The use of intravenous magnesium sulphate for acute migraine: Meta-analysis of randomized controlled trials

European Journal of Emergency Medicine

Volumn 21, Issue 1, 2014, Pages 2-9

  Choi, Hyun ^a   Parmar, Nandita ^a  

^a KINGSTON HOSPITAL   (United Kingdom)

Author keywords

headache; magnesium; migraine

Indexed keywords

MAGNESIUM SULFATE; METOCLOPRAMIDE; PLACEBO; PROCHLORPERAZINE;

ANALGESIA; DRUG EFFICACY; DRUG TOLERABILITY; HEADACHE; HUMAN; META ANALYSIS; MIGRAINE; PATIENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; UNSPECIFIED SIDE EFFECT;

ACUTE DISEASE; ADULT; DOPAMINE ANTAGONISTS; DOUBLE-BLIND METHOD; HUMANS; MAGNESIUM SULFATE; METOCLOPRAMIDE; MIGRAINE DISORDERS; PAIN MEASUREMENT; PROCHLORPERAZINE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT FAILURE;

EID: 84891860907     PISSN: 09699546     EISSN: 14735695     Source Type: Journal    
DOI: 10.1097/MEJ.0b013e3283646e1b     Document Type: Review

References (32)

1. Martin VT, Behbehani MM. Towards a rational understanding of migraine trigger factors. Med Clin North Am 2001; 85:911-941.
2. Sun-Edelstein C, Mauskop A. Role of magnesium in the pathogenesis and treatment of migraine. Expert Rev Neurother 2009; 9:369-379.
3. Jain AC, Sethi NC, Balbar PK. A clinical electronencephalographic and trace element study with special reference to zinc, copper and magnesium in serum and cerebrospinal fluid in cases of migraine. J Neurol 1985; 232:161.
4. Boska MD, Welch KMA, Barker PB, Nelson JA, Schultz L. Contrasts in cortical magnesium, phospholipid and energy metabolism between migraine syndromes. Neurology 2002; 58:1227-1233.
5. Ramadan NM, Halvorson H, Vande-Linde A, Levine SR, Helpern JA, Welch KM. Low brain magnesium in migraine. Headache 1989; 29:590-593.
6. Coan EJ, Collingridge GL. Magnesium ions block an N-methyl D-aspartate receptor-mediated component of synaptic transmission in rat hippocampus. Neurosci Lett 1985; 53:21-26.
7. Baudouin-Legros M, Dard B, Guichency P. Hyperreactivity of platelets from spontaneously hypertensive rats. Role of external magnesium. Hypertension 1986; 8:694-699.
8. Altura BT, Altura BM. Withdrawal of magnesium causes vasospasm while elevated magnesium produced relaxation of tone in cerebral arteries. Neurosci Lett 1989; 20:323-327.
9. Weglicki WB, Phillips TM. Pathobiology of magnesium deficiency: a cytokine/neurogenic inflammation hypothesis. Am J Physiol 1992; 263:R734-R737.
10. Ferrari MD. Biochemistry of migraine. Pathol Biol 1992; 40:287-292.
11. Mody I, Lambert JD, Heinemann U. Low extracellular magnesium induces epileptiform activity and spreading depression in rat hippocampal slices. J Neurophysiol 1987; 57:869-888.
12. Goldstein S, Zsoter TT. The effect of magnesium on the response of smooth muscle to 5-hydroxytryptamine. Br J Pharmacol 1978; 62:507-514.
13. Peikert A, Willimzig C, Kohne-Volland R. Prophylaxis of migraine with oral magnesium: results from a prospective multi-centre, placebo-controlled and double-blind randomised study. Cephalalgia 1996; 16:257-263.
14. Koseoglu E, Talashoglu A, Gonul AS, Kula M. The effects of magnesium prophylaxis in migraine without aura. Magnes Res 2008; 21:101-108.
15. Frank LR, Olson CM, Shuler KB, Gharib SF. Intravenous magnesium for acute benign headache in the emergency department: a randomised doubleblind placebo-controlled trial. CJEM 2004; 6:327-332.
16. Cete Y, Dora B, Ertan C, Ozdemir C, Oktay C. A randomised prospective placebo-controlled study of intravenous magnesium sulphate vs. metoclopramide in the management of acute migraine attacks in the emergency department. Cephalalgia 2005; 25:199-204.
17. Ginder S, Oatman B, Pollack M. A prospective study of IV magnesium and IV prochlorperazine in the treatment of headaches. J Emerg Med 2000; 18:311-315.
18. Corbo J, Esses D, Bijur PE, Iannaccone R, Gallagher EJ. Randomised clinical trial of intravenous magnesium sulphate as an adjunctive medication for emergency department treatment of migraine headache. Ann Emerg Med 2001; 38:621-627.
19. Bigal ME, Bordini CA, Tepper SJ, Speciali JG. Intravenous magnesium sulphate in the acute treatment of migraine without aura and migraine with aura. A randomised, double-blind, placebo-controlled study. Cephalalgia 2002; 22:345-353.
20. Demirkaya S, Vural O, Dora B, Topcuoglu MA. Efficacy of intravenous magnesium sulphate in the treatment of acute migraine attacks. Headache 2001; 41:171-177.
21. Zidverc-Trajkovic J, Pavlovic AM, Jovanovic Z, Sternic N, Kostic VS. Efficacy of intravenous magnesium sulphate in severe migraine attacks. J Headache Pain 2001; 2:79-82.
22. Mauskop A, Altura BT, Cracco RQ, Altura BM. Intravenous magnesium sulphate relieves migraine attacks in patients with low serum ionised magnesium levels: a pilot study. Clin Sci 1995; 89:633-636.
23. Mauskop A, Altura BT, Cracco RQ, Altura BM. Intravenous magnesium sulphate rapidly alleviates headaches of various types. Headache 1996; 36:154-160.
24. Coppola M, Yealy DM, Leibold RA. Randomized, placebo-controlled evaluation of prochlorperazine versus metoclopramide for emergency department treatment of migraine headache. Ann Emerg Med 1995; 26:541-546.
25. Jones J, Pack S, Chun E. Intramuscular prochlorperazine versus metoclopramide as single agent therapy for the treatment of acute migraine headache. Am J Emerg Med 1996; 14:262-264.
26. National Institute for Health and Care Excellence. Headaches: diagnosis and management of headaches in young people and adults, NICE Clinical Guideline 150. London: NICE 2012; Avaliable at: http://guidance.nice.org. uk/cg150 [Accessed 1 March 2013].
27. Tfelt-Hansen P, Pascual J, Ramadan N, Dahlof C, D'Amico D, Diener HC, et al. Guidelines for controlled trials of drugs in migraine: third edition. A guide for investigators. Cephalalgia 2012; 32:6-38.
28. Thomas SH, Stone K. Emergency department treatment of migraine, tension, and mixed-type headache. J Emerg Med 1994; 12:657-664.
29. Marcus DA. Migraine and tension-type headaches: the questionable validity of current classification systems. Clin J Pain 1992; 8:28-36.
30. Ellis GL, Delaney J, DeHart DA. The efficacy of metoclopramide in the treatment of migraine headache. Ann Emerg Med 1993; 22: 191-195.
31. Tek DS, McClellan DS, Olshaker JS, Allen CL, Arthur DC. A prospective, double-blind study of metoclopramide hydrochloride for the control of migraine in the emergency department. Ann Emerg Med 1990; 19:1083-1087.
32. Bell R, Montoya D, Shuaib A. A comparative trial of three agents in the treatment of acute migraine headache. Ann Emerg Med 1990; 19:1079-1082.