Investigation of the l-phenylacetylcarbinol process to substituted benzaldehydes of interest

Forensic Science International

Volumn 235, Issue , 2014, Pages 52-61

  Maroney, Kerrie Anne N ^a,b   Culshaw, Peter N ^a   Wermuth, Urs D ^a,b   Cresswell, Sarah L ^b  

^a QUEENSLAND HEALTH   (Australia)

^b GRIFFITH UNIVERSITY   (Australia)

Author keywords

Biotransformation; Clandestine; Ephedrine; L PAC; Methamphetamine

Indexed keywords

BENZALDEHYDE DERIVATIVE; EPHEDRINE DERIVATIVE; LEVO PHENYLACETYLCARBINOL; METHAMPHETAMINE; METHANOL DERIVATIVE; METHCATHINONE; PSEUDOEPHEDRINE; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; FERMENTATION TECHNIQUE; MASS FRAGMENTOGRAPHY; NUCLEAR MAGNETIC RESONANCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SYNTHESIS;

EID: 84891939942     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2013.11.017     Document Type: Article

References (12)

1. Neuberg C., Hirsch J. An enzyme which brings about union into carbon chains (Carboligase). Biochemische Zeitschrift 1921, 115:282-310.
2. Neuberg C., Liebermann L. Carboligase II. Biochemische Zeitschrift 1921, 121:311-325.
3. Cox M., Klass G., Koo C. Forensic aspects of the biotransformation of benzaldehyde used in the synthesis of methamphetamine, part 1: reaction conditions, stereochemical outcomes, and the use of other substituted benzaldehydes. Journal of the Clandestine Laboratory Investigating Chemists Association 2009, 19(4):20-37.
4. Shukla V., Kulkarni P. l-Phenylacetylcarbinol (l-PAC): biosynthesis and industrial applications. World Journal of Microbiology and Biotechnology 2000, 16(6):499-506.
5. Neuberg C., Ohle H., Carboligase I.V. Biosynthetic carbon chain union in fermentation process. Biochemische Zeitschrift 1922, 128:610-618.
6. Szendrei K. The chemistry of khat. Bullentin on Narcotics 1980, XXXII(3.).
7. Shin H., Rogers P. Production of l-phenylacetylcarbinol (l-PAC) from benzaldehyde using partially purified pyruvate decarboxylase (PDC). Biotechnology and Bioengineering 1996, 49(1):52-62.
8. Overman L. Organic Reactions 2002, vol 59. John Wiley & Sons, Inc., Hoboken, NJ.
9. SWGDRUG, 4-Fluoromethamphetamine. Scientific Working Group for the Analysis of Seized Drugs: 2013.
10. SWGDRUG, 4-Methylmethcathinone. Scientific Working Group for the Analysis of Seized Drugs: 2013.
11. SWGDRUG, 4-Fluoromethcathinone. Scientific Working Group for the Analysis of Seized Drugs: 2013.
12. UNODC Amphetamines and Ecstasy: 2011 Global ATS Assessment 2011, United Nations Office on Drugs and Crime, United Nations Publication, Sales No. E.11.XI.13.