Postconcussion syndrome (PCS) in the emergency department: Predicting and pre-empting persistent symptoms following a mild traumatic brain injury

Emergency Medicine Journal

Volumn 31, Issue 1, 2014, Pages 72-77

  Reuben, Adam ^a   Sampson, Paul ^b   Harris, Adrian Ralph ^a   Williams, Huw ^c   Yates, Phil ^a  

^a ROYAL DEVON AND EXETER HOSPITAL   (United Kingdom)

^b PENINSULA MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE STRESS; BRAIN CONCUSSION; EMERGENCY WARD; HIGH RISK PATIENT; HUMAN; INJURY SEVERITY; MEDICAL TERMINOLOGY; METHODOLOGY; NEUROLOGIC EXAMINATION; NEUROPATHOLOGY; PATIENT CARE; POSTCONCUSSION SYNDROME; PREDICTION; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; REVIEW; SCORING SYSTEM; SYMPTOM ASSESSMENT; TRAUMATIC BRAIN INJURY;

HEAD; PSYCHOLOGICAL CONDITIONS; TRAUMA, HEAD;

BRAIN CONCUSSION; BRAIN INJURIES; EMERGENCY SERVICE, HOSPITAL; HUMANS; STRESS DISORDERS, TRAUMATIC, ACUTE; SYNDROME;

EID: 84891842590     PISSN: 14720205     EISSN: 14720213     Source Type: Journal    
DOI: 10.1136/emermed-2012-201667     Document Type: Review

References (60)

1. Dikmen S, McLean A, Temkin N. Neuropsychological and psychosocial consequences of minor head injury. J Neurol Neurosurg Psych 1986;49:1227.
2. Kashluba S, Paniak C, Blake T, et al. A longitudinal, controlled study of patient complaints following treated mild traumatic brain injury. Arch Clin Neuropsych 2004;19:805.
3. Williams WH, Potter S, Ryland H. Mild traumatic brain injury and Postconcussion syndrome: a neuropsychological perspective. J Neurol Neurosurg Psych 2010;81:1116-22.
4. Malec J. DSM-IV postconcussional disorder: recommendations. J Neuropsychiatry Clin Neurosci 1996;8:113-14.
5. Boake C, McCauley SR, Levin HS, et al. Diagnostic criteria for postconcussional syndrome after mild to moderate traumatic brain injury. J Neuropsychiatry Clin Neurosci 2001;17:350-6.
6. Alexander MP. Mild traumatic brain injury: Pathophysiology, natural history, and clinical management. Neurol 1995;45:1253-60.
7. Menon DK, Schwab K, Wright DW, et al. Position statement: definition of traumatic brain injury. Arch Phys Med Rehabil 2010;91:1637-40.
8. McCrory P, Meeuwisse W, Johnston K, et al. Consensus statement on concussion in sport - the 3rd international conference on concussion in sport, November 2008. J Clin Neurosci 2009;16:755-63.
9. Sharp DJ, Greenwood R, Beckman CF, et al. Default mode network functional and structural connectivity after traumatic brain injury. Brain 2011;134:2233-47; doi:10. 1093/brain/awr175.
10. McCauley SR, Boake C, Pedroza C, et al. Postconcussional disorder: are the DSM-IV criteria an improvement over the ICD-10? J Nerv Ment Dis 2005;193:540.
11. King NS. Post-concussion syndrome: clarity amid the controversy? Br J Psychiatry 2003;183:276-8.
12. Tennant A. Admission to hospital following head injury in England: incidence and socioeconomic associations. BMC Public Health 2005;5:21.
13. Cunningham J. Concussive symptoms in Emergency Department patients with minor head injury. J Emerg Med 2011;40:262.
14. United States of America, National Institute of Neurological Disorders and Stroke (NINDS). Traumatic brain injury: hope through research. Bethesda, MD: National Institute of Health, 2002.
15. Ryan LM, Warden DL. Post concussion syndrome. Int Rev Psychiatry 2003;15:310-16.
16. Kashluba S, Paniak C, Casey JE. Persistent symptoms associated with factors identi fied by the WHO Task Force on Mild Traumatic Brain Injury. Clin Neuropsych 2008;22:195-208.
17. McCauley SR, Boake C, Levin HS, et al. Postconcussional disorder following mild to moderate traumatic brain injury; anxiety, depression and social support as risk factors and comorbidities. J Clin Exp Neuropsychol 2001;23:792.
18. Kant R, Smith-Seemiller L, Isaac G, et al. Tc-HMPAO SPECT in persistent post-concussion syndrome after mild head injury: comparison with MRI/CT. Brain Inj 1997;11:115.
19. Anderson T, Heitger M, Macleod AD. Concussion and mild head injury. Prac Neurol 2006;6:342-57.
20. Gavett BE, Stern RA, McKee AC. Chronic traumatic encephalopathy: a potential late effect of sport-related concussive and subconcussive head trauma. Clin Sports Med 2011;30:179-88.
21. McKee AC, Cantu RC, Nowinski CJ, et al. Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol 2009;68:709-35.
22. Brand AN, Jolles J. Information processing in depression and anxiety. Psychol Med 1987;14:621.
23. Fann JR, Uomoto JM, Katon WJ. Cognitive improvement with treatment of depression following mild traumatic brain injury. Psychosomatics 2001;42:48.
24. Jacobson RR. The post-concussional syndrome: physiogenesis, psychogenesis and malingering. An integrative model. J Psychosom Res 1995;39:675-93.
25. Hall RC, Chapman MJ. Definition, diagnosis and forensic implications of postconcussional syndrome. Psychosomatics 2005;46:195-202.
26. Bryant RA, Harvey AG. Postconcussive symptoms and posttraumatic stress disorder after mild traumatic brain injury. J Nerv Ment Dis 1999;187:302-5.
27. Hoge CW, McGurk D, Thomas JL, et al. Mild traumatic brain injury in U.S. soldiers returning from Iraq. N Engl J Med 2008;358:453-63.
28. National Institute for Clinical Health and Excellence Guideline CG56: Triage Assessment, Investigations and Early Management of Head Injury in Infants, Children and Adults. www.nice.org.uk/nicemedia/live/11836/36257/36257. pdf 2007 (accessed 05/2011).
29. de Kruijk JR, Leffers P, Menheere P, et al. Prediction of post traumatic complaints after mild traumatic brain injury: early symptoms and biochemical markers. J Neurol Neurosurg Psych 2002;73:727-32.
30. Broshek DK, Kaushik T, Freeman JR, et al. Sex differences in outcome following sports-related concussion. J Neurosurg 2005;102:856-63.
31. Sheedy JB, Harvey E, Faux S, et al. Emergency department assessment of mild traumatic brain injury and the prediction of post-concussive symptoms: a 3 month prospective study. J Head Trauma Rehabil 2009;24:333-43.
32. Bazarian JJ, Atabaki S. Predicting postconcussion syndrome after mild traumatic brain injury. Acad Emerg Med 2001;8:788-95.
33. McCrea M, Kelly JP, Randolph C, et al. Standardized assessment of concussion (SAC): on-site mental status evaluation of the athlete. J Head Trauma Rehabil 1998;13:27-35.
34. Crawford MA, Knight RG, Alsop BL. Speed of word retrieval in post concussion syndrome. J Int Neuropsychol Soc 2007;13:178-82.
35. King NS. Emotional, neuropsychological, and organic factors: their use in prediction of persisting postconcussion symptoms after moderate and mild ear injuries. J Neurol Neurosurg Psych 1996;61:75-81.
36. Maddocks D, Saling M. Neuropsychological deficits following concussion. Brain Inj 1996;19:99-104.
37. Townend WJ, Guy MJ, Pani MA. Head injury outcome prediction in the emergency department: a role for protein S-100B? J Neurol Neurosurg Psych 2002;73: 542-6.
38. Townsend W, Ingebrigtsen I. Head injury outcome prediction: a role for protein S-100B. Injury 2006;37:1098-108.
39. McCrea M, Kelly JP, Kluge J, et al. Standardized assessment of concussion in football players. Neurology 1997;48:586-8.
40. Barr WB, McCrea M. Sensitivity and specificity of standardizedneurocognitive testing immediately following sports concussion. J Int Neuropsychol Soc 2001;7:693-702.
41. Peterson SE, Stull MJ, Collins MW, et al. Neurocognitive function of emergency department patient with mild traumatic brain injury. Ann Emerg Med 2009;53:796-803.
42. Guskiewicz K. Postural stability assessment following concussion. Clin J Sports Med 2001;11:182-90.
43. Wilkins JC, McLeod TCV, Perrin DH. Performance on the balance error scoring system decreases after fatigue. J Athl Train 2004;39:156-61.
44. Chamelian L, Feinstein A. Outcome after mild to moderate traumatic brain injury: the role of dizziness. Arch Phys Med Rehabil 2004;85:1662-6.
45. Wetjen NM, Pichelmann MA, Atkinson JL. Second impact syndrome: concussion and secondary brain complications. J Am Coll Surg 2010;211:553-7.
46. Makdissi M, Darby D, Maruff P, et al. Natural history of concussion in sport: markers of severity and implications for management. Am J Sports Med 2010;38:464-71.
47. Schatz P, Pardini JE, Lovell MR, et al. Sensitivity and specificity of the ImPACT Test Battery for concussion in athletes. Arch Clin Neuropsychol 2006;21:91-9.
48. Early Management of adult patients with a head injury 2009. Scottish Intercollegiate Guidelines Network (SIGN). 2009. http://www.sign.ac.uk/pdf/ qrg110adult.pdf (accessed 05/2011).
49. Minderhoud JM, Boelens MEM, Huizenga J, et al. Treatment of minor head injuries. Clin Neurol Neurosurg 1980;82:127-40.
50. Ponsford J, Willmott C, Rothwell A, et al. Impact of early intervention on outcome after mild traumatic brain injury in children. Pediatrics 2001;6:1297-303.
51. Ponsford J, Willmott C, Rothwell A, et al. Impact of early intervention on outcome following mild head injury in adults. J Neurol Neurosurg Psych 2002;73:330-2.
52. Bell KR, Hoffman JH, Temkin NR, et al. The effect of telephone counselling on reducing post-traumatic symptoms after mild traumatic brain injury: a randomised trial. J Neurol Neurosurg Psych 2008;79:1275-81.
53. Mittenberg W, Canyock EM, Condit D, et al. Treatment of post-concussion syndrome following mild head injury. J Clin Exp Neuropsychol 2001;23:829-36.
54. Wade DT, Crawford S, Wenden FJ, et al. Does routine follow up after head injury help? A randomized controlled trial. J Neurol Neurosurg Psych 1997;62:478-84.
55. Wade DT, King NS, Wenden FJ, et al. Routine follow-up after head injury: a second randomised controlled trial. J Neurol Neurosurg Psych 1998;65:177-83.
56. Elgmark Andersson E, Emanuelson I, Bjorklund R, et al. Mild traumatic brain injuries: the impact of early intervention on late sequelae. Acta Neurochir 2007;149:151-60.
57. de Kruijk JR, Leffers P, Meerhoff S, et al. Effectiveness of bed rest after mild traumatic brain injury: a randomised trial of no versus six days of bed rest. J Neurol Neurosurg Psych 2002;73:167.
58. Relander M, Troupp H, Bjorksteinaf G. Controlled trial of treatment for cerebral concussion. BMJ 1972;4:777-9.
59. Kaye NS, Townsend JB. An open-label trial of donepezil (aricept) in the treatment of persons with mild traumatic brain injury. J Neuropsychiatry Clin Neurosci 2003;15:383.
60. Wright DW, Kellerman AL, Hertzberg VS, et al . ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury. Ann Emerg Med 2006;49:391-402.