Clinical research and outcomes research: Common criteria and differences

Optimizing Health: Improving the Value of Healthcare Delivery

Volumn , Issue , 2006, Pages 257-264

  Porzsolt, Franz ^a   Stengel, Dirk ^b   Ghosh, Amit K ^c   Kaplan, Robert M ^d  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b Clinical Epidemiology Division   (Germany)

^c Mayo Clinic College of Medicine   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84892206109     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-33921-4_26     Document Type: Chapter

References (21)

1. American Society of Clinical Oncology (1996). Outcomes of cancer treatment for technology assessment and cancer treatment guidelines. Journal of Clinical Oncology, 14, 671-679.
2. Anderson, G.F. (1997). In search of value: an international comparison of cost, access, and outcomes. Health Affairs, 16, 163-171.
3. Anonymous. (1994). Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials. Archives of Internal Medicine, 154, 1449-1457.
4. Apolone, G. (2003). Clinical and outcome research in oncology: the need for integration. Health Quality of Life Outcomes, 1, 3.
5. Bast, R.C., Mills, G.B., Young, R.C. (2001). Translational research: traffic on the bridge. Biomedicine and Pharmacotherapy, 55, 565-571.
6. Contopoulos-Ioannidis, D.G., Ntzani, E., Ioannidis, J.P. (2003). Translation of highly promising basic science research into clinical applications. American Journal of Medicine, 114, 477-484.
7. Johnson, J.R., Williams, G., Pazdur, R. (2003). Endpoints and United States Food and Drug Administration approval of oncology drugs. Journal of Clinical Oncology, 21, 1404-1411.
8. Kravitz, R.L., Duan, N., Braslow, J. (2004). Evidence-based medicine, heterogeneity of treatment effects, and the trouble with averages. Milbank Quarterly, 82, 661-687.
9. Last, JM.(1988). A Dictionary Of Epidemiology. Oxford: Oxford University Press.
10. Last, J. M. (1988). A dictionary of epidemiology. Oxford: Oxford University Press. Lee, S.J., Craig, C.E., Weeks, J.C. (2000). Outcomes research in oncology: history, conceptual framework, and trends in the literature. Journal of National Cancer Institute, 92, 195-204.
11. Lip, G.Y., Lowe, G.D. (1996). ABC of atrial fibrillation: antithrombotic treatment for atrial fibrillation. British Medical Journal, 312, 45-49.
12. Porzsolt, F., Kumpf, J., Coppin, C., Pöppel, E. (2003). Stringent application of epidemiological criteria changes the interpretation of the effects of immunotherapy in advanced renal cell cancer. In: C. Williams, V. Bramwell, X. Bonfill, J. Cuzick, J. Forbes (Eds.), Evidence-based oncology. Oxford: BMJ Books. pp. 34-38.
13. Porzsolt, F., Kojer, M., Schmidl, M., Greimel, E.R., Siegle, J., Richter, J., et al. (2004a). A new instrument to describe indicators of well-being in old-old patients with severe dementia: the Vienna List. Health Quality of Life Outcomes, 2, 10.
14. Porzsolt, F., Schlotz-Gorton, N., Biller-Andorno, N., Thim, A., Meissner, K., Roeckl- Wiedmann, I., et al. (2004b). Applying evidence to support ethical decisions: is the placebo really powerless? Science in Engineering and Ethics, 10, 119-132.
15. Rothwell, P.M. (2005a). External validity of randomised controlled trials: "to whom do the results of this trial apply?" Lancet, 365, 13-14.
16. Rothwell, P.M. (2005b). Treating individuals, 2. Subgroup analysis in randomised controlled trials: importance, indications, and interpretation. Lancet, 365, 176-186.
17. Rothwell, P.M. (2005c). Treating individuals. 3. From subgroups to individuals: general principles and the example of carotid endarterectomy. Lancet, 365, 256-265.
18. Rubin, D.B. (1997). Estimating causal effects from large data sets using propensity scores. Annals of Internal Medicine, 127, 757-763.
19. Schilsky, R.L. (2002). Endpoints in cancer clinical trials and the drugs approval process. Clinical Cancer Research, 8, 935-938.
20. Schmoor, C., Olschewski, M., Schumacher, M. (1996). Randomized and non-randomized patients in clinical trials: experiences with comprehensive cohort studies. Statistics in Medicine, 15, 263-271.
21. Zerhouni, E. (2003). The NIH roadmap. Science, 302, 63-72.