Protein structural ensembles are revealed by redefining X-ray electron density noise

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 1, 2014, Pages 237-242

  Lang, P Therese ^a   Holton, James M ^b,c   Fraser, James S ^a,d   Alber, Tom ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Electron number density; Molecular motions; Protein dynamics; Refinement against perturbed input data; Ringer

Indexed keywords

ALANINE; CAPSID PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; HYDROGEN; NUCLEOTIDE;

ALLOSTERISM; ARTICLE; BINDING SITE; CHEMICAL PARAMETERS; CONTROLLED STUDY; ELECTRON DENSITY; NOISE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ELECTRON NUMBER DENSITY; MOLECULAR MOTIONS; PROTEIN DYNAMICS; REFINEMENT AGAINST PERTURBED INPUT DATA; RINGER;

ALLOSTERIC SITE; ANISOTROPY; BACTERIOPHAGE T4; CASEIN KINASE II; CATALYTIC DOMAIN; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 2; DEATH-ASSOCIATED PROTEIN KINASES; ELECTRONS; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INTERLEUKIN-1BETA; MOTION; MURAMIDASE; PROTEIN CONFORMATION; PROTEIN KINASES; PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; REPRODUCIBILITY OF RESULTS; SCORPION VENOMS;

EID: 84891915215     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302823110     Document Type: Article

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