Development of a novel nanoparticle by dual modification with the pluripotential cell-penetrating peptide PepFect6 for cellular uptake, endosomal escape, and decondensation of an siRNA core complex Asako Mitsueda,1

Biopolymers

Volumn 100, Issue 6, 2013, Pages 698-704

  Shimatani, Yuri ^a   Ito, Masahiro ^a   Ohgita, Takashi ^a   Yamada, Asako ^a   Hama, Susumu ^a   Gräslund, Astrid ^b   Lindberg, Staffan ^c   Langel, Ülo ^c   Harashima, Hideyoshi ^d   Nakase, Ikuhiko ^e   Futaki, Shiroh ^e   Kogure, Kentaro ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d HOKKAIDO UNIVERSITY   (Japan)

^e KYOTO UNIVERSITY   (Japan)

Author keywords

Cell penetrating peptide; Decondensation; siRNA delivery

Indexed keywords

CELLS; CYTOLOGY; NUCLEOTIDES; PEPTIDES; RNA;

CELL-PENETRATING PEPTIDE; CYTOPLASMIC DELIVERY; DECONDENSATION; ENDOSOMAL ESCAPES; LUCIFERASE ACTIVITIES; MULTIFUNCTIONAL CELLS; NON-VIRAL DELIVERY SYSTEMS; SIRNA DELIVERY;

NANOPARTICLES;

CELL PENETRATING PEPTIDE; CHLOROQUINE; LUCIFERASE; NANOPARTICLE; PEPFECT6 PEPTIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; CELL TRANSPORT; CELLULAR DISTRIBUTION; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; ENZYME ACTIVITY; RNA INTERFERENCE; STATIC ELECTRICITY; ZETA POTENTIAL; CHEMISTRY; ENDOSOME; GENETIC TRANSFECTION; HUMAN;

CELL-PENETRATING PEPTIDES; ENDOSOMES; HUMANS; NANOPARTICLES; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84891720030     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.22310     Document Type: Article

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