메뉴 건너뛰기




Volumn , Issue , 2009, Pages 31-53

Circulating nucleic acids in plasma and serum: Roles in diagnosis and prognosis

Author keywords

Cancer; Circulating DNA RNA; Diabetes; Diagnosis; Nucleic acid uptake expression; Plasma serum

Indexed keywords


EID: 84892329844     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (3)

References (141)
  • 1
    • 84957852098 scopus 로고
    • Les acides nucléiques du plasma sanguine chez l'homme
    • Mendel P, Métais P (1948) Les acides nucléiques du plasma sanguine chez l'homme. C R Acad. Sci. Paris, 142, 241-243.
    • (1948) C R Acad. Sci. Paris , vol.142 , pp. 241-243
    • Mendel, P.1    Métais, P.2
  • 2
    • 0038497542 scopus 로고
    • A Structure for deoxyribose nucleic acid
    • Watson JD, Crick FH (1953) A Structure for deoxyribose nucleic acid. Nature, 171, 737-738.
    • (1953) Nature , vol.171 , pp. 737-738
    • Watson, J.D.1    Crick, F.H.2
  • 3
    • 36949065046 scopus 로고
    • Molecular structure of deoxypentose nucleic acids
    • Wilkins MH, Stokes AR, Wilson HR (1953) Molecular structure of deoxypentose nucleic acids. Nature, 171, 738-740.
    • (1953) Nature , vol.171 , pp. 738-740
    • Wilkins, M.H.1    Stokes, A.R.2    Wilson, H.R.3
  • 4
    • 0012980681 scopus 로고
    • First steps toward a genetic chemistry
    • Sinsheimer RL (1957) First steps toward a genetic chemistry. Science, 125, 1123-1128.
    • (1957) Science , vol.125 , pp. 1123-1128
    • Sinsheimer, R.L.1
  • 5
    • 0015535196 scopus 로고
    • The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythrematosus and other diseases
    • Koffler D, Agnello V, Winchester R (1973) The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythrematosus and other diseases. J. Clin. Invest., 52, 198-204.
    • (1973) J. Clin. Invest. , vol.52 , pp. 198-204
    • Koffler, D.1    Agnello, V.2    Winchester, R.3
  • 6
    • 0013964845 scopus 로고
    • Deoxyribonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythrematosus
    • Tan EM, Schur PH, Carr RI, Kunkel HG (1966) Deoxyribonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythrematosus. J. Clin. Invest., 45, 1732-1740.
    • (1966) J. Clin. Invest. , vol.45 , pp. 1732-1740
    • Tan, E.M.1    Schur, P.H.2    Carr, R.I.3    Kunkel, H.G.4
  • 7
    • 0017360626 scopus 로고
    • Free DNA in the serum of cancer patients and the effect of therapy
    • Leon SA, Shapiro B, Sklaroff DM, Yaros MJ (1977) Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res., 37, 646-650.
    • (1977) Cancer Res. , vol.37 , pp. 646-650
    • Leon, S.A.1    Shapiro, B.2    Sklaroff, D.M.3    Yaros, M.J.4
  • 8
  • 9
    • 0041366022 scopus 로고    scopus 로고
    • Time course of early and late changes in plasma DNA in trauma patients
    • Lam NY, Rainer TH, Chan LY, Joynt GM, Lo YM (2003) Time course of early and late changes in plasma DNA in trauma patients. Clin. Chem., 49, 1286-1291.
    • (2003) Clin. Chem. , vol.49 , pp. 1286-1291
    • Lam, N.Y.1    Rainer, T.H.2    Chan, L.Y.3    Joynt, G.M.4    Lo, Y.M.5
  • 10
    • 33749548816 scopus 로고    scopus 로고
    • Circulating nucleic acids and critical illness
    • Rainer TH, Lam NY (2006) Circulating nucleic acids and critical illness. Ann. N. Y. Acad. Sci., 1075, 271-277.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1075 , pp. 271-277
    • Rainer, T.H.1    Lam, N.Y.2
  • 16
    • 2642540027 scopus 로고    scopus 로고
    • Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms
    • Li Y, Zimmermann B, Rusterholz C, Kang A, Holzgreve W, Hahn S (2004) Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms. Clin. Chem., 50, 1002-1011.
    • (2004) Clin. Chem. , vol.50 , pp. 1002-1011
    • Li, Y.1    Zimmermann, B.2    Rusterholz, C.3    Kang, A.4    Holzgreve, W.5    Hahn, S.6
  • 18
    • 3242691320 scopus 로고    scopus 로고
    • A clinical service in the UK to predict fetal Rh (Rhesus) D blood group using free fetal DNA in maternal plasma
    • Finning K, Martin P, Daniels G (2004) A clinical service in the UK to predict fetal Rh (Rhesus) D blood group using free fetal DNA in maternal plasma. Ann. N. Y. Acad. Sci., 1022, 119-124.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1022 , pp. 119-124
    • Finning, K.1    Martin, P.2    Daniels, G.3
  • 21
    • 13844269123 scopus 로고    scopus 로고
    • Detection of paternally inherited fetal point mutations for beta-thalassemia using size-fractionated cell-free DNA in maternal plasma
    • Li Y, Di Naro E, Vitucci A, Zimmermann B, Holzgreve W, Hahn S (2005) Detection of paternally inherited fetal point mutations for beta-thalassemia using size-fractionated cell-free DNA in maternal plasma. JAMA, 293, 843-849.
    • (2005) JAMA , vol.293 , pp. 843-849
    • Li, Y.1    Di Naro, E.2    Vitucci, A.3    Zimmermann, B.4    Holzgreve, W.5    Hahn, S.6
  • 23
    • 33749578083 scopus 로고    scopus 로고
    • Noninvasive prenatal diagnotic assay for the detection of ß-thalassemia
    • Papasavva T, Kalikas I, Kyrri A, Kleanthous M (2006) Noninvasive prenatal diagnotic assay for the detection of ß-thalassemia. Ann. N. Y. Acad. Sci., 1075, 148-153.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1075 , pp. 148-153
    • Papasavva, T.1    Kalikas, I.2    Kyrri, A.3    Kleanthous, M.4
  • 24
    • 33845476677 scopus 로고    scopus 로고
    • Circulating nucleic acids (CNAs) and cancer: a survey
    • Fleischhacker M, Schmidt B (2007) Circulating nucleic acids (CNAs) and cancer: a survey. Biochim. Biophys. Acta, 1775, 181-232.
    • (2007) Biochim. Biophys. Acta , vol.1775 , pp. 181-232
    • Fleischhacker, M.1    Schmidt, B.2
  • 25
    • 33749568553 scopus 로고    scopus 로고
    • Concentrations of circulating RNA from healthy donors and cancer patients estimated by different methods
    • Rykova EY, Bryzgunova OE, Skvortsova TE, Tamkovich TN, Senin IN (2006) Concentrations of circulating RNA from healthy donors and cancer patients estimated by different methods. Ann. N. Y. Acad. Sci., 1075, 328-333.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1075 , pp. 328-333
    • Rykova, E.Y.1    Bryzgunova, O.E.2    Skvortsova, T.E.3    Tamkovich, T.N.4    Senin, I.N.5
  • 28
    • 17644393549 scopus 로고    scopus 로고
    • DNA degradation in development and programmed cell death
    • Nagata S (2005) DNA degradation in development and programmed cell death. Ann. Rev. Immunol., 23, 853-875.
    • (2005) Ann. Rev. Immunol. , vol.23 , pp. 853-875
    • Nagata, S.1
  • 29
    • 0035866393 scopus 로고    scopus 로고
    • DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells
    • Jahr S, Hentze H, Englisch S, Hardt D, Fackelmeyer FO, Hesch RD, Knippers R (2001) DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res., 61, 1659-1665.
    • (2001) Cancer Res. , vol.61 , pp. 1659-1665
    • Jahr, S.1    Hentze, H.2    Englisch, S.3    Hardt, D.4    Fackelmeyer, F.O.5    Hesch, R.D.6    Knippers, R.7
  • 30
    • 8844271819 scopus 로고    scopus 로고
    • The immune response to cell death in SLE
    • Pisetsky DS (2004) The immune response to cell death in SLE. Autoimmun. Rev., 3, 500-504.
    • (2004) Autoimmun. Rev. , vol.3 , pp. 500-504
    • Pisetsky, D.S.1
  • 31
    • 0031819579 scopus 로고    scopus 로고
    • Apoptosis: the importance of being eaten
    • Ren Y, Savill J (1998) Apoptosis: the importance of being eaten. Cell Death Differ, 5, 563-568.
    • (1998) Cell Death Differ , vol.5 , pp. 563-568
    • Ren, Y.1    Savill, J.2
  • 34
    • 15444379961 scopus 로고    scopus 로고
    • Assay for the quantification of small-sized fragmented genomic DNA
    • Georgiou CD, Patsoukis N, Papapostolou I (2005) Assay for the quantification of small-sized fragmented genomic DNA. Anal. Biochem., 339, 223-230.
    • (2005) Anal. Biochem. , vol.339 , pp. 223-230
    • Georgiou, C.D.1    Patsoukis, N.2    Papapostolou, I.3
  • 40
    • 0015370111 scopus 로고
    • Excretion of deoxyribonucleic acid by lymphocytes stimulated with phytohemagglutinin or antigen
    • Rogers JC, Boldt D, Kornfeld S, Skinner A, Valeri CR (1972) Excretion of deoxyribonucleic acid by lymphocytes stimulated with phytohemagglutinin or antigen. Proc. Natl. Acad. Sci. U.S.A., 69, 1685-1689.
    • (1972) Proc. Natl. Acad. Sci. U.S.A. , vol.69 , pp. 1685-1689
    • Rogers, J.C.1    Boldt, D.2    Kornfeld, S.3    Skinner, A.4    Valeri, C.R.5
  • 41
    • 0016764251 scopus 로고
    • Spontaneous release of DNA by human blood lymphocytes as shown in an in vitro system
    • Anker P, Stroun M, Maurice PA (1975) Spontaneous release of DNA by human blood lymphocytes as shown in an in vitro system. Cancer Res., 35, 2375-2382.
    • (1975) Cancer Res. , vol.35 , pp. 2375-2382
    • Anker, P.1    Stroun, M.2    Maurice, P.A.3
  • 42
    • 0016347165 scopus 로고
    • Uptake and release of DNA by lymphoid tissue and cells
    • Olsen I, Harris G (1974) Uptake and release of DNA by lymphoid tissue and cells. Immunology, 27, 973-987.
    • (1974) Immunology , vol.27 , pp. 973-987
    • Olsen, I.1    Harris, G.2
  • 43
    • 0019953963 scopus 로고
    • Stimulated and non-stimulated rat spleen cells release different DNA-complexes
    • Adams DH, Gahan PB (1982) Stimulated and non-stimulated rat spleen cells release different DNA-complexes. Differentiation, 22, 47-52.
    • (1982) Differentiation , vol.22 , pp. 47-52
    • Adams, D.H.1    Gahan, P.B.2
  • 44
    • 0020580227 scopus 로고
    • The DNA extruded by rat spleen cells in culture
    • Adams DH, Gahan PB (1983) The DNA extruded by rat spleen cells in culture. Int. J. Biochem., 15, 547-552.
    • (1983) Int. J. Biochem. , vol.15 , pp. 547-552
    • Adams, D.H.1    Gahan, P.B.2
  • 45
    • 0001308111 scopus 로고
    • Appearance of genetic transforming activity in pneumococcal cultures
    • Ottolenghi E, Hotchkiss RD (1960) Appearance of genetic transforming activity in pneumococcal cultures. Science, 132, 1257-1258.
    • (1960) Science , vol.132 , pp. 1257-1258
    • Ottolenghi, E.1    Hotchkiss, R.D.2
  • 46
    • 0000612766 scopus 로고
    • Release of genetic transforming agent from pneumococcal cultures during growth and disintegration
    • Ottolenghi E, Hotchkiss RD (1962) Release of genetic transforming agent from pneumococcal cultures during growth and disintegration. J. Exp. Med., 116, 491-519.
    • (1962) J. Exp. Med. , vol.116 , pp. 491-519
    • Ottolenghi, E.1    Hotchkiss, R.D.2
  • 47
    • 0014675054 scopus 로고
    • Spontaneous release of DNA in sequential genetic order by Bacillus subtilis
    • Borenstein S, Ephrati-Elizur E (1969) Spontaneous release of DNA in sequential genetic order by Bacillus subtilis. J. Mol. Biol., 45, 137-152.
    • (1969) J. Mol. Biol. , vol.45 , pp. 137-152
    • Borenstein, S.1    Ephrati-Elizur, E.2
  • 48
  • 49
    • 0030842849 scopus 로고    scopus 로고
    • In vitro stimulation by tumour cell media of [3H]-thymidine incorporation by mouse spleen lymphocytes
    • Adams DH, Diaz N, Gahan PB (1997) In vitro stimulation by tumour cell media of [3H]-thymidine incorporation by mouse spleen lymphocytes. Cell Biochem. Funct., 15, 119-126.
    • (1997) Cell Biochem. Funct. , vol.15 , pp. 119-126
    • Adams, D.H.1    Diaz, N.2    Gahan, P.B.3
  • 50
    • 0021972803 scopus 로고
    • Studies on the cytosolic DNA of chick embryo fibroblasts and its uptake by recipient cultured cells
    • Adams DH, McIntosh AA (1985) Studies on the cytosolic DNA of chick embryo fibroblasts and its uptake by recipient cultured cells. Int. J. Biochem., 17, 1041-1051.
    • (1985) Int. J. Biochem. , vol.17 , pp. 1041-1051
    • Adams, D.H.1    McIntosh, A.A.2
  • 51
    • 0015447774 scopus 로고
    • In vitro synthesis of DNA spontaneously released by bacteria or frog auricles
    • Stroun M, Anker P (1972) In vitro synthesis of DNA spontaneously released by bacteria or frog auricles. Biochimie, 54, 1443-1452.
    • (1972) Biochimie , vol.54 , pp. 1443-1452
    • Stroun, M.1    Anker, P.2
  • 52
    • 0015363170 scopus 로고
    • Nucleic acids spontaneously released by living frog auricles
    • Stroun M, Anker P (1972) Nucleic acids spontaneously released by living frog auricles. Biochem. J., 128, 100P-101P.
    • (1972) Biochem. J. , vol.128
    • Stroun, M.1    Anker, P.2
  • 53
    • 0001220940 scopus 로고
    • Spontaneous release of newly synthesized DNA from frog auricles
    • Stroun M, Anker P, Gahan PB, Henri J (1977) Spontaneous release of newly synthesized DNA from frog auricles. Arch. Sci. Genève, 30, 229-241.
    • (1977) Arch. Sci. Genève , vol.30 , pp. 229-241
    • Stroun, M.1    Anker, P.2    Gahan, P.B.3    Henri, J.4
  • 54
    • 0013639565 scopus 로고
    • Spontaneous extra-cellular synthesis of DNA released by frog auricles
    • Anker P, Stroun M (1977) Spontaneous extra-cellular synthesis of DNA released by frog auricles. Arch. Sci. Genève, 30, 263-278.
    • (1977) Arch. Sci. Genève , vol.30 , pp. 263-278
    • Anker, P.1    Stroun, M.2
  • 55
    • 0042734866 scopus 로고    scopus 로고
    • Messenger DNA in higher plants
    • Gahan PB (2003) Messenger DNA in higher plants. Cell Biochem. Function, 21, 207-209.
    • (2003) Cell Biochem. Function , vol.21 , pp. 207-209
    • Gahan, P.B.1
  • 56
    • 0015212980 scopus 로고
    • On the nature of the polymerase responsible for the transcription of released bacterial DNA
    • Stroun M (1971) On the nature of the polymerase responsible for the transcription of released bacterial DNA. Biochem. Biophys. Res. Commun., 44, 571-578.
    • (1971) Biochem. Biophys. Res. Commun. , vol.44 , pp. 571-578
    • Stroun, M.1
  • 60
    • 52249095547 scopus 로고    scopus 로고
    • Metabolic DNA as the origin of spontaneously released DNA?
    • Gahan PB, Anker P, Stroun M (2008) Metabolic DNA as the origin of spontaneously released DNA? Ann. N. Y. Acad. Sci., 1137, 7-17.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 7-17
    • Gahan, P.B.1    Anker, P.2    Stroun, M.3
  • 61
    • 0014380146 scopus 로고
    • Biological implications of DNA-turnover in higher organisms. Acta Histochem., S8
    • Pelc SR (1968) Biological implications of DNA-turnover in higher organisms. Acta Histochem., S8, 41-52.
    • (1968) Acta Histochem. , pp. 41-52
    • Pelc, S.R.1
  • 62
    • 0015502016 scopus 로고
    • Bacterial ribonucleic acid in the frog brain after a bacterial peritoneal infection
    • Anker P, Stroun M (1972) Bacterial ribonucleic acid in the frog brain after a bacterial peritoneal infection. Science, 178, 621-623.
    • (1972) Science , vol.178 , pp. 621-623
    • Anker, P.1    Stroun, M.2
  • 63
    • 0015612926 scopus 로고
    • Transcription of spontaneously released bacterial deoxyribonucleic acid in frog auricles
    • Stroun M, Anker P (1973) Transcription of spontaneously released bacterial deoxyribonucleic acid in frog auricles. J. Bacteriol., 114, 114-120.
    • (1973) J. Bacteriol. , vol.114 , pp. 114-120
    • Stroun, M.1    Anker, P.2
  • 64
    • 0021326888 scopus 로고
    • Nude mice injected with DNA released by antigen stimulated human T lymphocytes produce specific antibodies expressing human characteristics
    • Anker P, Jachertz D, Maurice PA, Stroun M (1984) Nude mice injected with DNA released by antigen stimulated human T lymphocytes produce specific antibodies expressing human characteristics. Cell Biochem. Funct., 2, 33-37.
    • (1984) Cell Biochem. Funct. , vol.2 , pp. 33-37
    • Anker, P.1    Jachertz, D.2    Maurice, P.A.3    Stroun, M.4
  • 66
    • 52249114714 scopus 로고    scopus 로고
    • Effect of cell-free DNA of patients with cardiomyopathy and rDNA on the frequency of contraction of electrically paced neonatal rat ventricular myocytes in culture
    • Bulicheva N, Fidelina O, Krtumova MN, Neverova M, Bogush A, Bogush M, Roginko O, Veiko N (2008) Effect of cell-free DNA of patients with cardiomyopathy and rDNA on the frequency of contraction of electrically paced neonatal rat ventricular myocytes in culture. Ann. N. Y. Acad. Sci., 1137, 273-277.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 273-277
    • Bulicheva, N.1    Fidelina, O.2    Krtumova, M.N.3    Neverova, M.4    Bogush, A.5    Bogush, M.6    Roginko, O.7    Veiko, N.8
  • 67
    • 52249086733 scopus 로고    scopus 로고
    • Binding and penetration of methylated DNA into primary and transformed human cells
    • Skvortsova TE, Vlassov VV, Laktionov PP (2008) Binding and penetration of methylated DNA into primary and transformed human cells. Ann. N. Y. Acad. Sci., 1137, 36-40.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 36-40
    • Skvortsova, T.E.1    Vlassov, V.V.2    Laktionov, P.P.3
  • 68
    • 1842611093 scopus 로고    scopus 로고
    • Circulating nucleic acids in plasma and serum (CNAPS) and its relation to stem cells and cancer metastasis: state of the issue
    • Garcia-Olmo DC, Ruiz-Piqueras R, Garcia-Olmo D (2004) Circulating nucleic acids in plasma and serum (CNAPS) and its relation to stem cells and cancer metastasis: state of the issue. Histol. Histopathol., 19, 575-583.
    • (2004) Histol. Histopathol. , vol.19 , pp. 575-583
    • Garcia-Olmo, D.C.1    Ruiz-Piqueras, R.2    Garcia-Olmo, D.3
  • 69
    • 0032802166 scopus 로고    scopus 로고
    • Detection of tumor messenger. RNA in the serum of patients with malignant melanoma.
    • Kopreski MS, Benko FA, Kwak LW, Gocke CD (1999) Detection of tumor messenger. RNA in the serum of patients with malignant melanoma. Clin. Cancer Res., 5, 1961-1965.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1961-1965
    • Kopreski, M.S.1    Benko, F.A.2    Kwak, L.W.3    Gocke, C.D.4
  • 70
    • 0036282415 scopus 로고    scopus 로고
    • Detection of epithelial tumor RNA in the plasma of colon cancer patients is associated with advanced stages and circulating tumour cells
    • Silva JM, Rodriguez R, Garcia JM, Muñoz C, Silva J, Dominguez G, Provencio M, España P, Bonilla F (2002) Detection of epithelial tumor RNA in the plasma of colon cancer patients is associated with advanced stages and circulating tumour cells. Gut, 50, 530-534.
    • (2002) Gut , vol.50 , pp. 530-534
    • Silva, J.M.1    Rodriguez, R.2    Garcia, J.M.3    Muñoz, C.4    Silva, J.5    Dominguez, G.6    Provencio, M.7    España, P.8    Bonilla, F.9
  • 71
    • 1542328938 scopus 로고    scopus 로고
    • Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics
    • El-Hefnawy T, Raja S, Kelly L, Bigbee WL, Kirkwood JM, Luketich JD, Godfrey TE (2004) Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics. Clin. Chem., 50, 564-573.
    • (2004) Clin. Chem. , vol.50 , pp. 564-573
    • El-Hefnawy, T.1    Raja, S.2    Kelly, L.3    Bigbee, W.L.4    Kirkwood, J.M.5    Luketich, J.D.6    Godfrey, T.E.7
  • 74
    • 0035022174 scopus 로고    scopus 로고
    • Real-time quantification in plasma of human telomerase reverse transcriptase (hTERT) mRNA: a simple blood test to monitor disease in cancer patients
    • Dasí F, Lledó S, García-Granero E, Ripoll R, Marugán E, Tormo M, García-Conde J, Aliño SF (2001) Real-time quantification in plasma of human telomerase reverse transcriptase (hTERT) mRNA: a simple blood test to monitor disease in cancer patients. Lab. Invest., 81, 767-769.
    • (2001) Lab. Invest. , vol.81 , pp. 767-769
    • Dasí, F.1    Lledó, S.2    García-Granero, E.3    Ripoll, R.4    Marugán, E.5    Tormo, M.6    García-Conde, J.7    Aliño, S.F.8
  • 75
    • 0034926031 scopus 로고    scopus 로고
    • Extracellular tyrosinase mRNA within apoptotic bodies is protected from degradation in human serum
    • Hasselman DO, Rappl G, Tilgen W, Reinhold U (2001) Extracellular tyrosinase mRNA within apoptotic bodies is protected from degradation in human serum. Clin. Chem., 47, 1488-1489.
    • (2001) Clin. Chem. , vol.47 , pp. 1488-1489
    • Hasselman, D.O.1    Rappl, G.2    Tilgen, W.3    Reinhold, U.4
  • 77
    • 0018081012 scopus 로고
    • Presence of RNA in the nucleoprotein complex spontaneously released by human lymphocytes and frog auricles in culture
    • Stroun M, Anker P, Beljanski M, Henri J, Lederrey C, Ojha M, Maurice P (1978) Presence of RNA in the nucleoprotein complex spontaneously released by human lymphocytes and frog auricles in culture. Cancer Res., 38, 3546-3554.
    • (1978) Cancer Res. , vol.38 , pp. 3546-3554
    • Stroun, M.1    Anker, P.2    Beljanski, M.3    Henri, J.4    Lederrey, C.5    Ojha, M.6    Maurice, P.7
  • 78
    • 0015212980 scopus 로고
    • On the nature of the polymerase responsible for the transcription of released bacterial DNA in plant cells
    • Stroun M (1971) On the nature of the polymerase responsible for the transcription of released bacterial DNA in plant cells. Biochem. Biophys. Res. Commun., 44, 571-578.
    • (1971) Biochem. Biophys. Res. Commun. , vol.44 , pp. 571-578
    • Stroun, M.1
  • 82
    • 0015040370 scopus 로고
    • Evidence for transfer of macromolecular RNA between mammalian cells in culture
    • Kolodny GM (1971) Evidence for transfer of macromolecular RNA between mammalian cells in culture. Exp. Cell Res., 65, 313-324.
    • (1971) Exp. Cell Res. , vol.65 , pp. 313-324
    • Kolodny, G.M.1
  • 84
    • 0037192490 scopus 로고    scopus 로고
    • Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.
    • Winston WM, Molodowitch C, Hunter CP (2002) Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science, 295, 2456-2459.
    • (2002) Science , vol.295 , pp. 2456-2459
    • Winston, W.M.1    Molodowitch, C.2    Hunter, C.P.3
  • 86
    • 33746608192 scopus 로고    scopus 로고
    • The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing
    • Saleh MC, van Rij RP, Hekele A, Gillis A, Foley E (2006) The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat. Cell Biol., 8, 793-802.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 793-802
    • Saleh, M.C.1    van Rij, R.P.2    Hekele, A.3    Gillis, A.4    Foley, E.5
  • 90
  • 91
    • 0036794062 scopus 로고    scopus 로고
    • Stability of endogenous and added RNA in blood specimens, serum, and plasma
    • Tsui NB, Ng EK, Lo YM (2002) Stability of endogenous and added RNA in blood specimens, serum, and plasma. Clin. Chem., 48, 1647-1653.
    • (2002) Clin. Chem. , vol.48 , pp. 1647-1653
    • Tsui, N.B.1    Ng, E.K.2    Lo, Y.M.3
  • 93
    • 0141672711 scopus 로고
    • Elevated serum ribonuclease in patients with pancreatic cancer
    • Reddi KK, Holland JF (1976) Elevated serum ribonuclease in patients with pancreatic cancer. Proc. Nat. Acad. Sci. U.S.A., 73, 2308-2310.
    • (1976) Proc. Nat. Acad. Sci. U.S.A. , vol.73 , pp. 2308-2310
    • Reddi, K.K.1    Holland, J.F.2
  • 97
    • 33749567633 scopus 로고    scopus 로고
    • Circulating nucleic acids in plasma and serum: recent developments
    • Swaminathan R, Butt A (2006) Circulating nucleic acids in plasma and serum: recent developments. Ann. N. Y. Acad. Sci., 1075, 1-9.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1075 , pp. 1-9
    • Swaminathan, R.1    Butt, A.2
  • 98
    • 25444514462 scopus 로고    scopus 로고
    • Circulating placental RNA in maternal plasma is associated with a preponderance of 5' mRNA fragments: Implications for noninvasive prenatal diagnosis and monitoring
    • Wong BC, Chiu RW, Tsui NB, Chan KC, Chan LW, Lau TK, Leung TN, Lo YM (2005) Circulating placental RNA in maternal plasma is associated with a preponderance of 5' mRNA fragments: Implications for noninvasive prenatal diagnosis and monitoring. Clin. Chem., 51, 1786-1795.
    • (2005) Clin. Chem. , vol.51 , pp. 1786-1795
    • Wong, B.C.1    Chiu, R.W.2    Tsui, N.B.3    Chan, K.C.4    Chan, L.W.5    Lau, T.K.6    Leung, T.N.7    Lo, Y.M.8
  • 100
    • 14544285000 scopus 로고    scopus 로고
    • Lack of dramatic enrichment of fetal DNA in maternal plasma by formaldehyde treatment
    • Chung GT, Chiu RW, Chan KC, Lau TK (2005) Lack of dramatic enrichment of fetal DNA in maternal plasma by formaldehyde treatment. Clin. Chem., 51, 655-658.
    • (2005) Clin. Chem. , vol.51 , pp. 655-658
    • Chung, G.T.1    Chiu, R.W.2    Chan, K.C.3    Lau, T.K.4
  • 101
    • 14544292428 scopus 로고    scopus 로고
    • Treatment of maternal blood samples with formaldehyde does not alter the proportion of circulatory fetal nucleic acids (DNA and mRNA) in maternal plasma
    • Chinnapapagari SK, Holzgreve W, Lapaire O, Zimmermann B, Hahn S (2005) Treatment of maternal blood samples with formaldehyde does not alter the proportion of circulatory fetal nucleic acids (DNA and mRNA) in maternal plasma. Clin. Chem., 51, 652-655.
    • (2005) Clin. Chem. , vol.51 , pp. 652-655
    • Chinnapapagari, S.K.1    Holzgreve, W.2    Lapaire, O.3    Zimmermann, B.4    Hahn, S.5
  • 102
    • 52249093579 scopus 로고    scopus 로고
    • Fetal nucleic acids in maternal plasma: toward the development of a noninvasive prenatal diagnosis of fetal chomosomal aneuploidies
    • Lo YM (2008) Fetal nucleic acids in maternal plasma: toward the development of a noninvasive prenatal diagnosis of fetal chomosomal aneuploidies. Ann. N. Y. Acad. Sci., 1137, 140-143.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 140-143
    • Lo, Y.M.1
  • 104
    • 52249122641 scopus 로고    scopus 로고
    • Arrayed primer extension for the noninvasive prenatal diagnosis of ß-thalassemia based on detection of single nucleotide polymorphisms
    • Papasavva T, Kalikas I, Kyrri A, Kleanthous M (2008) Arrayed primer extension for the noninvasive prenatal diagnosis of ß-thalassemia based on detection of single nucleotide polymorphisms. Ann. N. Y. Acad. Sci., 1137, 302-308.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 302-308
    • Papasavva, T.1    Kalikas, I.2    Kyrri, A.3    Kleanthous, M.4
  • 107
    • 15044344343 scopus 로고    scopus 로고
    • Function of the protein RPE65 in the visual cycle
    • Wolf G (2005) Function of the protein RPE65 in the visual cycle. Nutr. Rev., 63, 97-100.
    • (2005) Nutr. Rev. , vol.63 , pp. 97-100
    • Wolf, G.1
  • 108
    • 33845772137 scopus 로고    scopus 로고
    • Focus on molecules: retinoschisin (RS1)
    • Molday RS (2007) Focus on molecules: retinoschisin (RS1). Exp. Eye Res., 84, 227-228.
    • (2007) Exp. Eye Res. , vol.84 , pp. 227-228
    • Molday, R.S.1
  • 109
    • 31444456318 scopus 로고    scopus 로고
    • Melanopsin: another way of signaling light
    • Peirson S, Foster RG (2006) Melanopsin: another way of signaling light. Neuron, 49, 331-339.
    • (2006) Neuron , vol.49 , pp. 331-339
    • Peirson, S.1    Foster, R.G.2
  • 110
    • 33646713706 scopus 로고    scopus 로고
    • Regulation of melanopsin expression
    • Hannibal J (2006) Regulation of melanopsin expression. Chronobiol. Int., 23, 159-166.
    • (2006) Chronobiol. Int. , vol.23 , pp. 159-166
    • Hannibal, J.1
  • 111
    • 52249093371 scopus 로고    scopus 로고
    • Effect of hypoxia on circulating levels of retina-specific messenger RNA in type 2 diabetes
    • Wong A, Merritt S, Butt AN, Williams A, Swaminathan R (2008) Effect of hypoxia on circulating levels of retina-specific messenger RNA in type 2 diabetes. Ann. N. Y. Acad. Sci., 1137, 243-252.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 243-252
    • Wong, A.1    Merritt, S.2    Butt, A.N.3    Williams, A.4    Swaminathan, R.5
  • 112
    • 52249118786 scopus 로고    scopus 로고
    • Measurement of circulating neuron specific enolase mRNA in Diabetes Mellitus
    • Sandhu HS, Butt AN, Powrie J, Swaminathan R (2008) Measurement of circulating neuron specific enolase mRNA in Diabetes Mellitus. Ann. N. Y. Acad. Sci., 1137, 258-263.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 258-263
    • Sandhu, H.S.1    Butt, A.N.2    Powrie, J.3    Swaminathan, R.4
  • 115
    • 0023161086 scopus 로고
    • Neuron specific enolase, a clinically useful marker for neurons and neuroendocrine cells
    • Marangos PJ, Schmechel DE (1987) Neuron specific enolase, a clinically useful marker for neurons and neuroendocrine cells. Ann. Rev. Neurosci., 10, 269-295.
    • (1987) Ann. Rev. Neurosci. , vol.10 , pp. 269-295
    • Marangos, P.J.1    Schmechel, D.E.2
  • 116
    • 0020083446 scopus 로고
    • Distribution of nervous system-specific forms of enolase in peripheral. tissues.
    • Kato K, Ishiguro Y, Suzuki F, Ito A, Semba R (1982) Distribution of nervous system-specific forms of enolase in peripheral. tissues. Brain Res., 237, 441-448.
    • (1982) Brain Res. , vol.237 , pp. 441-448
    • Kato, K.1    Ishiguro, Y.2    Suzuki, F.3    Ito, A.4    Semba, R.5
  • 118
    • 0021031758 scopus 로고
    • Nervous system-specific enolase in serum as a marker for neuroblastoma
    • Ishiguro Y, Kato K, Ito T, Nagaya M, Yamada N, Sugito T (1983) Nervous system-specific enolase in serum as a marker for neuroblastoma. Pediatrics, 72, 696-700.
    • (1983) Pediatrics , vol.72 , pp. 696-700
    • Ishiguro, Y.1    Kato, K.2    Ito, T.3    Nagaya, M.4    Yamada, N.5    Sugito, T.6
  • 121
    • 14644445182 scopus 로고    scopus 로고
    • Prospective study of quantitation of plasma DNA levels in the diagnosis of malignant versus benign prostate disease
    • Boddy JL, Gal S, Malone PR, Harris AL, Wainscoat JS (2005) Prospective study of quantitation of plasma DNA levels in the diagnosis of malignant versus benign prostate disease. Clin. Cancer Res., 11, 1394-1399.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 1394-1399
    • Boddy, J.L.1    Gal, S.2    Malone, P.R.3    Harris, A.L.4    Wainscoat, J.S.5
  • 123
    • 52249115644 scopus 로고    scopus 로고
    • Integrity of cell-free plasma DNA in patients with lung cancer and nonmalignant lung disease
    • Schmidt B, Weickmann S, Witt C, Fleischhacker M (2008) Integrity of cell-free plasma DNA in patients with lung cancer and nonmalignant lung disease. Ann. N. Y. Acad. Sci., 1137, 207-213.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 207-213
    • Schmidt, B.1    Weickmann, S.2    Witt, C.3    Fleischhacker, M.4
  • 125
    • 0034055893 scopus 로고    scopus 로고
    • A review of studies on the detection of mutated KRAS2 sequences as tumor markers in plasma/serum of patients with gastrointestinal cancer
    • Sorenson GD (2000) A review of studies on the detection of mutated KRAS2 sequences as tumor markers in plasma/serum of patients with gastrointestinal cancer. Ann. N. Y. Acad. Sci., 906, 13-16.
    • (2000) Ann. N. Y. Acad. Sci. , vol.906 , pp. 13-16
    • Sorenson, G.D.1
  • 126
    • 52249114928 scopus 로고    scopus 로고
    • Removal of high molecular weight DNA by carboxylate magnetic beads enhances the detection of mutated K-ras DNA in urine
    • Su YH, Song J, Wang Z, WangXH, Wang M, Brenner DE, Block TM (2008) Removal of high molecular weight DNA by carboxylate magnetic beads enhances the detection of mutated K-ras DNA in urine. Ann. N. Y. Acad. Sci., 1137, 82-91.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 82-91
    • Su, Y.H.1    Song, J.2    Wang, Z.3    Wang, X.H.4    Wang, M.5    Brenner, D.E.6    Block, T.M.7
  • 129
    • 52249087563 scopus 로고    scopus 로고
    • Detection and monitoring of cell-free DNA in blood of patients with colorectal cancer
    • Schwarzenbach H, Stoehlmacher J, Pantel K, Goekkurt E (2008) Detection and monitoring of cell-free DNA in blood of patients with colorectal cancer. Ann. N. Y. Acad. Sci., 1137, 190-196.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 190-196
    • Schwarzenbach, H.1    Stoehlmacher, J.2    Pantel, K.3    Goekkurt, E.4
  • 130
    • 33749557860 scopus 로고    scopus 로고
    • Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients
    • Taback B, Saha S, Hoon DS (2006) Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients. Ann. N. Y. Acad. Sci., 1075, 197-203.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1075 , pp. 197-203
    • Taback, B.1    Saha, S.2    Hoon, D.S.3
  • 132
    • 52249118141 scopus 로고    scopus 로고
    • Methylation-specific sequencing of GSTP1 gene promoter in circulating/extracellular DNA from blood and urine of healthy donors and prostate cancer patients
    • Bryzgunova OE, Morozkin ES, Yarmoschuk SV, Vlassov VV, Laktionov PP (2008) Methylation-specific sequencing of GSTP1 gene promoter in circulating/extracellular DNA from blood and urine of healthy donors and prostate cancer patients. Ann. N. Y. Acad. Sci., 1137, 222-225.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 222-225
    • Bryzgunova, O.E.1    Morozkin, E.S.2    Yarmoschuk, S.V.3    Vlassov, V.V.4    Laktionov, P.P.5
  • 133
    • 33749576333 scopus 로고    scopus 로고
    • Comparison of genetic alterations detected in circulating microsatellite DNA in blood plasma samples of patients with prostate cancer and benign prostatic hyperplasia
    • Müller I, Urban K, Pantel K, Schwarztenbach H (2006) Comparison of genetic alterations detected in circulating microsatellite DNA in blood plasma samples of patients with prostate cancer and benign prostatic hyperplasia. Ann. N. Y. Acad. Sci., 1075, 222-229.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1075 , pp. 222-229
    • Müller, I.1    Urban, K.2    Pantel, K.3    Schwarztenbach, H.4
  • 135
    • 30144434924 scopus 로고    scopus 로고
    • Plasma DNA as a prognostic marker for stroke patients with negative neuroimaging within the first 24h of symptom onset
    • Lam NY, Rainer TH, Wong LK, Lam W, Lo YM (2006) Plasma DNA as a prognostic marker for stroke patients with negative neuroimaging within the first 24h of symptom onset. Resuscitation, 68, 71-78.
    • (2006) Resuscitation , vol.68 , pp. 71-78
    • Lam, N.Y.1    Rainer, T.H.2    Wong, L.K.3    Lam, W.4    Lo, Y.M.5
  • 136
    • 0034751458 scopus 로고    scopus 로고
    • Derivation of a prediction rule for posttraumatic organ failure using plasma DNA and other variables
    • Rainer TH, Lo YM, Chan LY, Lam NY, Lit LC, Cocks RA (2001) Derivation of a prediction rule for posttraumatic organ failure using plasma DNA and other variables. Ann. N. Y. Acad. Sci., 945, 211-220.
    • (2001) Ann. N. Y. Acad. Sci. , vol.945 , pp. 211-220
    • Rainer, T.H.1    Lo, Y.M.2    Chan, L.Y.3    Lam, N.Y.4    Lit, L.C.5    Cocks, R.A.6
  • 137
    • 0037381516 scopus 로고    scopus 로고
    • Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke
    • Rainer TH, Wong LK, Lam W, Yuin E, Lam NY, Metreweli C, Lo YM (2003) Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke. Clin. Chem., 49, 562-569.
    • (2003) Clin. Chem. , vol.49 , pp. 562-569
    • Rainer, T.H.1    Wong, L.K.2    Lam, W.3    Yuin, E.4    Lam, N.Y.5    Metreweli, C.6    Lo, Y.M.7
  • 138
    • 52249092649 scopus 로고    scopus 로고
    • Circulating 11 ß-hydroxysteroid dehydrogenase Type I mRNA and cardiovascular risk factors
    • Al Bakir M, Butt AN, Swaminathan R (2008) Circulating 11 ß-hydroxysteroid dehydrogenase Type I mRNA and cardiovascular risk factors. Ann. N. Y. Acad. Sci., 1137, 283-289.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 283-289
    • Al Bakir, M.1    Butt, A.N.2    Swaminathan, R.3
  • 139
    • 52249109596 scopus 로고    scopus 로고
    • Hypertension and circulating mRNA for 11 ß-hydroxysteroid dehydrogenase Type II
    • Agalou S, Butt A, Chowienczyk P, Swaminathan R (2008) Hypertension and circulating mRNA for 11 ß-hydroxysteroid dehydrogenase Type II. Ann. N. Y. Acad. Sci., 1137, 290-295.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 290-295
    • Agalou, S.1    Butt, A.2    Chowienczyk, P.3    Swaminathan, R.4
  • 140
    • 52249105352 scopus 로고    scopus 로고
    • Circulating nucleic acids in the assessment of endogenous growth hormone production
    • Thakkar H, Butt AN, Powrie J, Holt R, Swaminathan R (2008) Circulating nucleic acids in the assessment of endogenous growth hormone production. Ann. N. Y. Acad. Sci., 1137, 58-65.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1137 , pp. 58-65
    • Thakkar, H.1    Butt, A.N.2    Powrie, J.3    Holt, R.4    Swaminathan, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.