A new type of monodisperse porous, hydrophilic microspheres with reactive chloroalkyl functionality: Synthesis and derivatization properties

Colloid and Polymer Science

Volumn 292, Issue 1, 2014, Pages 219-228

  Kip, Çiǧdem ^a   Maraş, Bilginur ^a   Evirgen, Oǧulcan ^a   Tuncel, Ali ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

4 Vinylbenzyl chloride; Glycidyl methacrylate; Ion exchange resin; Monodisperse porous beads; Stationary phase

Indexed keywords

ACRYLIC MONOMERS; ATOM TRANSFER RADICAL POLYMERIZATION; CHLORINE COMPOUNDS; ETHYLENE; FREE RADICAL REACTIONS; HYDROPHILICITY; ION EXCHANGE; ION EXCHANGE RESINS; IONS; POLYMERIZATION;

4-VINYLBENZYL CHLORIDES; CHROMATOGRAPHIC STATIONARY PHASIS; ETHYLENE DIMETHACRYLATE; GLYCIDYL METHACRYLATE; MONO-DISPERSE; SEEDED POLYMERIZATION; STATIONARY PHASE; SURFACE INITIATED-ATOM TRANSFER RADICAL POLYMERIZATION;

MICROSPHERES;

3 CHLORO 2 HYDROXYPROPYL METHACRYLATE; HYDROXYL GROUP; ION EXCHANGE RESIN; MICROSPHERE; MONOMER; TRIAZOLE; UNCLASSIFIED DRUG;

ARTICLE; ATOM TRANSFER RADICAL POLYMERIZATION; CHROMATOGRAPHY; CLICK CHEMISTRY; DERIVATIZATION; HYDROPHILICITY; HYDROPHOBICITY; ION EXCHANGE; MORPHOLOGY; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; SURFACE PROPERTY; SYNTHESIS;

EID: 84891820052     PISSN: 0303402X     EISSN: 14351536     Source Type: Journal    
DOI: 10.1007/s00396-013-3070-2     Document Type: Article

References (25)

1. Liang YC, Svec F, Frechet JMJ (1997) Preparation and functionalization of reactive monodisperse macroporous poly(chloromethylstyrene-co-styrene-co- divinylbenzene) beads by a staged templated suspension polymerization. J Polym Sci Part A Polym Chem 35:2631-2643
2. Li WH, Stover HDH (2000) Monodisperse cross-linked core-shell polymer microspheres by precipitation polymerization. Macromolecules 33:4354-4360
3. Kedem M, Margel S (2002) Synthesis and characterization of micrometer-sized particles of narrow size distribution with chloromethyl functionality on the basis of single-step swelling of uniform polystyrene template microspheres. J Polym Sci Part A Polym Chem 40:1342-1352
4. Buchmeiser MR, Sinner F, Mupa M, Wurst K (2000) Ring-opening metathesis polymerization for the preparation of surface-grafted polymer supports. Macromolecules 33:32-39
5. Masuda T, Kitahara K, Aikawa Y, Arai S (2002) High-performance liquid chromatographic separation of carbohydrates on a stationary phase prepared from polystyrene-based resin and novel amines. J Chromatogr A 961:89-96
6. Gong B, Li L, Zhu JX, Qiang K, Ren L (2005) Synthesis of monodisperse poly(chloromethyl-styrene-co-divinylbenzene) beads and their application in separation of biopolymers. J Sep Sci 28:2546-2550
7. Gawdzik B, Maciejewska M (2004) Synthesis of isobutyl maleate-divinylbenzene microspheres by different techniques of heterogeneous polymerizations. J Appl Polym Sci 91:2008-2015
8. Maciejewska M, Osypiuk J, Gawdzik B (2005) Preparation and characterization of the chromatographic properties of ethylene glycol dimethacrylate/divinylbenzene polymeric microspheres. J Polym Sci, Part A Polym Chem 43:3049-3058
9. Maciejewska M, Gawdzik B (2005) Preparation and porous structure characterization of 4,4′-diphenylmethane dimethacrylate/divinylbenzene polymeric particles. J Appl Polym Sci 95:863-870
10. Podkoscielna B, Bartnicki A, Gawdzik B (2009) Porous microspheres, copolymers of bis[4-(2-hydroxy-3-methacryloyloxypropoxy)phenyl]sulfide, and divinylbenzene as stationary phase for HPLC. J Appl Polym Sci 111:1257-1267
11. Petro M, Svec F, Frechet JMJ (1997) Monodisperse hydrolyzed poly(glycidyl methacrylate-co-ethylene dimethacrylate) beads as a stationary phase for normal-phase HPLC. Anal Chem 69:3131-3139
12. Zhang SH, Huang XA, Yao NS, Horvath C (2002) Preparation of monodisperse porous polymethacrylate microspheres and their application in the capillary electrochromatography of macrolide antibiotics. J Chromatogr A 948:193-201
13. Ferreira A, Bigan M, Blondeau D (2003) Optimization of a polymeric HPLC phase: poly(glycidyl methacrylate-co-ethylene dimethacrylate): influence of the polymerization conditions on the pore structure of macroporous beads. React Funct Polym 56:123-136
14. Gong BL, Zhu JX, Li L, Qiang KJ, Ren L (2006) Synthesis of non-porous poly(glycidyl methacrylate-co-ethylene dimethacrylate) beads and their application in separation of biopolymers. Talanta 68:666-672
15. Slater M, Snauko M, Svec F, Frechet JMJ (2006) "Click chemistry" in the preparation of porous polymer-based particulate stationary phases for mu-HPLC separation of peptides and proteins. Anal Chem 78:4969-4975
16. Unsal E, Elmas B, Çaǧlayan B, Tuncel M, PatIr S, Tuncel A (2006) Preparation of an ion-exchange chromatographic support by a "grafting from" strategy based on atom transfer radical polymerization. Anal Chem 78:5868
17. Lin Z, Huang H, Sun XB, Lin Y, Zhang L, Chen GN (2012) Monolithic column based on a poly(glycidyl methacrylate-co-4-vinylphenylboronic acid-co-ethylene dimethacrylate) copolymer for capillary liquid chromatography of small molecules and proteins. J Chromatogr A 1246:90-97
18. Elmas B, Tuncel M, YalcIn G, Senel S, Tuncel A (2005) Synthesis of uniform, fluorescent poly(glycidyl methacrylate) based particles and their characterization by confocal laser scanning microscopy. Coll Surf A 269:125-134
19. Unsal E, ÇamlI ST, Tuncel M, Senel S, Tuncel A (2004) Monodisperse-porous particles with different polarities by "modified seeded polymerization" and their use as chromatographic packing in HPLC. React Funct Polym 61:353-368
20. Nahum A, Horvath C (1981) Surface silanols in silica-bonded hydrocarbonaceous stationary phases: I. Dual retention mechanism in reversed-phase chromatography. J Chromatogr A 203:53
21. Nordborg A, Hilder EF (2009) Recent advances in polymer monoliths for ion-exchange chromatography. Anal Bioanal Chem 394:71
22. Alpert AJ (1990) Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds. J Chromatogr A 499:177
23. Tuncel A, Tuncel M, Salih B (1999) Electron microscopic observation of uniform macroporous particles. I. Effect of seed latex type and diluent. J Appl Polym Sci 71:2271-2290
24. Tuncel A, Tuncel M, Ergun B, Alagoz C, Bahar T (2002) Carboxyl carrying-large uniform latex particles. Coll Surf A 197:79-94
25. Cheng CM, Vanderhoff JW, El-Aasser MS (1992) Synthesis and characterization of monodisperse porous polymer particles. J Polym Sci Polym Chem Ed 30:235-244