Small molecule proprotein convertase inhibitors for inhibition of embryo implantation

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Ho, Huiting ^a,b   Singh, Harmeet ^a   Heng, Sophea ^a,b   Nero, Tracy L ^c   Paule, Sarah ^a   Parker, Michael W ^c,d   Johnson, Alan T ^e   Jiao, Guan Sheng ^e   Nie, Guiying ^a,b  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e PanThera Biopharma LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5 DIDEOXYSTREPTAMINE DERIVATIVE; ALPHA5 INTEGRIN; CONTRACEPTIVE AGENT; PROPROTEIN CONVERTASE 6; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL ASSAY; CHEMICAL ANALYSIS; COMPUTER MODEL; CONTROLLED STUDY; DECIDUALIZATION; DRUG EFFICACY; DRUG POTENCY; EMBRYO; ENDOMETRIUM CELL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOPHILICITY; NIDATION; PROTEIN CLEAVAGE; SPHEROID CELL; STROMA CELL; TROPHOBLAST;

CATALYTIC DOMAIN; CELL LINE; COMPUTER SIMULATION; DECIDUA; EMBRYO IMPLANTATION; ENDOMETRIUM; EPITHELIAL CELLS; FEMALE; HUMANS; INTEGRIN ALPHAV; LIPIDS; MODELS, MOLECULAR; MOLECULAR WEIGHT; PREGNANCY; PROPROTEIN CONVERTASE 5; PROTEASE INHIBITORS; SMALL MOLECULE LIBRARIES; SPHEROIDS, CELLULAR; STROMAL CELLS;

EID: 84891848842     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081380     Document Type: Article

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