An overview of statistical planning to address subgroups in confirmatory clinical trials

Journal of Biopharmaceutical Statistics

Volumn 24, Issue 1, 2014, Pages 72-93

  Koch, Gary G ^a   Schwartz, Todd A ^a  

^a University of North Carolina at Chapel Hill   (United States)

Author keywords

Complementary subgroups; Hochberg method; Inferential subgroups; Power adjusted inferiority criterion; Power adjusted significance level; Sample size planning for subgroups; Supportive subgroups

Indexed keywords

ARTICLE; CLINICAL TRIAL (TOPIC); FOOD AND DRUG ADMINISTRATION; HAZARD RATIO; HUMAN; PLANNING; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATORY TRACT DISEASE; SAMPLE SIZE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STRATIFICATION; URINARY TRACT INFECTION;

ALGORITHMS; CLINICAL TRIALS AS TOPIC; DATA INTERPRETATION, STATISTICAL; HUMANS; POPULATION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN; RESPIRATORY TRACT DISEASES; RISK REDUCTION BEHAVIOR; SAMPLE SIZE; SOCIOECONOMIC FACTORS; URINARY TRACT INFECTIONS; VASCULAR DISEASES;

EID: 84891810976     PISSN: 10543406     EISSN: 15205711     Source Type: Journal    
DOI: 10.1080/10543406.2013.856021     Document Type: Article

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