메뉴 건너뛰기




Volumn 29, Issue 1, 2014, Pages 43-50

Fecal calprotectin, MMP-9, and human beta-defensin-2 levels in pediatric inflammatory bowel disease

Author keywords

Children; Colitis ulcerative; Crohn's disease; Fecal markers

Indexed keywords

BETA DEFENSIN 2; CALGRANULIN; GELATINASE B; HUMAN BETA DEFENSIN 2; UNCLASSIFIED DRUG;

EID: 84891883478     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-013-1775-9     Document Type: Article
Times cited : (44)

References (33)
  • 1
    • 33747397951 scopus 로고    scopus 로고
    • Incidence of inflammatory bowel disease in Finnish children, 1987-2003
    • DOI 10.1097/00054725-200608000-00002, PII 0005472520060800000002
    • Turunen P, Kolho KL, Auvinen A, Iltanen S, Huhtala H, Ashorn M (2006) Incidence of inflammatory bowel disease in Finnish children, 1987-2003. Inflamm Bowel Dis 12:677-683 (Pubitemid 44253750)
    • (2006) Inflammatory Bowel Diseases , vol.12 , Issue.8 , pp. 677-683
    • Turunen, P.1    Kolho, K.-L.2    Auvinen, A.3    Iltanen, S.4    Huhtala, H.5    Ashorn, M.6
  • 2
    • 34147209958 scopus 로고    scopus 로고
    • Mucosal healing in inflammatory bowel disease: Impossible ideal or therapeutic target?
    • DOI 10.1136/gut.2005.088732
    • Rutgeerts P, Vermeire S, Van Assche G (2007) Mucosal healing in inflammatory bowel disease: impossible ideal or therapeutic target? Gut 56:453-455 (Pubitemid 46580492)
    • (2007) Gut , vol.56 , Issue.4 , pp. 453-455
    • Rutgeerts, P.1    Vermeire, S.2    Van Assche, G.3
  • 3
    • 38849204268 scopus 로고    scopus 로고
    • Crohn's disease activity assessed by fecal calprotectin and lactoferrin: Correlation with Crohn's disease activity index and endoscopic findings
    • DOI 10.1002/ibd.20312
    • Sipponen T, Savilahti E, Kolho KL, Nuutinen H, Turunen U, Farkkila M (2008) Crohn's disease activity assessed by fecal calprotectin and lactoferrin: correlation with Crohn's disease activity index and endoscopic findings. Inflamm Bowel Dis 14:40-46 (Pubitemid 351196867)
    • (2008) Inflammatory Bowel Diseases , vol.14 , Issue.1 , pp. 40-46
    • Sipponen, T.1    Savilahti, E.2    Kolho, K.-L.3    Nuutinen, H.4    Turunen, U.5    Farkkila, M.6
  • 5
    • 33745262396 scopus 로고    scopus 로고
    • Role of fecal calprotectin as a biomarker of intestinal inflammation in inflammatory bowel disease
    • 16775498 10.1097/00054725-200606000-00013
    • Konikoff MR, Denson LA (2006) Role of fecal calprotectin as a biomarker of intestinal inflammation in inflammatory bowel disease. Inflamm Bowel Dis 12:524-534
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 524-534
    • Konikoff, M.R.1    Denson, L.A.2
  • 7
    • 69849103201 scopus 로고    scopus 로고
    • Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease after immunosuppressive treatment correlate with histological score and calprotectin values
    • 19652986 10.1007/s00384-009-0756-5
    • Makitalo L, Sipponen T, Kärkkäinen P, Kolho KL, Saarialho-Kere U (2009) Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease after immunosuppressive treatment correlate with histological score and calprotectin values. Int J Colorectal Dis 24:1157-1167
    • (2009) Int J Colorectal Dis , vol.24 , pp. 1157-1167
    • Makitalo, L.1    Sipponen, T.2    Kärkkäinen, P.3    Kolho, K.L.4    Saarialho-Kere, U.5
  • 8
    • 84862205870 scopus 로고    scopus 로고
    • Serum MMPs 7-9 and their inhibitors during glucocorticoid and anti-TNF-therapy in pediatric inflammatory bowel disease
    • 22519363 10.3109/00365521.2012.677954
    • Makitalo L, Rintamaki H, Tervahartiala T, Sorsa T, Kolho KL (2012) Serum MMPs 7-9 and their inhibitors during glucocorticoid and anti-TNF-therapy in pediatric inflammatory bowel disease. Scand J Gastroenterol 47:785-794
    • (2012) Scand J Gastroenterol , vol.47 , pp. 785-794
    • Makitalo, L.1    Rintamaki, H.2    Tervahartiala, T.3    Sorsa, T.4    Kolho, K.L.5
  • 9
    • 84876415302 scopus 로고    scopus 로고
    • Fecal MMP-9: A new noninvasive differential diagnostic and activity marker in ulcerative colitis
    • 10.1002/ibd.22996 22550024 10.1002/ibd.22996
    • Annahazi A, Molnar T, Farkas K, Rosztóczy A, Izbéki F, Gecse K, et al. (2013) Fecal MMP-9: a new noninvasive differential diagnostic and activity marker in ulcerative colitis. Inflamm Bowel Dis 19:316-320. doi: 10.1002/ibd.22996
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 316-320
    • Annahazi, A.1    Molnar, T.2    Farkas, K.3    Rosztóczy, A.4    Izbéki, F.5    Gecse, K.6
  • 10
    • 59749092589 scopus 로고    scopus 로고
    • Elevated human β-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome
    • 1:CAS:528:DC%2BD1MXhsFersrc%3D 19174795 10.1038/ajg.2008.86
    • Langhorst J, Junge A, Rueffer A, Wehkamp J, Foell D, Michaelsen A, Musial F, Dobos GJ (2009) Elevated human β-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome. Am J Gastroenterol 104:404-410
    • (2009) Am J Gastroenterol , vol.104 , pp. 404-410
    • Langhorst, J.1    Junge, A.2    Rueffer, A.3    Wehkamp, J.4    Foell, D.5    Michaelsen, A.6    Musial, F.7    Dobos, G.J.8
  • 11
    • 0033569408 scopus 로고    scopus 로고
    • Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6
    • 1:CAS:528:DyaK1MXmvVOhurc%3D 10521347 10.1126/science.286.5439.525
    • Yang D, Chertov O, Bykovskaia SN, Chen Q, Buffo MJ, Shogan J, et al. (1999) Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286:525-528
    • (1999) Science , vol.286 , pp. 525-528
    • Yang, D.1    Chertov, O.2    Bykovskaia, S.N.3    Chen, Q.4    Buffo, M.J.5    Shogan, J.6
  • 14
    • 84870928866 scopus 로고    scopus 로고
    • Effect of bowel cleansing for colonoscopy on fecal calprotectin levels in pediatric patients
    • 22614113 10.1097/MPG.0b013e31825f4c77
    • Kolho KL, Alfthan H, Hämäläinen E (2012) Effect of bowel cleansing for colonoscopy on fecal calprotectin levels in pediatric patients. J Pediatr Gastroenterol Nutr 55:751-753
    • (2012) J Pediatr Gastroenterol Nutr , vol.55 , pp. 751-753
    • Kolho, K.L.1    Alfthan, H.2    Hämäläinen, E.3
  • 15
    • 33745714449 scopus 로고    scopus 로고
    • Fecal calprotectin remains high during glucocorticoid therapy in children with inflammatory bowel disease
    • DOI 10.1080/00365520500419623, PII M634862R5716261G
    • Kolho KL, Raivio T, Lindahl H, Savilahti E (2006) Fecal calprotectin remains high during glucocorticoid therapy in children with inflammatory bowel disease. Scand J Gastroenterol 41:720-725 (Pubitemid 43995015)
    • (2006) Scandinavian Journal of Gastroenterology , vol.41 , Issue.6 , pp. 720-725
    • Kolho, K.-L.1    Raivio, T.2    Lindahl, H.3    Savilahti, E.4
  • 16
    • 77955701075 scopus 로고    scopus 로고
    • Faecal calprotectin in children with clinically quiescent inflammatory bowel disease
    • 1:CAS:528:DC%2BC3cXoslahs7s%3D 20377469 10.3109/00365521003782389
    • Sipponen T, Kolho K-L (2010) Faecal calprotectin in children with clinically quiescent inflammatory bowel disease. Scand J Gastroenterol 45:872-877
    • (2010) Scand J Gastroenterol , vol.45 , pp. 872-877
    • Sipponen, T.1    Kolho, K.-L.2
  • 17
    • 83755194964 scopus 로고    scopus 로고
    • Infliximab in pediatric inflammatory bowel disease rapidly decreases fecal calprotectin levels
    • 22215940 10.3748/wjg.v17.i47.5166
    • Hämäläinen A, Sipponen T, Kolho K-L (2011) Infliximab in pediatric inflammatory bowel disease rapidly decreases fecal calprotectin levels. World J Gastroenterol 17:5166-5171
    • (2011) World J Gastroenterol , vol.17 , pp. 5166-5171
    • Hämäläinen, A.1    Sipponen, T.2    Kolho, K.-L.3
  • 18
    • 84891860060 scopus 로고    scopus 로고
    • Fecal calprotectin and clinical disease activity in pediatric ulcerative colitis
    • doi: 10.1155/2013/179024
    • Kolho KL, Turner D (2013) Fecal calprotectin and clinical disease activity in pediatric ulcerative colitis.ISRN Gastroenterol. 2013:179024. doi: 10.1155/2013/179024.
    • (2013) ISRN Gastroenterol , vol.2013 , pp. 179024
    • Kolho, K.L.1    Turner, D.2
  • 19
    • 84857445043 scopus 로고    scopus 로고
    • Intestinal defensin secretion in infancy is associated with the emergence of sensitization and atopic dermatitis
    • 1:CAS:528:DC%2BC38XltFGrt78%3D 22093109 10.1111/j.1365-2222.2011.03904.x
    • Savilahti EM, Kukkonen AK, Haahtela T, Tuure T, Kuitunen M, Savilahti E (2012) Intestinal defensin secretion in infancy is associated with the emergence of sensitization and atopic dermatitis. Clin Exp Allergy 42:405-411
    • (2012) Clin Exp Allergy , vol.42 , pp. 405-411
    • Savilahti, E.M.1    Kukkonen, A.K.2    Haahtela, T.3    Tuure, T.4    Kuitunen, M.5    Savilahti, E.6
  • 23
    • 81455154734 scopus 로고    scopus 로고
    • Health-related quality of life in paediatric patients with inflammatory bowel disease related to disease activity
    • 21435075 10.1111/j.1440-1754.2011.02034.x
    • Haapamäki J, Roine RP, Sintonen H, Kolho KL (2011) Health-related quality of life in paediatric patients with inflammatory bowel disease related to disease activity. J Paediatr Child Health 47:832-837
    • (2011) J Paediatr Child Health , vol.47 , pp. 832-837
    • Haapamäki, J.1    Roine, R.P.2    Sintonen, H.3    Kolho, K.L.4
  • 24
    • 54049150524 scopus 로고    scopus 로고
    • Fecal calprotectin, lactoferrin, and endoscopic disease activity in monitoring anti-TNF-alpha therapy for Crohn's disease
    • 18484671 10.1002/ibd.20490
    • Sipponen T, Savilahti E, Kärkkäinen P, Kolho KL, Nuutinen H, Turunen U, Färkkilä M (2008) Fecal calprotectin, lactoferrin, and endoscopic disease activity in monitoring anti-TNF-alpha therapy for Crohn's disease. Inflamm Bowel Dis 14:1392-1398
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1392-1398
    • Sipponen, T.1    Savilahti, E.2    Kärkkäinen, P.3    Kolho, K.L.4    Nuutinen, H.5    Turunen, U.6    Färkkilä, M.7
  • 26
    • 84863986156 scopus 로고    scopus 로고
    • Limitations of fecal calprotectin at diagnosis in untreated pediatric Crohn's disease
    • 22275268 10.1002/ibd.21875
    • Shaoul R, Sladek M, Turner D, Paerregaard A, Veres G, Wauters G, et al. (2012) Limitations of fecal calprotectin at diagnosis in untreated pediatric Crohn's disease. Inflamm Bowel Dis 18:1493-1497
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1493-1497
    • Shaoul, R.1    Sladek, M.2    Turner, D.3    Paerregaard, A.4    Veres, G.5    Wauters, G.6
  • 27
    • 84861882865 scopus 로고    scopus 로고
    • The diagnostic accuracy of fecal calprotectin during the investigation of suspected pediatric inflammatory bowel disease
    • 1:CAS:528:DC%2BC38Xot1eqsb0%3D 22370604 10.1038/ajg.2012.33
    • Henderson P, Casey A, Lawrence SJ, Kennedy NA, Kingstone K, Rogers P, Gillett PM, Wilson DC (2012) The diagnostic accuracy of fecal calprotectin during the investigation of suspected pediatric inflammatory bowel disease. Am J Gastroenterol 107:941-949
    • (2012) Am J Gastroenterol , vol.107 , pp. 941-949
    • Henderson, P.1    Casey, A.2    Lawrence, S.J.3    Kennedy, N.A.4    Kingstone, K.5    Rogers, P.6    Gillett, P.M.7    Wilson, D.C.8
  • 28
    • 77955704585 scopus 로고    scopus 로고
    • Expression profiles of matrix metalloproteinases and their inhibitors in colonic inflammation related to pediatric inflammatory bowel disease
    • 20367198 10.3109/00365520903583863
    • Mäkitalo L, Kolho KL, Karikoski R, Anthoni H, Saarialho-Kere U (2010) Expression profiles of matrix metalloproteinases and their inhibitors in colonic inflammation related to pediatric inflammatory bowel disease. Scand J Gastroenterol 45:862-871
    • (2010) Scand J Gastroenterol , vol.45 , pp. 862-871
    • Mäkitalo, L.1    Kolho, K.L.2    Karikoski, R.3    Anthoni, H.4    Saarialho-Kere, U.5
  • 29
    • 0038529391 scopus 로고    scopus 로고
    • The expression of matrix metalloproteinase matrilysin indicates the degree of inflammation in ulcerative colitis
    • DOI 10.1007/s005350300062
    • Matsuno K, Adachi Y, Yamamoto H, Goto A, Arimura Y, Endo T, Itoh F, Imai K (2003) The expression of matrix metalloproteinase matrilysin indicates the degree of inflammation in ulcerative colitis. J Gastroenterol 38:348-354 (Pubitemid 36626270)
    • (2003) Journal of Gastroenterology , vol.38 , Issue.4 , pp. 348-354
    • Matsuno, K.1    Adachi, Y.2    Yamamoto, H.3    Goto, A.4    Arimura, Y.5    Endo, T.6    Itoh, F.7    Imai, K.8
  • 30
    • 33750510695 scopus 로고    scopus 로고
    • Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: A precancerous potential?
    • DOI 10.1097/01.mib.0000234133.97594.04, PII 0005472520061100000002
    • Rath T, Roderfeld M, Graf J, Wagner S, Vehr AK, Dietrich C, Geier A, Roeb E (2006) Enhanced expression of MMP-7 and MMP-13 in inflammatory bowel disease: a precancerous potential? Inflamm Bowel Dis 12:1025-1035 (Pubitemid 44665472)
    • (2006) Inflammatory Bowel Diseases , vol.12 , Issue.11 , pp. 1025-1035
    • Rath, T.1    Roderfeld, M.2    Graf, J.3    Wagner, S.4    Vehr, A.-K.5    Dietrich, C.6    Geier, A.7    Roeb, E.8
  • 32
    • 84859505767 scopus 로고    scopus 로고
    • Correlation of MMP-3 and MMP-9 with Crohn's disease activity in children
    • 1:CAS:528:DC%2BC38Xisl2lsb8%3D 3282895 21997756 10.1007/s10620-011-1936-z
    • Kofla-Dlubacz A, Matusiewicz M, Iwanczak B (2012) Correlation of MMP-3 and MMP-9 with Crohn's disease activity in children. Dig Dis Sci 57:706-712
    • (2012) Dig Dis Sci , vol.57 , pp. 706-712
    • Kofla-Dlubacz, A.1    Matusiewicz, M.2    Iwanczak, B.3
  • 33
    • 84862883383 scopus 로고    scopus 로고
    • The impact of matrix metalloproteinases and their tissue inhibitors in inflammatory bowel diseases
    • 22722554 10.1159/000336995
    • Lakatos G, Hritz I, Varga MZ, Juhász M, Miheller P, Cierny G, Tulassay Z, Herszényi L (2012) The impact of matrix metalloproteinases and their tissue inhibitors in inflammatory bowel diseases. Dig Dis 30:289-295
    • (2012) Dig Dis , vol.30 , pp. 289-295
    • Lakatos, G.1    Hritz, I.2    Varga, M.Z.3    Juhász, M.4    Miheller, P.5    Cierny, G.6    Tulassay, Z.7    Herszényi, L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.