Development and validation of an LCMS method to determine the pharmacokinetic profiles of caffeic acid phenethyl amide and caffeic acid phenethyl ester in male Sprague-Dawley rats

Biomedical Chromatography

Volumn 28, Issue 2, 2014, Pages 241-246

  Yang, John ^a   Bowman, Phillip D ^b   Kerwin, Sean M ^a   Stavchansky, Salomon ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

Caffeic acid phenethyl amide; Caffeic acid phenethyl ester; LCMS; Pharmacokinetics; Sprague Dawley rats

Indexed keywords

AMIDES; ELECTROSPRAY IONIZATION; ESTERS; MASS SPECTROMETRY; RATS;

CAFFEIC ACID PHENETHYL AMIDE; CAFFEIC ACID PHENETHYL ESTER; CAFFEIC ACIDS; HALF LIVES; LCMS; PHARMACOKINETIC PROFILES; QUANTITATIVE DETERMINATIONS; RAT PLASMA; REVERSE PHASIS; SPRAGUE-DAWLEY RATS;

PHARMACOKINETICS;

AMIDE; CAFFEIC ACID PHENETHYL AMIDE; CAFFEIC ACID PHENETHYL ESTER; UNCLASSIFIED DRUG;

ARTICLE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG ELIMINATION; DRUG HALF LIFE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; RAT; VALIDATION PROCESS;

RATTUS;

CAFFEIC ACID PHENETHYL AMIDE; CAFFEIC ACID PHENETHYL ESTER; LCMS; PHARMACOKINETICS; SPRAGUE-DAWLEY RATS;

ANIMALS; CAFFEIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; LIMIT OF DETECTION; LINEAR MODELS; MALE; PHENYLETHYL ALCOHOL; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84892366542     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3011     Document Type: Article

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