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Volumn 11, Issue 12, 2013, Pages 1466-1470

Vemurafenib treatment of BRAF V600E-mutated malignant peripheral nerve sheath tumor

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; DESMIN; GLUCOCORTICOID; PROTEIN S 100; SORAFENIB; VEMURAFENIB;

EID: 84891950188     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2013.0173     Document Type: Article
Times cited : (23)

References (26)
  • 1
    • 84856994155 scopus 로고    scopus 로고
    • Oncogene mutation survey in MPNST cell lines enhances the dominant role of hyperactive Ras in NF1 associated pro-survival and malignancy
    • Sun D, Tainsky MA, Haddad R. Oncogene mutation survey in MPNST cell lines enhances the dominant role of hyperactive Ras in NF1 associated pro-survival and malignancy. Transl Oncologenomics 2012;5:1-7.
    • (2012) Transl Oncologenomics , vol.5 , pp. 1-7
    • Sun, D.1    Tainsky, M.A.2    Haddad, R.3
  • 2
    • 64549151639 scopus 로고    scopus 로고
    • Germline and somatic NF1 mutations in sporadic and NF-1 associated malignant nerve sheath tumors
    • Bottillo I, Ahlquist T, Brekke H, et al. Germline and somatic NF1 mutations in sporadic and NF-1 associated malignant nerve sheath tumors. J Pathol 2009;217:693-701.
    • (2009) J Pathol , vol.217 , pp. 693-701
    • Bottillo, I.1    Ahlquist, T.2    Brekke, H.3
  • 3
    • 84873809147 scopus 로고    scopus 로고
    • MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors
    • Jessen WJ, Miller SJ, Jousma E, et al. MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. J Clin Invest 2013;123:340-347.
    • (2013) J Clin Invest , vol.123 , pp. 340-347
    • Jessen, W.J.1    Miller, S.J.2    Jousma, E.3
  • 4
    • 42249087305 scopus 로고    scopus 로고
    • Sorafenib inhibits growth and MAPK signaling in malignant peripheral nerve sheath cells
    • Ambrosini G, Cheema HS, Seetman S, et al. Sorafenib inhibits growth and MAPK signaling in malignant peripheral nerve sheath cells. Mol Cancer Ther 2012;7:890-896.
    • (2012) Mol Cancer Ther , vol.7 , pp. 890-896
    • Ambrosini, G.1    Cheema, H.S.2    Seetman, S.3
  • 5
    • 77955602211 scopus 로고    scopus 로고
    • Gatekeeper mutations mediate resistance to BRAF-targeted therapies
    • Whittaker S, Kirk R, Hayward R, et al. Gatekeeper mutations mediate resistance to BRAF-targeted therapies. Sci Transl Med 2010;2:35ra41.
    • (2010) Sci Transl Med , vol.2
    • Whittaker, S.1    Kirk, R.2    Hayward, R.3
  • 6
    • 67650293850 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with metastatic or recurrent sarcomas
    • Maki RG, D'Adamo DR, Keohan ML, et al. Phase II study of sorafenib in patients with metastatic or recurrent sarcomas. J Clin Oncol 2009;27:3133-3140.
    • (2009) J Clin Oncol , vol.27 , pp. 3133-3140
    • Maki, R.G.1    D'Adamo, D.R.2    Keohan, M.L.3
  • 7
    • 79959293462 scopus 로고    scopus 로고
    • BRAF mutations in hairy cell leukemia
    • Tiacci E, Frifonov V, Schiavoni G, et al. BRAF mutations in hairy cell leukemia. N Engl J Med 2011;364:2305-2315.
    • (2011) N Engl J Med , vol.364 , pp. 2305-2315
    • Tiacci, E.1    Frifonov, V.2    Schiavoni, G.3
  • 8
    • 84872650338 scopus 로고    scopus 로고
    • BRAF V600E and KRAS G12S mutations in peripheral nerve sheath tumors
    • Serrano C, Simonetti S, Hernandez-Losa J, et al. BRAF V600E and KRAS G12S mutations in peripheral nerve sheath tumors. Histopathology 2013;62:499-504.
    • (2013) Histopathology , vol.62 , pp. 499-504
    • Serrano, C.1    Simonetti, S.2    Hernandez-Losa, J.3
  • 9
    • 85042692200 scopus 로고    scopus 로고
    • BRAF V600E mutations in benign and malignant nerve sheath tumors
    • [abstract]. Abstract 10043
    • Serrano C, Simonetti S, Hernandez J, et al. BRAF V600E mutations in benign and malignant nerve sheath tumors [abstract]. J Clin Oncol 2010;28(Suppl 15):Abstract 10043.
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL. 15
    • Serrano, C.1    Simonetti, S.2    Hernandez, J.3
  • 10
    • 79954441895 scopus 로고    scopus 로고
    • Analysis of BRAF v600e mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma, and extra-cerebellar pilocytic astrocytoma
    • Schindler G, Capper D, Meyer J, et al. Analysis of BRAF v600e mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma, and extra-cerebellar pilocytic astrocytoma. Acta Neuropathol 2011;121:397-405.
    • (2011) Acta Neuropathol , vol.121 , pp. 397-405
    • Schindler, G.1    Capper, D.2    Meyer, J.3
  • 11
    • 1442323605 scopus 로고    scopus 로고
    • BRAF mutations are common somatic events in melanocytic nevi
    • Kumar R, Angelini S, Snellman E, et al. BRAF mutations are common somatic events in melanocytic nevi. J Invest Dermatol 2004;122:342-348.
    • (2004) J Invest Dermatol , vol.122 , pp. 342-348
    • Kumar, R.1    Angelini, S.2    Snellman, E.3
  • 12
    • 78649723255 scopus 로고    scopus 로고
    • PLX4032 in metastatic colorectal cancer patients with mutant BRAF tumors
    • [abstract]. Abstract 3534
    • Kopetz S, Desai J, Chan E, et al. PLX4032 in metastatic colorectal cancer patients with mutant BRAF tumors [abstract]. J Clin Oncol 2010;28(15 Suppl):Abstract 3534.
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL.
    • Kopetz, S.1    Desai, J.2    Chan, E.3
  • 13
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman PB, Hauschild HA, Haanen RC, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011;364:2507-2516.
    • (2011) N Engl J Med , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, H.A.2    Haanen, R.C.3
  • 14
    • 84877600792 scopus 로고    scopus 로고
    • Déjà vu: EGF receptors drive resistance to BRAF inhibitors
    • Girotti M, Marais R. Déjà vu: EGF receptors drive resistance to BRAF inhibitors. Cancer Discov 2013;3:487-590.
    • (2013) Cancer Discov , vol.3 , pp. 487-590
    • Girotti, M.1    Marais, R.2
  • 15
    • 48249114422 scopus 로고    scopus 로고
    • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer
    • Koivunen JP, Mermel C, Zejnullah K, et al. EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. Clin Cancer Res 2008;14:4275-4283.
    • (2008) Clin Cancer Res , vol.14 , pp. 4275-4283
    • Koivunen, J.P.1    Mermel, C.2    Zejnullah, K.3
  • 16
    • 78650303507 scopus 로고    scopus 로고
    • Melanomas acquire resistance to B-RAF (V600E) inhibition by RTK or N-RAS upregulation
    • Nazarian R, Shi H, Wang Q, et al. Melanomas acquire resistance to B-RAF (V600E) inhibition by RTK or N-RAS upregulation. Nature 2010;468:973-977.
    • (2010) Nature , vol.468 , pp. 973-977
    • Nazarian, R.1    Shi, H.2    Wang, Q.3
  • 17
    • 84879496934 scopus 로고    scopus 로고
    • Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma
    • Trunzer K, Pavlick AC, Schuchter L, et al. Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma. J Clin Oncol 2013;31:1767-1774.
    • (2013) J Clin Oncol , vol.31 , pp. 1767-1774
    • Trunzer, K.1    Pavlick, A.C.2    Schuchter, L.3
  • 18
    • 84868224906 scopus 로고    scopus 로고
    • Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
    • Flaherty KT, Jeffrey R, Infante JR, et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med 2012;367:1694-1703.
    • (2012) N Engl J Med , vol.367 , pp. 1694-1703
    • Flaherty, K.T.1    Jeffrey, R.2    Infante, J.R.3
  • 19
    • 84863230465 scopus 로고    scopus 로고
    • Unresponsiveness of colon cancer to BRAF (V600E) inhibition through feedback activation of EGFR
    • Prahallad A, Sun C, Huang S, et al. Unresponsiveness of colon cancer to BRAF (V600E) inhibition through feedback activation of EGFR. Nature 2012;483:101-104.
    • (2012) Nature , vol.483 , pp. 101-104
    • Prahallad, A.1    Sun, C.2    Huang, S.3
  • 20
    • 84873360893 scopus 로고    scopus 로고
    • Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents
    • Mao M, Tian F, Mariadason JM, et al. Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents. Clin Cancer Res 2013;19:657-667.
    • (2013) Clin Cancer Res , vol.19 , pp. 657-667
    • Mao, M.1    Tian, F.2    Mariadason, J.M.3
  • 21
    • 84877631604 scopus 로고    scopus 로고
    • Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas
    • Montero-Conde C, Ruiz-Llorente S, Dominguez JM, et al. Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas. Cancer Discov 2013;3:520-533.
    • (2013) Cancer Discov , vol.3 , pp. 520-533
    • Montero-Conde, C.1    Ruiz-Llorente, S.2    Dominguez, J.M.3
  • 22
    • 0034102193 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models
    • DeClue JE, Heffelfinger S, Benvenuto G, et al. Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models. J Clin Invest 2000;105:1233-1241.
    • (2000) J Clin Invest , vol.105 , pp. 1233-1241
    • DeClue, J.E.1    Heffelfinger, S.2    Benvenuto, G.3
  • 23
    • 66849131261 scopus 로고    scopus 로고
    • Dual targeting of AKT and mammalian target of rapamycin: A potential therapeutic approach for malignant peripheral nerve sheath tumor
    • Zou CY, Smith KD, Zhu QS, et al. Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor. Mol Cancer Ther 2009;8:1157-1168.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1157-1168
    • Zou, C.Y.1    Smith, K.D.2    Zhu, Q.S.3
  • 24
    • 84864285936 scopus 로고    scopus 로고
    • BRAF inhibition and beyond in advanced melanoma
    • Margolin K. BRAF inhibition and beyond in advanced melanoma. Lancet 2012;380:320-322.
    • (2012) Lancet , vol.380 , pp. 320-322
    • Margolin, K.1
  • 25
    • 83455254767 scopus 로고    scopus 로고
    • RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E)
    • Poulikakos PI, Persaud Y, Janakiraman MJ, et al. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E). Nature 2011;480:387-390.
    • (2011) Nature , vol.480 , pp. 387-390
    • Poulikakos, P.I.1    Persaud, Y.2    Janakiraman, M.J.3
  • 26
    • 77954218212 scopus 로고    scopus 로고
    • BRAF as therapeutic target in melanoma
    • Wellbrock C, Hurlstone A. BRAF as therapeutic target in melanoma. Biochem Pharmacol 2010;80:561-567.
    • (2010) Biochem Pharmacol , vol.80 , pp. 561-567
    • Wellbrock, C.1    Hurlstone, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.