-
1
-
-
70049112901
-
Guidelines for the diagnosis and treatment of pulmonary hypertension
-
19713419 10.1093/eurheartj/ehp297
-
Galie N, Hoeper MM, Humbert M et al (2009) Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J 30:2493-2537
-
(2009)
Eur Heart J
, vol.30
, pp. 2493-2537
-
-
Galie, N.1
Hoeper, M.M.2
Humbert, M.3
-
2
-
-
84863519076
-
An evaluation of long-term survival from time of diagnosis in pulmonary arterial hypertension from the REVEAL Registry
-
22281797 10.1378/chest.11-1460
-
Benza RL, Miller DP, Barst RJ et al (2012) An evaluation of long-term survival from time of diagnosis in pulmonary arterial hypertension from the REVEAL Registry. Chest 142:448-456
-
(2012)
Chest
, vol.142
, pp. 448-456
-
-
Benza, R.L.1
Miller, D.P.2
Barst, R.J.3
-
4
-
-
0026628265
-
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension
-
1:STN:280:DyaK383ptlaksA%3D%3D 10.1056/NEJM199207093270202
-
Christman BW, McPherson CD, Newman JH et al (1992) An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. N Eng J Med 327:70-75
-
(1992)
N Eng J Med
, vol.327
, pp. 70-75
-
-
Christman, B.W.1
McPherson, C.D.2
Newman, J.H.3
-
5
-
-
0021367046
-
Long-term treatment of primary pulmonary hypertension with continuous intravenous epoprostenol (prostacyclin)
-
Higenbottam T, Wheeldon D, Wells F et al (1984) Long-term treatment of primary pulmonary hypertension with continuous intravenous epoprostenol (prostacyclin). Lancet 1:1046-1047 (Pubitemid 14148935)
-
(1984)
Lancet
, vol.1
, Issue.8385
, pp. 1046-1047
-
-
Higenbottam, T.1
Wheeldon, D.2
Wells, F.3
Wallwork, J.4
-
6
-
-
42949166212
-
Prostacyclin therapies for the treatment of pulmonary arterial hypertension
-
1:CAS:528:DC%2BD1cXlsFyjsL0%3D 18378784 10.1183/09031936.00097107
-
Gomberg-Maitland M, Olschewski H (2008) Prostacyclin therapies for the treatment of pulmonary arterial hypertension. Eur Respir J 31:891-901
-
(2008)
Eur Respir J
, vol.31
, pp. 891-901
-
-
Gomberg-Maitland, M.1
Olschewski, H.2
-
7
-
-
84873566367
-
Efficacy and safety of oral treprostinil monotherapy for the treatment of pulmonary arterial hypertension: A randomized, controlled trial
-
1:CAS:528:DC%2BC3sXit1aqtb4%3D 23307827 10.1161/CIRCULATIONAHA.112.124388
-
Jing ZC, Parikh K, Pulido T et al (2013) Efficacy and safety of oral treprostinil monotherapy for the treatment of pulmonary arterial hypertension: A randomized, controlled trial. Circulation 127:624-633
-
(2013)
Circulation
, vol.127
, pp. 624-633
-
-
Jing, Z.C.1
Parikh, K.2
Pulido, T.3
-
8
-
-
84866515810
-
Oral treprostinil for the treatment of pulmonary arterial hypertension in patients on background endothelin receptor antagonist and/or phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C study): A randomized controlled trial
-
1:CAS:528:DC%2BC3sXkvFWltw%3D%3D 22628490 10.1378/chest.11-2212
-
Tapson VF, Torres F, Kermeen F et al (2012) Oral treprostinil for the treatment of pulmonary arterial hypertension in patients on background endothelin receptor antagonist and/or phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C study): A randomized controlled trial. Chest 142:1383-1390
-
(2012)
Chest
, vol.142
, pp. 1383-1390
-
-
Tapson, V.F.1
Torres, F.2
Kermeen, F.3
-
9
-
-
84863984607
-
Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials
-
1:CAS:528:DC%2BC38XhtVCrsrbN 22696079 10.1161/CIRCULATIONAHA.112.105890
-
Gabler NB, French B, Strom BL et al (2012) Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials. Circulation 126:349-356
-
(2012)
Circulation
, vol.126
, pp. 349-356
-
-
Gabler, N.B.1
French, B.2
Strom, B.L.3
-
10
-
-
84866362803
-
Do changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension? A meta-analysis of 22 randomized trials
-
22995024 10.1016/j.jacc.2012.01.083
-
Savarese G, Paolillo S, Costanzo P et al (2012) Do changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension? A meta-analysis of 22 randomized trials. J Am Coll Cardiol 60:1192-1201
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 1192-1201
-
-
Savarese, G.1
Paolillo, S.2
Costanzo, P.3
-
11
-
-
0030031888
-
A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
-
DOI 10.1056/NEJM199602013340504
-
Barst RJ, Rubin LJ, Long WA et al (1996) A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Eng J Med 334:296-301 (Pubitemid 26033085)
-
(1996)
New England Journal of Medicine
, vol.334
, Issue.5
, pp. 296-301
-
-
Barst, R.J.1
Rubin, L.J.2
Long, W.A.3
McGoon, M.D.4
Rich, S.5
Badesch, D.B.6
Groves, B.M.7
Tapson, V.F.8
Bourge, R.C.9
Brundage, B.H.10
Koerner, S.K.11
Langleben, D.12
Keller, C.A.13
Murali, S.14
Uretsky, B.F.15
Clayton, L.M.16
Jobsis, M.M.17
Blackburn Jr., S.D.18
-
12
-
-
62749192201
-
A meta-analysis of randomized controlled trials in pulmonary arterial hypertension
-
19155250 10.1093/eurheartj/ehp022
-
Galie N, Manes A, Negro L et al (2009) A meta-analysis of randomized controlled trials in pulmonary arterial hypertension. Eur Heart J 30:394-403
-
(2009)
Eur Heart J
, vol.30
, pp. 394-403
-
-
Galie, N.1
Manes, A.2
Negro, L.3
-
13
-
-
34249302372
-
A meta-analysis of trials of pulmonary hypertension: A clinical condition looking for drugs and research methodology
-
DOI 10.1016/j.ahj.2007.02.037, PII S0002870307001731
-
Macchia A, Marchioli R, Marfisi R et al (2007) A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology. Am Heart J 153:1037-1047 (Pubitemid 46809838)
-
(2007)
American Heart Journal
, vol.153
, Issue.6
, pp. 1037-1047
-
-
Macchia, A.1
Marchioli, R.2
Marfisi, R.3
Scarano, M.4
Levantesi, G.5
Tavazzi, L.6
Tognoni, G.7
-
14
-
-
77952506822
-
Pharmacotherapy in pulmonary arterial hypertension: A systematic review and meta-analysis
-
2835653 20113497 10.1186/1465-9921-11-12
-
Ryerson CJ, Nayar S, Swiston JR et al (2010) Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis. Respir Res 11:12
-
(2010)
Respir Res
, vol.11
, pp. 12
-
-
Ryerson, C.J.1
Nayar, S.2
Swiston, J.R.3
-
15
-
-
84880470790
-
Prostacyclin and its analogues in pulmonary artery hypertension: A meta-analysis
-
23647397 10.1185/03007995.2013.802682
-
Li T, Chen Y, Zang W et al (2013) Prostacyclin and its analogues in pulmonary artery hypertension: a meta-analysis. Curr Med Res Opin 29:889-999
-
(2013)
Curr Med Res Opin
, vol.29
, pp. 889-999
-
-
Li, T.1
Chen, Y.2
Zang, W.3
-
16
-
-
74849116556
-
Exercise improvement and plasma biomarker changes with intravenous treprostinil therapy for pulmonary arterial hypertension: A placebo-controlled trial
-
10.1016/j.healun.2009.09.005
-
Hiremath J, Thanikachalam S, Parikh K et al (2010) Exercise improvement and plasma biomarker changes with intravenous treprostinil therapy for pulmonary arterial hypertension: a placebo-controlled trial. J Heart Lung transpl 29:137-149
-
(2010)
J Heart Lung Transpl
, vol.29
, pp. 137-149
-
-
Hiremath, J.1
Thanikachalam, S.2
Parikh, K.3
-
17
-
-
77952301237
-
Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: A randomized controlled clinical trial
-
1:CAS:528:DC%2BC3cXns1GisLc%3D 20430262 10.1016/j.jacc.2010.01.027
-
McLaughlin VV, Benza RL, Rubin LJ et al (2010) Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial. J Am Coll Cardiol 55:1915-1922
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 1915-1922
-
-
McLaughlin, V.V.1
Benza, R.L.2
Rubin, L.J.3
-
18
-
-
33845526777
-
Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
-
DOI 10.1164/rccm.200603-358OC
-
McLaughlin VV, Oudiz RJ, Frost A et al (2006) Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am J Respir Crit Care Med 174:1257-1263 (Pubitemid 44924827)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.174
, Issue.11
, pp. 1257-1263
-
-
McLaughlin, V.V.1
Oudiz, R.J.2
Frost, A.3
Tapson, V.F.4
Murali, S.5
Channick, R.N.6
Badesch, D.B.7
Barst, R.J.8
Hsu, H.H.9
Rubin, L.J.10
-
19
-
-
33847368988
-
Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension
-
DOI 10.1183/09031936.06.00057906
-
Hoeper MM, Leuchte H, Halank M et al (2006) Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension. Eur Respir J 28:691-694 (Pubitemid 46331988)
-
(2006)
European Respiratory Journal
, vol.28
, Issue.4
, pp. 691-694
-
-
Hoeper, M.M.1
Leuchte, H.2
Halank, M.3
Wilkens, H.4
Meyer, F.J.5
Seyfarth, H.J.6
Wensel, R.7
Ripken, F.8
Bremer, H.9
Kluge, S.10
Hoeffken, G.11
Behr, J.12
-
20
-
-
12244251412
-
Efficacy and safety of treprostinil: An epoprostenol analog for primary pulmonary hypertension
-
DOI 10.1097/00005344-200302000-00019
-
McLaughlin VV, Gaine SP, Barst RJ et al (2003) Efficacy and safety of treprostinil: an epoprostenol analog for primary pulmonary hypertension. J Cardiovasc Pharmacol 41:293-299 (Pubitemid 36135255)
-
(2003)
Journal of Cardiovascular Pharmacology
, vol.41
, Issue.2
, pp. 293-299
-
-
McLaughlin, V.V.1
Gaine, S.P.2
Barst, R.J.3
Oudiz, R.J.4
Bourge, R.C.5
Frost, A.6
Robbins, I.M.7
Tapson, V.F.8
McGoon, M.D.9
Badesch, D.B.10
Sigman, J.11
Roscigno, R.12
Blackburn, S.D.13
Arneson, C.14
Rubin, L.J.15
Rich, S.16
-
21
-
-
0038037766
-
Beraprost therapy for pulmonary arterial hypertension
-
DOI 10.1016/S0735-1097(03)00463-7
-
Barst RJ, McGoon M, McLaughlin V et al (2003) Beraprost therapy for pulmonary arterial hypertension. J Am Coll Cardiol 41:2119-2125 (Pubitemid 36724255)
-
(2003)
Journal of the American College of Cardiology
, vol.41
, Issue.12
, pp. 2119-2125
-
-
Barst, R.J.1
McGoon, M.2
McLaughlin, V.3
Tapson, V.4
Oudiz, R.5
Shapiro, S.6
Robbins, I.M.7
Channick, R.8
Badesch, D.9
Rayburn, B.K.10
Flinchbaugh, R.11
Sigman, J.12
Arneson, C.13
Jeffs, R.14
-
22
-
-
0037086133
-
Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: A double-blind, randomized, placebo-controlled trial
-
Simonneau G, Barst RJ, Galie N et al (2002) Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. Am J Resp Crit Care Med 165:800-804 (Pubitemid 34229650)
-
(2002)
American Journal of Respiratory and Critical Care Medicine
, vol.165
, Issue.6
, pp. 800-804
-
-
Simonneau, G.1
Barst, R.J.2
Galie, N.3
Naeije, R.4
Rich, S.5
Bourge, R.C.6
Keogh, A.7
Oudiz, R.8
Frost, A.9
Blackburn, S.D.10
Crow, J.W.11
Rubin, L.J.12
-
23
-
-
0036682273
-
Inhaled iloprost for severe pulmonary hypertension
-
DOI 10.1056/NEJMoa020204
-
Olschewski H, Simonneau G, Galie N et al (2002) Inhaled iloprost for severe pulmonary hypertension. N Eng J Med 347:322-329 (Pubitemid 34815354)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.5
, pp. 322-329
-
-
Olschewski, H.1
Simonneau, G.2
Galie, N.3
Higenbottam, T.4
Naeije, R.5
Rubin, L.J.6
Nikkho, S.7
Speich, R.8
Hoeper, M.M.9
Behr, J.10
Winkler, J.11
Sitbon, O.12
Popov, W.13
Ardeschir Ghofrani, H.14
Manes, A.15
Kiely, D.G.16
Ewert, R.17
Meyer, A.18
Corris, P.A.19
Delcroix, M.20
Gomez-Sanchez, M.21
Siedentop, H.22
Seeger, W.23
more..
-
24
-
-
0036569119
-
Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomized, double-blind, placebo-controlled trial
-
DOI 10.1016/S0735-1097(02)01786-2, PII S0735109702017862
-
Galie N, Humbert M, Vachiery JL et al (2002) Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol 39:1496-1502 (Pubitemid 34439066)
-
(2002)
Journal of the American College of Cardiology
, vol.39
, Issue.9
, pp. 1496-1502
-
-
Galie, N.1
Humbert, M.2
Vachiery, J.-L.3
Vizza, C.4
Kneussl, M.5
Manes, A.6
Sitbon, O.7
Torbicki, A.8
Delcroix, M.9
Naeije, R.10
Hoeper, M.11
Chaouat, A.12
Morand, S.13
Besse, B.14
Simonneau, G.15
-
25
-
-
17144452827
-
Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease: A randomized, controlled trial
-
Badesch DB, Tapson VF, McGoon MD et al (2000) Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Ann Intern Med 132:425-434 (Pubitemid 30149039)
-
(2000)
Annals of Internal Medicine
, vol.132
, Issue.6
, pp. 425-434
-
-
Badesch, D.B.1
Tapson, V.F.2
McGoon, M.D.3
Brundage, B.H.4
Rubin, L.J.5
Wigley, F.M.6
Rich, S.7
Barst, R.J.8
Barrett, P.S.9
Kral, K.M.10
Jobsis, M.M.11
Loyd, J.E.12
Murali, S.13
Frost, A.14
Girgis, R.15
Bourge, R.C.16
Ralph, D.D.17
Elliott, C.G.18
Hill, N.S.19
Langleben, D.20
Schilz, R.J.21
McLaughlin, V.V.22
Robbins, I.M.23
Groves, B.M.24
Shapiro, S.25
Medsger Jr., T.A.26
Gaine, S.P.27
Horn, E.28
Decker, J.C.29
Knobil, K.30
more..
-
26
-
-
0025356811
-
Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial
-
Rubin LJ, Mendoza J, Hood M et al (1990) Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial. Ann Intern Med 112:485-491 (Pubitemid 20100285)
-
(1990)
Annals of Internal Medicine
, vol.112
, Issue.7
, pp. 485-491
-
-
Rubin, L.J.1
Mendoza, J.2
Hood, M.3
McGoon, M.4
Barst, R.5
Williams, W.B.6
Diehl, J.H.7
Crow, J.8
Long, W.9
-
27
-
-
67649579669
-
Updated clinical classification of pulmonary hypertension
-
19555858 10.1016/j.jacc.2009.04.012
-
Simonneau G, Robbins IM, Beghetti M et al (2009) Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 54:S43-54
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 43-54
-
-
Simonneau, G.1
Robbins, I.M.2
Beghetti, M.3
-
28
-
-
0029914622
-
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
-
DOI 10.1016/0197-2456(95)00134-4
-
Jadad AR, Moore RA, Carroll D et al (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17:1-12 (Pubitemid 26120810)
-
(1996)
Controlled Clinical Trials
, vol.17
, Issue.1
, pp. 1-12
-
-
Jadad, A.R.1
Moore, R.A.2
Carroll, D.3
Jenkinson, C.4
Reynolds, D.J.M.5
Gavaghan, D.J.6
McQuay, H.J.7
-
29
-
-
0023484789
-
Quantitative methods in the review of epidemiologic literature
-
1:STN:280:DyaL1c%2FlsFCgtg%3D%3D 3678409
-
Greenland S (1987) Quantitative methods in the review of epidemiologic literature. Epidemiol Rev 9:1-30
-
(1987)
Epidemiol Rev
, vol.9
, pp. 1-30
-
-
Greenland, S.1
-
30
-
-
55749083074
-
Clinical benefit of steroid use in patients undergoing cardiopulmonary bypass: A meta-analysis of randomized trials
-
18664462 10.1093/eurheartj/ehn333
-
Whitlock RP, Chan S, Devereaux PJ et al (2008) Clinical benefit of steroid use in patients undergoing cardiopulmonary bypass: a meta-analysis of randomized trials. Eur Heart J 29:2592-2600
-
(2008)
Eur Heart J
, vol.29
, pp. 2592-2600
-
-
Whitlock, R.P.1
Chan, S.2
Devereaux, P.J.3
-
31
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
Egger M, Davey Smith G, Schneider M et al (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629-634 (Pubitemid 27387172)
-
(1997)
British Medical Journal
, vol.315
, Issue.7109
, pp. 629-634
-
-
Egger, M.1
Smith, G.D.2
Schneider, M.3
Minder, C.4
-
32
-
-
35448992075
-
Transition from IV epoprostenol to subcutaneous treprostinil in pulmonary arterial hypertension: A controlled trial
-
1:CAS:528:DC%2BD2sXht1amt7jF 17400684 10.1378/chest.06-2118
-
Rubenfire M, McLaughlin VV, Allen RP et al (2007) Transition from IV epoprostenol to subcutaneous treprostinil in pulmonary arterial hypertension: a controlled trial. Chest 132:757-763
-
(2007)
Chest
, vol.132
, pp. 757-763
-
-
Rubenfire, M.1
McLaughlin, V.V.2
Allen, R.P.3
-
33
-
-
77954464376
-
Meta-analysis of randomized controlled trials on treatment of pulmonary arterial hypertension
-
20519876 10.1253/circj.CJ-09-0971
-
He B, Zhang F, Li X et al (2010) Meta-analysis of randomized controlled trials on treatment of pulmonary arterial hypertension. Circ J 74:1458-1464
-
(2010)
Circ J
, vol.74
, pp. 1458-1464
-
-
He, B.1
Zhang, F.2
Li, X.3
-
34
-
-
33845360014
-
Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil
-
DOI 10.1183/09031936.06.00044406
-
Barst RJ, Galie N, Naeije R et al (2006) Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil. Eur Respir J 28:1195-1203 (Pubitemid 44883856)
-
(2006)
European Respiratory Journal
, vol.28
, Issue.6
, pp. 1195-1203
-
-
Barst, R.J.1
Galie, N.2
Naeije, R.3
Simonneau, G.4
Jeffs, R.5
Arneson, C.6
Rubin, L.J.7
-
35
-
-
0037151645
-
Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: Prognostic factors and survival
-
DOI 10.1016/S0735-1097(02)02012-0, PII S0735109702020120
-
Sitbon O, Humbert M, Nunes H et al (2002) Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. J Am Coll Cardiol 40:780-788 (Pubitemid 34925627)
-
(2002)
Journal of the American College of Cardiology
, vol.40
, Issue.4
, pp. 780-788
-
-
Sitbon, O.1
Humbert, M.2
Nunes, H.3
Parent, F.4
Garcia, G.5
Herve, P.6
Rainisio, M.7
Simonneau, G.8
-
36
-
-
84855178353
-
Combination therapy in pulmonary arterial hypertension: A meta-analysis
-
1:CAS:528:DC%2BC38XhvFags7Y%3D 22212696 10.1159/000334431
-
Bai Y, Sun L, Hu S et al (2011) Combination therapy in pulmonary arterial hypertension: a meta-analysis. Cardiology 120:157-165
-
(2011)
Cardiology
, vol.120
, pp. 157-165
-
-
Bai, Y.1
Sun, L.2
Hu, S.3
-
37
-
-
77951075510
-
Clinical worsening in trials of pulmonary arterial hypertension: Results and implications
-
20375660 10.1097/01.mcp.0000370206.61003.7e
-
Galie N, Simonneau G, Barst RJ et al (2010) Clinical worsening in trials of pulmonary arterial hypertension: results and implications. Curr Opin Pulm Med 16[Suppl 1]:S11-19
-
(2010)
Curr Opin Pulm Med
, vol.16
, Issue.SUPPL. 1
, pp. 11-19
-
-
Galie, N.1
Simonneau, G.2
Barst, R.J.3
|