy
    • Shiu C, Cunningham CK, Greenough T, Muresan P, Sanchez-Merino V, Carey V, et al. Identification of ongoing human immunodeficiency virus type 1 (HIV-1) replication in residual viremia during recombinant HIV-1 poxvirus immunizations in patients with clinically undetectable viral loads on durable suppressive highly active antiretroviral therapy. J Virol 2009; 83:9731-9742.
    • (2009) J Virol , vol.83 , pp. 9731-9742
    • Shiu, C.1    Cunningham, C.K.2    Greenough, T.3    Muresan, P.4    Sanchez-Merino, V.5    Carey, V.6
  • 28
    • 0141676556 scopus 로고    scopus 로고
    • Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years
    • Havlir DV, Strain MC, Clerici M, Ignacio C, Trabattoni D, Ferrante P, Wong JK. Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years. J Virol 2003; 77:11212-11219.
    • (2003) J Virol , vol.77 , pp. 11212-11219
    • Havlir, D.V.1    Strain, M.C.2    Clerici, M.3    Ignacio, C.4    Trabattoni, D.5    Ferrante, P.6    Wong, J.K.7
  • 29
    • 9144265028 scopus 로고    scopus 로고
    • Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication
    • Ramratnam B, Ribeiro R, He T, Chung C, Simon V, Vanderhoeven J, et al. Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication. J Acquir Immune Defic Syndr 2004; 35:33-37.
    • (2004) J Acquir Immune Defic Syndr , vol.35 , pp. 33-37
    • Ramratnam, B.1    Ribeiro, R.2    He, T.3    Chung, C.4    Simon, V.5    Vanderhoeven, J.6
  • 30
    • 78549245806 scopus 로고    scopus 로고
    • Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy
    • Yukl SA, Shergill AK, McQuaid K, Gianella S, Lampiris H, Hare CB, et al. Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy. AIDS 2010; 24:2451-2460.
    • (2010) AIDS , vol.24 , pp. 2451-2460
    • Yukl, S.A.1    Shergill, A.K.2    McQuaid, K.3    Gianella, S.4    Lampiris, H.5    Hare, C.B.6
  • 31
    • 77950537810 scopus 로고    scopus 로고
    • HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
    • Buzon MJ, Massanella M, Llibre JM, Esteve A, Dahl V, Puertas MC, et al. HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects. Nat Med 2010; 16:460-465.
    • (2010) Nat Med , vol.16 , pp. 460-465
    • Buzon, M.J.1    Massanella, M.2    Llibre, J.M.3    Esteve, A.4    Dahl, V.5    Puertas, M.C.6
  • 32
    • 84864283538 scopus 로고    scopus 로고
    • Ultrasensitive assessment of residual lowlevel HIV viremia in HAART-treated patients and risk of virological failure
    • Maggiolo F, Callegaro A, Cologni G, Bernardini C, Velenti D, Gregis G, et al. Ultrasensitive assessment of residual lowlevel HIV viremia in HAART-treated patients and risk of virological failure. J Acquir Immune Defic Syndr 2012; 60:473-482.
    • (2012) J Acquir Immune Defic Syndr , vol.60 , pp. 473-482
    • Maggiolo, F.1    Callegaro, A.2    Cologni, G.3    Bernardini, C.4    Velenti, D.5    Gregis, G.6
  • 33
    • 84869224844 scopus 로고    scopus 로고
    • Increased risk of virologic rebound in patients on antiviral therapy with a detectable HIV load 48copies/mL
    • Henrich TJ, Wood BR, Kuritzkes DR. Increased risk of virologic rebound in patients on antiviral therapy with a detectable HIV load
    • (2012) PLoS One , vol.7
    • Henrich, T.J.1    Wood, B.R.2    Kuritzkes, D.R.3
  • 34
    • 84867534933 scopus 로고    scopus 로고
    • Modest nonadherence to antiretroviral therapy promotes residual HIV-1 replication in the absence of virological rebound in plasma
    • Pasternak AO, de Bruin M, Jurriaans S, Bakker M, Berkhout B, Prins JM, Lukashov VV. Modest nonadherence to antiretroviral therapy promotes residual HIV-1 replication in the absence of virological rebound in plasma. J Infect Dis 2012; 206:1443-1452.
    • (2012) J Infect Dis , vol.206 , pp. 1443-1452
    • Pasternak, A.O.1    De Bruin, M.2    Jurriaans, S.3    Bakker, M.4    Berkhout, B.5    Prins, J.M.6    Lukashov, V.V.7


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