Methylene blue microbubbles as a model dual-modality contrast agent for ultrasound and activatable photoacoustic imaging

Journal of Biomedical Optics

Volumn 19, Issue 1, 2014, Pages

  Jeon, Mansik ^a   Song, Wentao ^b   Huynh, Elizabeth ^c   Kim, Jungho ^d   Kim, Jeesu ^a   Helfield, Brandon L ^c   Leung, Ben Y C ^e   Goertz, David E ^c,d   Zheng, Gang ^c   Oh, Jungtaek ^d   Lovell, Jonathan F ^b   Kim, Chulhong ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b University at Buffalo SUNY   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

^d Medison Co Ltd   (South Korea)

^e SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

activatable photoacoustic imaging; dual modality contrast agent.; methylene blue; microbubbles; ultrasound imaging

Indexed keywords

CONTRAST AGENT; METHYLENE BLUE; MICROBUBBLES; PHOTO-ACOUSTIC IMAGING; ULTRASOUND IMAGING;

AROMATIC COMPOUNDS; PHOTOACOUSTIC EFFECT; ULTRASONIC IMAGING; ULTRASONIC TESTING;

ULTRASONICS;

CONTRAST MEDIUM; METHYLENE BLUE;

ARTICLE; CHEMISTRY; ECHOGRAPHY; EQUIPMENT; IMAGE PROCESSING; METHODOLOGY; MICROBUBBLE; MICROSCOPY; OPTICS; PHOTOACOUSTICS; ULTRASOUND;

CONTRAST MEDIA; IMAGE PROCESSING, COMPUTER-ASSISTED; METHYLENE BLUE; MICROBUBBLES; MICROSCOPY; OPTICS AND PHOTONICS; PHOTOACOUSTIC TECHNIQUES; ULTRASONICS; ULTRASONOGRAPHY;

EID: 84892171715     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.JBO.19.1.016005     Document Type: Article

References (33)

1. P. Beard, "Biomedical photoacoustic imaging," Interface Focus 1(4), 602-631 (2011).
2. C. Kim, C. Favazza, and L. H. V. Wang, "In vivo photoacoustic tomography of chemicals: high-resolution functional and molecular optical imaging at new depths," Chem. Rev. 110(5), 2756-2782 (2010).
3. L. H. V. Wang and S. Hu, "Photoacoustic tomography: in vivo imaging from organelles to organs," Science 335(6075), 1458-1462 (2012).
4. J. Laufer et al., "In vivo preclinical photoacoustic imaging of tumor vasculature development and therapy," J. Biomed. Opt. 17(5), 056016 (2012).
5. J. J. Yao, K. I. Maslov, and L. H. V. Wang, "In vivo photoacoustic tomography of total blood flow and potential imaging of cancer angiogenesis and hypermetabolism," Technol. Cancer Res. Treat. 11(4), 301-307 (2012).
6. J. J. Yao et al., "Noninvasive photoacoustic computed tomography of mouse brain metabolism in vivo," Neuroimage 1(64), 257-266 (2013).
7. J. Laufer et al., "In vivo photoacoustic imaging of mouse embryos," J. Biomed. Opt. 17(6), 061220 (2012).
8. R. J. Zemp et al., "Realtime photoacoustic microscopy of murine cardiovascular dynamics," Opt. Express 16(22), 18551-18556 (2008).
9. S. L. Jiao et al., "Photoacoustic ophthalmoscopy for in vivo retinal imaging," Opt. Express 18(4), 3967-3972 (2010).
10. C. Kim et al., "Performance benchmarks of an array-based hand-held photoacoustic probe adapted from a clinical ultrasound system for noninvasive sentinel lymph node imaging," Philos. Trans. R. Soc. A 369 (1955), 4644-4650 (2011).
11. S. A. Ermilov et al., "Laser optoacoustic imaging system for detection of breast cancer," J. Biomed. Opt. 14(2), 024007 (2009).
12. C. Kim et al., "Sentinel lymph nodes and lymphatic vessels: noninvasive dual-modality in vivo mapping by using indocyanine green in rats-volumetric spectroscopic photoacoustic imaging and planar fluorescence imaging," Radiology 255(2), 442-450 (2010).
13. B. Wang et al., "Photoacoustic tomography and fluorescence molecular tomography: a comparative study based on indocyanine green," Med. Phys. 39(5), 2512-2517 (2012).
14. E. Morgounova et al., "Photoacoustic lifetime contrast between methylene blue monomers and self-quenched dimers as a model for duallabeled activatable probes," J. Biomed. Opt. 18(5), 056004 (2013).
15. X. Cai et al., "In vivo quantitative evaluation of the transport kinetics of gold nanocages in a lymphatic system by noninvasive photoacoustic tomography," ACS Nano 5(12), 9658-9667 (2011).
16. C. Kim et al., "In vivo photoacoustic mapping of lymphatic systems with plasmon-resonant nanostars," J. Mater. Chem. 21(9), 2841-2844 (2011).
17. J. V. Jokerst et al., "Gold nanorods for ovarian cancer detection with photoacoustic imaging and resection guidance via Raman imaging in living mice," ACS Nano 6(11), 10366-10377 (2012).
18. T. Z. H. Qin et al., "Gadolinium(III)-gold nanorods for MRI and photoacoustic imaging dual-modality detection of macrophages in atherosclerotic inflammation," Nanomedicine 8(10), 1611-1624 (2013).
19. J. F. Lovell et al., "Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents," Nat. Mater. 10(4), 324-332 (2011).
20. Z. B. Zha et al., "Biocompatible polypyrrole nanoparticles as a novel organic photoacoustic contrast agent for deep tissue imaging," Nanoscale 5(10), 4462-4467 (2013).
21. C. Kim et al., "Deeply penetrating in vivo photoacoustic imaging using a clinical ultrasound array system," Biomed. Opt. Express 1(1), 278-284 (2010).
22. C. Kim et al., "Handheld array-based photoacoustic probe for guiding needle biopsy of sentinel lymph nodes," J. Biomed. Opt. 15 (4), 046010 (2010).
23. S. R. Wilson and P. N. Burns, "Microbubble-enhanced US in body imaging: what role?," Radiology 257(1), 24-39 (2010).
24. G. M. Lanza and S. A. Wickline, "Targeted ultrasonic contrast agents for molecular imaging and therapy," Curr. Prob. Cardiol. 28(12), 625-653 (2003).
25. J. Song et al., "Stimulation of arteriogenesis in skeletal muscle by microbubble destruction with ultrasound," Circulation 106(12), 1550-1555 (2002).
26. C. Kim et al., "Multifunctional microbubbles and nanobubbles for photoacoustic and ultrasound imaging," J. Biomed. Opt. 15(1), 010510 (2010).
27. Y. H. Wang et al., "Photoacoustic/ultrasound dual-modality contrast agent and its application to thermotherapy," J. Biomed. Opt. 17(4), 045001 (2012).
28. K. Wilson, K. Homan, and S. Emelianov, "Biomedical photoacoustics beyond thermal expansion using triggered nanodroplet vaporization for contrast-enhanced imaging," Nat. Commun. 3(618), 1-10 (2012).
29. E. Huynh et al., "Porphyrin shell microbubbles with intrinsic ultrasound and photoacoustic properties," J. Am. Chem. Soc. 134(40), 16464-16467 (2012).
30. D. E. Goertz, N. de Jong, and A. F. W. van der Steen, "Attenuation and size distributionmeasurements of definity (TM) and manipulated definity (TM) populations," UltrasoundMed. Biol. 33(9), 1376-1388 (2007). (Pubitemid 47302197)
31. C. Kim, M. Jeon, and L. V. Wang, "Nonionizing photoacoustic cystography in vivo," Opt. Lett. 36(18), 3599-3601 (2011).
32. J. M. Gorce, M. Arditi, and M. Schneider, "Influence of bubble size distribution on the echogenicity of ultrasound contrast agents-a study of SonoVue (TM)," Invest. Radiol. 35(11), 661-671 (2000).
33. K. Sarkar et al., "Characterization of ultrasound contrast microbubbles using in vitro experiments and viscous and viscoelastic interface models for encapsulation," J. Acoust. Soc. Am. 118(1), 539-550 (2005). (Pubitemid 40981508)