A human strain of Oxalobacter (HC-1) promotes enteric oxalate secretion in the small intestine of mice and reduces urinary oxalate excretion

Urological Research

Volumn 41, Issue 5, 2013, Pages 379-384

  Hatch, Marguerite ^a   Freel, Robert W ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Caecum; Distal colon; Ileum; Jejunum; Urinary oxalate

Indexed keywords

OXALIC ACID; PROBIOTIC AGENT;

ANIMAL TISSUE; ARTICLE; ASCENDING COLON; BACTERIAL COLONIZATION; BACTERIAL STRAIN; CECUM; CREATININE URINE LEVEL; DESCENDING COLON; FEMALE; HOMEOSTASIS; HUMAN; HYPEROXALURIA; ILEUM; INTESTINAL SECRETION; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; JEJUNUM; MALE; MOUSE; NONHUMAN; OXALOBACTER; OXALOBACTER HC 1; PRIORITY JOURNAL; SMALL INTESTINE; URINARY EXCRETION; ANIMAL EXPERIMENT; CONTROLLED STUDY; LARGE INTESTINE; OXALIC ACID URINE LEVEL; RAT STRAIN; URINE LEVEL; WILD TYPE;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; FEMALE; HUMANS; HYPEROXALURIA; INTESTINE, SMALL; MALE; MICE; MICE, INBRED C57BL; OXALATES; OXALOBACTER FORMIGENES; PROBIOTICS; RATS;

EID: 84892372064     PISSN: 03005623     EISSN: 14340879     Source Type: Journal    
DOI: 10.1007/s00240-013-0601-8     Document Type: Article

References (9)

1. Hatch M, Cornelius J, Allison M, Sidhu H, Peck A, Freel RW (2006) Oxalobacter sp. reduces urinary oxalate excretion by promoting enteric oxalate secretion. Kidney Int 69:691-698
2. Hatch M, Gjymishka A, Salido EC, Allison MJ, Freel RW (2010) Enteric oxalate elimination is induced and oxalate is normalized in a mouse model of primary hyperoxaluria following intestinal colonization with Oxalobacter. Am J Physiol Gastrointest Liver Physiol 300:G461-G469
3. Allison MJ, Dawson KA, Mayberry WR, Foss JG (1985) Oxalobacter formigenes gen. nov., sp. nov.: Oxalate-degrading anaerobes that inhabit the gastrointestinal tract. Arch Microbiol 141:1-7
4. Green ML, Hatch M, Freel RW (2005) Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. Am J Physiol Renal Physiol 289:F536-F543
5. Freel RW, Hatch M, Green M, Soleimani M (2006) Ileal oxalate absorption and urinary oxalate excretion are enhanced in Slc26a6 null mice. Am J Physiol Gastrointest Liver Physiol 290:G719-G728
6. Kharlamb V, Schelker J, Francois F, Jiang J, Holmes RP, Goldfarb DS (2011) Oral antibiotic treatment of Helicobacter pylori leads to persistently reduced intestinal colonization rates with Oxalobacter formigenes. J Endourol 25:1781-1785
7. Mittal RD, Kumar R, Bid HK, Mittal B (2005) Effect of antibiotics on Oxalobacter formigenes colonization of human gastrointestinal tract. J Endourol 19:102-106
8. Lange JN, Wood KD, Wong H, Otto R, Mufarrij PW, Knight J, Akpinar H, Holmes RP, Assimos DG (2012) Sensitivity of human strains of Oxalobacter formigenes to commonly prescribed antibiotics. Urology 79:1286-1289
9. Hoppe B, Beck B, Gatter N, von Unruh G, Tischer A, Hesse A, Laube N, Kaul P, Sidhu H (2006) Oxalobacter formigenes: A potential tool for the treatment of primary hyperoxaluria type 1. Kidney Int 70:1305-1311