Inducible overexpression of GLUT1 prevents mitochondrial dysfunction and attenuates structural remodeling in pressure overload but does not prevent left ventricular dysfunction

Journal of the American Heart Association

Volumn 2, Issue 5, 2013, Pages

  Pereira, Renata O ^a   Wende, Adam R ^a   Olsen, Curtis ^a   Soto, Jamie ^a   Rawlings, Tenley ^a   Zhu, Yi ^a   Anderson, Steven M ^b   Abel, E Dale ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac hypertrophy; Contractile function; Glucose utilization; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CARNITINE PALMITOYLTRANSFERASE; CYCLOPHILIN D; CYTOCHROME C OXIDASE; DOXYCYCLINE; GLUCOSE; GLUCOSE TRANSPORTER 1; HEMAGGLUTININ; IRON SULFUR PROTEIN; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; MESSENGER RNA; N ACETYLGLUCOSAMINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); VOLTAGE DEPENDENT ANION CHANNEL; INDUCIBLE NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; DISEASE EXACERBATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EX VIVO STUDY; GENE INDUCTION; GENE OVEREXPRESSION; GLUCOSE UTILIZATION; GLUT1 GENE; HEART CYCLE; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN MODIFICATION; PROTEIN SYNTHESIS; TRANSGENE; ANIMAL; BIOSYNTHESIS; HEART LEFT VENTRICLE FUNCTION; METABOLISM; MITOCHONDRION; PHYSIOLOGY; PRESSURE; TRANSGENIC MOUSE; CONTRACTILE FUNCTION;

ANIMALS; GLUCOSE TRANSPORTER TYPE 1; MALE; MICE; MICE, TRANSGENIC; MITOCHONDRIA; NITRIC OXIDE SYNTHASE TYPE II; PRESSURE; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

CARDIAC HYPERTROPHY; CONTRACTILE FUNCTION; GLUCOSE UTILIZATION; MITOCHONDRIA;

EID: 84891709280     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.113.000301     Document Type: Article

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