Alzheimer's disease, sleep apnea, and positive pressure therapy

Current Treatment Options in Neurology

Volumn 15, Issue 6, 2013, Pages 669-676

  Bliwise, Donald L ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Clinical trials; Impaired cognition; Positive pressure therapy; Sleep apnea

Indexed keywords

APOLIPOPROTEIN E4;

ALZHEIMER DISEASE; CARDIOVASCULAR DISEASE; CAREGIVER; COGNITION; COMORBIDITY; DEMENTIA; DIABETES MELLITUS; DISEASE ASSOCIATION; FAMILY; GENOTYPE; HUMAN; HYPERSOMNIA; LETHARGY; MILD COGNITIVE IMPAIRMENT; MULTIINFARCT DEMENTIA; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK FACTOR; SLEEP DISORDERED BREATHING; THERAPY EFFECT;

EID: 84892368696     PISSN: 10928480     EISSN: 15343138     Source Type: Journal    
DOI: 10.1007/s11940-013-0262-5     Document Type: Review

References (70)

1. Yesavage JA, Bliwise D, Guilleminault C, et al. Preliminary communication: intellectual deficit and sleep-related respiratory disturbance in the elderly. Sleep. 1985;8:30-3.
2. Bliwise DL. Dementia. In: Kryger MH, Roth T, Dement WC, editors. Principles and practice of sleep medicine. 3rd ed. Philadelphia: Saunders; 2000. p. 1058-71.
3. Bliwise DL. Sleep in independently living and institutionalized elderly. In: Kryger MH, Roth T, Dement WC, editors. Principles and practice of sleep medicine. 5th ed. Philadelphia: Elsevier/Saunders; 2011. p. 1551-61.
4. Bliwise DL. Is sleep apnea a cause of reversible dementia in old age (editorial)? J Am Geriatr Soc. 1996;44:1407-9.
5. Ancoli-Israel S, Kripke DF, Klauber MR, et al. Sleep-disordered breathing in community-dwelling elderly. Sleep. 1991;14:486-95.
6. Ancoli-Israel S. Epidemiology of sleep disorders. Clin Geriatr Med. 1989;5:347-62.
7. Ancoli-Israel S, Klauber MR, Butters N, et al. Dementia in institutionalized elderly: relation to sleep apnea. J Am Geriatr Soc. 1991;39:258-63.
8. Ancoli-Israel S, Klauber MR, Kripke DF, et al. Sleep apnea in female patients in a nursing home: increased risk of mortality. Chest. 1989;96:1054-8.
9. Martin JL, Mory AK, Alessi CA. Nighttime oxygen desaturation and symptoms of sleep-disordered breathing in long-stay nursing home residents. J Gerontol Med Sci. 2005;60A:104-8.
10. Frohnhofen H, Roffe C. Intermittent nocturnal hypoxemia in individuals with dementia: prevalence and relationship with functional status. J Am Geriatr Soc. 2012;60:1997-9.
11. Onen SH, Dubray C, Decullier E, et al. Observation-based nocturnal sleep inventory: screening tool for sleep apnea in elderly people. J Am Geriatr Soc. 2008;56:1920-5.
12. Antonelli Incalzi R, Marra C, Salvigni BL, et al. Does cognitive dysfunction conform to a distinctive pattern in obstructive sleep apnea? J Sleep Res. 2004;13:79-86.
13. Roman GC. Vascular dementia prevention: a risk factor analysis. Cerebrovasc Dis. 2005;20 Suppl 2:91-100.
14. Cerhan JR, Folsom AR, Mortimer JA, et al. The ARIC Study Investigators. Correlates of cognitive function in middle-aged adults. Gerontology. 1998;44:95-105.
15. Elias MF, Wolf PA, d'Agostino RB. Untreated blood pressure level is inversely related to cognitive functioning: the Framingham Study. Am J Epidemiol. 1993;138:353-64.
16. Kilander L, Nyman H, Boberg M, et al. Hypertension is related to cognitive impairment: a 20-year follow-up of 999 men. Hypertension. 1998;31:780-6.
17. Farmer ME, White LR, Abbott RD, et al. Blood pressure and cognitive performance: the Framingham study. Am J Epidemiol. 1987;126:1103-14.
18. Launer LJ, Masaki K, Petrovitch H, et al. The association between midlife blood pressure levels and late-life cognitive function. JAMA. 1995;274:1846-51.
19. Bliwise DL, Yesavage JA, Tinklenberg J, et al. Sleep apnea in Alzheimer's Disease. Neurobiol Aging. 1989;10(4):343-6.
20. Yamout K, Goldstein FC, Lah JJ, et al. Neurocognitive correlates of nocturnal oxygen desaturation in a memory clinic population. J Clin Exp Neuropsych. 2012;34:325-32.
21. Bliwise DL, Nekich JC, Dement WC. Relative validity of self-reported snoring as a symptom of sleep apnea. Chest. 1991;99:600-8.
22. Sforza E, Roche F, Thomas-Anterion C, et al. Cognitive function and sleep related breathing disorders in a healthy elderly population: the Synapse Study. Sleep. 2010;33:515-21.
23. Tworoger SS, Lee S, Schernhammer ES, et al. The association of self-reported sleep duration, difficulty sleeping, and snoring with cognitive function in older women. Alzheimer Dis Assoc Disord. 2006;20:41-8.
24. Quan SF, Chan CS, Dement WC, et al. The association between obstructive sleep apnea and neurocognitive performance - the Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep. 2011;34:303-14B.
25. Boland LL, Shahar E, Iber C, et al. Measures of cognitive function in persons with varying degrees of sleep-disordered breathing: the Sleep Heart Health Study. J Sleep Res. 2002;11:265-72.
26. Ding J, Nieto FJ, Beauchamp Jr NJ, et al. Sleep-disordered breathing and white matter disease in the brainstem in older adults. Sleep. 2004;27:474-9.
27. Robbins J, Redline S, Ervin A, et al. Associations of sleep-disordered breathing and cerebral changes on MRI. J Clin Sleep Med. 2005;1:159-65.
28. Rothman KJ. Modern epidemiology. Boston: Little, Brown and Company; 1986.
29. Kushida CA, Nichols DA, Holmes TH, et al. Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: the Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep. 2012;35:1593-602.
30. Weaver TE, Mancini C, Maislin G, et al. Continuous positive airway pressure treatment of sleepy patients with milder obstructive sleep apnea: results of the CPAP Apnea Trial North American Program (CATNAP) randomized clinical trial. Am J Respir Crit Care Med. 2012;186:677-83.
31. Bliwise DL, Greenaway MC Will APPLES hit a ceiling? Comment on Quan, et al. The association between obstructive sleep apnea and neurocognitive performance - the Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep. 2011;34:249-50.
32. Bliwise DL. Sleep apnea, APO-E4, and Alzheimer's disease: 20 years and counting? J Psychosom Res. 2002;53:539-46.
33. Ancoli-Israel S, Palmer BW, Cooke JR, et al. Cognitive effects of treating obstructive sleep apnea in Alzheimer's Disease. J Am Geriatr Soc. 2008;56:2076-81.
34. Ayalon L, Ancoli-Israel S, Stepnowsky C, et al. Adherence to continuous positive airway pressure treatment in patients with Alzheimer's Disease and obstructive sleep apnea. Am J Geriatr Psychiatry. 2006;14:176-80.
35. Chong MS, Ayalon L, Marler M, et al. Continuous positive airway pressure reduces subjective daytime sleepiness in patients with mild to moderate Alzheimer's disease with sleep disordered breathing. J Am Geriatr Soc. 2006;54:777-81.
36. Cooke JR, Ancoli-Israel S, Liu L, et al. Continuous positive airway pressure deepens sleep in patients with Alzheimer's disease and obstructive sleep apnea. Sleep Med. 2009;10:1101-6.
37. Cooke JR, Ayalon L, Palmer BW, et al. Sustained use of CPAP slows deterioration of cognition, sleep and mood in patients with Alzheimer's disease and obstructive sleep apnea: a preliminary study. J Clin Sleep Med. 2009;5:305-9.
38. Nikodemova M, Finn L, Mignot E, et al. Association of sleep disordered breathing and cognitive deficit in APOE e4 carriers. Sleep. 2013; 36:873-80.
39. Caselli RJ, Reiman EM, Hentz JG, et al. A distinctive interaction between memory and chronic daytime somnolence in asymptomatic APOE e4 homozygotes. Sleep. 2002;25:447-53.
40. Cosentino II F, Bosco P, Drago V, et al. The APOE e4 allele increases the risk of impaired spatial working memory in obstructive sleep apnea. Sleep Med. 2008;9:831-9.
41. Gottlieb DJ, DeStefano AL, Foley DJ, et al. APOE epsilon4 is associated with obstructive sleep apnea/hypopnea: the Sleep Heart Health Study. Neurology. 2004;63:664-8.
42. O'Hara R, Schroder CM, Kraemer HC, et al. Nocturnal sleep apnea/hypopnea is associated with lower memory performance in APOE e4 carriers. Neurology. 2005;65:642-4.
43. Moraes W, Poyares D, Sukys-Claudino L, et al. Donepezil improves obstructive sleep apnea in Alzheimer's disease: a double-blind, placebo-controlled study. Chest. 2008;133:677-83.
44. Sukys-Claudino L, Moraes W, Guilleminault C, et al. Beneficial effect of donepezil on obstructive sleep apnea: a double-blind, placebo-controlled clinical trial. Sleep Med. 2012;13:290-6.
45. Heaton RK, Grant I, McSweeny AJ, et al. Psychological effects of continuous and nocturnal oxygen therapy in hypoxemic chronic obstructive pulmonary disease. Arch Intern Med. 1983;143:1941-7.
46. Gozal D, Row BW, Kheirandish L, et al. Increased susceptibility to intermittent hypoxia in aging rats: changes in proteasomal activity, neuronal apoptosis and spatial function. J Neurochem. 2003;86:1545-52.
47. Dayyat EA, Zhang SX, Wang Y, et al. Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea. BMC Neuroscience. 2012;13:77.
48. Decker MJ, Hue GE, Caudle WM, et al. Episodic neonatal hypoxia evokes executive dysfunction and regionally specific alterations in markers of dopamine signaling. Neuroscience. 2003;117:417-25.
49. Aloia MS, Arnedt JT, Davis JD, et al. Neuropsychological sequelae of obstructive sleep apnea-hypopnea syndrome: a critical review. J Int Neuropsychol Soc. 2004;10:772-85.
50. Bucks RS, Olaithe M, Eastwood P. Neurocognitive function in obstructive sleep apnoea: a meta-review. Respirology. 2013;18:61-70.
51. Lau EY, Eskes GA, Morrison DL, et al. Executive function in patients with obstructive sleep apnea treated with continuous positive airway pressure. J Int Neuropsychol Soc. 2010;16:1077-88.
52. Ju G, Yoon I-Y, Lee SD, et al. Effects of sleep apnea syndrome on delayed memory and executive function in elderly adults. J Am Geriatr Soc. 2012;60:1099-103.
53. Spira AP, Blackwell T, Stone KL, et al. Sleep-disordered breathing and cognition in older women. J Am Geriatr Soc. 2008;56:45-50.
54. Blackwell T, Yaffe K, Ancoli-Israel S, et al. Associations between sleep architecture and sleep-disordered breathing and cognition in older community-dwelling men: the Osteoporotic Fractures in Men Sleep Study. J Am Geriatr Soc. 2011;59:2217-25.
55. Foley D, Monjan A, Masaki K, et al. Daytime sleepiness is associated with 3-year incident dementia and cognitive decline in older Japanese-American men. J Am Geriatr Soc. 2001;49:1628-32.
56. Yaffe K, Laffan AM, Harrison SL, et al. Sleep-disordered breathing, hypoxia, and risk for mild cognitive impairment and dementia in older women. JAMA. 2011;306:613-9.
57. Tractenberg RE, Singer CM, Kaye JA. Symptoms of sleep disturbance in persons with Alzheimer's disease and normal elderly. J Sleep Res. 2005;14:177-85.
58. Tractenberg RE, Singer CM, Kaye JA. Characterizing sleep problems in persons with Alzheimer's disease and normal elderly. J Sleep Res. 2006;15:97-103.
59. Zimmerman ME, Aloia MS. A review of neuroimaging in obstructive sleep apnea. J Clin Sleep Med. 2006;2:461-71.
60. Kumar R, Birrer BVX, Macey PM, et al. Reduced mammillary body volume in patients with obstructive sleep apnea. Neurosci Letters. 2008;438:330-4.
61. Macey PM, Kumar R, Woo MA, et al. Brain structural changes in obstructive sleep apnea. Sleep. 2008;31:967-77.
62. Kim H, Yun CH, Thomas RL, et al. Obstructive sleep apnea as a risk factor for cerebral white matter change in a middle-aged and older general population. Sleep. 2013;36:709-15B.
63. Joo EY, Jeon S, Kim ST, et al. Localized cortical thinning in patients with obstructive sleep apnea syndrome. Sleep. 2013;36:1153-62.
64. Canessa N, Castronovo V, Cappa SF, et al. Obstructive sleep apnea: brain structural changes and neurocognitive function before and after treatment. Am J Respir Crit Care Med. 2011;183:1419-26.
65. Zhang X, Ma L, Li S, et al. A functional MRI evaluation of frontal dysfunction in patients with severe sleep apnea. Sleep Med. 2011;12:335-40.
66. Thomas RJ, Rosen BR, Stern CE, et al. Functional imaging of working memory in obstructive sleep-disordered breathing. J Appl Physiol. 2005;98:2226-34.
67. Ayalon L, Ancoli-Israel S, Klemfuss Z, et al. Increased brain activation during verbal learning in obstructive sleep apnea. Neuroimage. 2006;31:1817-25.
68. Archbold KH, Borghesani PR, Mahurin RK, et al. Neural activation patterns during working memory tasks and OSA disease severity. J Clin Sleep Med. 2009;5:21-7.
69. Lee SD, Ju G, Kim J-W, et al. Improvement of EEG slowing in OSAS after CPAP treatment. J Psychosom Res. 2012;73:126-31.
70. Sharafkhaneh A, Giray N, Richardson P, et al. Association of psychiatric disorders and sleep apnea in a large cohort. Sleep. 2005;28:1405-11.