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Volumn 17, Issue 1, 2014, Pages 34-41

Progress in immunotherapy for non-small cell lung cancer

Author keywords

Checkpoint inhibitors; Immunotherapy; Lung neoplasms; Tumour vaccines

Indexed keywords

CARCINOMA, NON-SMALL-CELL LUNG; CLINICAL TRIALS AS TOPIC; HUMANS; IMMUNOTHERAPY; LUNG NEOPLASMS; TREATMENT OUTCOME;

EID: 84892152423     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: 10.3779/j.issn.1009-3419.2014.01.06     Document Type: Review
Times cited : (3)

References (43)
  • 1
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010
    • Jemal A, Siegel R, Xu J, et al. Cancer statistics, 2010. CA Cancer J Clin, 2010, 60(5): 277-300.
    • (2010) CA Cancer J Clin , vol.60 , Issue.5 , pp. 277-300
    • Jemal, A.1    Siegel, R.2    Xu, J.3
  • 2
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science, 2004, 304(5676): 1497-1500.
    • (2004) Science , vol.304 , Issue.5676 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 3
    • 84940339632 scopus 로고    scopus 로고
    • ed, 2nd ed. Beijing: People Health Publishing House
    • Zeng YX ed. Oncology. 2nd ed. Beijing: People Health Publishing House, 2003. 287-290
    • (2003) Oncology , pp. 287-290
    • Zeng, Y.X.1
  • 4
    • 84865567620 scopus 로고    scopus 로고
    • What future opportunities may immuno-oncology provide for improving the treatment of patients with lung cancer?
    • Reck M. What future opportunities may immuno-oncology provide for improving the treatment of patients with lung cancer? Ann Oncol, 2012, 23 (Suppl 8): viii28-34.
    • (2012) Ann Oncol , vol.23 , Issue.SUPPL. 8
    • Reck, M.1
  • 5
    • 84875936184 scopus 로고    scopus 로고
    • Harnessing the immune system for the treatment of non-smallcell lung cancer
    • Brahmer JR. Harnessing the immune system for the treatment of non-smallcell lung cancer. J Clin Oncol, 2013, 31(8): 1021-1028.
    • (2013) J Clin Oncol , vol.31 , Issue.8 , pp. 1021-1028
    • Brahmer, J.R.1
  • 6
    • 33751209215 scopus 로고    scopus 로고
    • Combined chemoimmunotherapy of solid tumours: Improving vaccines?
    • Nowak AK, Lake RA, Robinson BW. Combined chemoimmunotherapy of solid tumours: improving vaccines? Adv Drug Deliv Rev, 2006, 58(8): 975-990.
    • (2006) Adv Drug Deliv Rev , vol.58 , Issue.8 , pp. 975-990
    • Nowak, A.K.1    Lake, R.A.2    Robinson, B.W.3
  • 7
    • 84874108466 scopus 로고    scopus 로고
    • Chemoimmunotherapy: Reengineering tumor immunity
    • Chen G, Emens LA. Chemoimmunotherapy: reengineering tumor immunity. Cancer Immunol Immunother, 2013, 62(2): 203-216.
    • (2013) Cancer Immunol Immunother , vol.62 , Issue.2 , pp. 203-216
    • Chen, G.1    Emens, L.A.2
  • 8
    • 84864954385 scopus 로고    scopus 로고
    • Lung cancer: A classic example of tumor escape and progression while providing opportunities for immunological intervention
    • Jadus MR, Natividad J, Mai A, et al. Lung cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention. Clin Dev Immunol, 2012, 2012: 160724.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 160724
    • Jadus, M.R.1    Natividad, J.2    Mai, A.3
  • 9
    • 84863594742 scopus 로고    scopus 로고
    • Cellular constituents of immune escape within the tumor microenvironment
    • Kerkar SP, Restifo NP. Cellular constituents of immune escape within the tumor microenvironment. Cancer Res, 2012, 72(13): 3125-3130.
    • (2012) Cancer Res , vol.72 , Issue.13 , pp. 3125-3130
    • Kerkar, S.P.1    Restifo, N.P.2
  • 10
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity, 2004, 21(2): 137-148.
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 11
    • 33846225204 scopus 로고    scopus 로고
    • MHC class I antigens and immune surveillance in transformed cells
    • Aptsiauri N, Cabrera T, Garcia-Lora A, et al. MHC class I antigens and immune surveillance in transformed cells. Int Rev Cytol, 2007, 256: 139-189.
    • (2007) Int Rev Cytol , vol.256 , pp. 139-189
    • Aptsiauri, N.1    Cabrera, T.2    Garcia-Lora, A.3
  • 12
    • 34250790785 scopus 로고    scopus 로고
    • Tumor cells prevent mouse dendritic cell maturation induced by TLR ligands
    • Idoyaga J, Moreno J, Bonifaz L. Tumor cells prevent mouse dendritic cell maturation induced by TLR ligands. Cancer Immunol Immunother, 2007, 56(8): 1237-1250.
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.8 , pp. 1237-1250
    • Idoyaga, J.1    Moreno, J.2    Bonifaz, L.3
  • 13
    • 84861731964 scopus 로고    scopus 로고
    • Vaccination therapy for non-smallcell lung cancer: Review of agents in phase III development
    • Decoster L, Wauters I, Vansteenkiste JF. Vaccination therapy for non-smallcell lung cancer: review of agents in phase III development. Ann Oncol, 2012, 23(6): 1387-1393.
    • (2012) Ann Oncol , vol.23 , Issue.6 , pp. 1387-1393
    • Decoster, L.1    Wauters, I.2    Vansteenkiste, J.F.3
  • 14
    • 28144457350 scopus 로고    scopus 로고
    • Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer
    • Gure AO, Chua R, Williamson B, et al. Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer. Clin Cancer Res, 2005, 11(22): 8055-8062.
    • (2005) Clin Cancer Res , vol.11 , Issue.22 , pp. 8055-8062
    • Gure, A.O.1    Chua, R.2    Williamson, B.3
  • 15
    • 84880755387 scopus 로고    scopus 로고
    • Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: Phase II randomized study results
    • Vansteenkiste J, Zielinski M, Linder A, et al. Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results. J Clin Oncol, 2013, 31(19): 2396-2403.
    • (2013) J Clin Oncol , vol.31 , Issue.19 , pp. 2396-2403
    • Vansteenkiste, J.1    Zielinski, M.2    Linder, A.3
  • 16
    • 34547661985 scopus 로고    scopus 로고
    • L-BLP25: A peptide vaccine strategy in non small cell lung cancer
    • Sangha R, Butts C. L-BLP25: a peptide vaccine strategy in non small cell lung cancer. Clin Cancer Res, 2007, 13(15 Pt 2): s4652-s4654.
    • (2007) Clin Cancer Res , vol.13 , Issue.15 PART 2
    • Sangha, R.1    Butts, C.2
  • 17
    • 27244449289 scopus 로고    scopus 로고
    • Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer
    • Butts C, Murray N, Maksymiuk A, et al. Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer. J Clin Oncol, 2005, 23(27): 6674-6681.
    • (2005) J Clin Oncol , vol.23 , Issue.27 , pp. 6674-6681
    • Butts, C.1    Murray, N.2    Maksymiuk, A.3
  • 18
    • 80054742888 scopus 로고    scopus 로고
    • Updated survival analysis in patients with stage IIIB or IV non-small-cell lung cancer receiving BLP25 liposome vaccine (L-BLP25): Phase IIB randomized, multicenter, open-label trial
    • Butts C, Maksymiuk A, Goss G, et al. Updated survival analysis in patients with stage IIIB or IV non-small-cell lung cancer receiving BLP25 liposome vaccine (L-BLP25): phase IIB randomized, multicenter, open-label trial. J Cancer Res Clin Oncol, 2011, 137(9): 1337-1342.
    • (2011) J Cancer Res Clin Oncol , vol.137 , Issue.9 , pp. 1337-1342
    • Butts, C.1    Maksymiuk, A.2    Goss, G.3
  • 19
    • 81255127285 scopus 로고    scopus 로고
    • Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: A controlled phase 2B trial
    • Quoix E, Ramlau R, Westeel V, et al. Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: a controlled phase 2B trial. Lancet Oncol, 2011, 12(12): 1125-1133.
    • (2011) Lancet Oncol , vol.12 , Issue.12 , pp. 1125-1133
    • Quoix, E.1    Ramlau, R.2    Westeel, V.3
  • 20
    • 84855170210 scopus 로고    scopus 로고
    • A phase I study of vaccination with NYESO-1f peptide mixed with Picibanil OK-432 and Montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen
    • Kakimi K, Isobe M, Uenaka A, et al. A phase I study of vaccination with NYESO-1f peptide mixed with Picibanil OK-432 and Montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen. Int J Cancer, 2011, 129(12): 2836-2846.
    • (2011) Int J Cancer , vol.129 , Issue.12 , pp. 2836-2846
    • Kakimi, K.1    Isobe, M.2    Uenaka, A.3
  • 21
    • 33750586798 scopus 로고    scopus 로고
    • Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense genemodified allogeneic tumor cell vaccine in non-small-cell lung cancer
    • Nemunaitis J, Dillman RO, Schwarzenberger PO, et al. Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense genemodified allogeneic tumor cell vaccine in non-small-cell lung cancer. J Clin Oncol, 2006, 24(29): 4721-4730.
    • (2006) J Clin Oncol , vol.24 , Issue.29 , pp. 4721-4730
    • Nemunaitis, J.1    Dillman, R.O.2    Schwarzenberger, P.O.3
  • 22
    • 67651091694 scopus 로고    scopus 로고
    • Phase II trial of Belagenpumatucel-L, a TGF-beta2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients
    • Nemunaitis J, Nemunaitis M, Senzer N, et al. Phase II trial of Belagenpumatucel-L, a TGF-beta2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients. Cancer Gene Ther, 2009, 16(8): 620-624.
    • (2009) Cancer Gene Ther , vol.16 , Issue.8 , pp. 620-624
    • Nemunaitis, J.1    Nemunaitis, M.2    Senzer, N.3
  • 23
    • 0031775979 scopus 로고    scopus 로고
    • A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: Report of a pilot clinical trial
    • Gonzalez G, Crombet T, Catala M, et al. A novel cancer vaccine composed of human-recombinant epidermal growth factor linked to a carrier protein: report of a pilot clinical trial. Ann Oncol, 1998, 9(4): 431-435.
    • (1998) Ann Oncol , vol.9 , Issue.4 , pp. 431-435
    • Gonzalez, G.1    Crombet, T.2    Catala, M.3
  • 24
    • 38949193901 scopus 로고    scopus 로고
    • Effective inhibition of the epidermal growth factor/epidermal growth factor receptor binding by antiepidermal growth factor antibodies is related to better survival in advanced non-small-cell lung cancer patients treated with the epidermal growth factor cancer vaccine
    • Garcia B, Neninger E, de la Torre A, et al. Effective inhibition of the epidermal growth factor/epidermal growth factor receptor binding by antiepidermal growth factor antibodies is related to better survival in advanced non-small-cell lung cancer patients treated with the epidermal growth factor cancer vaccine. Clin Cancer Res, 2008, 14(3): 840-846.
    • (2008) Clin Cancer Res , vol.14 , Issue.3 , pp. 840-846
    • Garcia, B.1    Neninger, E.2    de la Torre, A.3
  • 25
    • 41149159650 scopus 로고    scopus 로고
    • Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small-cell lung cancer
    • Neninger Vinageras E, de la Torre A, Osorio Rodriguez M, et al. Phase II randomized controlled trial of an epidermal growth factor vaccine in advanced non-small-cell lung cancer. J Clin Oncol, 2008, 26(9): 1452-1458.
    • (2008) J Clin Oncol , vol.26 , Issue.9 , pp. 1452-1458
    • Neninger Vinageras, E.1    de la Torre, A.2    Osorio Rodriguez, M.3
  • 26
    • 34447624543 scopus 로고    scopus 로고
    • Current approaches in dendritic cell generation and future implications for cancer immunotherapy
    • Tuyaerts S, Aerts JL, Corthals J, et al. Current approaches in dendritic cell generation and future implications for cancer immunotherapy. Cancer Immunol Immunother, 2007, 56(10): 1513-1537.
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.10 , pp. 1513-1537
    • Tuyaerts, S.1    Aerts, J.L.2    Corthals, J.3
  • 27
    • 77957016923 scopus 로고    scopus 로고
    • Phase I study of autologous dendritic cell tumor vaccine in patients with non-small cell lung cancer
    • Um SJ, Choi YJ, Shin HJ, et al. Phase I study of autologous dendritic cell tumor vaccine in patients with non-small cell lung cancer. Lung Cancer, 2010, 70(2): 188-194.
    • (2010) Lung Cancer , vol.70 , Issue.2 , pp. 188-194
    • Um, S.J.1    Choi, Y.J.2    Shin, H.J.3
  • 28
    • 79960858227 scopus 로고    scopus 로고
    • Chemotherapy with or without low-dose interleukin-2 in advanced non-small cell lung cancer: Results from a phase III randomized multicentric trial
    • Ridolfi L, Bertetto O, Santo A, et al. Chemotherapy with or without low-dose interleukin-2 in advanced non-small cell lung cancer: results from a phase III randomized multicentric trial. Int J Oncol, 2011, 39(4): 1011-1017.
    • (2011) Int J Oncol , vol.39 , Issue.4 , pp. 1011-1017
    • Ridolfi, L.1    Bertetto, O.2    Santo, A.3
  • 29
    • 84856577648 scopus 로고    scopus 로고
    • Neo-adjuvant chemo/immunotherapy in the treatment of stage III (N2) non-small cell lung cancer: A phase I/II pilot study
    • Ratto GB, Costa R, Maineri P, et al. Neo-adjuvant chemo/immunotherapy in the treatment of stage III (N2) non-small cell lung cancer: a phase I/II pilot study. Int J Immunopathol Pharmacol, 2011, 24(4): 1005-1016.
    • (2011) Int J Immunopathol Pharmacol , vol.24 , Issue.4 , pp. 1005-1016
    • Ratto, G.B.1    Costa, R.2    Maineri, P.3
  • 30
    • 84875013121 scopus 로고    scopus 로고
    • Current adoptive immunotherapy in non-small cell lung cancer and potential influence of therapy outcome
    • Zheng YW, Li RM, Zhang XW, et al. Current adoptive immunotherapy in non-small cell lung cancer and potential influence of therapy outcome. Cancer Invest, 2013, 31(3): 197-205.
    • (2013) Cancer Invest , vol.31 , Issue.3 , pp. 197-205
    • Zheng, Y.W.1    Li, R.M.2    Zhang, X.W.3
  • 31
    • 84892164186 scopus 로고    scopus 로고
    • A prospective study of the efficacy of a combination of autologous dendritic cells, cytokine-induced killer cells, and chemotherapy in advanced non-small cell lung cancer patients
    • [Epub ahead of print]
    • Zhong R, Han B, Zhong H. A prospective study of the efficacy of a combination of autologous dendritic cells, cytokine-induced killer cells, and chemotherapy in advanced non-small cell lung cancer patients. Tumour Biol, 2013. [Epub ahead of print].
    • (2013) Tumour Biol
    • Zhong, R.1    Han, B.2    Zhong, H.3
  • 32
    • 71149114221 scopus 로고    scopus 로고
    • Dendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patients after surgery
    • Li H, Wang C, Yu J, et al. Dendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patients after surgery. Cytotherapy, 2009, 11(8): 1076-1083.
    • (2009) Cytotherapy , vol.11 , Issue.8 , pp. 1076-1083
    • Li, H.1    Wang, C.2    Yu, J.3
  • 33
    • 33646572848 scopus 로고    scopus 로고
    • Phase I trial of oral talactoferrin alfa in refractory solid tumors
    • Hayes TG, Falchook GF, Varadhachary GR, et al. Phase I trial of oral talactoferrin alfa in refractory solid tumors. Invest New Drugs, 2006, 24(3): 233-240.
    • (2006) Invest New Drugs , vol.24 , Issue.3 , pp. 233-240
    • Hayes, T.G.1    Falchook, G.F.2    Varadhachary, G.R.3
  • 34
    • 79958111407 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, phase II study of oral talactoferrin in combination with carboplatin and paclitaxel in previously untreated locally advanced or metastatic non-small cell lung cancer
    • Digumarti R, Wang Y, Raman G, et al. A randomized, double-blind, placebo-controlled, phase II study of oral talactoferrin in combination with carboplatin and paclitaxel in previously untreated locally advanced or metastatic non-small cell lung cancer. J Thorac Oncol, 2011, 6(6): 1098-1103.
    • (2011) J Thorac Oncol , vol.6 , Issue.6 , pp. 1098-1103
    • Digumarti, R.1    Wang, Y.2    Raman, G.3
  • 35
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol EA, Borriello F, Schweitzer AN, et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity, 1995, 3(5): 541-547.
    • (1995) Immunity , vol.3 , Issue.5 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3
  • 36
    • 84863911486 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-smallcell lung cancer: Results from a randomized, double-blind, multicenter phase II study
    • Lynch TJ, Bondarenko I, Luft A, et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-smallcell lung cancer: results from a randomized, double-blind, multicenter phase II study. J Clin Oncol, 2012, 30(17): 2046-2054.
    • (2012) J Clin Oncol , vol.30 , Issue.17 , pp. 2046-2054
    • Lynch, T.J.1    Bondarenko, I.2    Luft, A.3
  • 37
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res, 2009, 15(23): 7412-7420.
    • (2009) Clin Cancer Res , vol.15 , Issue.23 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3
  • 38
    • 84871532643 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: Results from a randomized, double-blind, multicenter phase 2 trial
    • Reck M, Bondarenko I, Luft A, et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial. Ann Oncol, 2013, 24(1): 75-83.
    • (2013) Ann Oncol , vol.24 , Issue.1 , pp. 75-83
    • Reck, M.1    Bondarenko, I.2    Luft, A.3
  • 39
    • 42649125225 scopus 로고    scopus 로고
    • PD-1 and its ligands in tolerance and immunity
    • Keir ME, Butte MJ, Freeman GJ, et al. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol, 2008, 26: 677-704.
    • (2008) Annu Rev Immunol , vol.26 , pp. 677-704
    • Keir, M.E.1    Butte, M.J.2    Freeman, G.J.3
  • 40
    • 77957664158 scopus 로고    scopus 로고
    • Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer
    • Zhang Y, Huang S, Gong D, et al. Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer. Cell Mol Immunol, 2010, 7(5): 389-395.
    • (2010) Cell Mol Immunol , vol.7 , Issue.5 , pp. 389-395
    • Zhang, Y.1    Huang, S.2    Gong, D.3
  • 41
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med, 2012, 366(26): 2443-2454.
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 42
    • 57849117384 scopus 로고    scopus 로고
    • New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
    • Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer, 2009, 45(2): 228-247.
    • (2009) Eur J Cancer , vol.45 , Issue.2 , pp. 228-247
    • Eisenhauer, E.A.1    Therasse, P.2    Bogaerts, J.3
  • 43
    • 33845993628 scopus 로고    scopus 로고
    • A clinical development paradigm for cancer vaccines and related biologics
    • Hoos A, Parmiani G, Hege K, et al. A clinical development paradigm for cancer vaccines and related biologics. J Immunother, 2007, 30(1): 1-15.
    • (2007) J Immunother , vol.30 , Issue.1 , pp. 1-15
    • Hoos, A.1    Parmiani, G.2    Hege, K.3


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