Polymerase chain reaction for Enterococcus faecalis in drain fluid: The first screening test for symptomatic colorectal anastomotic leakage. The Appeal-study: Analysis of Parameters Predictive for Evident Anastomotic Leakage

International Journal of Colorectal Disease

Volumn 29, Issue 1, 2014, Pages 15-21

  Komen, Niels ^a,b   Slieker, Juliette ^a   Willemsen, Paul ^b   Mannaerts, Guido ^c   Pattyn, Piet ^d   Karsten, Tom ^e   De Wilt, Hans ^a,f   Van Der Harst, Erwin ^g   Van Leeuwen, Willem ^a   Decaestecker, Christine ^h   Jeekel, Hans ^a   Lange, Johan F ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ZNA Middelheim ^*  (Belgium)

^c SINT FRANCISCUS GASTHUIS   (Netherlands)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

^e REINIER DE GRAAF HOSPITAL   (Netherlands)

^f RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^g Maasstad Hospital   (Netherlands)

^h UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Anastomotic leakage; Colorectal surgery; E. faecalis; Real time polymerase chain reaction; Screening

Indexed keywords

ABDOMINAL ABSCESS; ABDOMINAL DRAIN; ABDOMINAL DRAINAGE; ADULT; AGED; ANASTOMOSIS LEAKAGE; ARTICLE; BACTERIUM DETECTION; COLON RESECTION; COLORECTAL ANASTOMOSIS; COLORECTAL CANCER; CONTROLLED STUDY; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FEMALE; HEMICOLECTOMY; HUMAN; INFLAMMATORY BOWEL DISEASE; ISCHEMIC COLITIS; LAPAROTOMY; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTICENTER STUDY; OBSERVATIONAL STUDY; PELVIS ABSCESS; PERITONITIS; POSTOPERATIVE PERIOD; PREDICTIVE VALUE; PREOPERATIVE RADIOTHERAPY; PRIORITY JOURNAL; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SEPSIS; SIGMOIDECTOMY; SURGICAL INFECTION; YOUNG ADULT;

ANASTOMOTIC LEAK; DRAINAGE; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FEMALE; HUMANS; MALE; MASS SCREENING; MIDDLE AGED; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84891858406     PISSN: 01791958     EISSN: 14321262     Source Type: Journal    
DOI: 10.1007/s00384-013-1776-8     Document Type: Article

References (32)

1. Levack M, Berger D, Sylla P, Rattner D, Bordeianou L (2011) Laparoscopy decreases anastomotic leak rate in sigmoid colectomy for diverticulitis. Arch Surg 146(2):207-210
2. Boccola MA, Buettner PG, Rozen WM, Siu SK, Stevenson AR, Stitz R, et al. (2011) Risk factors and outcomes for anastomotic leakage in colorectal surgery: a single-institution analysis of 1576 patients. World J Surg 35(1):186-195
3. Matthiessen P, Hallbook O, Rutegard J, Simert G, Sjodahl R (2007) Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial. Ann Surg 246(2):207-214 (Pubitemid 47196517)
4. Fraccalvieri D, Biondo S, Saez J, Millan M, Kreisler E, Golda T, et al. (2012) Management of colorectal anastomotic leakage: differences between salvage and anastomotic takedown. Am J Surg 204(5):671-676
5. Buchs NC, Gervaz P, Secic M, Bucher P, Mugnier-Konrad B, Morel P (2008) Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study. Int J Colorectal Dis 23(3):265-270
6. Hyman N, Manchester TL, Osler T, Burns B, Cataldo PA (2007) Anastomotic leaks after intestinal anastomosis: it's later than you think. Ann Surg 245(2):254-258 (Pubitemid 46148485)
7. Bellows CF, Webber LS, Albo D, Awad S, Berger DH (2009) Early predictors of anastomotic leaks after colectomy. Tech Coloproctol 13(1):41-47
8. Macarthur DC, Nixon SJ, Aitken RJ (1998) Avoidable deaths still occur after large bowel surgery. Scottish audit of surgical mortality, royal college of surgeons of Edinburgh. Br J Surg 85(1):80-83 (Pubitemid 28034118)
9. Alves A, Panis Y, Pocard M, Regimbeau JM, Valleur P (1999) Management of anastomotic leakage after nondiverted large bowel resection. J Am Coll Surg 189(6):554-559
10. den Dulk M, Noter SL, Hendriks ER, Brouwers MA, van der Vlies CH, Oostenbroek RJ, et al. (2009) Improved diagnosis and treatment of anastomotic leakage after colorectal surgery. Eur J Surg Oncol 35(4):420-426
11. Marteau P, Pochart P, Dore J, Bera-Maillet C, Bernalier A, Corthier G (2001) Comparative study of bacterial groups within the human cecal and fecal microbiota. Appl Environ Microbiol 67(10):4939-4942 (Pubitemid 33646136)
12. Balamurugan R, Rajendiran E, George S, Samuel GV, Ramakrishna BS (2008) Real-time polymerase chain reaction quantification of specific butyrate-producing bacteria, Desulfovibrio and Enterococcus faecalis in the feces of patients with colorectal cancer. J Gastroenterol Hepatol 23(8 Pt 1):1298-1303
13. Komen N, Morsink MC, Beiboer S, Miggelbrink A, Willemsen P, van der Harst E, et al. (2009) Detection of colon flora in peritoneal drain fluid after colorectal surgery: can RT-PCR play a role in diagnosing anastomotic leakage? J Microbiol Methods 79(1):67-70
14. Fouda E, El Nakeeb A, Magdy A, Hammad EA, Othman G, Farid M (2011) Early detection of anastomotic leakage after elective low anterior resection. J Gastrointest Surg 15(1):137-144
15. Goligher JC, Lee PW, Simpkins KC, Lintott DJ (1977) A controlled comparison one- and two-layer techniques of suture for high and low colorectal anastomoses. Br J Surg 64(9):609-614 (Pubitemid 8170079)
16. Lim M, Akhtar S, Sasapu K, Harris K, Burke D, Sagar P, et al. (2006) Clinical and subclinical leaks after low colorectal anastomosis: a clinical and radiologic study. Dis Colon Rectum 49(10):1611-1619 (Pubitemid 44796134)
17. Doeksen A, Tanis PJ, Wust AF, Vrouenraets BC, van Lanschot JJ, van Tets WF (2008) Radiological evaluation of colorectal anastomoses. Int J Colorectal Dis 23(9):863-868
18. Hoffmann J, Jensen RH, Shokouh-Amiri MH, Damm P (1988) Clinical value of water-soluble contrast enema in assessing the integrity of left colonic anastomoses. J R Coll Surg Edinb 33(1):23-24
19. Akyol AM, McGregor JR, Galloway DJ, George WD (1992) Early postoperative contrast radiology in the assessment of colorectal anastomotic integrity. Int J Colorectal Dis 7(3):141-143
20. Nicksa GA, Dring RV, Johnson KH, Sardella WV, Vignati PV, Cohen JL (2007) Anastomotic leaks: what is the best diagnostic imaging study? Dis Colon Rectum 50(2):197-203 (Pubitemid 46227216)
21. Khoury W, Ben-Yehuda A, Ben-Haim M, Klausner JM, Szold O (2009) Abdominal computed tomography for diagnosing postoperative lower gastrointestinal tract leaks. J Gastrointest Surg 13(8):1454-1458
22. Averbach AM, Sugarbaker PH (1995) The use of drains in elective surgery for colorectal cancer: always, never or selectively? Tumori 81(3 Suppl):89-97
23. Brown SR, Seow-Choen F, Eu KW, Heah SM, Tang CL (2001) A prospective randomised study of drains in infra-peritoneal rectal anastomoses. Tech Coloproctol 5(2):89-92 (Pubitemid 33054533)
24. Lennox MS (1984) Prophylactic drainage of colonic anastomoses. Br J Surg 71(1):10-11 (Pubitemid 14214644)
25. Merad F, Yahchouchi E, Hay JM, Fingerhut A, Laborde Y, Langlois-Zantain O (1998) Prophylactic abdominal drainage after elective colonic resection and suprapromontory anastomosis: a multicenter study controlled by randomization. French Associations for Surgical Research. Arch Surg 133(3):309-314 (Pubitemid 28154995)
26. Jesus EC, Karliczek A, Matos D, Castro AA, Atallah AN (2004) Prophylactic anastomotic drainage for colorectal surgery. Cochrane Database Syst Rev 4, CD002100
27. Petrowsky H, Demartines N, Rousson V, Clavien PA (2004) Evidence-based value of prophylactic drainage in gastrointestinal surgery: a systematic review and meta-analyses. Ann Surg 240(6):1074-1084, discussion 84-5 (Pubitemid 39602134)
28. Yeh CY, Changchien CR, Wang JY, Chen JS, Chen HH, Chiang JM, et al. (2005) Pelvic drainage and other risk factors for leakage after elective anterior resection in rectal cancer patients: a prospective study of 978 patients. Ann Surg 241(1):9-13 (Pubitemid 40040987)
29. Peeters KC, Tollenaar RA, Marijnen CA, Klein Kranenbarg E, Steup WH, Wiggers T, et al. (2005) Risk factors for anastomotic failure after total mesorectal excision of rectal cancer. Br J Surg 92(2):211-216 (Pubitemid 40269337)
30. Karliczek A, Jesus EC, Matos D, Castro AA, Atallah AN, Wiggers T (2006) Drainage or nondrainage in elective colorectal anastomosis: a systematic review and meta-analysis. Colorectal Dis 8(4):259-265
31. Scatizzi M, Kroning KC, Boddi V, De Prizio M, Feroci F (2010) Fast-track surgery after laparoscopic colorectal surgery: is it feasible in a general surgery unit? Surgery 147(2):219-226
32. WHO. World Health Organization: Cancer 2011